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J Am Chem Soc September 2022 PMID 36054724

Detection of Epidermal Growth Factor Receptor Expression in Breast Cancer Cell Lines Using an Ion-Sensitive Field-Effect Transistor in Combination with Enzymatic Chemical Signal Amplification.

Miyuki Tabata, Xinyue Liu, Chattarika Khamhanglit, Sayo Kotaki, Yuji Miyahara

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Mentions

41
Peak: 12 in Sep 2022
across 4 sources since Sep 2022

Extended reach

1,638,395
potential audience

Total likes

44

Video views

321

Mentions per month

Sep 2022 – May 2023

Where it's discussed

  • X / Twitter21 posts
  • News15 articles
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect a balanced view, with posts describing the use of transistors and enzymatic signal amplification for detecting cancer markers, suggesting interest in technological advancements. Words like 'innovative,' 'potential,' and 'future' indicate a positive outlook on the research's significance and possible practical applications.

AgreementModerate agreement

The majority of discussions acknowledge the significance of the research, emphasizing its innovative detection method for cancer markers.

InterestModerate interest

Posts show moderate curiosity, with mentions of potential applications like liquid biopsies and cancer detection, indicating some engagement but not widespread enthusiasm.

EngagementModerate engagement

Discussions reference technical aspects such as enzymatic amplification and transistors, showing a fair level of technical interest and deeper engagement.

ImpactModerate impact

Multiple posts highlight the potential for this technology to impact cancer diagnosis and treatment, suggesting a recognized potential for high influence.

Abstract in brief

  • A novel detection method for EGFR using a cell-based field-effect transistor (FET) combined with enzymatic signal amplification is introduced, focusing on breast cancer cells.
  • Four breast cancer cell lines with varying EGFR expression levels were tested, showing that the FET could accurately measure these levels by utilizing secondary antibodies linked to glucose oxidase.
  • The results matched traditional fluorescence detection methods and suggest that this FET approach could lead to smaller, cost-effective tools for cancer testing in future liquid biopsies.
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Medical Xpress
@medical_xpress · X

Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Oct 31, 2022 · 18 likes · 8 shares · 172,935 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

Detection of EGFR Expression in Breast Cancer Cell Lines Using an Ion-Sensitive Field-Effect Transistor in Combination with Enzymatic Chemical Signal Amplification @TMDUniversity #EGFR #Expression #BreastCancer #Transistor #Signal #Amplification https://t.co/YfN8rCK6tF

Sep 4, 2022 · 9 likes · 1 share · 185,418 followers View post →
Top Science
@isciverse · X

Detection of Epidermal Growth Factor Receptor Expression in Breast Cancer Cell Lines Using an Ion-Sensitive Field-Effect Transistor in Combination with Enzymatic Chemical Signal Amplification @isciverse #Chemistry #ChemTwitter #scicomm #science https://t.co/SFChrbOOmV https://t.co/wEFMvMSTlg

Sep 3, 2022 · 4 likes · 1 share · 40,406 followers View post →
東京医科歯科大学
@tmdu_pr · X

【研究成果発表】 「細胞トランジスタによる細胞膜タンパク質の検出」－リキッドバイオプシーへ適用の可能性－（生体材料工学研究所 特任准教授 田畑 美幸、特任教授 宮原 裕二） プレスリリース https://t.co/MqI9zWtyOa DOI: https://t.co/dYa6gUsLnc ＃東京医科歯科大学 #tmdu https://t.co/7MWvAsczR1

Sep 7, 2022 · 4 likes · 2 shares · 3,520 followers View post →
Extracellular Vesicles & Circulating Nucleic Acids
@VesiclesAcids · X

Sep 6, 2022 · 3 likes · 1 share · 1,781 followers View post →
TMDU - Tokyo Medical and Dental University
@TMDUniversity · X

A new paper by Tabata M, Miyahara Y et al: Detection of epidermal growth factor receptor expression in breast cancer cell lines using an ion-sensitive field effect transistor in combination with enzymatic chemical signal amplification in Journal of the American Chemical Society. https://t.co/aHI1jgOiKk

Sep 7, 2022 · 3 likes · 723 followers View post →

All mentions

TMDU - Tokyo Medical and Dental University
@TMDUniversity · X

New video from "TMDU Research Activities 2022-2023" has been released. “Transistors help identify cancer cell markers” by Yuji Miyahara. Please take a look! YouTube: https://t.co/kG2oDwQUjm HP: https://t.co/wmMidXpTmz #東京医科歯科大学 #tmdu @J_A_C_S https://t.co/qb61BdNGUx

May 9, 2023 · 1 like · 721 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
@np_grwl · X

RT @medical_xpress: Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Nov 9, 2022 · 8 shares · 1,786 followers View post →
Analio Dugarte
@analioj · X

RT @medical_xpress: Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Nov 1, 2022 · 8 shares · 2,189 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

RT @medical_xpress: Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Oct 31, 2022 · 8 shares · 185,418 followers View post →
serrgv
@serrgv · X

RT @medical_xpress: Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Oct 31, 2022 · 8 shares · 148 followers View post →
Medical Xpress
@physorg_health · X

RT @medical_xpress: Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Oct 31, 2022 · 8 shares · 7,109 followers View post →
Science X
@sciencex_com · X

RT @medical_xpress: Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Oct 31, 2022 · 8 shares · 3,530 followers View post →
Phys.org
@physorg_com · X

RT @medical_xpress: Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Oct 31, 2022 · 8 shares · 1,023,938 followers View post →
Medical Xpress
@medical_xpress · X

Transistors help identify #cancer cell markers @J_A_C_S https://t.co/TRAGqXCQxF https://t.co/feU1po0wrJ

Oct 31, 2022 · 18 likes · 8 shares · 172,935 followers View post →
TMDU_生命倫理研究センター
@berc160129 · X

RT @tmdu_pr: 【研究成果発表】 「細胞トランジスタによる細胞膜タンパク質の検出」－リキッドバイオプシーへ適用の可能性－（生体材料工学研究所 特任准教授 田畑 美幸、特任教授 宮原 裕二） プレスリリース https://t.co/MqI9zWtyOa DOI:…

Sep 12, 2022 · 2 shares · 188 followers View post →
info1628MF1319
@info1628MF1319 · X

RT @tmdu_pr: 【研究成果発表】 「細胞トランジスタによる細胞膜タンパク質の検出」－リキッドバイオプシーへ適用の可能性－（生体材料工学研究所 特任准教授 田畑 美幸、特任教授 宮原 裕二） プレスリリース https://t.co/MqI9zWtyOa DOI:…

Sep 7, 2022 · 2 shares · 827 followers View post →
TMDU - Tokyo Medical and Dental University
@TMDUniversity · X

Detection of cell membrane proteins by cell-based field-effect transistor (FET) could lead to the realization of liquid biopsy in the future. HP: https://t.co/wmMidXpTmz DOI: https://t.co/pMY2NTZbXw #東京医科歯科大学 #tmdu @J_A_C_S

Sep 7, 2022 · 2 likes · 1 share · 723 followers View post →
TMDU - Tokyo Medical and Dental University
@TMDUniversity · X

A new paper by Tabata M, Miyahara Y et al: Detection of epidermal growth factor receptor expression in breast cancer cell lines using an ion-sensitive field effect transistor in combination with enzymatic chemical signal amplification in Journal of the American Chemical Society. https://t.co/aHI1jgOiKk

Sep 7, 2022 · 3 likes · 723 followers View post →
東京医科歯科大学
@tmdu_pr · X

【研究成果発表】 「細胞トランジスタによる細胞膜タンパク質の検出」－リキッドバイオプシーへ適用の可能性－（生体材料工学研究所 特任准教授 田畑 美幸、特任教授 宮原 裕二） プレスリリース https://t.co/MqI9zWtyOa DOI: https://t.co/dYa6gUsLnc ＃東京医科歯科大学 #tmdu https://t.co/7MWvAsczR1

Sep 7, 2022 · 4 likes · 2 shares · 3,520 followers View post →
Ace Bryan Sotelo Cabal
@ace_cabal · X

RT @VesiclesAcids:

Sep 6, 2022 · 1 share · 1,133 followers View post →
Extracellular Vesicles & Circulating Nucleic Acids
@VesiclesAcids · X

Sep 6, 2022 · 3 likes · 1 share · 1,781 followers View post →
Naji Ibrahim Jaber
@najijaber7 · X

RT @J_A_C_S: Detection of EGFR Expression in Breast Cancer Cell Lines Using an Ion-Sensitive Field-Effect Transistor in Combination with En…

Sep 4, 2022 · 1 share · 455 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

Detection of EGFR Expression in Breast Cancer Cell Lines Using an Ion-Sensitive Field-Effect Transistor in Combination with Enzymatic Chemical Signal Amplification @TMDUniversity #EGFR #Expression #BreastCancer #Transistor #Signal #Amplification https://t.co/YfN8rCK6tF

Sep 4, 2022 · 9 likes · 1 share · 185,418 followers View post →
ScienceStop
@B0tSci · X

RT @isciverse: Detection of Epidermal Growth Factor Receptor Expression in Breast Cancer Cell Lines Using an Ion-Sensitive Field-Effect Tra…

Sep 3, 2022 · 1 share · 4,080 followers View post →
Top Science
@isciverse · X

Detection of Epidermal Growth Factor Receptor Expression in Breast Cancer Cell Lines Using an Ion-Sensitive Field-Effect Transistor in Combination with Enzymatic Chemical Signal Amplification @isciverse #Chemistry #ChemTwitter #scicomm #science https://t.co/SFChrbOOmV https://t.co/wEFMvMSTlg

Sep 3, 2022 · 4 likes · 1 share · 40,406 followers View post →
Paperbirds_Oncology
@PaperbirdsO · X

New article: Detection of Epidermal Growth Factor Receptor Expression in Breast Cancer Cell Lines Using an Ion-Sensitive Field-Effect Transistor in Combination with Enzymatic Chemical Signal Amplification https://t.co/gVRKpDg3E9 #breastcancer #oncology https://t.co/iGE3moyWTN

Sep 2, 2022 · 892 followers View post →