Throughout the discussions, participants explore the trial's findings, such as phrases like 'no difference in outcomes' and 'not affecting clinical practice,' which reflect a neutral tone acknowledging the results. The tone varies from analytical comments on the data to practical reflections, indicating high interest and engagement without claiming dramatic shifts in practice, thus supporting moderate impact. The use of specific trial details and references to clinical guidelines exemplifies the thorough engagement and interest in understanding the implications.
AgreementModerate agreement
Most discussions recognize that the study shows no significant difference between the two blood-pressure targets, indicating moderate agreement with the findings.
InterestHigh interest
Many comments highlight curiosity and reflection on the implications of the trial, showing high interest in the topic.
EngagementHigh engagement
Numerous posts reference specific data, trial details, and clinical practices, indicating deep engagement with the content.
ImpactModerate impact
Though the study may not radically change practice, several discussions consider its influence on post-resuscitation care protocols, demonstrating moderate impact.
Abstract in brief
A study investigated blood-pressure targets (63 mm Hg vs. 77 mm Hg) for comatose adults after out-of-hospital cardiac arrest to determine their impact on outcomes like survival and cognitive performance.
The trial included 789 patients and measured outcomes such as death rates and disability levels after 90 days, finding no significant difference between the two blood-pressure groups.
Results indicated similar survival rates, with 34% of patients in the high-target group and 32% in the low-target group experiencing primary outcome events, suggesting that the higher blood-pressure target may not provide additional benefits.
5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite outcome of mortality/severe disability/coma between MAP of 77 or 63 mmHg (34% vs 32% p=0.56)
Jan 1, 2023 · 52 likes · 23 shares · 5,154 followersView post →
OR
Orlando RPN
@OrlandoRPN · X
Estudio BOX
TAM meta 77 vs 63 mmHg en pacientes posparo cardiaco
Aug 27, 2022 · 50 likes · 12 shares · 94,127 followersView post →
TM
Tommaso Scquizzato, MD
@tscquizzato · X
#BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 41 likes · 28 shares · 5,154 followersView post →
JC
Jonathan Chávez
@JonathanNefro · X
Posterior a paro cardiopulmonar, mantener presión arterial media de 63mmHg, comparado a 77, fue similar en la probabilidad compuesta de morir o tener incapacidad severa (~32%), también en el desarrollo de daño renal agudo (10%)
En ensayo clínico
NEJM 2022
10.1056/NEJMoa2208687 https://t.co/KXmzLMNRvl
Aug 28, 2022 · 38 likes · 8 shares · 38,069 followersView post →
DD
Dansk Cardiologisk Selskab (DCS)
@cardio_dk · X
I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #ESCCongress
➡BOX blood pressure: https://t.co/keXiiKa6tu
➡BOX oxygen: https://t.co/MDbsWDtcCz
➡ADVOR: https://t.co/9iOlvxImaj
#DCSESC2022 #dkforsk https://t.co/Adq1Jmo2A5
Prof. Dr. Holger Thiele presents the central findings of his studies ECLSSHOCK and CAVAADHF at the European Society of Cardiology Congress. ECLSSHOCK explored whether ECLS improves outcomes in cardiogenic shock due to…
This study investigated blood-pressure targets for comatose adults after cardiac arrest to assess their impact on survival and cognitive outcomes. The trial included 789 patients and found no significant difference…
BOX Trail
⭐️ Has not affected my clinical practice immensely
⭐️ Aim for MAP >65mmHg
⭐️ Aim for O2 sat >90%
⭐️ Adjust for patient specific needs, 1 size does not fit all
https://t.co/DUv358QdAt
RT @SkylerLentz: @WardiGabriel @NickJohnsonMD @itisRebeccaSell @BenjaminAbella I liked this one, I always wondered about BP target post arr…
Feb 20, 2023 · 1 share · 2,265 followersView post →
SL
Skyler Lentz
@SkylerLentz · X
@WardiGabriel @NickJohnsonMD @itisRebeccaSell @BenjaminAbella I liked this one, I always wondered about BP target post arrest
Also cool methods, told to aim for MAP 70 and they adjusted monitor to read +\- 10%
https://t.co/9IFwNKaPLT
Feb 20, 2023 · 4 likes · 1 share · 3,914 followersView post →
DE
Dalne Eric
@EricDalne · X
RT @MetaphoreStudy: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM #BOX trial Our correspondence to authors publishe…
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM #BOX trial Our correspondence to authors published with @cariou_alain and @cguitton44 @NEJM Next steps: STEP CARE (NCT05564754) and METAPHORE (NCT 05486884) @AfterRosc. https://t.co/9BNf8arsOw
Jan 19, 2023 · 3 likes · 1 share · 23 followersView post →
DP
Dr. Rick Pescatore
@Rick_Pescatore · X
On shift discussing the BOX trial, which found no difference in post-cardiac arrest MAP targets of 77 vs 63. This was an informative trial for me, especially with previous data out of my alma mater suggesting MAP of 80 post-ROSC may be superior. https://t.co/iUs5JAHuOc https://t.co/ULG6cgVPgm
Jan 15, 2023 · 4 likes · 37,069 followersView post →
JH
Jamael Hoosain
@TheRealJamael · X
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 4, 2023 · 23 shares · 530 followersView post →
SM
Steven Mathern
@StevenMathern · X
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 2, 2023 · 23 shares · 472 followersView post →
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 1, 2023 · 23 shares · 2,035 followersView post →
SN
Syed Shahrul Naz
@drshahrul80 · X
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 1, 2023 · 23 shares · 6,933 followersView post →
KK
Kai Kirchhoff
@kaolki · X
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 1, 2023 · 23 shares · 108 followersView post →
LÜ
Luca Ünlü
@Luca_Uenlue · X
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 1, 2023 · 23 shares · 1,754 followersView post →
GM
Giovanni Landoni, MD
@giovannilandoni · X
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 1, 2023 · 23 shares · 4,749 followersView post →
CR
Cardiac Arrest Center - Ospedale San Raffaele
@SRCardiacArrest · X
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 1, 2023 · 23 shares · 622 followersView post →
R
ResusBot
@Resus_Bot · X
RT @tscquizzato: 5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite ou…
Jan 1, 2023 · 23 shares · 180 followersView post →
TM
Tommaso Scquizzato, MD
@tscquizzato · X
5⃣ Does targeting a MAP of 77 or 63 mmHg in pts resuscitated from OHCA improve outcomes?
➡️ No difference in composite outcome of mortality/severe disability/coma between MAP of 77 or 63 mmHg (34% vs 32% p=0.56)
Jan 1, 2023 · 52 likes · 23 shares · 5,154 followersView post →
Y
131yuki
@131yuki · X
【個人的2022年主要論文まとめ*NEJM編】
院外心停止、蘇生後昏睡患者における目標血圧
mBP
63
vs
77 mmHg
→90日以内の死亡もしくは重篤な脳神経障害に差なし
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/oBeO9u1h8W
@PatrickBering @bmorecardiology @AnnGageMD @MKIttlesonMD @tonkhueMdPhd @SusanJosephMD @GRamaniMD @gcfmd @WesElyMD @toddrice_ICU @DrJohnMcP Related concepts
Post cardiac arrest: MAP target 63 vs 77 = same outcomes
https://t.co/NCMBaUdg8D
But achieved MAP on inotropes in cardiogenic shock stratifies high & low risk groups
https://t.co/JEj3Omw79H
Dec 19, 2022 · 2 likes · 1,338 followersView post →
LH
Lucy Hogg
@lucyaadam · X
RT @sicsmembers: The BOX trial has 2 components shown below. Full papers can be found at https://t.co/zDAOoh36Ra and https://t.co/mqfwpCvXw…
Dec 16, 2022 · 2 shares · 174 followersView post →
SN
Syed Shahrul Naz
@drshahrul80 · X
RT @sicsmembers: The BOX trial has 2 components shown below. Full papers can be found at https://t.co/zDAOoh36Ra and https://t.co/mqfwpCvXw…
Dec 16, 2022 · 2 shares · 6,933 followersView post →
S
SICS
@sicsmembers · X
The BOX trial has 2 components shown below. Full papers can be found at https://t.co/zDAOoh36Ra and https://t.co/mqfwpCvXwz https://t.co/hYrOM2vFLw
Dec 16, 2022 · 7 likes · 2 shares · 2,161 followersView post →
AF
Ashish K. Khanna, MD,MS,FCCP,FCCM,FASA
@KhannaAshishCCM · X
RT @SCCM_Anesth: What is your MAP target in outside hospital cardiac arrest survivors? Kjaergaard et al in @NEJM in a double blind RCT comp…
Dec 15, 2022 · 1 share · 4,470 followersView post →
SS
SCCM Anesthesiology Section
@SCCM_Anesth · X
What is your MAP target in outside hospital cardiac arrest survivors? Kjaergaard et al in @NEJM in a double blind RCT compare 63 mmhg vs 77 mmHg MAP goals.
Link:https://t.co/nazdH7r51T https://t.co/OdDyvDywnW
Dec 15, 2022 · 4 likes · 1 share · 908 followersView post →
NL
Natalie Lavergne
@LavergneNatalie · X
RT @emergmedottawa: EMOttawa Journal Club
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest via @NEJM
Interpretation: For our…
Dec 13, 2022 · 4 shares · 1,230 followersView post →
DO
Diego Ortega
@Dhortega_rojas · X
RT @emergmedottawa: EMOttawa Journal Club
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest via @NEJM
Interpretation: For our…
RT @emergmedottawa: EMOttawa Journal Club
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest via @NEJM
Interpretation: For our…
Dec 13, 2022 · 4 shares · 1,331 followersView post →
R
ResusBot
@Resus_Bot · X
RT @emergmedottawa: EMOttawa Journal Club
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest via @NEJM
Interpretation: For our…
Dec 13, 2022 · 4 shares · 180 followersView post →
EO
EM Ottawa
@emergmedottawa · X
EMOttawa Journal Club
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest via @NEJM
Interpretation: For our practice we should continue to target a MAP of >65mmHg in a post arrest setting.
https://t.co/JRkO0q5EUj
#FOAMed #EmergencyMedicine https://t.co/jO20ywFtte
Dec 13, 2022 · 5 likes · 4 shares · 6,602 followersView post →
CC
Catherine R. Counts
@CatherineCounts · X
#ReSS22 Year in Review (Adults) Paper 14: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest https://t.co/NTuiZ8em19 https://t.co/ktCBCEP9DF
RT @WICSBottomLine: #TBL 419: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
https://t.co/23ZjINMba3
Article by Kjaergaard…
Nov 6, 2022 · 7 shares · 5,479 followersView post →
VM
Vanden Eede martin
@martin_vde · X
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest:
https://t.co/atBTxQNtM9
Pressure ≠ Perfusion
Sometimes less = more https://t.co/nPl56Y1bsQ
RT @CicuDr: MAP targets in comatose CA survivors:
63 mmHg vs. 77 mmHg - no clear differences in the outcomes.
https://t.co/e1k6mSt5AH
#CI…
Oct 30, 2022 · 1 share · 3,180 followersView post →
CT
CICU tweets
@CicuDr · X
MAP targets in comatose CA survivors:
63 mmHg vs. 77 mmHg - no clear differences in the outcomes.
https://t.co/e1k6mSt5AH
#CICU #NEJM #ICU #MedEd #CardioTwitter
Sekhon says that we tend to make the assumption that if we optimise flow and O2 content then we will have normal utilisation and diffusion - but the coupling with diffusion and utilisation isn’t in text
Mentions Box trial
https://t.co/PYgLOWmyCf
Oct 25, 2022 · 1 like · 14,074 followersView post →
C
Chandralekha
@Chandra12962937 · X
RT @arvindcanchi: This is interesting.
Targeting a mean arterial blood pressure of 77 mm Hg or 63 mm Hg in patients who had been resuscitat…
Oct 25, 2022 · 2 shares · 372 followersView post →
VR
Vasundhara Raghavan
@Vasuragh · X
RT @arvindcanchi: This is interesting.
Targeting a mean arterial blood pressure of 77 mm Hg or 63 mm Hg in patients who had been resuscitat…
Oct 24, 2022 · 2 shares · 2,679 followersView post →
IH
Irene Tatjer Hernanz
@Irene_tatjer · X
RT @resuscitology: In comatose survivors of cardiac arrest:
targeting a MAP of 77 mmHg vs 63 mmHg
https://t.co/eaT6vXedtq
&
restrictive…
This is interesting.
Targeting a mean arterial blood pressure of 77 mm Hg or 63 mm Hg in patients who had been resuscitated from cardiac arrest did not result in significantly different percentages of patients dying or having severe disability or coma. https://t.co/ycOSU8oqkE https://t.co/YZ0mSSlncH
Oct 24, 2022 · 2 likes · 2 shares · 11,003 followersView post →
JE
Justyna Swol MD • ECMOdaily
@ECMOdaily · X
RT @resuscitology: In comatose survivors of cardiac arrest:
targeting a MAP of 77 mmHg vs 63 mmHg
https://t.co/eaT6vXedtq
&
restrictive…
Oct 23, 2022 · 8 shares · 3,398 followersView post →
SS
Segun Olusanya (He/Him) iceman_ex@critcare.social
@iceman_ex · X
RT @resuscitology: In comatose survivors of cardiac arrest:
targeting a MAP of 77 mmHg vs 63 mmHg
https://t.co/eaT6vXedtq
&
restrictive…
Oct 23, 2022 · 8 shares · 19,686 followersView post →
NE
Nick Eastman
@docinaboxtruck · X
RT @resuscitology: In comatose survivors of cardiac arrest:
targeting a MAP of 77 mmHg vs 63 mmHg
https://t.co/eaT6vXedtq
&
restrictive…
Oct 23, 2022 · 8 shares · 166 followersView post →
A
AJPMD
@pulmccm2016 · X
RT @resuscitology: In comatose survivors of cardiac arrest:
targeting a MAP of 77 mmHg vs 63 mmHg
https://t.co/eaT6vXedtq
&
restrictive…
Oct 22, 2022 · 8 shares · 741 followersView post →
LK
Lee KC
@noohceekeel · X
RT @resuscitology: In comatose survivors of cardiac arrest:
targeting a MAP of 77 mmHg vs 63 mmHg
https://t.co/eaT6vXedtq
&
restrictive…
Oct 22, 2022 · 8 shares · 249 followersView post →
CR
Cliff Reid
@cliffreid · X
RT @resuscitology: In comatose survivors of cardiac arrest:
targeting a MAP of 77 mmHg vs 63 mmHg
https://t.co/eaT6vXedtq
&
restrictive…
Oct 22, 2022 · 8 shares · 45,071 followersView post →
R
Resuscitology
@resuscitology · X
In comatose survivors of cardiac arrest:
targeting a MAP of 77 mmHg vs 63 mmHg
https://t.co/eaT6vXedtq
&
restrictive vs liberal oxygenation strategy (Pao2 9-10 kPa (68-75 mmHg) vs 13-14 kPa (98-105 mmHg)
https://t.co/FM5nAVvFXJ
did not change death or severe disability https://t.co/92AQKoxr92
Oct 22, 2022 · 15 likes · 8 shares · 8,129 followersView post →
BR
Biomedical Research
@BiomedicalRese1 · X
Blood-Pressure Targets in Comatose Survivors of #Cardiac Arrest
For more: https://t.co/uDOkYaf9RA
Oct 20, 2022 · 1 share · 1,152 followersView post →
A
armyemdoc
@armyemdoc · X
Oct 20, 2022 · 2 likes · 1 share · 4,647 followersView post →
M
Meded
@cryptovitas · X
RT @PagingDrAyman: Blood Pressure Targets in Comatose Survivors of Cardiac Arrest: Targeting a MAP of 77 vs 63 mm Hg did not result in diff…
Oct 20, 2022 · 1 share · 3,180 followersView post →
AM
Ayman Soubani, MD
@PagingDrAyman · X
Blood Pressure Targets in Comatose Survivors of Cardiac Arrest: Targeting a MAP of 77 vs 63 mm Hg did not result in difference in patients dying or having severe disability or coma. See video link below. #medtwitter #meded
https://t.co/hBAK6Er8J9
https://t.co/gzpAg9pvuC
Oct 20, 2022 · 3 likes · 1 share · 156 followersView post →
BC
Bryan Cotton
@bryanacotton1 · X
Yep. Pretty consistent with previous work. No difference in survival aiming for higher BP.
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/pLzd9wsjr4
Oct 19, 2022 · 6 likes · 1 share · 5,044 followersView post →
MH
Med Peds Hospitalist
@medpedshosp · X
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/zujQ2Y30Bk
Oct 19, 2022 · 1 like · 14,320 followersView post →
ふ
ふろりあん
@ems4jhondo · X
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/IawCz0JRMP
4a/ Questions 4: Do aggressive vs liberal MAP or PaO2 targets impact outcomes following out-of-hospital cardiac arrest?
Trial to answer this: BOX Trial
https://t.co/B5HHgqOY5l
https://t.co/j4G5CZnVgv
RT @drdangayach: @ApnGreen @caseyalbin And look out for more cool stuff @JBLascarrou @fabio_taccone on what precision post resuscitation ca…
Oct 18, 2022 · 1 share · 1,219 followersView post →
NF
Neha Dangayach MD MSCR FAAN FANA FCCP FCCM FNCS
@drdangayach · X
@ApnGreen @caseyalbin And look out for more cool stuff @JBLascarrou @fabio_taccone on what precision post resuscitation care could look like-O2, CO2, BP (https://t.co/V9kus5i0ED), TTM, A2F…@sacagarw @PennTTM #NCS2022
Oct 18, 2022 · 2 likes · 1 share · 6,033 followersView post →
CB
Celia Bradford
@celiabradford · X
RT @WICSBottomLine: #TBL 419: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
https://t.co/23ZjINMba3
Article by Kjaergaard…
Oct 15, 2022 · 7 shares · 1,289 followersView post →
MP
Martin Frydland, MD, PhD
@joyland2704 · X
RT @WICSBottomLine: #TBL 419: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
https://t.co/23ZjINMba3
Article by Kjaergaard…
Oct 15, 2022 · 7 shares · 642 followersView post →
E
ECREM
@ECREM_UAE · X
RT @WICSBottomLine: #TBL 419: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
https://t.co/23ZjINMba3
Article by Kjaergaard…
Oct 14, 2022 · 7 shares · 180 followersView post →
DN
Dr Suresh Naidu
@sureshnaidu2012 · X
RT @WICSBottomLine: #TBL 419: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
https://t.co/23ZjINMba3
Article by Kjaergaard…
Oct 14, 2022 · 7 shares · 121 followersView post →
N
NYULangonePCCSM
@NYULangonePCCSM · X
Last week we had an excellent journal club on #cardiacarrest! check out what our fellows are reading from @NEJM
Oct 14, 2022 · 2 likes · 1 share · 2,371 followersView post →
QH
Quintard hervé
@QuintardH · X
RT @WICSBottomLine: #TBL 419: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
https://t.co/23ZjINMba3
Article by Kjaergaard…
Oct 14, 2022 · 7 shares · 162 followersView post →
CP
Carol Portugal
@carolportugal · X
RT @WICSBottomLine: #TBL 419: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
https://t.co/23ZjINMba3
Article by Kjaergaard…
Oct 14, 2022 · 7 shares · 308 followersView post →
TL
The Bottom Line
@WICSBottomLine · X
#TBL 419: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest
https://t.co/23ZjINMba3
Article by Kjaergaard @cardiac_group
Review by Brown https://t.co/bmnyziGnmc
Oct 14, 2022 · 10 likes · 7 shares · 20,949 followersView post →
MP
Marc Probst
@probstMD · X
What is the optimal BP target after OHCA?
No difference between 63 and 77 mmHg, as per new BOX trial in @NEJM
▶️DB-RCT from Denmark
▶️n=789 comatose adults with OHCA
▶️Target MAP of 63 vs 77 mmHg
▶️No difference in death or disability at 90 days
https://t.co/xtLEDq9jTB
Quelle est la tension artérielle optimale chez le patient après arrêt cardiorespiratoire : réponses de l’essai randomisé BOX : Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest https://t.co/lgA65qsuZr
...ni en el percentatge de pacients amb estat cerebral a l'alta molt desfavorable (*CPC 3-4). Els resultats han estat publicats en la revista NEJM.
Seguim en la cerca del Sant Greal en aquests pacients
Consulteu els articles:
2.- En pacientes en Coma tras PCR no hay diferencia en el pronóstico con objetivo de TAm entre 63 y 77 mm de Hg).
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest https://t.co/YD1GNhw1Z5
NEJM https://t.co/ib1b7OrLZq High (77 mmHg) vs low (63 mmHg) in comatose survivors OHCA requiring MV no diff 90-d death or severe disability https://t.co/0F5LtjSmGE
How are you managing your post cardiac arrest patients? Does BP make a difference? Here is one study - BP Targets in Comatose Survivors of Cardiac Arrest https://t.co/mtzFosyHp5
Un objetivo de PAM de 77mmHg vs 63mmHg en pacientes reanimados de un paro cardíaco no representó diferencias en mortalidad, discapacidad grave o coma (HR 1.08; P=0.56)
https://t.co/hzoeoJ6oWc https://t.co/asFysajdWl
I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #ESCCongress
➡BOX blood pressure: https://t.co/keXiiKa6tu
➡BOX oxygen: https://t.co/MDbsWDtcCz
➡ADVOR: https://t.co/9iOlvxImaj
#DCSESC2022 #dkforsk https://t.co/Adq1Jmo2A5
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM
No difference between high and low target BP
https://t.co/XUJPlcJgjD https://t.co/IhuYBSMrs1
Not TBI, but interesting 2 see higher BP goals did not improve outcomes after anoxic insult from arrest.
As 2 weird goal of 63 vs 77 mmHg, pretty sure it's payback 4 US not using metric system
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest https://t.co/vDIz6sbi7J
A new trial looks at MAP targets 63 vs 77 mmHg for out-of-hospital cardiac arrest. No difference in mortality at 90 days between the high vs low group. What is your MAP target for cardiac arrest? Link:https://t.co/V9ASj85wxD https://t.co/R4bcWZTnP3
RT @JonathanNefro: Posterior a paro cardiopulmonar, mantener presión arterial media de 63mmHg, comparado a 77, fue similar en la probabilid…
Aug 29, 2022 · 8 shares · 666 followersView post →
CR
Cardiac Arrest Center - Ospedale San Raffaele
@SRCardiacArrest · X
RT @YukiKotani5: Another RCT assessing “one-size-fits-all” #MAP targets failed to show benefits in intensive care settings (OHCA survivors…
Aug 29, 2022 · 4 shares · 622 followersView post →
R
ResusBot
@Resus_Bot · X
RT @YukiKotani5: Another RCT assessing “one-size-fits-all” #MAP targets failed to show benefits in intensive care settings (OHCA survivors…
Aug 29, 2022 · 4 shares · 180 followersView post →
小P
小谷祐樹 Yuki Kotani|ICU × 臨床研究 × Podcast
@YukiKotani5 · X
Another RCT assessing “one-size-fits-all” #MAP targets failed to show benefits in intensive care settings (OHCA survivors in this trial).
https://t.co/8bdIUgeV8p
Let's compare an individualized #hemodynamic strategy with usual care in future randomized trials.
#FOAMcc #FOAMed https://t.co/aFwXSzF8Nb
Aug 29, 2022 · 10 likes · 4 shares · 8,359 followersView post →
AG
alicia mabel gimenez
@aliciamabelgim1 · X
RT @JonathanNefro: Posterior a paro cardiopulmonar, mantener presión arterial media de 63mmHg, comparado a 77, fue similar en la probabilid…
Aug 28, 2022 · 8 shares · 323 followersView post →
SV
Sebastián Tenorio Vargas
@SebasTenorio · X
RT @JonathanNefro: Posterior a paro cardiopulmonar, mantener presión arterial media de 63mmHg, comparado a 77, fue similar en la probabilid…
Aug 28, 2022 · 8 shares · 534 followersView post →
DP
Dale Needham, MD, PhD
@DrDaleNeedham · X
RT @csmfisher: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/MtdeVrrjAM
Aug 28, 2022 · 5 shares · 11,569 followersView post →
I
Impack
@ImpackCPR · X
RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)
RT @JonathanNefro: Posterior a paro cardiopulmonar, mantener presión arterial media de 63mmHg, comparado a 77, fue similar en la probabilid…
Aug 28, 2022 · 8 shares · 4,456 followersView post →
RC
Ricardo Orozco C.
@Dr_Orozco_Nefro · X
RT @JonathanNefro: Posterior a paro cardiopulmonar, mantener presión arterial media de 63mmHg, comparado a 77, fue similar en la probabilid…
Aug 28, 2022 · 8 shares · 1,395 followersView post →
JC
Jonathan Chávez
@JonathanNefro · X
Posterior a paro cardiopulmonar, mantener presión arterial media de 63mmHg, comparado a 77, fue similar en la probabilidad compuesta de morir o tener incapacidad severa (~32%), también en el desarrollo de daño renal agudo (10%)
En ensayo clínico
NEJM 2022
10.1056/NEJMoa2208687 https://t.co/KXmzLMNRvl
Aug 28, 2022 · 38 likes · 8 shares · 38,069 followersView post →
GM
Guillermo Méndez
@Memo99373405 · X
RT @OrlandoRPN: Estudio BOX
TAM meta 77 vs 63 mmHg en pacientes posparo cardiaco
Aug 28, 2022 · 12 shares · 268 followersView post →
SN
Syed Shahrul Naz
@drshahrul80 · X
RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)
Aug 28, 2022 · 28 shares · 6,933 followersView post →
MZ
Mateusz Zawadka
@m_zawadka · X
RT @JacekGorka: Badanie BOX, którego wyniki opublikowano w @NEJM próbowało odpowiedzieć na pytania o cele terapeutyczne - MAP, pO2 u pacjen…
Aug 28, 2022 · 2 shares · 1,522 followersView post →
PG
Pierce Geoghegan
@geoghep · X
RT @PBSherren: Two important papers for the management of comatose OOHCA pts from the #esccongress2022. In this large RCT, with 2x2 factori…
Aug 28, 2022 · 3 shares · 418 followersView post →
CP
Cody Cunningham, MD, PhD
@CunninghamResus · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 28, 2022 · 28 shares · 403 followersView post →
JP
Jakub Fronczek, MD, PhD
@JFronczekMD · X
RT @JacekGorka: Badanie BOX, którego wyniki opublikowano w @NEJM próbowało odpowiedzieć na pytania o cele terapeutyczne - MAP, pO2 u pacjen…
Aug 28, 2022 · 2 shares · 477 followersView post →
JG
Jacek Gorka
@JacekGorka · X
Badanie BOX, którego wyniki opublikowano w @NEJM próbowało odpowiedzieć na pytania o cele terapeutyczne - MAP, pO2 u pacjentów po zatrzymaniu krążenia. Czy mamy kolejne dowody na LESS IS MORE? https://t.co/RvXT2IXc48, https://t.co/HPH8ggrgOq
Aug 28, 2022 · 1 like · 2 shares · 3,276 followersView post →
LH
Lene Holmvang
@LHolmvang · X
RT @cardio_dk: I dag præsenterende Jesper Kjærgaard @jek_kj blodtryks-delen af Box studiet
Studiet var statistisk neutralt, men rejste spæ…
Aug 28, 2022 · 3 shares · 640 followersView post →
S
Solo
@mingzibuganshuo · X
RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 1,338 followersView post →
EC
ERC - European Resuscitation Council
@ERC_resus · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 20,824 followersView post →
QH
Quintard hervé
@QuintardH · X
RT @fabio_taccone: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest - PubMed https://t.co/TDcyViblLC
Aug 27, 2022 · 5 shares · 162 followersView post →
AA
Ardak Arynov
@ArdakArynov · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 33 followersView post →
KC
Kitae (Tye) Chang
@tyechang · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 2,440 followersView post →
?
♰
@drmistico17 · X
RT @OrlandoRPN: Estudio BOX
TAM meta 77 vs 63 mmHg en pacientes posparo cardiaco
Aug 27, 2022 · 12 shares · 850 followersView post →
MQ
Malvado dr. quesillo
@trama_doc · X
RT @OrlandoRPN: Estudio BOX
TAM meta 77 vs 63 mmHg en pacientes posparo cardiaco
Aug 27, 2022 · 12 shares · 97 followersView post →
DH
Dr. Ernst David Hernández
@Akatoshk9 · X
RT @OrlandoRPN: Estudio BOX
TAM meta 77 vs 63 mmHg en pacientes posparo cardiaco
Aug 27, 2022 · 12 shares · 153 followersView post →
ST
Shaun Thompson
@slthomps12 · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 1,164 followersView post →
JS
Jasmeet Soar
@jas_soar · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 2,090 followersView post →
OR
Orlando RPN
@OrlandoRPN · X
Estudio BOX
TAM meta 77 vs 63 mmHg en pacientes posparo cardiaco
Aug 27, 2022 · 50 likes · 12 shares · 94,127 followersView post →
AF
Ashish K. Khanna, MD,MS,FCCP,FCCM,FASA
@KhannaAshishCCM · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 4,470 followersView post →
AF
Ashish K. Khanna, MD,MS,FCCP,FCCM,FASA
@KhannaAshishCCM · X
RT @giovannilandoni: Which #MAP Targets in Comatose Survivors of #CardiacArrest ?
At 90 days, 122 patients (31%) in the high-target group (…
Aug 27, 2022 · 5 shares · 4,470 followersView post →
JE
Justyna Swol MD • ECMOdaily
@ECMOdaily · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 3,398 followersView post →
D
drpaulinosegundo
@drpaulinosegun1 · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 141 followersView post →
DB
Denise Battaglini
@DeniseBatt25 · X
RT @fabio_taccone: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest - PubMed https://t.co/TDcyViblLC
Aug 27, 2022 · 5 shares · 821 followersView post →
CG
CRITICAL CARDIAC CARE RESEARCH GROUP
@cardiac_group · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 428 followersView post →
JJ
Jakob Josiassen
@JosiassenJakob · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 72 followersView post →
R
ResusBot
@Resus_Bot · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 180 followersView post →
CR
Cardiac Arrest Center - Ospedale San Raffaele
@SRCardiacArrest · X
RT @tscquizzato: #BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 28 shares · 622 followersView post →
TM
Tommaso Scquizzato, MD
@tscquizzato · X
#BOX_trial: WHICH MAP IN RESUSCITATED OHCA?
Aug 27, 2022 · 41 likes · 28 shares · 5,154 followersView post →
S
SVCardio
@SVCardio · X
RT @ValleAlfonso:
Aug 27, 2022 · 8 shares · 5,032 followersView post →
GM
Giovanni Landoni, MD
@giovannilandoni · X
Which #MAP Targets in Comatose Survivors of #CardiacArrest ?
At 90 days, 122 patients (31%) in the high-target group (77mmHg) and 114 patients (29%) in the low-target group (63mmHg) had died @NEJM
https://t.co/gqiwkd3JjZ
Aug 27, 2022 · 14 likes · 5 shares · 4,749 followersView post →
FT
Fabio Taccone
@fabio_taccone · X
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest - PubMed https://t.co/TDcyViblLC
Aug 27, 2022 · 15 likes · 5 shares · 1,630 followersView post →
NF
Nicolas FAGE
@nicolas_fage · X
RT @ChudeauN: Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM. No difference in rate of death or severe disability i…
Aug 27, 2022 · 8 shares · 513 followersView post →
CN
Chudeau Nicolas
@ChudeauN · X
Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | NEJM. No difference in rate of death or severe disability in OHCA patients resuscitated with high blood pressure targets @JohannesGrand @NEJM @AfterRosc https://t.co/FQatEDKKoo
Aug 27, 2022 · 5 likes · 1 share · 330 followersView post →
RC
Resi de Cardio
@RCardiologia · X
RT @ValleAlfonso:
Aug 27, 2022 · 8 shares · 154 followersView post →
HM
Harriette Van Spall, MD MPH
@hvanspall · X
RT @ValleAlfonso:
Aug 27, 2022 · 8 shares · 18,050 followersView post →
RG
Rajeev Gupta
@rajeevgg · X
In cardiac and medical ICUs we are always after target of MAP 65+: this trial resolves the issue. Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest | @NEJM https://t.co/Nt002dOGaj
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N Engl J Med 2022;387(16):1456-1466. resuscitation care. Intensive Care Med 2015; doi:10.1056/NEJMoa2208687 41(12):2039-2056. doi:10.1007/s00134-015-4051-3
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N Engl J Med 2022;387(16):1456-1466. resuscitation care. Intensive Care Med 2015; doi:10.1056/NEJMoa2208687 41(12):2039-2056. doi:10.1007/s00134-015-4051-3