PubHawk
October 2022 PMID 36137252

Ligand-Enabled C-H Hydroxylation with Aqueous HO at Room Temperature.

Zhen Li, Han Seul Park, Jennifer X Qiao, Kap-Sun Yeung, Jin-Quan Yu

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Mentions

27
Peak: 22 in Sep 2022
across 2 sources since Sep 2022

Extended reach

1,376,665
potential audience

Total likes

1,120

Video views

48,858

Mentions per month

Sep 2022 – Nov 2022

Where it's discussed

  • X / Twitter25 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions repeatedly emphasize the groundbreaking nature of using aqueous hydrogen peroxide at room temperature, often describing it as 'amazing' or 'pioneering.' The tone reflects excitement about its potential to advance sustainable catalysis, with posts mentioning the significance of this methodology for natural product synthesis and industrial processes.

AgreementModerate agreement

Most discussions express positive recognition of the publication, with some calling it significant or 'amazing,' indicating general support.

InterestHigh interest

The posts highlight high enthusiasm for this research, with many emphasizing its novelty and potential, showing strong engagement with the topic.

EngagementModerate engagement

Discussions reference specific aspects of the research, such as reaction conditions and the importance of aqueous hydrogen peroxide, demonstrating moderate to deep engagement.

ImpactHigh impact

Given the focus on green catalysis and room-temperature reactions, many consider this work impactful for sustainable chemistry and future applications.

Abstract in brief

  • The study addresses the need for catalysts that work with green oxidants in Pd(II)-catalyzed C-H activation reactions, focusing on the challenge of using sustainable aqueous hydrogen peroxide.
  • A new bifunctional bidentate carboxyl-pyridone ligand facilitates room-temperature Pd-catalyzed C-H hydroxylation of various benzoic and phenylacetic acids, using hydrogen peroxide as the oxidant.
  • The methodology is scalable, as demonstrated with a significant reaction scale of ibuprofen, and can produce derivatives and complex natural products from the resulting phenol intermediates.
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Top posts

Most liked on X and Bluesky
J. Am. Chem. Soc.
@J_A_C_S · X

Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @YulabJin @scrippsresearch #CHHydroxylation #HydrogenPeroxide #Catalysis https://t.co/bMR2p2Hfft

Sep 23, 2022 · 36 likes · 4 shares · 185,590 followers View post →
Top Science
@isciverse · X

Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm #news #Technology #Tech #NewsBreak #Trending #research #science #AcademicTwitter https://t.co/1dM9nFsDVW https://t.co/WKhPH30hiu

Sep 23, 2022 · 33 likes · 7 shares · 40,416 followers View post →
Chemistry News
@ChemistryNews · X

Just Published: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature https://t.co/l4Mrs8VtXB

Sep 22, 2022 · 23 likes · 1 share · 517,885 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

Check out this video by Prof. J.Q. Yu (Scripps) describing pioneering developments in CH Functionalization which is in JACS https://t.co/yL2ifcT2Db

Sep 29, 2022 · 11 likes · 2 shares · 185,290 followers View post →
Isaac Garcia Bosch
@IsaacGB9 · X

https://t.co/DRqSKWjEwL

Sep 22, 2022 · 11 likes · 1,601 followers View post →
That Chemist
@That_Chemist · X

New Important Papers for the month of October! https://t.co/yJtJJaLoDT

Oct 27, 2022 · 6 likes · 1 share · 6,436 followers View post →

All mentions

Lisan Al-Qaeda
@huahingang · X

Five Important Papers in Organic Synthesis (October 2022) https://t.co/SxKETGJXWc via @YouTube

Nov 3, 2022 · 69 followers View post →
にゅ！
@nyu_alc · X

Five Important Papers in Organic Synthesis (October 2022) https://t.co/10WhUlmoZZ @YouTubeより おべんつよに使えそうな動画を見っけたので視聴してる

Oct 29, 2022 · 5 likes · 903 followers View post →
Collins Ngetich
@CollinsNgetich0 · X

RT @That_Chemist: New Important Papers for the month of October! https://t.co/yJtJJaLoDT

Oct 28, 2022 · 1 share · 821 followers View post →
That Chemist
@That_Chemist · X

New Important Papers for the month of October! https://t.co/yJtJJaLoDT

Oct 27, 2022 · 6 likes · 1 share · 6,436 followers View post →
abelito
@abelegbemhenghe · X

RT @J_A_C_S: Check out this video by Prof. J.Q. Yu (Scripps) describing pioneering developments in CH Functionalization which is in JACS ht…

Sep 29, 2022 · 2 shares · 252 followers View post →
Su Chen
@SuChan32614613 · X

RT @J_A_C_S: Check out this video by Prof. J.Q. Yu (Scripps) describing pioneering developments in CH Functionalization which is in JACS ht…

Sep 29, 2022 · 2 shares · 15 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

Check out this video by Prof. J.Q. Yu (Scripps) describing pioneering developments in CH Functionalization which is in JACS https://t.co/yL2ifcT2Db

Sep 29, 2022 · 11 likes · 2 shares · 185,290 followers View post →
terpene tribe
@TerpeneTribe · X

RT @J_A_C_S: Check out a video by Prof. J.-Q. Yu (Scripps) on new C-H oxidation approach recently published in J. Am. Chem. Soc......the id…

Sep 28, 2022 · 1 share · 5 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

Check out a video by Prof. J.-Q. Yu (Scripps) on new C-H oxidation approach recently published in J. Am. Chem. Soc......the ideal to run reaction! https://t.co/NTFG8jVWI0

Sep 28, 2022 · 4 likes · 1 share · 185,290 followers View post →
Scientific Update
@SciUp · X

Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature https://t.co/wbXc8cpbvy

Sep 27, 2022 · 2,223 followers View post →
Rubén Miguélez
@MorenRmm · X

Amazing!! https://t.co/nQm1xP003x

Sep 24, 2022 · 2 likes · 593 followers View post →
Maurice Médebielle
@FLUORrismo · X

RT @J_A_C_S: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @YulabJin @scrippsresearch #CHHydroxylation #HydrogenPe…

Sep 24, 2022 · 4 shares · 1,381 followers View post →
Khanh M. N. An (光絃之明)
@2xYS_MG_ · X

RT @J_A_C_S: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @YulabJin @scrippsresearch #CHHydroxylation #HydrogenPe…

Sep 23, 2022 · 4 shares · 204 followers View post →
Analio Dugarte
@analioj · X

RT @isciverse: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm…

Sep 23, 2022 · 7 shares · 2,187 followers View post →
Radoslav (Rade) Pavlović
@RadoslavPavlov4 · X

RT @isciverse: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm…

Sep 23, 2022 · 7 shares · 1,978 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

RT @isciverse: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm…

Sep 23, 2022 · 7 shares · 185,590 followers View post →
J. Am. Chem. Soc.
@J_A_C_S · X

Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @YulabJin @scrippsresearch #CHHydroxylation #HydrogenPeroxide #Catalysis https://t.co/bMR2p2Hfft

Sep 23, 2022 · 36 likes · 4 shares · 185,590 followers View post →
Julio Zamora Moreno
@JulioZamoraMor2 · X

RT @isciverse: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm…

Sep 23, 2022 · 7 shares · 44 followers View post →
Arkaitz Correa
@CorreaChemLab · X

RT @ChemistryNews: Just Published: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature https://t.co/l4Mrs8VtXB

Sep 23, 2022 · 1 share · 816 followers View post →
Academic Chatter
@workingbnb · X

RT @isciverse: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm…

Sep 23, 2022 · 7 shares · 3,093 followers View post →
ScienceStop
@B0tSci · X

RT @isciverse: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm…

Sep 23, 2022 · 7 shares · 4,074 followers View post →
Top Science
@isciverse · X

Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature @J_A_C_S @isciverse #Chemistry #ChemTwitter #scicomm #news #Technology #Tech #NewsBreak #Trending #research #science #AcademicTwitter https://t.co/1dM9nFsDVW https://t.co/WKhPH30hiu

Sep 23, 2022 · 33 likes · 7 shares · 40,416 followers View post →
Chemistry News
@ChemistryNews · X

Just Published: Ligand-Enabled C–H Hydroxylation with Aqueous H2O2 at Room Temperature https://t.co/l4Mrs8VtXB

Sep 22, 2022 · 23 likes · 1 share · 517,885 followers View post →
Buddy Soto Cairoli
@SotoCairoli · X

https://t.co/68ksXU7zBt

Sep 22, 2022 · 906 followers View post →
Isaac Garcia Bosch
@IsaacGB9 · X

https://t.co/DRqSKWjEwL

Sep 22, 2022 · 11 likes · 1,601 followers View post →