Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements: Results From the UK Biobank Resource.
Discussions reflect an overall positive attitude toward the research, with comments praising the significance of CRTAC1 as a biomarker and sharing links to interviews and articles. Interest and engagement are driven by mentions of the study’s methods and potential for early diagnosis, using wording like 'great discussion' and 'study’s first author' to emphasize relevance and credibility.
AgreementModerate agreement
Many discussions highlight the significance of the findings, showing general agreement on the importance of CRTAC1 as a biomarker and its potential clinical advantages.
InterestModerate interest
Participants show moderate curiosity, especially when discussing implications for osteoarthritis diagnosis and treatment, but some comments focus on related topics or general health stories.
EngagementModerate engagement
Posts involve references to new research, interviews with study leaders, and potential clinical impacts, indicating they are engaging with the scientific content at a moderate depth.
ImpactModerate impact
Several discussions point out how these findings could influence future diagnostics and treatments for osteoarthritis, suggesting perceived high potential impact.
Abstract in brief
Plasma levels of Cartilage Acidic Protein 1 (CRTAC1) are strongly associated with prevalent osteoarthritis (OA) and can predict future OA development and progression to joint replacement.
Higher CRTAC1 levels significantly increase the risk of OA in the knee and hip, with those in the highest risk quintile having a 10-fold increased chance of developing OA within 5 years.
The study confirms CRTAC1 as a specific biomarker for OA, and combining it with other proteins like ACAN and NCAN can improve prediction accuracy for OA progression.]
★ Hear our interview with Dr. Chris Whelan, the co-founder and chair of one of the world’s largest scientific studies of blood protein #biomarkers to date: https://t.co/OWSCZp1XMM YouTube: https://t.co/amzYkbT51i
@chrisdwhelan #precisionmedicine #drugdiscovery https://t.co/b9Y9x7aji1
Cancer-specific protein signatures in plasma were discovered using Olink® Explore technology. Tune in to our podcast featuring the study’s first author, @_buenoalvez, to learn more: https://t.co/byQswHcUF0
Video: https://t.co/qssyrKSUTD
#proteomics #biomarkers #cancerresearch https://t.co/X3yrqnJP1H
Aug 30, 2023 · 3 likes · 1 share · 1,765 followersView post →
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ACR_Journals
@ACR_Journals · X
Just accepted in Arthritis & Rheumatology:
The CRTAC1 protein in plasma associates with prevalent osteoarthritis and predicts future risk as well as progression to joint replacements – Results from the UK Biobank resource
https://t.co/sXpY0crHfI
Nov 24, 2022 · 1 like · 1 share · 14,347 followersView post →
TV
Tal Varsano
@varsanot · X
deCODE genetics/Amgen study powered by Olink identifies and validates osteoarthritis (OA) #biomarkers that could facilitate an earlier #diagnosis of OA.
Arthrits & Rheumatology, Oct 2022
"The CRTAC1 protein in #plasma associates…https://t.co/WVTLpcT4QV https://t.co/zfTd4fyHlM
New Full Length from Arthritis & Rheumatology:
Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements: Results From the UK Biobank Resource
https://t.co/LH5yTkp3Qp
#OpenAccess
This episode discusses a study on next-generation pancancer blood proteome profiling using proximity extension assay, highlighting its potential for cancer diagnostics and monitoring, with insights from experts at…
Plasma levels of Cartilage Acidic Protein 1 are strongly associated with osteoarthritis and can predict disease development and progression to joint replacement, providing a potential biomarker for early detection and…
Cancer-specific protein signatures in plasma were discovered using Olink® Explore technology. Tune in to our podcast featuring the study’s first author, @_buenoalvez, to learn more: https://t.co/byQswHcUF0
Video: https://t.co/qssyrKSUTD
#proteomics #biomarkers #cancerresearch https://t.co/X3yrqnJP1H
Aug 30, 2023 · 3 likes · 1 share · 1,765 followersView post →
JS
Jochen Schwenk
@jochwenk · X
RT @OlinkProteomics: ★ Hear our interview with Dr. Chris Whelan, the co-founder and chair of one of the world’s largest scientific studies…
★ Hear our interview with Dr. Chris Whelan, the co-founder and chair of one of the world’s largest scientific studies of blood protein #biomarkers to date: https://t.co/OWSCZp1XMM YouTube: https://t.co/amzYkbT51i
@chrisdwhelan #precisionmedicine #drugdiscovery https://t.co/b9Y9x7aji1
New Full Length from Arthritis & Rheumatology:
Cartilage Acidic Protein 1 in Plasma Associates With Prevalent Osteoarthritis and Predicts Future Risk as Well as Progression to Joint Replacements: Results From the UK Biobank Resource
https://t.co/LH5yTkp3Qp
#OpenAccess
Just accepted in Arthritis & Rheumatology:
The CRTAC1 protein in plasma associates with prevalent osteoarthritis and predicts future risk as well as progression to joint replacements – Results from the UK Biobank resource
https://t.co/sXpY0crHfI
Nov 24, 2022 · 1 like · 1 share · 14,347 followersView post →
TV
Tal Varsano
@varsanot · X
deCODE genetics/Amgen study powered by Olink identifies and validates osteoarthritis (OA) #biomarkers that could facilitate an earlier #diagnosis of OA.
Arthrits & Rheumatology, Oct 2022
"The CRTAC1 protein in #plasma associates…https://t.co/WVTLpcT4QV https://t.co/zfTd4fyHlM
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