The collective reactions strongly affirm that Denisovan introgression has notably influenced modern Papuans' immune systems, with phrases like 'shaped the immune system' and 'advantage for protection against pathogens' illustrating support. The tone is generally positive and alert to the significance of ancient DNA research, emphasizing its evolutionary and health implications while few posts delve into technical details, contributing to a high perceived impact.
AgreementStrong agreement
Many discussions emphasize the significance of Denisovan DNA in shaping Papuans' immune systems, showing strong support for the findings.
InterestModerate interest
Posts demonstrate moderate interest, highlighting the potential advantages of Denisovan introgression for immunity, but without deep scientific analysis.
EngagementModerate engagement
Most discussions reference the research directly or share it, indicating curiosity, though few go into detailed critique or methodological analysis.
ImpactHigh impact
The widespread sharing and emphasis on the discovery's implications reflect recognition of its high impact on understanding human evolution and health.
Abstract in brief
Modern humans have mixed genetically with archaic hominins, particularly Denisovans, contributing up to 5% of Papuans' genome from these ancient relatives.
Researchers examined 56 Papuan genomes to understand the effects of Denisovan and Neanderthal genetic variants in various cell types and functional elements, finding that archaic alleles are enriched in areas related to gene regulation and immune functions.
They identified thousands of Denisovan and Neanderthal variants that could influence gene activity, validating the functional impact of some variants through experiments, which suggests archaic DNA plays a significant role in shaping modern human genetics and phenotypic traits, especially in non-African populations.
"Modern humans have admixed with multiple archaic hominins." Their immune systems may have picked up some survival tricks when they mated with the mysterious Denisovans.
#Science
#biology
@evolutionscribe
@PLOSGenetics
⏯️https://t.co/cw5Lm3S6XE
⏯️https://t.co/O8igTr8iIR https://t.co/OwLW54P10K
Dec 12, 2022 · 48 likes · 5 shares · 11,623 followersView post →
MX
Medical Xpress
@medical_xpress · X
Immune system of modern Papuans shaped by #DNA from ancient Denisovans @plos @PLOSGenetics @PLOSONE https://t.co/UZctAHspqE https://t.co/gBoUEuijyS
Dec 8, 2022 · 21 likes · 8 shares · 172,874 followersView post →
B
bioRxiv
@biorxivpreprint · X
Denisovan introgression has shaped the immune system of present-day Papuans https://t.co/Brg4wz06EQ #bioRxiv
This week a paper looking at how ankylosaur tail clubs evolved for combat with other ankylosaurs was published. Researchers examined genetic influences of Denisovan DNA on human immune systems, revealing significant…
Denisovans are mysterious hominins whose traces live on in modern humans. This video explores their significant role in human evolution, including their impact in regions like Indonesia. Discover how Denisovans may…
Years ago I saw Stanford's Cavalli-Sforza, Yale's Kidd, and other sapientes claim that study of indigenous peoples' DNA would end the concept of race. It would not be used for things like mapping immune vulnerabilities of tribal peoples. So they claimed. https://t.co/phQ8ZhK3g2
Mar 1, 2023 · 3 likes · 2,015 followersView post →
BT
Bioinformatics Trends
@BinfoTrends · X
RT @jovwall: #DenisovanAncestry may be an Advantage for Protection against Pathogens since Denisovan variants were enriched for #GeneExpres…
Jan 15, 2023 · 1 share · 8,192 followersView post →
JW
Joe von Wallerstein
@jovwall · X
#DenisovanAncestry may be an Advantage for Protection against Pathogens since Denisovan variants were enriched for #GeneExpression in #ImmuneCells.
https://t.co/uJV7XuMuhs
Jan 15, 2023 · 1 like · 1 share · 411 followersView post →
"L'introgression de Denisoviens a façonné le système immunitaire des Papous d'aujourd'hui. Une étude révèle l'influence des ancêtres Denisoviens sur l'immunité des populations actuelles de Papouasie. #Denisoviens #systèmeimmunitaire #Papous #ancêtres https://t.co/UdfjTv34SD
ARTÍCULO ORIGINAL (acceso abierto)
Denisovan introgression has shaped the immune system of present-day Papuans
https://t.co/KP1CYE8K6N
via @PLOSGenetics
Dec 14, 2022 · 1 like · 1 share · 3,174 followersView post →
A
Alex
@AE_art_history · X
RT @manuelacasasoli: "Modern humans have admixed with multiple archaic hominins." Their immune systems may have picked up some survival tri…
Dec 12, 2022 · 5 shares · 1,222 followersView post →
PG
PLOS Genetics
@PLOSGenetics · X
RT @manuelacasasoli: "Modern humans have admixed with multiple archaic hominins." Their immune systems may have picked up some survival tri…
Dec 12, 2022 · 5 shares · 34,536 followersView post →
HY
Hao Yin
@HaoYin20 · X
RT @manuelacasasoli: "Modern humans have admixed with multiple archaic hominins." Their immune systems may have picked up some survival tri…
Dec 12, 2022 · 5 shares · 12,580 followersView post →
D
Diana
@onlybeci · X
RT @manuelacasasoli: "Modern humans have admixed with multiple archaic hominins." Their immune systems may have picked up some survival tri…
Dec 12, 2022 · 5 shares · 786 followersView post →
MC
Manuela Casasoli
@manuelacasasoli · X
"Modern humans have admixed with multiple archaic hominins." Their immune systems may have picked up some survival tricks when they mated with the mysterious Denisovans.
#Science
#biology
@evolutionscribe
@PLOSGenetics
⏯️https://t.co/cw5Lm3S6XE
⏯️https://t.co/O8igTr8iIR https://t.co/OwLW54P10K
Dec 12, 2022 · 48 likes · 5 shares · 11,623 followersView post →
Variation in gene expression might be key to understanding the consequences of admixture between modern humans and archaic hominins, as has been observed with Neanderthal DNA in other human populations https://t.co/eCkCZGvK7V
RT @PeaseRoland: Sticking with ancient DNA, we explore why Southeast Asian islanders can have up to 5% of their genomes inherited from exti…
Dec 8, 2022 · 2 shares · 12,753 followersView post →
TZ
The Conversation - Australia + New Zealand
@ConversationEDU · X
RT @DVespasiani: If you care about all the nerdy details check the article at this link
Dec 8, 2022 · 2 shares · 181,088 followersView post →
RP
Roland Pease
@PeaseRoland · X
Sticking with ancient DNA, we explore why Southeast Asian islanders can have up to 5% of their genomes inherited from extinct Eurasian Denisovans - tweaking the immune system is @UniMelb's @ee_reh_neh's new finding.
https://t.co/ACUeAWkTFC
Dec 8, 2022 · 5 likes · 2 shares · 3,417 followersView post →
DV
Davide Vespasiani
@DVespasiani · X
If you care about all the nerdy details check the article at this link
Dec 8, 2022 · 4 likes · 2 shares · 33 followersView post →
S
serrgv
@serrgv · X
RT @medical_xpress: Immune system of modern Papuans shaped by #DNA from ancient Denisovans @plos @PLOSGenetics @PLOSONE https://t.co/UZctAH…
Who Has Denisovan DNA? Neanderthal Traits & Benefits
News
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010470. Top Who Has Denisovan DNA Related Articles. Family Health History: Genetics ...