I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you so much to everyone who made this project possible!! @sarah_reisman https://t.co/5XONvJhjdp
A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids.
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Aug 2022 – Mar 2023Where it's discussed
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X / Twitter89 posts
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AI synopsis
What people are saying
Many participants expressed their excitement with phrases like 'finally live!' and 'incredible synthesis,' indicating a strong emotional connection to the work. The choice of enthusiastic language and emphasis on innovative synthesis methods reflects the community's recognition of the publication's relevance and potential impact.
The majority of discussions reflect strong support for the publication, highlighting its innovative approach.
There is a heightened curiosity around the synthesis method, as many users express enthusiasm.
While some discussions are surface-level, there are multiple references to specific techniques and implications that indicate deeper interest.
Participants perceive the research as significantly influential within the field of synthetic chemistry.
Abstract in brief
- The article discusses a new synthesis method for matrine and isomatrine, two tetracyclic alkaloids from traditional Chinese medicine.
- The method uses a dearomative annulation reaction, combining pyridine and glutaryl chloride to form the complete alkaloid structure in just one step.
- The synthesis of isomatrine is efficient, requiring only four steps from cheap, readily available chemicals, and allows for further production of related lupin alkaloids.
Top posts
Most liked on X and BlueskyToday on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the synthesis of lupin alkaloids with @Sarah_Reisman @Caltech! Full episode: https://t.co/S2EfZQXNad Key paper: @J_A_C_S 2022, 144, 15938. https://t.co/c5hoCJFjkZ https://t.co/OV0cHXEWp0
A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pik Hoi Lam, @houk1000 at @uclachem, and @sarah_reisman at @CaltechCCE https://t.co/0iLvhan2c2 https://t.co/sdQtC1gZyp
A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @CaltechCCE @uclachem @AnetaTurlik @houk1000 @kerkovius @sarah_reisman @Caltech @TotalSynthesis @TotalSyntheses #Dearomatization #Lupin #Alkaloids https://t.co/8VqUYIGcTG
In this week's #NSynthPick we highlight a pyridine dearomatization approach to prepare matrine-type alkaloids by @sarah_reisman @kerkovius @AnetaTurlik @houk1000 and co-workers from @CaltechCCE @uclachem published in @J_A_C_S https://t.co/HUPma6jnzg
A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm #news #Technology #Tech #NewsBreak #Trending #research #AcademicTwitter #science https://t.co/bIVnDoA6Ug https://t.co/rNItjfnqE2
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Key Papers in Organic Synthesis: September 2022 Highlights
In this video, I discuss five significant papers in organic synthesis published in September 2022. The spotlight includes new synthesis methods for alkaloids, highlighting efficient processes and innovative reactions…
A Pyridine Dearomatization Approach to the Matrine-type Lupin Alkaloids with Jeff Kerkovius
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
RT @MatthewHorwitz1: Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the s…
Today on Synthesis Workshop, Jeff @Kerkovius takes us through his work on a pyridine dearomatization approach to the synthesis of lupin alkaloids with @Sarah_Reisman @Caltech! Full episode: https://t.co/S2EfZQXNad Key paper: @J_A_C_S 2022, 144, 15938. https://t.co/c5hoCJFjkZ https://t.co/OV0cHXEWp0
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @NatureSynthesis: In this week's #NSynthPick we highlight a pyridine dearomatization approach to prepare matrine-type alkaloids by @sara…
RT @NatureSynthesis: In this week's #NSynthPick we highlight a pyridine dearomatization approach to prepare matrine-type alkaloids by @sara…
Congrats @sarah_reisman! Great lecture @ishc1967. Check out this incredible synthesis…https://t.co/6Z3NEKXpIu https://t.co/nuwAIqlndM
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @NatureSynthesis: In this week's #NSynthPick we highlight a pyridine dearomatization approach to prepare matrine-type alkaloids by @sara…
RT @NatureSynthesis: In this week's #NSynthPick we highlight a pyridine dearomatization approach to prepare matrine-type alkaloids by @sara…
RT @NatureSynthesis: In this week's #NSynthPick we highlight a pyridine dearomatization approach to prepare matrine-type alkaloids by @sara…
In this week's #NSynthPick we highlight a pyridine dearomatization approach to prepare matrine-type alkaloids by @sarah_reisman @kerkovius @AnetaTurlik @houk1000 and co-workers from @CaltechCCE @uclachem published in @J_A_C_S https://t.co/HUPma6jnzg
RT @InnovationChem: JACS online: A #Pyridine #Dearomatization Approach to the #Matrine-Type #Lupin #Alkaloids @CaltechCCE @uclachem @Ane…
RT @InnovationChem: JACS online: A #Pyridine #Dearomatization Approach to the #Matrine-Type #Lupin #Alkaloids @CaltechCCE @uclachem @Ane…
JACS online: A #Pyridine #Dearomatization Approach to the #Matrine-Type #Lupin #Alkaloids @CaltechCCE @uclachem @AnetaTurlik @houk1000 @kerkovius @sarah_reisman @Caltech @TotalSynthesis @TotalSyntheses @J_A_C_S #Chemistry #Technologies https://t.co/0cD98peAx4
4 steps!? A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids https://t.co/KDPPIebBaW
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @Blanchard_Lab: [ASAP] From @sarah_reisman : A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids https://t.co/BbEhX6…
こういう仕事を見ると、全合成研究にも頭の使いどころはまだまだあるんだなぁと思えてならない。独自技術を見せ場とするプレゼンに拘り、逆に全体効率を犠牲にしがちなのがそこらで良くみる話。そういう思想とは、根本的に捉え方が違っているように思う。 https://t.co/uNNISxaqje
今週の最新論文アップデートより ピリジンとジカルボニル化合物から四環性骨格を一挙に作る反応を利用してアルカロイドに誘導できた報告。 シンプルな原料からの一反応でできるプロダクトの複雑さがすごい。 こんな反応を設計してみたいものだ… https://t.co/aI6OGOIE4i
RT @isciverse: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicom…
RT @isciverse: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicom…
RT @J_A_C_S: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @CaltechCCE @uclachem @AnetaTurlik @houk1000 @kerkoviu…
[ASAP] From @sarah_reisman : A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids https://t.co/BbEhX6WC3o
RT @J_A_C_S: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @CaltechCCE @uclachem @AnetaTurlik @houk1000 @kerkoviu…
RT @J_A_C_S: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @CaltechCCE @uclachem @AnetaTurlik @houk1000 @kerkoviu…
RT @J_A_C_S: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @CaltechCCE @uclachem @AnetaTurlik @houk1000 @kerkoviu…
A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @CaltechCCE @uclachem @AnetaTurlik @houk1000 @kerkovius @sarah_reisman @Caltech @TotalSynthesis @TotalSyntheses #Dearomatization #Lupin #Alkaloids https://t.co/8VqUYIGcTG
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @isciverse: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicom…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @isciverse: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicom…
RT @isciverse: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicom…
A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm #news #Technology #Tech #NewsBreak #Trending #research #AcademicTwitter #science https://t.co/bIVnDoA6Ug https://t.co/rNItjfnqE2
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @TotalSynthesis: A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pi…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
RT @kerkovius: I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you…
A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids by @kerkovius, Andrea Stegner, @AnetaTurlik, Pik Hoi Lam, @houk1000 at @uclachem, and @sarah_reisman at @CaltechCCE https://t.co/0iLvhan2c2 https://t.co/sdQtC1gZyp
I'm soooo excited that it's finally live! A Pyridine Dearomatization Approach to the Matrine-Type Lupin Alkaloids! Thank you so much to everyone who made this project possible!! @sarah_reisman https://t.co/5XONvJhjdp