November 2022 PMID 35881665

Does topical minoxidil at concentrations higher than 5% provide additional clinical benefit?

Shreya Singh, Anant Patil, Nika Kianfar, Anna Waśkiel-Burnat, Lidia Rudnicka, Rodney Sinclair, Mohamad Goldust

Mentions

10
Peak: 1 in Aug 2022
across 3 sources since Aug 2022

Extended reach

44,134
potential audience

Total likes

1,168

Video views

40,218

Mentions per month

Aug 2022 – Sep 2025

Where it's discussed

  • X / Twitter4 posts
  • News4 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reveal a moderate level of engagement, with comments referencing the plateau effect at 7.5% concentrations and mentioning that higher concentrations might not offer added benefits, as seen in phrases like 'higher concentrations may not be more effective' and questions about FDA approval, indicating curiosity and contemplation about clinical practice implications.

AgreementModerate agreement

Most discussions acknowledge the findings that increasing minoxidil beyond 5% does not significantly improve outcomes, showing general agreement with the research.

InterestModerate interest

Participants are moderately interested, reflected by queries about FDA approval and efficacy, indicating curiosity but not highly passionate responses.

EngagementModerate engagement

The discussions involve some level of engagement through questions and references to scientific considerations, but lack in-depth analysis or debate.

ImpactNeutral impact

The overall impact appears limited as conversations mostly revolve around clarifications and implications rather than transformative insights or calls for change.

Abstract in brief

  • The text discusses whether higher-than-5% concentrations of topical minoxidil provide additional benefits for treating androgenetic alopecia (AGA), given that 5% solutions are already more effective than 2% solutions.
  • A review of existing scientific studies, including clinical trials and case reports found in PubMed, was conducted to evaluate the effectiveness and safety of using higher concentrations of minoxidil for hair loss.
  • The goal is to determine if increasing minoxidil concentration beyond 5% results in better clinical outcomes for patients with pattern hair loss.]

Top posts

Most liked on X and Bluesky
ビビリ@AGA治療歴5年
@bibiriaga · X

高濃度ミノキシジルの効果については、結果がわかれていて、まだ検証の余地がありそうですね ①ミノキシジル5%<15% ②ミノキシジル10%>5% AGAガイドラインではミノキシジル2%<5%は認められていますが、5%以上はずっと右肩上がりというより、どこかで天井がありそうですね https://t.co/A5WXUay9WN https://t.co/13gsmZdkvD

Mar 29, 2023 · 4 likes · 431 followers View post →
おんどり@薄毛泌尿器科医
@ondori_blog · X

参考文献 https://t.co/oVLRyCXUdN

Oct 16, 2024 · 3 likes · 1,026 followers View post →
Dr Aayush Gupta
@DrAayushGupta · X

Importantly, higher concentrations of topical minoxidil may not be more effective, with a plateau reaching at 7.5% concentrations (especially in PEG formulations), according to a recent paper in @ced_wiley https://t.co/bno8sP4IhJ 6/11

Aug 5, 2022 · 2 likes · 51 followers View post →
CED
@ced_journal · X

Which of the following is the US Food and Drug Administration (FDA)-approved indication for use of topical minoxidil? a) Alopecia areata. b) Androgenetic alopecia. c) Frontal fibrosing alopecia. d) Monilethrix. e) Chronic telogen effluvium. https://t.co/v5FmJULMY0

Feb 24, 2023 · 1 like · 2,408 followers View post →

All mentions

おんどり@薄毛泌尿器科医
@ondori_blog · X

参考文献 https://t.co/oVLRyCXUdN

Oct 16, 2024 · 3 likes · 1,026 followers View post →
ビビリ@AGA治療歴5年
@bibiriaga · X

高濃度ミノキシジルの効果については、結果がわかれていて、まだ検証の余地がありそうですね ①ミノキシジル5%<15% ②ミノキシジル10%>5% AGAガイドラインではミノキシジル2%<5%は認められていますが、5%以上はずっと右肩上がりというより、どこかで天井がありそうですね https://t.co/A5WXUay9WN https://t.co/13gsmZdkvD

Mar 29, 2023 · 4 likes · 431 followers View post →
CED
@ced_journal · X

Which of the following is the US Food and Drug Administration (FDA)-approved indication for use of topical minoxidil? a) Alopecia areata. b) Androgenetic alopecia. c) Frontal fibrosing alopecia. d) Monilethrix. e) Chronic telogen effluvium. https://t.co/v5FmJULMY0

Feb 24, 2023 · 1 like · 2,408 followers View post →
Dr Aayush Gupta
@DrAayushGupta · X

Importantly, higher concentrations of topical minoxidil may not be more effective, with a plateau reaching at 7.5% concentrations (especially in PEG formulations), according to a recent paper in @ced_wiley https://t.co/bno8sP4IhJ 6/11

Aug 5, 2022 · 2 likes · 51 followers View post →