Proc Natl Acad Sci U S A December 2022 PMID 36508665

A de novo protein catalyzes the synthesis of semiconductor quantum dots.

Leah C Spangler, Yueyu Yao, Guangming Cheng, Nan Yao, Sarangan L Chari, Gregory D Scholes, Michael H Hecht

Mentions

24
Peak: 17 in Dec 2022
across 4 sources since Dec 2022

Extended reach

302,901
potential audience

Total likes

256

Video views

9,468

Mentions per month

Dec 2022 – Oct 2023

Where it's discussed

  • X / Twitter18 posts
  • News3 articles
  • YouTube2 videos
  • Blogs1 articles

AI synopsis

What people are saying

The discussions reflect a positive reception of the research, with comments like 'entering the biomineralization enzyme era' and questions about synthesizing other nanoparticles, emphasizing both curiosity and recognition of the research's transformative potential through supportive language and technical references.

AgreementModerate agreement

Most discussions recognize the significance of the engineered protein ConK in synthesizing quantum dots, indicating general agreement.

InterestModerate interest

Participants show moderate curiosity, referencing potential applications like biomineralization and enzyme development.

EngagementModerate engagement

Discussions include specific references to the research, such as questions about similar enzymes or broader implications, demonstrating active engagement.

ImpactModerate impact

Posts highlight the potential for advances in nanotechnology and biomineralization, suggesting moderate to high impact.

Abstract in brief

  • A de novo protein called ConK, designed from novel amino acid sequences, can catalyze the formation of semiconductor quantum dots by converting cysteine into sulfur, which then helps form CdS nanocrystals.
  • The CdS nanocrystals produced with ConK are about 3nm in size, have properties similar to chemically made quantum dots, and grow more slowly and differently than those from natural proteins, leading to more stable and phase-pure (zinc blende) nanocrystals.
  • This research suggests that using engineered proteins like ConK can improve the synthesis of high-quality quantum dots at room temperature, overcoming limitations of natural biomineralization in producing stable and pure nanocrystals.]

Top posts

Most liked on X and Bluesky
JM Mulet
@jmmulet · X

Materiales cuánticos utilizando síntesis de proteínas de novo. A de novo protein catalyzes the synthesis of semiconductor quantum dots | Proceedings of the National Academy of Sciences https://t.co/CMfzhTYk0l

Dec 21, 2022 · 11 likes · 2 shares · 74,328 followers View post →
Naoya KOBAYASHI
@kobnaoya · X

A de novo protein catalyzes the synthesis of semiconductor quantum dots | Proceedings of the National Academy of Sciences https://t.co/2ltUj3W8e2

Dec 14, 2022 · 8 likes · 2 shares · 1,212 followers View post →
PNASNews
@PNASNews · X

A study finds that a designed protein, ConK, which is not found in nature, can aid the stable synthesis of quantum dots and suggests that using ConK in nanocrystal synthesis may enable high-quality quantum dot synthesis at room temperature. In PNAS: https://t.co/w4zzzYYWRQ https://t.co/zbuyGS9VTe

Dec 14, 2022 · 6 likes · 181,584 followers View post →
Ventura's Lab
@PPMC_UAB · X

A de novo protein catalyzes the synthesis of semiconductor quantum dots | PNAS https://t.co/90jtSw47Hi

Jan 12, 2023 · 2 likes · 2,178 followers View post →
Trent Waddington
@QuantumG · X

https://t.co/I426if5IcK https://t.co/FLSXbbSncJ

Jan 10, 2023 · 2 likes · 2,065 followers View post →
ShorterLab
@ShorterLab · X

A de novo protein catalyzes the synthesis of semiconductor quantum dots: https://t.co/s1vANykMcp

Dec 13, 2022 · 1 like · 12,205 followers View post →

All mentions

Eswar Ramalingam
@eswaramalingam · X

Has anyone generated an enzyme that can catalyze Iridium quantum dots similar to Conk enzyme which catalyzes formation of CdS QD’s from cysteine as mentioned in this paper-https://t.co/6Bqq37nBFh @JCosmidis @buzbarstow

Oct 13, 2023 · 1 like · 387 followers View post →
Eswar Ramalingam
@eswaramalingam · X

Once we are able to discover cognate microbial enzymes capable of generating nanoparticles of various earth elements similar to this Princeton professor’s paper https://t.co/gr4FFghQRV we will truly enter the Biomineralization enzyme era in metallic alloy development.

Sep 12, 2023 · 387 followers View post →
Dr. Elden Wayne Whalen III, ShD
@wayne_effect · X

https://t.co/MnGLJI4UFR

Apr 30, 2023 · 1,305 followers View post →
Ventura's Lab
@PPMC_UAB · X

A de novo protein catalyzes the synthesis of semiconductor quantum dots | PNAS https://t.co/90jtSw47Hi

Jan 12, 2023 · 2 likes · 2,178 followers View post →
Mustafa O. Guler
@mustafaoguler · X

A de novo protein catalyzes the synthesis of semiconductor quantum dots | @PNASNews https://t.co/jaecV0YCij

Jan 12, 2023 · 1 like · 2,403 followers View post →
Trent Waddington
@QuantumG · X

https://t.co/I426if5IcK https://t.co/FLSXbbSncJ

Jan 10, 2023 · 2 likes · 2,065 followers View post →
emilio lindosa lucas
@411emilio · X

RT @jmmulet: Materiales cuánticos utilizando síntesis de proteínas de novo. A de novo protein catalyzes the synthesis of semiconductor qua…

Dec 21, 2022 · 2 shares · 4,865 followers View post →
Eduardo Villalobo
@ptu_us_es · X

RT @jmmulet: Materiales cuánticos utilizando síntesis de proteínas de novo. A de novo protein catalyzes the synthesis of semiconductor qua…

Dec 21, 2022 · 2 shares · 1,116 followers View post →
JM Mulet
@jmmulet · X

Materiales cuánticos utilizando síntesis de proteínas de novo. A de novo protein catalyzes the synthesis of semiconductor quantum dots | Proceedings of the National Academy of Sciences https://t.co/CMfzhTYk0l

Dec 21, 2022 · 11 likes · 2 shares · 74,328 followers View post →
しんしあ@バイオテクコミュニティ「BioSpace」モデレーター
@BioSpace9 · X

RT @kobnaoya: A de novo protein catalyzes the synthesis of semiconductor quantum dots | Proceedings of the National Academy of Sciences htt…

Dec 16, 2022 · 2 shares · 457 followers View post →
Weikun.Wu
@awakenkunkun · X

RT @kobnaoya: A de novo protein catalyzes the synthesis of semiconductor quantum dots | Proceedings of the National Academy of Sciences htt…

Dec 15, 2022 · 2 shares · 327 followers View post →
Naoya KOBAYASHI
@kobnaoya · X

A de novo protein catalyzes the synthesis of semiconductor quantum dots | Proceedings of the National Academy of Sciences https://t.co/2ltUj3W8e2

Dec 14, 2022 · 8 likes · 2 shares · 1,212 followers View post →
∃.くるくるパーティー・狂茶党☤
@1972tue0127 · X

自然界には存在しない設計されたタンパク質ConKが定量的な量子ドットの安定合成を助けることを発見し、ConKをナノ結晶合成に用いることで室温での高品質な量子ドット合成を可能にする可能性を示唆する研究結果を発表しました。PNASにて: https://t.co/D5UGvYOI75 https://t.co/LHoB1AX6Pu

Dec 14, 2022 · 1,575 followers View post →
PNASNews
@PNASNews · X

A study finds that a designed protein, ConK, which is not found in nature, can aid the stable synthesis of quantum dots and suggests that using ConK in nanocrystal synthesis may enable high-quality quantum dot synthesis at room temperature. In PNAS: https://t.co/w4zzzYYWRQ https://t.co/zbuyGS9VTe

Dec 14, 2022 · 6 likes · 181,584 followers View post →
Louis R Nemzer
@BiophysicsFL · X

"De novo proteins constructed from novel amino acid sequences are distinct from proteins that evolved in nature" A de novo protein catalyzes the synthesis of semiconductor quantum dots | Proceedings of the National Academy of Sciences https://t.co/PuXEG0RxZ9

Dec 13, 2022 · 4,363 followers View post →
ShorterLab
@ShorterLab · X

A de novo protein catalyzes the synthesis of semiconductor quantum dots: https://t.co/s1vANykMcp

Dec 13, 2022 · 1 like · 12,205 followers View post →
James V. Kohl
@microRNApro · X

Whoops. I missed it. Did you #Twitterfiles6? "A de novo protein catalyzes the synthesis of semiconductor quantum dots" https://t.co/KVlnedSWth 12/12/22 "De novo proteins constructed from novel amino acid sequences are distinct from proteins that evolved in nature." https://t.co/27pVjl9SCf

Dec 13, 2022 · 2,577 followers View post →
SparkInnovationsCorp
@SparkInnovsCorp · X

A de novo protein catalyzes the synthesis of semiconductor quantum dots | Proceedings of the National Academy of Sciences - https://t.co/FjBKVKxFRA https://t.co/x8eAy5i11e

Dec 12, 2022 · 36 followers View post →
Using designer proteins to make quantum dots
News

2022, DOI: 10.1073/pnas.2204050119). Quantum dots are semiconductor nanocrystals that shine in a range of bright, pure colors depending on ...

Dec 28, 2022 View →
Chemists created quantum dots at room temp using lab-designed ...
Blogs

DOI: 10.1073/pnas.2204050119. Picks for you. A new method of distance measurement for systems like GPS · Scientists demonstrated a network of ...

Dec 13, 2022 View →
Quantum dots at room temp, using lab-designed protein | ScienceDaily
News

Scholes and Michael H. Hecht. A de novo protein catalyzes the synthesis of semiconductor quantum dots. PNAS, 2022 DOI: 10.1073/pnas.2204050119 ...

Dec 13, 2022 View →
Chemists create quantum dots at room temperature using lab ...
News

DOI: 10.1073/pnas.2204050119. www.pnas.org/doi/10.1073/pnas.2204050119. Journal information: Proceedings of the National Academy of Sciences.

Dec 12, 2022 View →