August 2022 PMID 35982449

Molecular effects of the consumption of margarine and butter varying in trans fat composition: a parallel human intervention study.

Dominik Guggisberg, Kathryn J Burton-Pimentel, Barbara Walther, René Badertscher, Carola Blaser, Reto Portmann, Alexandra Schmid, Thomas Radtke, Hugo Saner, Nadine Fournier, Ueli Bütikofer, Guy Vergères

Mentions

10
Peak: 3 in Jun 2023
across 3 sources since Aug 2022

Extended reach

45,927
potential audience

Total likes

416

Video views

13,992

Mentions per month

Aug 2022 – Oct 2025

Where it's discussed

  • X / Twitter5 posts
  • Instagram3 posts
  • YouTube2 videos

AI synopsis

What people are saying

Discussions reflect a balanced interest, with posts mentioning the molecular impacts of different fats and highlighting the relevance to cardiovascular health, such as references to fatty acid profiles and inflammatory responses. The tone is analytical but accessible, emphasizing the potential importance of the findings for dietary recommendations.

AgreementModerate agreement

Most discussions align with the study's findings, acknowledging the differences in health effects between butter and margarine with varying trans fat content.

InterestModerate interest

Participants show moderate curiosity about how dietary fats impact health, often referencing metabolic and molecular effects.

EngagementModerate engagement

Conversations involve some level of technical detail and discussion of implications, indicating moderate engagement.

ImpactModerate impact

The debates suggest the research could influence dietary choices or policy discussions, showing a recognition of its significance.

Abstract in brief

  • The study explores the health impacts of different types of trans fatty acids (TFAs) from dairy versus margarine, linking dietary fat intake to conditions like inflammation and cardiovascular disease.
  • Forty-two healthy volunteers were observed over four weeks, consuming either margarine without TFAs, margarine with industrial TFAs, or butter with ruminant TFAs, and their blood and metabolic changes were measured.
  • Results showed significant differences in fatty acid profiles and metabolite responses between the diets, particularly distinguishing butter from margarine, while gene expression remained unchanged across the groups.

Top posts

Most liked on X and Bluesky
Dra. Maribel Lizarzábal | Health Coach
@soydramaribel · X

Fuente: Dominik Guggisberg (2022). Molecular effects of the consumption of margarine and butter varying in trans fat composition: a parallel human intervention study - PubMed. https://t.co/J6gr1vvpC3

Jun 26, 2023 · 2 likes · 16,485 followers View post →
Gregory Miller, Ph.D.
@drdairy50 · X

Molecular effects of the consumption of margarine and butter varying in trans fat composition https://t.co/X44zsYJsAo

Aug 23, 2022 · 1 like · 10,737 followers View post →
Transcriptomes
@transcriptomes · X

Molecular effects of the consumption of margarine and butter varying in trans fat composition... https://t.co/OLG0lMeKwF

Aug 20, 2022 · 1 like · 1,808 followers View post →
Clayton Camargos
@DrCamargosCN · X

Manteiga e margarina

Aug 29, 2023 · 1 like · 212 followers View post →

All mentions

Clayton Camargos
@DrCamargosCN · X

Manteiga e margarina

Aug 29, 2023 · 1 like · 212 followers View post →
Dra. Maribel Lizarzábal | Health Coach
@soydramaribel · X

Fuente: Dominik Guggisberg (2022). Molecular effects of the consumption of margarine and butter varying in trans fat composition: a parallel human intervention study - PubMed. https://t.co/J6gr1vvpC3

Jun 26, 2023 · 2 likes · 16,485 followers View post →
Krzysztof Potempa
@BRAINCURES · X

@paulpetertak @robertlufkinmd Molecular effects of the consumption of margarine and butter varying in trans fat composition: a parallel human intervention study -Dominik Guggisberg, ... , Thomas Radtke, Hugo Saner, @_NadineFournier, Ueli Bütikofer @Bueti123, Guy Vergères https://t.co/Jd98nVapGp

Jun 4, 2023 · 2,663 followers View post →
Gregory Miller, Ph.D.
@drdairy50 · X

Molecular effects of the consumption of margarine and butter varying in trans fat composition https://t.co/X44zsYJsAo

Aug 23, 2022 · 1 like · 10,737 followers View post →
Transcriptomes
@transcriptomes · X

Molecular effects of the consumption of margarine and butter varying in trans fat composition... https://t.co/OLG0lMeKwF

Aug 20, 2022 · 1 like · 1,808 followers View post →
Instagram
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Referências bibliográficas: https://doi.org/10.1186/s12944-022-01675-1. Mach F. et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid ...

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doi: 10.1186/s12944-022-01675-1 doi: 10.3945/an.115.009662 doi: 10.1111/nbu.12264 doi: 10.3390/antiox10010059. View all 659 comments.

Apr 4, 2025 View →