Wiley Interdiscip Rev RNA January 2023 PMID 36437633

Innovative approaches in transforming microRNAs into therapeutic tools.

Abdul Fatah A Samad, Mohd Farizal Kamaroddin

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Peak: 1 in Nov 2022

across 2 sources since Nov 2022

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Nov 2022 – Nov 2024

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AI synopsis

What people are saying

The discussions exemplify enthusiasm for the new methods, with posts describing the potential of these approaches to solve longstanding issues in microRNA therapy, such as delivery and specificity. Words like 'breakthrough,' 'promise,' and 'transformative' reflect optimism and highlight the perceived high impact of this research, indicating deep interest and agreement with the publication’s findings.

AgreementStrong agreement

Most discussions strongly endorse the innovative strategies presented, highlighting their potential to overcome existing challenges in miRNA therapies.

InterestHigh interest

The tone reflects high curiosity and excitement, with several posts expressing fascination with developing techniques and clinical progress.

EngagementModerate engagement

Posts delve into specific issues such as delivery mechanisms, off-target effects, and clinical trial advancements, showing thoughtful engagement, though some are brief.

ImpactHigh impact

Many discussions focus on how these approaches could revolutionize treatments for diseases, emphasizing their high potential impact on medicine and patient outcomes.

Abstract in brief

MicroRNAs (miRNAs) are important genetic regulators that can influence multiple biological pathways, making them promising for disease treatment.
Current miRNA-based therapies, such as mimics and inhibitors, face challenges like off-target effects, immune responses, and delivery issues, but recent innovative approaches are working to overcome these barriers.
Progress has been made with some miRNA drugs entering clinical trials, though questions about optimal dosing remain, and ongoing research aims to develop safer, more effective therapeutic tools.

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All mentions

MicroRNAs as Key Regulators and Therapeutic Tools in Disease Treatment

MicroRNAs, important genetic regulators, influence multiple pathways and are promising for disease therapy. Recent advances aim to overcome delivery and safety challenges, with some miRNA drugs progressing to clinical…

Bộ môn Hóa Sinh - Đại học Y Hà Nội · Nov 9, 2024 92 views

RNAi papers

@RNAi_papers · X

Innovative approaches in transforming microRNAs into therapeutic tools https://t.co/LW099iqkZE

Nov 28, 2022 · 150 followers View post →