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Adv Ther March 2023 PMID 36609679

Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology.

Evan S Sinnathamby, Peter P Issa, Logan Roberts, Haley Norwood, Kevin Malone, Harshitha Vemulapalli, Shahab Ahmadzadeh, Elyse M Cornett, Sahar Shekoohi, Alan D Kaye

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Mentions

18
Peak: 4 in Mar 2023
across 4 sources since Jan 2023

Extended reach

95,977
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826

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32,277

Mentions per month

Jan 2023 – Jun 2025

Where it's discussed

  • News9 articles
  • X / Twitter6 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Overall, the discussions demonstrate a positive attitude toward the article's relevance, with users sharing educational resources like videos and summaries, and highlighting new therapeutic approaches. For example, references to Garadicimab and clinical reviews show an active effort to connect research findings with practical applications, with a tone that balances curiosity and appreciation for advancements in understanding hereditary angioedema.

AgreementModerate agreement

Most posts recognize the importance of the publication, with some explicitly affirming its value in understanding hereditary angioedema.

InterestModerate interest

Discussions show moderate interest, with posts referencing new treatments like Garadicimab and emphasizing the need to understand the condition.

EngagementModerate engagement

Posts include shares of related videos and summaries, indicating a genuine effort to engage deeply with the content.

ImpactModerate impact

The discussions suggest that the publication has potential influence on both clinical understanding and treatment, demonstrated by mentions of pharmacology and clinical implications.

Abstract in brief

  • Hereditary angioedema (HAE) is a genetic disorder caused by mutations affecting the C1 esterase inhibitor, leading to episodes of swelling and sometimes abdominal pain, with types I, II, and III based on specific genetic mutations.
  • The condition typically presents in early adulthood with symptoms like nonpitting swelling, and triggers such as stress, infections, or trauma; laboratory tests show abnormal C1INH levels and elevated bradykinin.
  • Treatment options include immediate infusion of C1INH, receptor antagonists, and kallikrein inhibitors during attacks, as well as long-term preventive therapies like regular C1INH infusions to reduce the frequency and severity of symptoms.]
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Top posts

Most liked on X and Bluesky
Critical Care Reviews
@CritCareReviews · X

Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology CCR Journal Watch https://t.co/Sp06oA6IDG https://t.co/kz0c78gmCZ

Mar 26, 2023 · 13 likes · 4 shares · 62,123 followers View post →
Heba
@hebama.bsky.social · Bluesky

حلقة مهمة youtu.be/wNh8pjaRTPk?...

Feb 14, 2025 · 2 likes · 1 share View post →
Pharmacology Insights
@PharmacoIns · X

Garadicimab for Hereditary Angioedema: How It Works https://t.co/tDtvbDmPwx #Pharmacology #MedEd #MonoclonalAntibody #LearnMedicine #Andembry

Jun 28, 2025 · 1 like · 12 followers View post →
Advances in Therapy
@AdvancesTherapy · X

This newly published review aims to thoroughly understand hereditary #angioedema, its clinical presentation, and how to treat it: https://t.co/LTwmIYg1C1 https://t.co/bZmThg6GF5

Jan 9, 2023 · 1,192 followers View post →
Dr A.Hakim Aljawfy
@AljawfyA · X

RT @CritCareReviews: Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology CCR Journal Watch https://t.co/Sp06oA6ID…

Mar 26, 2023 · 4 shares · 212 followers View post →
Romain Batton, MD, MSc
@romain_bttn · X

RT @CritCareReviews: Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology CCR Journal Watch https://t.co/Sp06oA6ID…

Mar 27, 2023 · 4 shares · 36 followers View post →

All mentions

Pharmacology Insights
@PharmacoIns · X

Garadicimab for Hereditary Angioedema: How It Works https://t.co/tDtvbDmPwx #Pharmacology #MedEd #MonoclonalAntibody #LearnMedicine #Andembry

Jun 28, 2025 · 1 like · 12 followers View post →
Heba
@hebama.bsky.social · Bluesky

حلقة مهمة youtu.be/wNh8pjaRTPk?...

Feb 14, 2025 · 2 likes · 1 share View post →
Romain Batton, MD, MSc
@romain_bttn · X

RT @CritCareReviews: Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology CCR Journal Watch https://t.co/Sp06oA6ID…

Mar 27, 2023 · 4 shares · 36 followers View post →
Dr A.Hakim Aljawfy
@AljawfyA · X

RT @CritCareReviews: Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology CCR Journal Watch https://t.co/Sp06oA6ID…

Mar 26, 2023 · 4 shares · 212 followers View post →
FOAM_O53
@FOAM_O53 · X

RT @CritCareReviews: Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology CCR Journal Watch https://t.co/Sp06oA6ID…

Mar 26, 2023 · 4 shares · 1 followers View post →
Critical Care Reviews
@CritCareReviews · X

Hereditary Angioedema: Diagnosis, Clinical Implications, and Pathophysiology CCR Journal Watch https://t.co/Sp06oA6IDG https://t.co/kz0c78gmCZ

Mar 26, 2023 · 13 likes · 4 shares · 62,123 followers View post →
Advances in Therapy
@AdvancesTherapy · X

This newly published review aims to thoroughly understand hereditary #angioedema, its clinical presentation, and how to treat it: https://t.co/LTwmIYg1C1 https://t.co/bZmThg6GF5

Jan 9, 2023 · 1,192 followers View post →
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