Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups.

Manuel Mattheisen, Jakob Grove, Thomas D Als, Joanna Martin, Georgios Voloudakis, Sandra Meier, Ditte Demontis, Jaroslav Bendl, Raymond Walters, Caitlin E Carey, Anders Rosengren, Nora I Strom, Mads Engel Hauberg, Biao Zeng, Gabriel Hoffman

October 2022 Nat Genet

Synopsis of Social media discussions

Several discussions emphasize the genetic similarities and differences addressed in the publication, with phrases like 'shared genetics' and 'differentiating loci' reflecting an attempt to interpret complex scientific findings. The tone and choice of words—such as 'pointing to three different subtypes'—indicate curiosity and recognition of the research’s relevance, but the dialogue remains somewhat preliminary and broad, not deeply exploring practical or theoretical implications.

A
Agreement
 Moderate agreement

Most discussions acknowledge the significance of the research, with some posts highlighting its contribution to understanding genetic overlaps between autism and ADHD, exemplified by phrases like 'shared genes' and 'differentiating genetic architecture.'

I
Interest
 Moderate level of interest

The posts demonstrate a moderate level of curiosity, referencing the genetic findings and potential subtypes, indicating genuine interest without overly technical language.

E
Engagement
 Moderate level of engagement

Posts contain references to the study's methods, implications, and potential relevance, such as linking to the publication and discussing genetic subtypes, showing an active but surface-level engagement.

I
Impact
 Neutral impact

Overall, discussions suggest awareness of the study's importance but lack deep analysis or calls to action, implying a neutral perception of its immediate impact.

Social Mentions

YouTube

2 Videos

Facebook

2 Posts

Twitter

30 Posts

Blogs

4 Articles

News

12 Articles

Reddit

2 Posts

Metrics

Video Views

5,330

Total Likes

289

Extended Reach

199,902

Social Features

52

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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September 2, 2025

582 views

  • Neuropediatrics®️
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    Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups https://t.co/Zaj5syeCJ2
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    November 22, 2022

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    November 12, 2022

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    @NTtakes Latest research is pointing to three different subtypes: Autism, ADHD, and AuDHD brains. https://t.co/tmyAj409Qk
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    October 22, 2022

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    @immaqua et al. cited GenomeDK ressources in "Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups" published by Nature Genetics. @jakob_grove @AndersBorglum
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    This was a link to the press release pdf. Here’s a more accessible html version of the same: https://t.co/91T6AOlX48 Here’s a link to the study: ”#Autism and #ADHD share genes”, Nature Genetics (2022). https://t.co/smWYSwjjE2 https://t.co/GYJijtB4v5
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    Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups - Nature || #AutismNews Courtesy of Rick Kirkham The Only In Home Tutor On Oahu Specializing in… https://t.co/bLmnIShnkg
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    @AuDHD_Therapist Now if only Sci-Hub had the linked article 10.1038/s41588-022-01171-3 available.
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    Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups - Nature || #AutismNews Courtesy of Rick Kirkham The Only In Home Tutor On Oahu Specializing in… https://t.co/PCet4CxHxc
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Abstract Synopsis

  • ADHD and autism spectrum disorder (ASD) share significant genetic similarities, with researchers identifying seven shared genetic loci and five that differentiate the two conditions.
  • The differentiating loci show opposite genetic effects in ADHD and ASD and are linked to traits like educational achievement and brain volume, while shared genetics correlate with other psychiatric traits.
  • Individuals with both ADHD and ASD exhibit unique genetic patterns, suggesting that understanding these genetic influences can help clarify the biological underpinnings of each disorder and how they may impact cognitive and psychological traits differently.