Am J Psychiatry February 2023 PMID 36628514

Evaluating the Evidence for Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma.

Ziv Ben-Zion, Tobias R Spiller, Jackob N Keynan, Roee Admon, Ifat Levy, Israel Liberzon, Arieh Y Shalev, Talma Hendler, Ilan Harpaz-Rotem

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Mentions

102
Peak: 59 in Jan 2023
across 6 sources since Jan 2023

Extended reach

457,537
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Total likes

183

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Jan 2023 – Dec 2025

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AI synopsis

What people are saying

Discussions demonstrate a balanced perspective, with some posts expressing excitement about new research endeavors and others emphasizing the importance of caution due to replication challenges, as seen in phrases like 'call for caution' and references to 'failure to replicate.' The tone and choice of words reflect a nuanced debate about the reliability and implications of neurobiological markers in trauma-related psychiatric vulnerability, leading to moderate scores across all dimensions.

AgreementNeither agree nor disagree

Most discussions call for caution and acknowledge the difficulty in replicating findings, reflecting a neutral stance rather than outright agreement or disagreement.

InterestModerate interest

The discussions show some curiosity, especially around the challenges of neuroimaging research and replication issues, but the overall enthusiasm appears moderate.

EngagementModerate engagement

Participants reference specific studies, mention editors, and discuss implications, indicating a moderate level of in-depth engagement.

ImpactNeutral impact

The discourse highlights important scientific concerns but does not suggest the publication has had a transformative impact, thus a neutral impact score.

Abstract in brief

  • Recent research aims to classify psychiatric vulnerability after trauma using objective brain-based markers rather than subjective symptom reports, to improve personalized treatment.
  • A 2021 study by Stevens et al attempted to replicate earlier findings by identifying brain-based biotypes linked to posttraumatic symptom patterns, but their results showed different neural clusters not directly related to symptoms.
  • The study suggests that brain-based biotypes may not be easily generalizable across different populations, highlighting the need for further research to find consistent neurobiological subtypes of trauma-related mental health issues.]

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Ziv Ben-Zion
@ZivBenZion1 · X

Can we replicate the previously identified brain-based biotypes of posttraumatic psychopathology? Thrilled to share our work that was published today in @APAPubJournals American Journal of Psychiatry!

Jan 11, 2023 · 120 likes · 40 shares · 1,284 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

A non-replication study @PTSDStressLab @YaleDecisionLab suggests caution is warranted when attempting to define neuroimaging-based #biotypes of psychiatric vulnerability. @ZivBenZion1 @TRSpiller @RoeeAdmon @ifat_levy @harpaz_l https://t.co/LQTCL5NWGU https://t.co/Cjb9r1P8dd

Jan 11, 2023 · 14 likes · 10 shares · 11,606 followers View post →
Jennifer Stevens
@DrJenniStevens · X

What can we learn from a failure to replicate? https://t.co/NlcaMOg7f6 Some thoughts... https://t.co/Ny8BnlzDsj

Jan 11, 2023 · 13 likes · 2 shares · 1,466 followers View post →
Ziv Ben-Zion
@ZivBenZion1 · X

American Journal of Psychiatry (#AJP) Deputy Editor, Daniel S. Pine, discusses our recent work (@TRSpiller @nimrodke1 @RoeeAdmon @HendlerLab @ifat_levy @harpaz_l) in the February 2023 AJP Editor Spotlight https://t.co/DUcE1hurqS

Feb 18, 2023 · 13 likes · 2 shares · 1,284 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

Evaluating the Evidence for Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma,” by Ziv Ben-Zion, Ph.D., et al. https://t.co/VPEAm2X0bN

Feb 17, 2023 · 7 likes · 3 shares · 11,606 followers View post →
Ziv Ben-Zion
@ZivBenZion1 · X

@APAPubJournals Special thanks to @DrJenniStevens for her commendable collaboration, to my amazing colleagues @TRSpiller @nimrodke1 @RoeeAdmon and great mentors @ifat_levy @HendlerLab @harpaz_l @PTSDStressLab @YaleDecisionLab!

Feb 1, 2023 · 6 likes · 1,284 followers View post →

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Nalan Zhan
@nalanzhan · X

RT @ZivBenZion1: Can we replicate the previously identified brain-based biotypes of posttraumatic psychopathology? Thrilled to share our wo…

Jun 15, 2023 · 40 shares · 70 followers View post →
Yale PTSD Stress Lab
@PTSDStressLab · X

RT @ZivBenZion1: American Journal of Psychiatry (#AJP) Deputy Editor, Daniel S. Pine, discusses our recent work (@TRSpiller @nimrodke1 @Roe…

Feb 18, 2023 · 2 shares · 1,016 followers View post →
Yale Decision Neuroscience Lab
@YaleDecisionLab · X

RT @ZivBenZion1: American Journal of Psychiatry (#AJP) Deputy Editor, Daniel S. Pine, discusses our recent work (@TRSpiller @nimrodke1 @Roe…

Feb 18, 2023 · 2 shares · 243 followers View post →
Ziv Ben-Zion
@ZivBenZion1 · X

American Journal of Psychiatry (#AJP) Deputy Editor, Daniel S. Pine, discusses our recent work (@TRSpiller @nimrodke1 @RoeeAdmon @HendlerLab @ifat_levy @harpaz_l) in the February 2023 AJP Editor Spotlight https://t.co/DUcE1hurqS

Feb 18, 2023 · 13 likes · 2 shares · 1,284 followers View post →
Yale PTSD Stress Lab
@PTSDStressLab · X

RT @APAPubJournals: Evaluating the Evidence for Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma,” by Ziv…

Feb 18, 2023 · 3 shares · 1,016 followers View post →
Yale Decision Neuroscience Lab
@YaleDecisionLab · X

RT @APAPubJournals: Evaluating the Evidence for Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma,” by Ziv…

Feb 18, 2023 · 3 shares · 243 followers View post →
Ziv Ben-Zion
@ZivBenZion1 · X

RT @APAPubJournals: Evaluating the Evidence for Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma,” by Ziv…

Feb 18, 2023 · 3 shares · 1,284 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

Evaluating the Evidence for Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma,” by Ziv Ben-Zion, Ph.D., et al. https://t.co/VPEAm2X0bN

Feb 17, 2023 · 7 likes · 3 shares · 11,606 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

AJP Deputy Editor Danny Pine highlights two articles from the February 2023 issue. https://t.co/I1gl10bvI0

Feb 17, 2023 · 1 like · 11,606 followers View post →
Dr. John M. Earl Waugh
@DrWaugh1 · X

RT @ZivBenZion1: Can we replicate the previously identified brain-based biotypes of posttraumatic psychopathology? Thrilled to share our wo…

Feb 8, 2023 · 40 shares · 390 followers View post →
Ziv Ben-Zion
@ZivBenZion1 · X

@APAPubJournals Special thanks to @DrJenniStevens for her commendable collaboration, to my amazing colleagues @TRSpiller @nimrodke1 @RoeeAdmon and great mentors @ifat_levy @HendlerLab @harpaz_l @PTSDStressLab @YaleDecisionLab!

Feb 1, 2023 · 6 likes · 1,284 followers View post →
NEUROADS Lab
@neuroads_lab · X

RT @CommsPsychol: Based on new analyses testing for a conceptual replication of earlier results, @ZivBenZion1 et al call for caution when i…

Jan 19, 2023 · 6 shares · 1,062 followers View post →
orduek
@orduek · X

RT @CommsPsychol: Based on new analyses testing for a conceptual replication of earlier results, @ZivBenZion1 et al call for caution when i…

Jan 19, 2023 · 6 shares · 321 followers View post →
Yale Decision Neuroscience Lab
@YaleDecisionLab · X

RT @CommsPsychol: Based on new analyses testing for a conceptual replication of earlier results, @ZivBenZion1 et al call for caution when i…

Jan 18, 2023 · 6 shares · 243 followers View post →
Yale PTSD Stress Lab
@PTSDStressLab · X

RT @CommsPsychol: Based on new analyses testing for a conceptual replication of earlier results, @ZivBenZion1 et al call for caution when i…

Jan 18, 2023 · 6 shares · 1,016 followers View post →
Ziv Ben-Zion
@ZivBenZion1 · X

RT @CommsPsychol: Based on new analyses testing for a conceptual replication of earlier results, @ZivBenZion1 et al call for caution when i…

Jan 18, 2023 · 6 shares · 1,284 followers View post →
Communications Psychology
@CommsPsychol · X

Based on new analyses testing for a conceptual replication of earlier results, @ZivBenZion1 et al call for caution when identifying neuroimaging-based #biotypes of psychiatric vulnerability in post-traumatic participants. @PTSDStrassLab @YaleDecisionLab https://t.co/I3Q1xp4Mn7

Jan 18, 2023 · 5 likes · 6 shares · 1,393 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
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Lana Ruvolo, PhD
@ScientificRuvvy · X

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Anat D
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martina
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Benjamin Perry
@Benjamin_EPerry · X

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orduek
@orduek · X

RT @DrJenniStevens: What can we learn from a failure to replicate? https://t.co/NlcaMOg7f6 Some thoughts... https://t.co/Ny8BnlzDsj

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Christophe B
@CBedeaux · X

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Shruti (they/she)
@shrutibkoch · X

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Yale School of Medicine
@YaleMed · X

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Center for Mental Health Research & Initiative
@Cemhri · X

Evaluating the Evidence for Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma https://t.co/3ybEHx2v4H

Jan 12, 2023 · 1,287 followers View post →
Stephanie Noble (@sneuroble.bsky.social)
@sNeuroble · X

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yoshiyuki nishio
@nishiokov · X

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Global Collaboration on Traumatic Stress (GC-TS)
@Global_Trauma · X

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nicola sambuco
@NicolaSambuco · X

RT @DrJenniStevens: What can we learn from a failure to replicate? https://t.co/NlcaMOg7f6 Some thoughts... https://t.co/Ny8BnlzDsj

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Cognitive Neuropsychiatry
@CogNPsychiatry · X

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Caesar Liu
@CaesarLiu_12 · X

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Isabelle Rosso
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Joseph Chen
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Carolyn Rodriguez
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Mike Gara
@garami53 · X

RT @APAPubJournals: A non-replication study @PTSDStressLab @YaleDecisionLab suggests caution is warranted when attempting to define neuroim…

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Daniel P. Moriarity
@dp_moriarity · X

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Jennifer Stevens
@DrJenniStevens · X

What can we learn from a failure to replicate? https://t.co/NlcaMOg7f6 Some thoughts... https://t.co/Ny8BnlzDsj

Jan 11, 2023 · 13 likes · 2 shares · 1,466 followers View post →
Roxana Jabbarinejad(She/Her) رکسانا جباری نژاد
@RoxanaJabbarin · X

RT @APAPubJournals: A non-replication study @PTSDStressLab @YaleDecisionLab suggests caution is warranted when attempting to define neuroim…

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Corinna Schulz
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orduek
@orduek · X

RT @APAPubJournals: A non-replication study @PTSDStressLab @YaleDecisionLab suggests caution is warranted when attempting to define neuroim…

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Yale Decision Neuroscience Lab
@YaleDecisionLab · X

RT @APAPubJournals: A non-replication study @PTSDStressLab @YaleDecisionLab suggests caution is warranted when attempting to define neuroim…

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Yale PTSD Stress Lab
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RT @APAPubJournals: A non-replication study @PTSDStressLab @YaleDecisionLab suggests caution is warranted when attempting to define neuroim…

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Journals of The American Psychiatric Association
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RT @ZivBenZion1: Can we replicate the previously identified brain-based biotypes of posttraumatic psychopathology? Thrilled to share our wo…

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Sarah Danböck
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RT @ZivBenZion1: Can we replicate the previously identified brain-based biotypes of posttraumatic psychopathology? Thrilled to share our wo…

Jan 11, 2023 · 40 shares · 293 followers View post →
Ziv Ben-Zion
@ZivBenZion1 · X

RT @APAPubJournals: A non-replication study @PTSDStressLab @YaleDecisionLab suggests caution is warranted when attempting to define neuroim…

Jan 11, 2023 · 10 shares · 1,284 followers View post →
Sam Cooper @samcooper.bsky.social
@samcooper_phd · X

RT @ZivBenZion1: Can we replicate the previously identified brain-based biotypes of posttraumatic psychopathology? Thrilled to share our wo…

Jan 11, 2023 · 40 shares · 289 followers View post →
Megan Paterson
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RT @ZivBenZion1: Can we replicate the previously identified brain-based biotypes of posttraumatic psychopathology? Thrilled to share our wo…

Jan 11, 2023 · 40 shares · 23 followers View post →
Journals of The American Psychiatric Association
@APAPubJournals · X

A non-replication study @PTSDStressLab @YaleDecisionLab suggests caution is warranted when attempting to define neuroimaging-based #biotypes of psychiatric vulnerability. @ZivBenZion1 @TRSpiller @RoeeAdmon @ifat_levy @harpaz_l https://t.co/LQTCL5NWGU https://t.co/Cjb9r1P8dd

Jan 11, 2023 · 14 likes · 10 shares · 11,606 followers View post →
Leonhard Schilbach
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nicola sambuco
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RT @medical_xpress: Can neuroimaging reveal the roots of #psychiatricdisorders? Not just yet, says study @yale https://t.co/Cr78oCAsfb http…

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Dr. Samadov Aabdić
@samadovaabditch · X

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@physorg_health · X

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@medical_xpress · X

Can neuroimaging reveal the roots of #psychiatricdisorders? Not just yet, says study @yale https://t.co/Cr78oCAsfb https://t.co/z33h9sG0M9

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Noah S Philip MD
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Chelsea Xu
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Nachshon Korem
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orduek
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Yale PTSD Stress Lab
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Ziv Ben-Zion
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Can we replicate the previously identified brain-based biotypes of posttraumatic psychopathology? Thrilled to share our work that was published today in @APAPubJournals American Journal of Psychiatry!

Jan 11, 2023 · 120 likes · 40 shares · 1,284 followers View post →
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... 10.1176/appi.ajp.20220271). - Мичиганское исследование показало важность социальной поддержки (например помощь близких или выслушивание) в ...

Feb 17, 2022 View →
Clinical Psychologists/psychiatrists, I need help with diagnosing ...
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Jan 25, 2022 View →
**A neurostructural biomarker of dissociative amnesia: a ... - Facebook
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Jul 13, 2021 View →
What is a #biomarker? Why are biomarkers key to advancing ...
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Jun 2, 2021 View →
EEG biomarkers double the efficacy or medication selection for MDD ...
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Jan 25, 2021 View →
Evaluating the evidence for a neuroimaging subtype of ...
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https://doi.org/10.1176/appi.ajp.20220271 · Crossref. Richard A. Bryant,. Controversies in Posttraumatic Stress Disorder, Toward a Science of ...

Nov 4, 2020 View →
Can an EEG detect psychosis like schizophrenia or other depressive ...
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Oct 23, 2019 View →
"Researchers have shown that a type of magnetic resonance ...
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Feb 18, 2019 View →
Researchers have discovered biomarkers that may explain why ...
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Jan 26, 2019 View →
A new neuroimaging study shows a link between childhood post ...
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Oct 31, 2016 View →
EEG scans could help diagnose awareness in patients with a ...
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Jul 27, 2016 View →