BMC Med December 2022 PMID 36575472

Obese visceral fat tissue inflammation: from protective to detrimental?

Hubert Kolb

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Mentions

41
Peak: 14 in Apr 2023
across 5 sources since Dec 2022

Extended reach

334,177
potential audience

Total likes

101

Video views

3,308

Mentions per month

Dec 2022 – Aug 2025

Where it's discussed

  • X / Twitter29 posts
  • News6 articles
  • YouTube2 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

These discussions illustrate a keen interest in how visceral fat initially acts as a protective barrier against excess nutrients, as explained in posts referencing its role in filtering oxidized lipids. The tone varies from recognition of the protective mechanism to concern about its transition toward harmful inflammation, evidenced by phrases like 'from protective to detrimental' and mentions of immune processes, indicating users are engaging deeply with the implications of the findings.

AgreementModerate agreement

Most discussions acknowledge the dual role of visceral fat, recognizing its initial protective function that becomes harmful over time, reflecting moderate consensus with some nuanced opinions.

InterestHigh interest

Posts show strong curiosity, highlighting frequent mentions of mechanisms of inflammation and its progression, along with terms like 'transform' and 'detrimental,' indicating high engagement and relevance.

EngagementModerate engagement

Several comments reference specific biological processes such as immune activation, adipocyte stress, and inflammation markers, demonstrating a deep engagement with the material and scientific concepts.

ImpactModerate impact

The discussions suggest an understanding that this research could influence the understanding of obesity-related health conditions, but there’s a cautious perception of immediate impact, yielding a moderate score.

Abstract in brief

  • Obese visceral fat inflammation begins as a protective response to excess nutrients aimed at restoring tissue balance, but over time it can lead to tissue damage.
  • Chronic overnutrition causes adipocyte stress, leading to immune activation, cell death, and structural changes like fibrosis, which can impair fat tissue function.
  • The inflammation involves a complex interplay of adipocyte signals, immune cells, and tissue remodeling, with a shift from protective to harmful effects as the condition worsens.]

Top posts

Most liked on X and Bluesky
Dr Alexey Kulikov
@KulikovUNIATF · X

It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat. New article explores mechanisms how over nutrition could lead to such tissue #inflammation transform from protective to detrimental. https://t.co/nprJm5f656 https://t.co/CmXGhKglxF

Apr 29, 2023 · 29 likes · 12 shares · 62,991 followers View post →
Dr Jean Michel Kayumba
@DrKayumba · X

La production des facteurs pro-inflammatoires (IL-1,IL-6, NK-alpha) et la suppression du facteur anti-inflammatoire (adiponectine) sont à la base de la survenue du syndrome métabolique. Nous pouvons vous aider à le prévenir. https://t.co/cgCTpl40ML https://t.co/XskWySOzDl

Jun 29, 2023 · 7 likes · 1 share · 13,845 followers View post →
Tucker Goodrich
@TuckerGoodrich · X

@siobhan_huggins @Peter_InNorfolk I think part of the purpose of visceral fat is to filter oxidized lipids out of chylomicrons. If it's not fulfilling that role in lipedema it could help explain it. Kolb, Hubert. 2022. “Obese Visceral Fat Tissue Inflammation: From Protective to Detrimental?” BMC Medicine 20 (1):

Jul 17, 2025 · 6 likes · 1 share · 28,290 followers View post →
Adipose Papers
@adipose_papers · X

Obese visceral fat tissue inflammation: from protective to detrimental? https://t.co/82gZXKSIK1 https://t.co/wtKbNn7Qw8

Dec 28, 2022 · 4 likes · 2 shares · 2,450 followers View post →
Kat Fu, M.S., M.S.
@thekatfu · X

May 10, 2025 · 3 likes · 17,964 followers View post →
BMC Medicine
@BMCMedicine · X

New Review article from Hubert Kolb describes visceral fat tissue changes in response to chronic overnutrition: Obese visceral fat tissue inflammation: from protective to detrimental? https://t.co/EzcfZrsSSp #obesity #inflammation #immunecells https://t.co/g2kXDx2B0p

Dec 28, 2022 · 1 like · 9,191 followers View post →

All mentions

Canyon Dood
@DoodleCanyon · X

RT @TuckerGoodrich: @siobhan_huggins @Peter_InNorfolk I think part of the purpose of visceral fat is to filter oxidized lipids out of chylo…

Jul 17, 2025 · 1 share · 564 followers View post →
Tucker Goodrich
@TuckerGoodrich · X

@siobhan_huggins @Peter_InNorfolk I think part of the purpose of visceral fat is to filter oxidized lipids out of chylomicrons. If it's not fulfilling that role in lipedema it could help explain it. Kolb, Hubert. 2022. “Obese Visceral Fat Tissue Inflammation: From Protective to Detrimental?” BMC Medicine 20 (1):

Jul 17, 2025 · 6 likes · 1 share · 28,290 followers View post →
Kat Fu, M.S., M.S.
@thekatfu · X

May 10, 2025 · 3 likes · 17,964 followers View post →
ScienceBank
@The_ScienceBank · X

[2 of 2] Initially, it serves as a protective response to cope with excess nutrients. However, over time, this inflammation may become detrimental to tissue health. Source: https://t.co/Js57Q6C1GJ - BMC medicine

Dec 11, 2023 · 49 followers View post →
Ainul
@ainuljusti · X

Save sini https://t.co/RvodBcNwOF

Dec 11, 2023 · 5 followers View post →
javierbutra
@javierbutra · X

Key messages and gaps of knowledge From: Obese visceral fat tissue inflammation: from protective to detrimental? https://t.co/SkxKMpS7lc

Sep 14, 2023 · 14,338 followers View post →
Domi Iboko
@DomiIbokos · X

RT @DrKayumba: La production des facteurs pro-inflammatoires (IL-1,IL-6, NK-alpha) et la suppression du facteur anti-inflammatoire (adipone…

Jun 29, 2023 · 1 share · 3,770 followers View post →
Dr Jean Michel Kayumba
@DrKayumba · X

La production des facteurs pro-inflammatoires (IL-1,IL-6, NK-alpha) et la suppression du facteur anti-inflammatoire (adiponectine) sont à la base de la survenue du syndrome métabolique. Nous pouvons vous aider à le prévenir. https://t.co/cgCTpl40ML https://t.co/XskWySOzDl

Jun 29, 2023 · 7 likes · 1 share · 13,845 followers View post →
Rossana Alessandrello
@realessandrello · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

May 1, 2023 · 12 shares · 322 followers View post →
Neil Floch MD
@NeilFlochMD · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 130,129 followers View post →
The Academy of Public Health
@TheWaaph · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 9,326 followers View post →
Leena M S
@LeenaMS5 · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 91 followers View post →
CleanEarth4Kids.org
@CleanEarth4Kids · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 1,146 followers View post →
Prof. Sunit K. Singh
@DrSunitKSingh · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 6,461 followers View post →
Kirpa Ram, PhD
@KirpaRamBHU · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 943 followers View post →
Seydou BAH
@seydoubah · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 1,875 followers View post →
sudeep
@sudeepkhatri · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 8,716 followers View post →
Dr. Rajesh Jain, MD
@DiabetesAsiaOrg · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 1,674 followers View post →
ProfXicoAlexandre
@XicoAlexndre · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 6,696 followers View post →
Sarah De Saeger
@saeger_sarah · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 816 followers View post →
Latif Patel
@LatifPatel14 · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 2,061 followers View post →
Asiya AbdulRaheem
@minheyo_keun · X

RT @KulikovUNIATF: It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat.…

Apr 29, 2023 · 12 shares · 1,990 followers View post →
Dr Alexey Kulikov
@KulikovUNIATF · X

It was known that #obesity usually is accompanied by inflammation of fat tissue, with a prominent role of visceral fat. New article explores mechanisms how over nutrition could lead to such tissue #inflammation transform from protective to detrimental. https://t.co/nprJm5f656 https://t.co/CmXGhKglxF

Apr 29, 2023 · 29 likes · 12 shares · 62,991 followers View post →
Wanida
@Wanida_Chua · X

Jan 23, 2023 · 1,475 followers View post →
AdlungLab Systems Immunology
@AdlungLab · X

Review: "Obese visceral fat tissue inflammation: from protective to detrimental?" in @BMCMedicine https://t.co/gtQT2fV5Zx

Dec 31, 2022 · 778 followers View post →
Mitominder
@Mitominder · X

RT @adipose_papers: Obese visceral fat tissue inflammation: from protective to detrimental? https://t.co/82gZXKSIK1 https://t.co/wtKbNn7Qw8

Dec 28, 2022 · 2 shares · 2,259 followers View post →
BMC Medicine
@BMCMedicine · X

New Review article from Hubert Kolb describes visceral fat tissue changes in response to chronic overnutrition: Obese visceral fat tissue inflammation: from protective to detrimental? https://t.co/EzcfZrsSSp #obesity #inflammation #immunecells https://t.co/g2kXDx2B0p

Dec 28, 2022 · 1 like · 9,191 followers View post →
Amaya Lopez-Pascual
@amayalpzp · X

RT @adipose_papers: Obese visceral fat tissue inflammation: from protective to detrimental? https://t.co/82gZXKSIK1 https://t.co/wtKbNn7Qw8

Dec 28, 2022 · 2 shares · 275 followers View post →
Adipose Papers
@adipose_papers · X

Obese visceral fat tissue inflammation: from protective to detrimental? https://t.co/82gZXKSIK1 https://t.co/wtKbNn7Qw8

Dec 28, 2022 · 4 likes · 2 shares · 2,450 followers View post →