N Engl J Med October 2022 PMID 36027567

Oxygen Targets in Comatose Survivors of Cardiac Arrest.

Henrik Schmidt, Jesper Kjaergaard, Christian Hassager, Simon Mølstrøm, Johannes Grand, Britt Borregaard, Laust E Roelsgaard Obling, Søren Venø, Laura Sarkisian, Dmitry Mamaev, Lisette O Jensen, Benjamin Nyholm, Dan E Høfsten, Jakob Josiassen, Jakob H Thomsen

Mentions

162
Peak: 62 in Aug 2022
across 5 sources since Aug 2022

Extended reach

519,590
potential audience

Total likes

332

Video views

2,405

Mentions per month

Aug 2022 – Oct 2025

Where it's discussed

  • X / Twitter142 posts
  • News10 articles
  • Facebook5 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone reflects a consensus that both oxygen strategies result in similar outcomes, illustrated by phrases like 'no difference in mortality or severe disability' and 'both arms remained in what most would consider normal range.' The frequent references to large trials like the BOX trial and ongoing studies such as MegaROX underline active, detailed engagement with evolving evidence, emphasizing the research's influence on clinical practice decisions.

AgreementStrong agreement

Most discussions support the findings, emphasizing no significant difference between restrictive and liberal oxygen strategies.

InterestHigh interest

Participants show high interest, referencing multiple trials, journal reviews, and ongoing studies, indicating active engagement with the research.

EngagementHigh engagement

Posts delve into methodological details, comparing outcomes from various trials, and discussing clinical implications, demonstrating deep engagement.

ImpactHigh impact

The discussions highlight that current evidence suggests changing practice may not be necessary, yet also recognize ongoing research, implying significant implications for clinical protocols.

Abstract in brief

  • The study investigated the best oxygen level for comatose survivors of out-of-hospital cardiac arrest, comparing restrictive (PaO of 9-10 kPa) and liberal (PaO of 13-14 kPa) oxygen targets.
  • Results showed no significant difference in primary outcomes (death or severe disability) within 90 days between the two groups, with similar mortality rates and neurological scores.
  • Overall, the findings suggest that maintaining a more restrictive oxygen target is as safe as a liberal approach for these patients.

Top posts

Most liked on X and Bluesky
Sarah Hudson
@sarahhudsonuk · X

7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictive (target PaO2 9-10kPa) or liberal (Pa02 13-14kPa) oxygen strategy during mechanical ventilation. Evidence: BOX https://t.co/vGfP94gbrc #ESCCongress https://t.co/rvC565HEo8

Aug 29, 2022 · 105 likes · 23 shares · 8,041 followers View post →
Dansk Cardiologisk Selskab (DCS)
@cardio_dk · X

I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #ESCCongress ➡BOX blood pressure: https://t.co/keXiiKa6tu ➡BOX oxygen: https://t.co/MDbsWDtcCz ➡ADVOR: https://t.co/9iOlvxImaj #DCSESC2022 #dkforsk https://t.co/Adq1Jmo2A5

Sep 5, 2022 · 24 likes · 5 shares · 747 followers View post →
Nick Johnson
@NickJohnsonMD · X

Reading in detail and pondering the recent, impressive #BOX trial. One takeaway is that both O2 arms remained in what most would consider normal range. https://t.co/uLeMlMdF3N 1/

Aug 29, 2022 · 22 likes · 7 shares · 6,542 followers View post →
こーすけ@救急医
@FlightDocKosuke · X

院外CPA蘇生後(昏睡)の酸素化目標についてのデンマークのRCT. 789名をPaO2:68-75mmHgの制限群,PaO2:98-105mmHg のリベラル群に割付. 神経予後は両群で有意差無し. 蘇生後の酸素目標はやや低めが良いかもという話が以前ありましたが…結局中庸に落ち着いていくのかもですね. https://t.co/lNrNybNUkY

Sep 2, 2022 · 22 likes · 1 share · 3,870 followers View post →
Manan Pareek, MD, MSc, PhD, FAHA, FESC
@MananPareekMD · X

The mini #ESCcongress continues - what’s in the BOX? @cardiac_group @RigsHeart https://t.co/s31TNTVEs2 https://t.co/nX7nybhmHE https://t.co/tT3SNUNBGG

Sep 20, 2022 · 20 likes · 2 shares · 956 followers View post →
Resuscitology
@resuscitology · X

In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive vs liberal oxygenation strategy (Pao2 9-10 kPa (68-75 mmHg) vs 13-14 kPa (98-105 mmHg) https://t.co/FM5nAVvFXJ did not change death or severe disability https://t.co/92AQKoxr92

Oct 22, 2022 · 15 likes · 8 shares · 8,129 followers View post →

All mentions

Irish Perioperative Medicine Society (IPOMS)
@IPOMS4 · X

In the BOX randomized trial, comatose survivors of OHCA were assigned to restrictive (PaO₂ 9–10 kPa) vs liberal (13–14 kPa) O₂ targets Death or severe neuro disability similar (32.0% vs 33.9%, HR 0.95, P=0.69) ➡️no benefit from lower O₂

Jun 9, 2025 · 921 followers View post →
Teddy Hla
@teddyhla · X

⚠️ Hyperoxia is harmful at 300mmHg. Hyperoxia is associated with cardiovascular failure. (mild) Hyperoxia is not harmful . BOX Trial https://t.co/PiXIWhVuym

Jun 19, 2023 · 1,508 followers View post →
Steven Mathern
@StevenMathern · X

RT @tscquizzato: 6️⃣ Does a PaO2 of mmHg 68-75 (restrictive) vs 98-105 (liberal) in resuscitated OHCA pts improve outcomes? ➡️ No differen…

Jan 2, 2023 · 6 shares · 472 followers View post →
Giovanni Landoni, MD
@giovannilandoni · X

RT @tscquizzato: 6️⃣ Does a PaO2 of mmHg 68-75 (restrictive) vs 98-105 (liberal) in resuscitated OHCA pts improve outcomes? ➡️ No differen…

Jan 1, 2023 · 6 shares · 4,749 followers View post →
Johannes Grand
@JohannesGrand · X

RT @tscquizzato: 6️⃣ Does a PaO2 of mmHg 68-75 (restrictive) vs 98-105 (liberal) in resuscitated OHCA pts improve outcomes? ➡️ No differen…

Jan 1, 2023 · 6 shares · 924 followers View post →
Cardiac Arrest Center - Ospedale San Raffaele
@SRCardiacArrest · X

RT @tscquizzato: 6️⃣ Does a PaO2 of mmHg 68-75 (restrictive) vs 98-105 (liberal) in resuscitated OHCA pts improve outcomes? ➡️ No differen…

Jan 1, 2023 · 6 shares · 622 followers View post →
CRITICAL CARDIAC CARE RESEARCH GROUP
@cardiac_group · X

RT @tscquizzato: 6️⃣ Does a PaO2 of mmHg 68-75 (restrictive) vs 98-105 (liberal) in resuscitated OHCA pts improve outcomes? ➡️ No differen…

Jan 1, 2023 · 6 shares · 428 followers View post →
ResusBot
@Resus_Bot · X

RT @tscquizzato: 6️⃣ Does a PaO2 of mmHg 68-75 (restrictive) vs 98-105 (liberal) in resuscitated OHCA pts improve outcomes? ➡️ No differen…

Jan 1, 2023 · 6 shares · 180 followers View post →
Tommaso Scquizzato, MD
@tscquizzato · X

6️⃣ Does a PaO2 of mmHg 68-75 (restrictive) vs 98-105 (liberal) in resuscitated OHCA pts improve outcomes? ➡️ No difference in mortality/severe disability between restrictive or liberal target in ICU (32% vs 34% p=.69)

Jan 1, 2023 · 7 likes · 6 shares · 5,154 followers View post →
131yuki
@131yuki · X

【個人的2022年主要論文まとめ*NEJM編】 心停止後の酸素投与ターゲット比較 restrictive vs liberal →アウトカム差なし ただし、 liberalでもPao2: 98 to 105 mm Hg restrictiveでは、Pao2: 68 to 75 mm Hg Oxygen Targets in Comatose Survivors of Cardiac Arrest | https://t.co/5N4bvSB9cu

Dec 21, 2022 · 2 likes · 279 followers View post →
Madiha Syed
@madihasyed85 · X

RT @SCCM_Anesth: In @NEJM authors look at oxygen targets in comatose survivors of cardiac arrest. The patients were randomized to oxygenat…

Dec 20, 2022 · 1 share · 229 followers View post →
SCCM Anesthesiology Section
@SCCM_Anesth · X

In @NEJM authors look at oxygen targets in comatose survivors of cardiac arrest. The patients were randomized to oxygenation goals of PaO2 68-75mmHg versus 98-105 mmHg. Again, no difference in death or neurologic outcomes. Negative trials win the day! https://t.co/mGPqiQtHRc

Dec 20, 2022 · 4 likes · 1 share · 908 followers View post →
Lucy Hogg
@lucyaadam · X

RT @sicsmembers: The BOX trial has 2 components shown below. Full papers can be found at https://t.co/zDAOoh36Ra and https://t.co/mqfwpCvXw…

Dec 16, 2022 · 2 shares · 174 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @sicsmembers: The BOX trial has 2 components shown below. Full papers can be found at https://t.co/zDAOoh36Ra and https://t.co/mqfwpCvXw…

Dec 16, 2022 · 2 shares · 6,933 followers View post →
SICS
@sicsmembers · X

The BOX trial has 2 components shown below. Full papers can be found at https://t.co/zDAOoh36Ra and https://t.co/mqfwpCvXwz https://t.co/hYrOM2vFLw

Dec 16, 2022 · 7 likes · 2 shares · 2,161 followers View post →
Conchi23
@Conchi30 · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/9mvNNOipQH

Nov 28, 2022 · 12 followers View post →
june660s
@june660s · X

メモ:他に2本、目標血圧とTTMの継続時間を検討した研究が発表されているが、いろんなエビデンスの蓄積、ケアの質の向上もあり今後一つの介入で予後を変えるような研究は少なくなってくるのか。でも大事。Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/RbBelqGjgN

Nov 11, 2022 · 67 followers View post →
Manuel Martinez MD
@manuelmtzmm · X

RT @WICSBottomLine: #TBL 420: Oxygen Targets in Comatose Survivors of Cardiac Arrest https://t.co/5czFSSYUvA Article by Henrik Schmidt @car…

Nov 8, 2022 · 4 shares · 48 followers View post →
ECREM
@ECREM_UAE · X

RT @WICSBottomLine: #TBL 420: Oxygen Targets in Comatose Survivors of Cardiac Arrest https://t.co/5czFSSYUvA Article by Henrik Schmidt @car…

Nov 8, 2022 · 4 shares · 180 followers View post →
Celia Bradford
@celiabradford · X

RT @WICSBottomLine: #TBL 420: Oxygen Targets in Comatose Survivors of Cardiac Arrest https://t.co/5czFSSYUvA Article by Henrik Schmidt @car…

Nov 8, 2022 · 4 shares · 1,289 followers View post →
Deborah Tooley
@dibitooley · X

RT @WICSBottomLine: #TBL 420: Oxygen Targets in Comatose Survivors of Cardiac Arrest https://t.co/5czFSSYUvA Article by Henrik Schmidt @car…

Nov 8, 2022 · 4 shares · 99 followers View post →
The Bottom Line
@WICSBottomLine · X

#TBL 420: Oxygen Targets in Comatose Survivors of Cardiac Arrest https://t.co/5czFSSYUvA Article by Henrik Schmidt @cardiac_group Review by @davidslessor https://t.co/DY9el7HzpA

Nov 8, 2022 · 13 likes · 4 shares · 20,949 followers View post →
CICU tweets
@CicuDr · X

O2 targets in comatose CA survivors: 9-10 kPa (68-75 mm Hg) vs. 13-14 kPa (98-105 mm Hg) - no clear differences in the outcomes. https://t.co/aJtK9Z1syH #CICU #NEJM #ICU #MedEd #CardioTwitter

Oct 30, 2022 · 3 likes · 213 followers View post →
Stacey Masters
@mast0052 · X

RT @reverendofdoubt: So many trials on this topic... going to need to wrap my brain around #BOXTrial, #PILOTtrial, the new #EXACTtrial... a…

Oct 29, 2022 · 3 shares · 142 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @resuscitology: In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive…

Oct 27, 2022 · 8 shares · 6,933 followers View post →
Katia Donadello
@KatiaDonadello · X

RT @reverendofdoubt: So many trials on this topic... going to need to wrap my brain around #BOXTrial, #PILOTtrial, the new #EXACTtrial... a…

Oct 26, 2022 · 3 shares · 1,219 followers View post →
Giovanni Landoni, MD
@giovannilandoni · X

RT @reverendofdoubt: So many trials on this topic... going to need to wrap my brain around #BOXTrial, #PILOTtrial, the new #EXACTtrial... a…

Oct 26, 2022 · 3 shares · 4,749 followers View post →
Joshua
@reverendofdoubt · X

So many trials on this topic... going to need to wrap my brain around #BOXTrial, #PILOTtrial, the new #EXACTtrial... and #MegaRox enrolling... thoughts from y'all? Pilot: https://t.co/TXInOtlP9v Box: https://t.co/NFqycxtxs9 Exact: https://t.co/ogS3Em7tfr https://t.co/BsWg8QJBCH

Oct 26, 2022 · 5 likes · 3 shares · 10,176 followers View post →
Irene Tatjer Hernanz
@Irene_tatjer · X

RT @resuscitology: In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive…

Oct 24, 2022 · 8 shares · 80 followers View post →
Biblioteca HUBA
@bibliohifc · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/zB92DNjuDo

Oct 24, 2022 · 87 followers View post →
Justyna Swol MD • ECMOdaily
@ECMOdaily · X

RT @resuscitology: In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive…

Oct 23, 2022 · 8 shares · 3,398 followers View post →
Segun Olusanya (He/Him) iceman_ex@critcare.social
@iceman_ex · X

RT @resuscitology: In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive…

Oct 23, 2022 · 8 shares · 19,686 followers View post →
Nick Eastman
@docinaboxtruck · X

RT @resuscitology: In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive…

Oct 23, 2022 · 8 shares · 166 followers View post →
AJPMD
@pulmccm2016 · X

RT @resuscitology: In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive…

Oct 22, 2022 · 8 shares · 741 followers View post →
Lee KC
@noohceekeel · X

RT @resuscitology: In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive…

Oct 22, 2022 · 8 shares · 249 followers View post →
Cliff Reid
@cliffreid · X

RT @resuscitology: In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive…

Oct 22, 2022 · 8 shares · 45,073 followers View post →
Resuscitology
@resuscitology · X

In comatose survivors of cardiac arrest: targeting a MAP of 77 mmHg vs 63 mmHg https://t.co/eaT6vXedtq & restrictive vs liberal oxygenation strategy (Pao2 9-10 kPa (68-75 mmHg) vs 13-14 kPa (98-105 mmHg) https://t.co/FM5nAVvFXJ did not change death or severe disability https://t.co/92AQKoxr92

Oct 22, 2022 · 15 likes · 8 shares · 8,129 followers View post →
Biomedical Research
@BiomedicalRese1 · X

Oxygen Targets in Comatose Survivors of #Cardiac Arrest For more: https://t.co/uDOkYaf9RA

Oct 21, 2022 · 145 followers View post →
通りすがりの麻酔科医
@torisugari_anes · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/ycxBNu42Au OHCAの昏睡患者に対する目標PaO2が制限群(68-75mmHg)と通常群(98-105)で死亡or神経学低予後が変わるかを調べたRCT 結果は、アウトカムの発生に差はなかった(32.0vs33.9%;HR:0.95[0.75-1.21]) #当麻_呼吸

Oct 20, 2022 · 2,076 followers View post →
Emergency -- Help Them
@emergencysewa · X

RT @armyemdoc:

Oct 20, 2022 · 1 share · 1,152 followers View post →
armyemdoc
@armyemdoc · X

Oct 20, 2022 · 1 like · 1 share · 4,647 followers View post →
KEN
@hch_resident · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/K429Ct8atE

Oct 20, 2022 · 82 followers View post →
Ayman Soubani, MD
@PagingDrAyman · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest: Targeting a PaO2 68-75 mm Hg or 98-105 mm Hg) resulted in a similar incidence of death or severe disability or coma See video link below #MedTwitter #meded #pccmtwitter https://t.co/o3l1qLvxtE https://t.co/JzcvBZX3sL

Oct 20, 2022 · 1 like · 156 followers View post →
@SoMe4MV
@some4mv · X

RT @ventilacionmeca: Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM #SoMe4MV Objetivo de oxigenoterapia en VM liberal o restrictivo no produce cambio significativo en los resultados. https://t.co/vnkYTdXYA0

Oct 20, 2022 · 6,303 followers View post →
Juan AA
@jjabnt · X

RT @ventilacionmeca: Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM #SoMe4MV Objetivo de oxigenoterapia en VM liberal o re…

Oct 20, 2022 · 2 shares · 27 followers View post →
Fede Gordo-Vidal
@ventilacionmeca · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM #SoMe4MV Objetivo de oxigenoterapia en VM liberal o restrictivo no produce cambio significativo en los resultados. https://t.co/iOaBkqnwlm

Oct 20, 2022 · 7 likes · 2 shares · 24,736 followers View post →
J M Antolinez-Motta
@DrAntolinez · X

RT @medpedshosp: Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/xvGMhFQ26C

Oct 19, 2022 · 1 share · 1,068 followers View post →
Med Peds Hospitalist
@medpedshosp · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/xvGMhFQ26C

Oct 19, 2022 · 2 likes · 1 share · 14,320 followers View post →
ふろりあん
@ems4jhondo · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/a2awKcFUih

Oct 19, 2022 · 1,072 followers View post →
Melissa Bregger, MD, FACP
@MelBreggs · X

4a/ Questions 4: Do aggressive vs liberal MAP or PaO2 targets impact outcomes following out-of-hospital cardiac arrest? Trial to answer this: BOX Trial https://t.co/B5HHgqOY5l https://t.co/j4G5CZnVgv

Oct 19, 2022 · 1,706 followers View post →
Konstantin Krychtiuk
@krychtiukmd · X

RT @tscquizzato: #BOX_trial: WHICH OXYGEN TARGET IN RESUSCITATED OHCA?

Oct 15, 2022 · 33 shares · 6,287 followers View post →
NYULangonePCCSM
@NYULangonePCCSM · X

Last week we had an excellent journal club on #cardiacarrest! check out what our fellows are reading from @NEJM

Oct 14, 2022 · 2 likes · 1 share · 2,371 followers View post →
Shawn Brast, MSN, RN, CHPN, NRP
@shawnbrast · X

My how the research keeps changing! Hi or low PaO2 targets post arrest- “not” as important! Oxygen Targets in Comatose Survivors of Cardiac Arrest. N Engl J Med. 2022 Aug 27. doi: 10.1056/NEJMoa2208686

Oct 13, 2022 · 92 followers View post →
Martin Frydland, MD, PhD
@joyland2704 · X

RT @MananPareekMD: The mini #ESCcongress continues - what’s in the BOX? @cardiac_group @RigsHeart https://t.co/s31TNTVEs2 https://t.co/n…

Sep 20, 2022 · 2 shares · 642 followers View post →
Johannes Grand
@JohannesGrand · X

RT @MananPareekMD: The mini #ESCcongress continues - what’s in the BOX? @cardiac_group @RigsHeart https://t.co/s31TNTVEs2 https://t.co/n…

Sep 20, 2022 · 2 shares · 924 followers View post →
Manan Pareek, MD, MSc, PhD, FAHA, FESC
@MananPareekMD · X

The mini #ESCcongress continues - what’s in the BOX? @cardiac_group @RigsHeart https://t.co/s31TNTVEs2 https://t.co/nX7nybhmHE https://t.co/tT3SNUNBGG

Sep 20, 2022 · 20 likes · 2 shares · 956 followers View post →
Hamzeh Alshahwan
@AlshahwanHamzeh · X

RT @japacademy: #JAPACADEMY would like to invite you to this interactive journal club presented by #JAPACADEMY expert Dr.Tarek Gharaibeh ab…

Sep 16, 2022 · 3 shares · 51 followers View post →
Awni Shahait
@AShahait · X

RT @japacademy: #JAPACADEMY would like to invite you to this interactive journal club presented by #JAPACADEMY expert Dr.Tarek Gharaibeh ab…

Sep 16, 2022 · 3 shares · 555 followers View post →
Bashar Alzghoul
@BNZghoul · X

RT @japacademy: #JAPACADEMY would like to invite you to this interactive journal club presented by #JAPACADEMY expert Dr.Tarek Gharaibeh ab…

Sep 16, 2022 · 3 shares · 264 followers View post →
JAP Academy (JAPA) Journal
@japacademy · X

#JAPACADEMY would like to invite you to this interactive journal club presented by #JAPACADEMY expert Dr.Tarek Gharaibeh about Oxygen Targets in Cardiac Arrest Survivors..be there! #MDTwitter #CriticalCare https://t.co/9PCmzv2A8I https://t.co/m0l7IWO44t

Sep 16, 2022 · 4 likes · 3 shares · 742 followers View post →
Societat Catalana de Cardiologia
@catcardio · X

...ni en el percentatge de pacients amb estat cerebral a l'alta molt desfavorable (*CPC 3-4). Els resultats han estat publicats en la revista NEJM. Seguim en la cerca del Sant Greal en aquests pacients Consulteu els articles:

Sep 9, 2022 · 1 like · 4,116 followers View post →
Muhammad Hassan Jan
@hassanjan01 · X

Targeting of a restrictive or liberal oxygenation strategy in comatose patients after resuscitation for cardiac arrest resulted in a similar incidence of death or severe disability or coma. https://t.co/foQDdyAkt8

Sep 8, 2022 · 1 like · 672 followers View post →
Carmelo Espinosa M.D.
@carmelografo · X

RT @ventilacionmeca: 1.- En pacientes en Coma tras PCR no hay diferencia en el pronóstico con objetivo de PaO2 entre 68 y 105 mm de Hg).…

Sep 7, 2022 · 1 share · 631 followers View post →
Prof Daryl Jones
@jones_daza · X

RT @neil_orford: NEJM https://t.co/KWOs9SrWwK Restrictive (PaO2 68-75 mmHg) vs liberal (PaO2 98-105 mmHg) oxygenation target in comatose su…

Sep 7, 2022 · 1 share · 1,045 followers View post →
Fede Gordo-Vidal
@ventilacionmeca · X

1.- En pacientes en Coma tras PCR no hay diferencia en el pronóstico con objetivo de PaO2 entre 68 y 105 mm de Hg). Oxygen Targets in Comatose Survivors of Cardiac Arrest https://t.co/dHCulioJk0

Sep 7, 2022 · 6 likes · 1 share · 24,736 followers View post →
Neil Orford
@neil_orford · X

NEJM https://t.co/KWOs9SrWwK Restrictive (PaO2 68-75 mmHg) vs liberal (PaO2 98-105 mmHg) oxygenation target in comatose survivors OHCA requiring MV no diff 90-d death / severe disability (32 vs 34%, p=0.69) https://t.co/qdjYzIVCoE

Sep 6, 2022 · 2 likes · 1 share · 905 followers View post →
Kasper Kyhl
@Kyhl_K · X

RT @cardio_dk: I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #…

Sep 5, 2022 · 5 shares · 201 followers View post →
Manan Pareek, MD, MSc, PhD, FAHA, FESC
@MananPareekMD · X

RT @cardio_dk: I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #…

Sep 5, 2022 · 5 shares · 956 followers View post →
Johannes Grand
@JohannesGrand · X

RT @cardio_dk: I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #…

Sep 5, 2022 · 5 shares · 924 followers View post →
Jannik Pallisgaard
@Pallisgaard_MD · X

RT @cardio_dk: I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #…

Sep 5, 2022 · 5 shares · 837 followers View post →
Martin Frydland, MD, PhD
@joyland2704 · X

RT @cardio_dk: I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #…

Sep 5, 2022 · 5 shares · 642 followers View post →
Dansk Cardiologisk Selskab (DCS)
@cardio_dk · X

I denne video gennemgår @JohannesGrand de akut-cardiologiske studier, som han synes var de mest interessante til dette års #ESCCongress ➡BOX blood pressure: https://t.co/keXiiKa6tu ➡BOX oxygen: https://t.co/MDbsWDtcCz ➡ADVOR: https://t.co/9iOlvxImaj #DCSESC2022 #dkforsk https://t.co/Adq1Jmo2A5

Sep 5, 2022 · 24 likes · 5 shares · 747 followers View post →
tagacalubian
@tagacalubian · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Sep 3, 2022 · 23 shares · 54 followers View post →
Professor M Z Khalil
@mzkhalil · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM No difference between target restrictive or liberal oxygenation https://t.co/TBN3eKisTn https://t.co/fi0pZkLzg5

Sep 2, 2022 · 2,865 followers View post →
そろそろやるか医
@emephysimed99 · X

RT @FlightDocKosuke: 院外CPA蘇生後(昏睡)の酸素化目標についてのデンマークのRCT. 789名をPaO2:68-75mmHgの制限群,PaO2:98-105mmHg のリベラル群に割付. 神経予後は両群で有意差無し. 蘇生後の酸素目標はやや低めが良いかも…

Sep 2, 2022 · 1 share · 145 followers View post →
こーすけ@救急医
@FlightDocKosuke · X

院外CPA蘇生後(昏睡)の酸素化目標についてのデンマークのRCT. 789名をPaO2:68-75mmHgの制限群,PaO2:98-105mmHg のリベラル群に割付. 神経予後は両群で有意差無し. 蘇生後の酸素目標はやや低めが良いかもという話が以前ありましたが…結局中庸に落ち着いていくのかもですね. https://t.co/lNrNybNUkY

Sep 2, 2022 · 22 likes · 1 share · 3,870 followers View post →
Michael Buratovich
@MichaelBuratovi · X

"Restrictive oxygen target of 68 to 75 mm Hg is a reasonable target range for the majority of comatose patients resuscitated after OHCA." Oxygen Targets in Comatose Survivors of Cardiac Arrest | comment: Benjamin Morgan Scirica MD https://t.co/eGkmqi7dED via @practiceupdate

Sep 1, 2022 · 1,178 followers View post →
ALEXANDRU MISCHIE
@ALEX_MISCHIE · X

Restrictive oxygen target of a partial pressure of arterial oxygen (Pao2) of 9 to 10 kPa (68 to 75 mm Hg) = Liberal oxygen target of a Pao2 of 13 to 14 kPa (98 to 105 mm Hg) Oxygen Targets in Comatose Survivors of Cardiac Arrest https://t.co/mVqpzYVOIZ

Sep 1, 2022 · 10,251 followers View post →
Cardiology
@PracUpCardio · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest https://t.co/GIGm5tkjGc #cardiology

Sep 1, 2022 · 879 followers View post →
Mehmet Arif Mirasoğlu
@Mehmet_1326 · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/59Df8C6Pkm

Sep 1, 2022 · 959 followers View post →
Youcef Azeli
@YoucefAzeli · X

RT @tscquizzato: #BOX_trial: WHICH OXYGEN TARGET IN RESUSCITATED OHCA?

Aug 31, 2022 · 33 shares · 443 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @tscquizzato: #BOX_trial: WHICH OXYGEN TARGET IN RESUSCITATED OHCA?

Aug 31, 2022 · 33 shares · 6,933 followers View post →
Oren Friedman
@OrenFriedman · X

RT @NickJohnsonMD: Reading in detail and pondering the recent, impressive #BOX trial. One takeaway is that both O2 arms remained in what mo…

Aug 30, 2022 · 7 shares · 1,981 followers View post →
Em Em
@emem_omom · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 98 followers View post →
David Carlbom
@CarlbomMD · X

RT @NickJohnsonMD: Reading in detail and pondering the recent, impressive #BOX trial. One takeaway is that both O2 arms remained in what mo…

Aug 30, 2022 · 7 shares · 1,848 followers View post →
Erwin Téllez MD-Interventional Cardiologist
@erwintellez · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 493 followers View post →
色々自粛中(ガラス細工の様な繊細なハートを持つ貴公子
@ECGEPSCADEVICE · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 9,436 followers View post →
Dr Linda Dykes has moved to Bluesky
@DrLindaDykes · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 31,907 followers View post →
Rajinder
@Rajinder · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 767 followers View post →
د . احمد سمان
@Ahmed43101178 · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 6,406 followers View post →
Simran Ghag
@Simranghag_ · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 210 followers View post →
Jonny Wilkinson
@Wilkinsonjonny · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 13,583 followers View post →
Abhishek
@aksrulz13 · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 636 followers View post →
BRAND KHAN
@ShujathUllakhan · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 1,790 followers View post →
Toniya Singh MD FACC
@DrToniyaSingh · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 30, 2022 · 23 shares · 15,865 followers View post →
Dr Raul Hera Jimenez
@rhj_74 · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 701 followers View post →
Dr.J
@gamalkhaled11 · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 379 followers View post →
Cindy Hsu
@CHsu1012 · X

RT @NickJohnsonMD: Reading in detail and pondering the recent, impressive #BOX trial. One takeaway is that both O2 arms remained in what mo…

Aug 29, 2022 · 7 shares · 1,449 followers View post →
Dr Gustavo Leónidas Vera Janavel, MD PhD, MTSAC
@gustavoleonidas · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 1,257 followers View post →
Dr Aidan Baron
@Aidan_Baron · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 16,100 followers View post →
Linda
@wordfinga · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 4,571 followers View post →
CardioAcademic
@CardioAcademic · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 3,223 followers View post →
Abdulrahman Aldiri, MD..د.عبدالرحمن الديري
@Dr_aldiri1 · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 276 followers View post →
Dahoumane Zahra Anais, MD
@anais_dahoumane · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 1,057 followers View post →
David Hall
@icu_dave · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 1,307 followers View post →
PulsePilot
@Pulse1Pilot · X

RT @sarahhudsonuk: 7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictiv…

Aug 29, 2022 · 23 shares · 5,092 followers View post →
Sarah Hudson
@sarahhudsonuk · X

7) There is no difference in rates of death or severe disability/coma between OOHCA pts on ICU treated with a restrictive (target PaO2 9-10kPa) or liberal (Pa02 13-14kPa) oxygen strategy during mechanical ventilation. Evidence: BOX https://t.co/vGfP94gbrc #ESCCongress https://t.co/rvC565HEo8

Aug 29, 2022 · 105 likes · 23 shares · 8,041 followers View post →
Madiha Syed
@madihasyed85 · X

RT @SCCM_Anesth: Restrictive oxygen strategy (PaO2 68-75) does not cause harm versus a liberal (PaO2 98-105) strategy in out-of-hospital ca…

Aug 29, 2022 · 1 share · 229 followers View post →
SCCM Anesthesiology Section
@SCCM_Anesth · X

Restrictive oxygen strategy (PaO2 68-75) does not cause harm versus a liberal (PaO2 98-105) strategy in out-of-hospital cardiac arrest. Read more @NEJM https://t.co/Jz1z7fZ52h

Aug 29, 2022 · 2 likes · 1 share · 908 followers View post →
Cody Cunningham, MD, PhD
@CunninghamResus · X

RT @NickJohnsonMD: Reading in detail and pondering the recent, impressive #BOX trial. One takeaway is that both O2 arms remained in what mo…

Aug 29, 2022 · 7 shares · 403 followers View post →
Erik Rafflenbeul
@KardiologieHH · X

2.4/ #BOX - Oxygen therapy in comatose OHCA patients

Aug 29, 2022 · 11 likes · 1 share · 8,772 followers View post →
@load-depentent.bsky.social
@load_dependent · X

RT @NickJohnsonMD: Reading in detail and pondering the recent, impressive #BOX trial. One takeaway is that both O2 arms remained in what mo…

Aug 29, 2022 · 7 shares · 3,895 followers View post →
Tommaso Scquizzato, MD
@tscquizzato · X

RT @NickJohnsonMD: Reading in detail and pondering the recent, impressive #BOX trial. One takeaway is that both O2 arms remained in what mo…

Aug 29, 2022 · 7 shares · 5,154 followers View post →
Nick Johnson
@NickJohnsonMD · X

Reading in detail and pondering the recent, impressive #BOX trial. One takeaway is that both O2 arms remained in what most would consider normal range. https://t.co/uLeMlMdF3N 1/

Aug 29, 2022 · 22 likes · 7 shares · 6,542 followers View post →
Albert Chan
@gaseousXchange · X

RT @DogICUma: This is a must-read ICU trial https://t.co/cLunhuYrGR

Aug 28, 2022 · 11 shares · 642 followers View post →
Impack
@ImpackCPR · X

RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)

Aug 28, 2022 · 28 shares · 8 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)

Aug 28, 2022 · 28 shares · 6,933 followers View post →
Sebastián Vásquez-García
@Sebastian0329 · X

RT @csmfisher: Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/t2lGbxaqUf

Aug 28, 2022 · 2 shares · 369 followers View post →
Mateusz Zawadka
@m_zawadka · X

RT @JacekGorka: Badanie BOX, którego wyniki opublikowano w @NEJM próbowało odpowiedzieć na pytania o cele terapeutyczne - MAP, pO2 u pacjen…

Aug 28, 2022 · 2 shares · 1,522 followers View post →
Pierce Geoghegan
@geoghep · X

RT @PBSherren: Two important papers for the management of comatose OOHCA pts from the #esccongress2022. In this large RCT, with 2x2 factori…

Aug 28, 2022 · 3 shares · 418 followers View post →
Jakub Fronczek, MD, PhD
@JFronczekMD · X

RT @JacekGorka: Badanie BOX, którego wyniki opublikowano w @NEJM próbowało odpowiedzieć na pytania o cele terapeutyczne - MAP, pO2 u pacjen…

Aug 28, 2022 · 2 shares · 477 followers View post →
Jacek Gorka
@JacekGorka · X

Badanie BOX, którego wyniki opublikowano w @NEJM próbowało odpowiedzieć na pytania o cele terapeutyczne - MAP, pO2 u pacjentów po zatrzymaniu krążenia. Czy mamy kolejne dowody na LESS IS MORE? https://t.co/RvXT2IXc48, https://t.co/HPH8ggrgOq

Aug 28, 2022 · 1 like · 2 shares · 3,276 followers View post →
Solo
@mingzibuganshuo · X

RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)

Aug 28, 2022 · 28 shares · 4 followers View post →
Ricardo Turon Costa
@ricoturon · X

RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)

Aug 28, 2022 · 28 shares · 75 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @cardiac_group: https://t.co/O0uagsB6FE

Aug 28, 2022 · 1 share · 6,933 followers View post →
Leonardo Seoane
@leonardo_seoane · X

RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)

Aug 28, 2022 · 28 shares · 4,325 followers View post →
Antonella degani
@Antonelladegan3 · X

RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)

Aug 28, 2022 · 28 shares · 766 followers View post →
Segun Olusanya (He/Him) iceman_ex@critcare.social
@iceman_ex · X

RT @FOAMecmo: Blood-Pressure & O2 targets in comatose pts resuscitated after #OHCA double-blind RCT (2-by-2 design)

Aug 28, 2022 · 28 shares · 19,686 followers View post →
#intensivistadeguardia
@intensivoonfire · X

RT @DogICUma: This is a must-read ICU trial https://t.co/cLunhuYrGR

Aug 28, 2022 · 11 shares · 5,901 followers View post →
J M
@javimen_f · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/YxZDw249Mw

Aug 28, 2022 · 1,061 followers View post →
Jacques Berré
@JackBerre · X

RT @fabio_taccone: Oxygen Targets in Comatose Survivors of Cardiac Arrest - PubMed https://t.co/izifunQANp

Aug 28, 2022 · 4 shares · 28 followers View post →
Chiara Robba
@chiara_robba · X

RT @csmfisher: Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/t2lGbxaqUf

Aug 28, 2022 · 2 shares · 2,267 followers View post →
Neuro Criticos
@neurointensivos · X

RT @fabio_taccone: Oxygen Targets in Comatose Survivors of Cardiac Arrest - PubMed https://t.co/izifunQANp

Aug 28, 2022 · 4 shares · 2,814 followers View post →
Sung-Min Cho
@csmfisher · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/t2lGbxaqUf

Aug 27, 2022 · 4 likes · 2 shares · 485 followers View post →
Tommaso Scquizzato, MD
@tscquizzato · X

RT @giovannilandoni: #Oxygen Targets in Comatose Survivors of #cardiacarrest At 90 days, death occurred in 113 pts (28.7%) in the restricti…

Aug 27, 2022 · 1 share · 5,154 followers View post →
Romain Pirracchio
@pirracchior · X

RT @fabio_taccone: Oxygen Targets in Comatose Survivors of Cardiac Arrest - PubMed https://t.co/izifunQANp

Aug 27, 2022 · 4 shares · 769 followers View post →
ANARLF
@anarlfasso · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest | NEJM https://t.co/6ZOuvNvqez

Aug 27, 2022 · 3 likes · 1,236 followers View post →
Boback Ziaeian
@boback · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest @nejm #ESC https://t.co/VJh3t3vjWY

Aug 27, 2022 · 3,361 followers View post →
Denise Battaglini
@DeniseBatt25 · X

RT @fabio_taccone: Oxygen Targets in Comatose Survivors of Cardiac Arrest - PubMed https://t.co/izifunQANp

Aug 27, 2022 · 4 shares · 821 followers View post →
Giovanni Landoni, MD
@giovannilandoni · X

#Oxygen Targets in Comatose Survivors of #cardiacarrest At 90 days, death occurred in 113 pts (28.7%) in the restrictive-target group and in 123 (31.1%) in the liberal-target group @NEJM @DogICUma #MegaROX is ongoing and will give us a definitive answer https://t.co/F7GDCoAF9e

Aug 27, 2022 · 5 likes · 1 share · 4,749 followers View post →
Fabio Taccone
@fabio_taccone · X

Oxygen Targets in Comatose Survivors of Cardiac Arrest - PubMed https://t.co/izifunQANp

Aug 27, 2022 · 10 likes · 4 shares · 1,629 followers View post →
cardio (Nijad Bakhshaliyev)
@drnijad · X

Aug 27, 2022 · 925 followers View post →
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Source Reference: Schmidt H, et al "Oxygen targets in comatose survivors of cardiac arrest" N Engl J Med 2022; DOI: 10.1056/NEJMoa2208686.

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