The overall discussions reflect a strong alignment with the article’s conclusions, supported by numerous references to studies from Portugal and other sources about immunity effects, such as '75% protection' and 'substantial protection.' The tone is data-driven and confident, emphasizing research evidence, which underscores the high interest and perceived importance of the findings in shaping our understanding of COVID-19 immunity dynamics.
AgreementStrong agreement
Most comments strongly support the study’s findings on immunity and reinfection, emphasizing evidence from reliable sources like the NEJM, indicating broad consensus.
InterestHigh interest
Discussions are highly relevant to current public health concerns, with many posts citing specific data and studies, demonstrating high engagement with the topic.
EngagementModerate engagement
Numerous posts analyze the data, referencing figures and multiple research articles, reflecting active involvement beyond just passing mentions.
ImpactHigh impact
The emphasis on immunity, reinfection rates, and studies influencing public perceptions highlights high potential influence on understanding COVID-19's trajectory and policy implications.
Abstract in brief
The study examines the likelihood of contracting the BA5 variant of COVID-19 in people who have previously been infected with earlier versions of the virus.
It assesses how previous infections with different SARS-CoV-2 variants influence the risk of getting BA5.
The findings aim to inform public health strategies by understanding immunity and protection levels against new variants like BA5.]
We previously showed that BA.1/BA.2 infection in a highly vaccinated population (Portugal) provides substantial protection against subsequent omicron BA.5 infection: https://t.co/3hbTokMqGd Similar results reported in Denmark and Qatar. What about the waning of protection? 2/12
Jan 6, 2023 · 15 likes · 1 share · 609 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@JReinerMD But the reduction of infection in the masking districts was almost certainly caused by their immune responses to previous infections. We know that from many studies, including this one: https://t.co/cvWmgNSsNG
Nov 10, 2022 · 13 likes · 1 share · 4,008 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@JReinerMD https://t.co/cvWmgNRUY8
Dec 2, 2022 · 8 likes · 4,008 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@maosbot People who have been previously infected and vaccinated are not likely to get long covid. Heck, they're not even likely to get covid. Vaccine + BA.1 or BA.2 is 75% protective against BA.4 or BA.5. https://t.co/cvWmgO9vPG
Oct 25, 2022 · 7 likes · 4,008 followersView post →
This study examines the likelihood of contracting the BA5 variant of COVID-19 in people previously infected with earlier virus versions, providing insights into immunity and informing public health strategies.
This video explores how previous SARS-CoV-2 infections affect susceptibility to the BA5 variant, with a focus on Portugal's experience. It provides insights into natural immunity, transmissibility of variants, and…
@PetersonChris @Lord_grimz @atRachelGilmore Still thinking it's a political issue? No real data, real studies. In fact you were believing fake data from scientist with conflict of interest, and you still do. https://t.co/ryHe8pODth https://t.co/rx6MEMwsEO
@KateBatt1 @LibDemPatrick Wrong. There is a study from Portugal showing that people who had the Wuhan variant had more than 50% immunity against BA.5 more than 2 years later.
https://t.co/kTjRJXSR0B https://t.co/xnN7mJkyDV
@IPizza666 @kevinnbass People do reinfect. But there is massive literature showing that prior infection reduces future infection. https://t.co/cvWmgNRUY8
@AltenbergLee @CollignonPeter Given that people who had the Wuhan strain still had around 50% immunity to BA.4/5, the effect of prior immunity is still relevant.
https://t.co/kTjRJXSR0B
Risk of BA.5 Infection in Persons Exposed to Previous SARSCoV2 Variants: previous SARSCoV-2 infection had protective effect against BA.5 infection;protection was maximal for previous infection with BA.1 or BA.2. https://t.co/PZPIv9x4Fl
Jan 27, 2023 · 2 likes · 34,654 followersView post →
SP
s243a from pearltrees
@s243a_PT · X
@WeeTimorous @0bj3ctivity @Marc_Veld He posted recently the following paper, which suggests that COVID-19 has long lasting hybrid immunity:
https://t.co/L1gOOOZpD0
@EladSharonMD Protection from severe disease was extremely robust among survivors and even against symptomatic infection it did okay:
https://t.co/3evqmQuXJw
Infection should never be used as a public health strategy but immunity from SARS-CoV-2 isn't terrible
Jan 15, 2023 · 1 like · 33,584 followersView post →
AC
Ana Calber
@amcalber · X
RT @BagaiDr: Risk of BA.5 Infection among Persons Exposed to Previous SARSCoV2 Variants: previous SARSCoV2 infection had protective effect…
Jan 15, 2023 · 1 share · 2,264 followersView post →
PB
Prof. Dr. Sanjeev Bagai
@BagaiDr · X
Risk of BA.5 Infection among Persons Exposed to Previous SARSCoV2 Variants: previous SARSCoV2 infection had protective effect against BA.5 infection; this protection was maximal for previous infection with BA.1 or BA.2. https://t.co/PZPIv9x4Fl
Jan 15, 2023 · 4 likes · 1 share · 34,654 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@RichardWWard1 @afugate We no it works for a large majority of people. https://t.co/cvWmgNRUY8
@forlornfollower @PandoWhisperer @stonehenge2500 @friendlycovid19 We also have test survey data from entire nations, like Portugal, showing our massive immune responses. https://t.co/cvWmgNRUY8
Risk of BA.5 Infection among Persons Exposed to Previous SARS-CoV-2 Variants. SARSCoV2 infection had a protective effect against BA.5 infection, and this protection was maximal for previous infection with BA.1 or BA.2. https://t.co/PZPIv9x4Fl
Jan 6, 2023 · 2 likes · 34,654 followersView post →
LG
Luis Graca
@lgraca · X
We previously showed that BA.1/BA.2 infection in a highly vaccinated population (Portugal) provides substantial protection against subsequent omicron BA.5 infection: https://t.co/3hbTokMqGd Similar results reported in Denmark and Qatar. What about the waning of protection? 2/12
Jan 6, 2023 · 15 likes · 1 share · 609 followersView post →
@sue_ecampbell @maosbot The whole comparison is nonsensical. The mechanisms are entirely different. It is in no way similar to airborne HIV. https://t.co/cvWmgO9vPG
@DaveAus23503512 @beantowndancer @JReinerMD https://t.co/cvWmgNSsNG
I don't think your numbers are well out of context of what I'm arguing, it's just different interpretations of subjective terms. Covid isn't over, but it's not pandemic anymore. Immunity matters a lot.
Dec 2, 2022 · 8 likes · 4,008 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@JoshHalpern5 @maosbot We know it is true because >75% of people don't reinfect with later omicrons after an original omicron infection. https://t.co/cvWmgO9vPG
@greg_travis @glirarium There is strong evidence against similar or higher case rates. e.g., https://t.co/cvWmgNRUY8
infection rates reduced by 75% (but perhaps attenuated to 50%) render such an outcome quite unlikely.
@Matt_F_Resende @Pauloc_9 @ElderDias @FanuelArthur @reporterenato Um estudo do New England Journal of Medicine mostrou q quem foi infectado pela ômicron tem uma imunidade natural d 75,3% d eficácia.
Essa eficácia é surpreendente melhor do q alguns imunizantes, já q eles possuem uma baixa eficácia contra a ômicron.
Fonte: https://t.co/CwTuU18BdZ https://t.co/f2gwRfuw2f
@brigitte_d @zwergldoc @agent_alcohol Erstens gibt es diese Daten auch schon, z.B. https://t.co/3xe0YxYV6A
Und zweitens gelten grundsätzliche immunologische Prinzipien bis zum Beweis des Gegenteils auch bei neuen Virus-Varianten
Nov 17, 2022 · 1 like · 4,008 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@helenessex2 @strawthatbroke @GerardoRiordan8 @i_petersen Covid is a much less common cause of mass absences anymore, because of bulk immunity. See this for reference: https://t.co/cvWmgNSsNG
Nov 15, 2022 · 2 likes · 4,008 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@thedougman @friendlycovid19 Bulk nationwide testing data in some nations shows the immunity signal boldly. e.g., https://t.co/cvWmgNSsNG
@fperrywilson @NEJM Effect of prior immunity, e.g., omicron BA.1 and BA.2 infection persists today, reducing infection rates by BA.4 and BA.5. https://t.co/cvWmgNRUY8
The protection is 75%! Earlier variants were also protective against omicron, when mandates started lifting.
@PamR03934520 @AbraarKaran @SafetyFirst____ We know that around 75% of people who had the vaccine and were exposed to either ba1 or ba2 would not even catch ba4 or ba5. https://t.co/cvWmgNSsNG
@ZivaDavid78 @doc_ecmo Das stimmt so nicht, zB:
https://t.co/GwiB1Xg9UA
Oder
https://t.co/wrq0Q7fq2d
uvm.
Aber zugegebenermaßen, bei den immer wieder auftretenden neuen Varianten ist eine Prädiktion, die mehr als ein paar Wochen/ wenige Monate in die Zukunft geht, gewagt.
Nov 12, 2022 · 5 likes · 1 share · 4,162 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@PriscillaRP @BoschEyes @alexmeshkin Lol. There's bulk data that shows immunity is real. https://t.co/cvWmgNSsNG
@BoschEyes @alexmeshkin Better update your priors. https://t.co/cvWmgNSsNG
Nov 11, 2022 · 2 likes · 4,008 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@termined_d @friendlycovid19 It's far more than a dent. https://t.co/cvWmgNSsNG
Also, reduction of deaths after vaccines and prior infections, in subsequent (reduced) infections is enormous. We are far better off then in spring 2020.
@JReinerMD But the reduction of infection in the masking districts was almost certainly caused by their immune responses to previous infections. We know that from many studies, including this one: https://t.co/cvWmgNSsNG
Nov 10, 2022 · 13 likes · 1 share · 4,008 followersView post →
@cookietrousers @AmandaKvalsvig @Klynchstuff1 @emilynz @SabiVM @DrSamiraJeimy @apsmunro I think these statements are still essentially true - that is, hybrid immunity, especially from BA.1 and BA.2, has afforded good protection against infection from BA.4, BA.5, better than that from infection or vax alone. Reinfections occur, but less likely https://t.co/IuGTmLkRIS
Nov 8, 2022 · 1 like · 22,893 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@DavidMasterson6 @friendlycovid19 https://t.co/cvWmgNSsNG
See Figure 1b.
@SuzanneDale88 @Kellymag26 @greg_travis We know that 75% of people who had ba1 and ba2 after vaccination do not become infected when exposed to BA4 or BA5. https://t.co/cvWmgO9vPG
@Musician1980 Schließt an an Daten aus Portugal (da noch kein 2.75) https://t.co/J5sWyYjqAZ
Nov 4, 2022 · 3 likes · 3,093 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@ADS21817949 @v_wie_vendettaa @joaquinlife @lgoshen We know that 75% of people who were vaccinated and then infected by BA.1 or BA.2 don't get infected by BA.4 or BA.5. https://t.co/cvWmgO9vPG
@ADS21817949 @v_wie_vendettaa @joaquinlife @lgoshen We know that 75% of people who were vaccinated and then infected by BA.1 or BA.2 don't get infected by BA.4 or BA.5. https://t.co/cvWmgNRUY8
@ADS21817949 @JReinerMD No. Immune evasive means moderate immune escape. If there was massive immune escape, this could not happen: https://t.co/cvWmgNRUY8
@sioneva @DALupton A few people get 3-4 infections. BUT 75% of people who were vaccinated and infected by BA.1 or BA.2 don't get infected with BA.4 or BA.5. https://t.co/cvWmgNRUY8
Oct 27, 2022 · 1 like · 4,008 followersView post →
Vaccines, boosters, and previous infection reduce reinfection rates by 75%. Counts of long-covid are dominated by mostly minor symptoms, but those who fear it most emphasize unusual extreme cases they think pose them high risk. They don't. https://t.co/cvWmgNSsNG https://t.co/4yLCBIUYGk
@SPWeston @gs2010chat @ChuckWurster People who are constantly exposed aren't constantly infected. Immunity really does matter for this. https://t.co/cvWmgO9vPG
@SPWeston @gs2010chat @ChuckWurster Substantial data backs this up: Infection rates are 75% lower during BA.4 and BA.5 in people previously infected with BA.1 or BA.2 after vaccination. https://t.co/cvWmgNRUY8
@maosbot People who have been previously infected and vaccinated are not likely to get long covid. Heck, they're not even likely to get covid. Vaccine + BA.1 or BA.2 is 75% protective against BA.4 or BA.5. https://t.co/cvWmgO9vPG
Oct 25, 2022 · 7 likes · 4,008 followersView post →
PR
Paul Roundy
@PaulRoundy1 · X
@CT9397 @DGBassani They reduce infection rates by 75%, when combined with a previous omicron infection. https://t.co/cvWmgO9vPG
@coniinthegarden @WalkerBragman It developed continuously over the last 2 years from infections, vaccinations, and exposures. Antibodies, T&B cell, etc. https://t.co/cvWmgNSsNG
Oct 22, 2022 · 2 likes · 4,008 followersView post →
DP
Diderot's Penguin
@DenisDi70745515 · X
@KhrCeleste @mildanalyst "Portugal"
Malato, et al. (2022) ‘Risk of BA.5 Infection among Persons Exposed to Previous SARS-CoV-2 Variants’. _New England Journal of Medicine_ 0, no. 0 (31 August 2022): null. [https://t.co/RrQwiIK54l].
#ETUDESANTEDUSOIR Les personnes vaccinées contre le #COVID19 et contaminées par les 1ers sous-variants #Omicron auraient une protection 4 fois supérieure à celle des personnes vaccinées mais non infectées.
Par @IMMolecular (cohorte portugaise)
Via @NEJM
https://t.co/Vy2J7Klx3X
@EricTopol A study in the New England Journal of Medicine showed that those who were infected by the omicron have a natural immunity of 75.3% effectiveness.
https://t.co/qdQEkrZkdo