The neural basis of psychedelic action.

Alex C Kwan, David E Olson, Katrin H Preller, Bryan L Roth

November 2022 Nat Neurosci

Synopsis of Social media discussions

Several discussions reference specific sections of the article, such as emphasizing the integrative perspective on the neural mechanisms of psychedelics and mentioning future research directions. For instance, comments highlight the research's attempt to synthesize knowledge across various scientific levels and express excitement about potential therapeutic effects, using phrases like 'looking ahead' and 'enduring effects' to convey enthusiasm and optimism about the future of psychedelic research.

A
Agreement
 Moderate agreement

Most discussions reflect a supportive stance on the findings presented in the publication, indicating general alignment with the research conclusions.

I
Interest
 High level of interest

Posts exhibit a strong curiosity regarding the content and implications of the study, suggesting that users find the topic very engaging.

E
Engagement
 Moderate level of engagement

While some posts share summaries or headlines, others delve into specific aspects of the work, revealing a moderate depth of engagement with the research.

I
Impact
 High level of impact

Many contributors acknowledge the potential for significant influence on future research and therapeutic practices, suggesting a belief in the article's impact.

Social Mentions

YouTube

2 Videos

Bluesky

1 Posts

Facebook

6 Posts

Twitter

83 Posts

Blogs

6 Articles

News

45 Articles

Reddit

2 Posts

Metrics

Video Views

5,024

Total Likes

414

Extended Reach

1,400,012

Social Features

145

Timeline: Posts about article

Top Social Media Posts

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  • EurekaMag
    @EurekaMag (Twitter)

    The neural basis of psychedelic action https://t.co/2xcWPURcmP
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    August 20, 2025

  • Harris Sarah
    @One07B (Twitter)

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    April 27, 2024

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  • Dr Ramdas Pananthattil
    @PananthattilR (Twitter)

    RT @NatureNeuro: Review on the neural basis of #psychedelic action from Alex Kwan, David Olson, Katrin Preller & Bryan Roth @kwanalexc @D…
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    March 23, 2023

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  • thelifemedical
    @thelifemedical (Twitter)

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    February 9, 2023

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    @ViewsOnDrugsBot (Twitter)

    RT @ViewsOnDrugsBot: The neural basis of #psychedelic action 1/5 https://t.co/JBVPgFJlJZ
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    February 7, 2023

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    December 8, 2022

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    @ShardayCM (Twitter)

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    @Ulises_MH10 (Twitter)

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    November 12, 2022

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  • Javier Morodo
    @JavierMtzMorodo (Twitter)

    "The Neural Basis of Psychedelic Action", publicado en Nature Neuroscience, explica la neurobiología básica de las drogas psicodélicas a nivel químico, molecular, neuronal y de red. https://t.co/6ufWCt5RuM https://t.co/JBl15jGyJu
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    38

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    @Imperial_PRG (Twitter)

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    @Roswitamind (Twitter)

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    @leechbrain (Twitter)

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    November 10, 2022

    38

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    @royesal (Twitter)

    RT @LeorRoseman: 1/18 THREAD. New paper by @marcoaqil and me. We challenge most theories regarding the neural basis of psychedelic action b…
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    November 10, 2022

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  • Views on Drugs
    @ViewsOnDrugsBot (Twitter)

    RT @LeorRoseman: 1/18 THREAD. New paper by @marcoaqil and me. We challenge most theories regarding the neural basis of psychedelic action b…
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    November 10, 2022

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    @NoletLaure (Twitter)

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    November 10, 2022

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  • Franklin King MD
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    RT @LeorRoseman: 1/18 THREAD. New paper by @marcoaqil and me. We challenge most theories regarding the neural basis of psychedelic action b…
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  • Leor Roseman
    @LeorRoseman (Twitter)

    1/18 THREAD. New paper by @marcoaqil and me. We challenge most theories regarding the neural basis of psychedelic action by claiming something quite simple: psychedelics are visionary and most theories don’t take this specific sensory domain into account. https://t.co/jgRQLal9BG
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    November 10, 2022

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    @BellevueDoc (Twitter)

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    .@kwanalexc et al review the neuroscience of psychedelics It covers the chemistry, receptors and molecular signalling of psychedelics, as well as recent insights into how psychedelics modulate neurons and neural circuits https://t.co/jWhKbLHlW0 2/9
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    October 27, 2022

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  • Blossom
    @blossomact (Twitter)

    Especially interesting is the 'looking ahead' section Research in the next 10y will focus on whether the subjective experience can be separable from therapeutic effects & how receptors & signalling pathways vary across cell types & neural circuits https://t.co/4G1ZqHoc1O 3/9
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    @CJHatzipantelis (Twitter)

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    @coristus (Twitter)

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    @NatureNeuro (Twitter)

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    @seeingwithsound.bsky.social (Bluesky)

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  • The vOICe vision BCI
    @seeingwithsound (Twitter)

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Abstract Synopsis

  • Psychedelics are compounds that activate serotonin 2A receptors, causing significant changes in how people perceive, think, and feel.
  • The review explores the chemical properties of various psychoactive substances and how they interact with the nervous system, focusing on serotonin receptors and their signaling pathways for drug development.
  • It also examines how psychedelics affect brain activity and structure, supported by neuroimaging studies that reveal their influence on brain networks, particularly in relation to behavior.