PubHawk
Adv Sci (Weinh) March 2023 PMID 36642846

Deep Eutectic Solvents for Subcutaneous Delivery of Protein Therapeutics.

Alexander M Curreri, Jayoung Kim, Michael Dunne, Pavimol Angsantikul, Morgan Goetz, Yongsheng Gao, Samir Mitragotri

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Mentions

4
Peak: 3 in Jan 2023
across 2 sources since Jan 2023

Extended reach

24,494
potential audience

Total likes

17

Video views

203

Mentions per month

Jan 2023 – Jun 2023

Where it's discussed

  • X / Twitter3 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions emphasize the innovative use of deep eutectic solvents in enhancing protein delivery, with phrases like 'exciting capability' and recognition of the research leadership. The tone reflects a positive outlook and curiosity, but they stop short of expressing definitive real-world impact at this stage.

AgreementModerate agreement

Most discussions are enthusiastic and recognize the potential of deep eutectic solvents, as seen in phrases like 'exciting capability' and acknowledgment of the research's significance.

InterestHigh interest

The discussions demonstrate high interest, with participants highlighting novel aspects and potential benefits of the study, indicating curiosity and excitement.

EngagementModerate engagement

The posts include references to the research details and the researchers involved, showing thoughtful engagement rather than surface-level mentions.

ImpactModerate impact

While the discussions are optimistic about the future applications, the overall tone suggests the immediate impact remains to be fully realized, so a moderate score reflects their anticipation.

Abstract in brief

  • This article discusses a new delivery method using deep eutectic solvents to improve how protein medicines, like insulin and monoclonal antibodies, are absorbed when injected under the skin, addressing current limitations such as slow absorption and poor effectiveness.
  • The study shows that this deep eutectic-based approach can increase the absorption of proteins by up to 200% and make insulin act faster than existing rapid-acting formulas, by reducing interactions between the proteins and the tissue around the injection site.
  • Safety tests confirm that these deep eutectic formulations are safe for injections, opening up new possibilities for more effective subcutaneous delivery of protein therapeutics in the future.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Pavimol (Keep) Angsantikul
@PavimolAKeep · X

Check out our new publication on the exciting capability of novel deep eutectic solvents in enhancing the subcutaneous delivery of biologics. The work was led by Alex Curreri and @jay_jayoungkim from @SMitragotri lab. https://t.co/4PgWPbrarh

Jan 16, 2023 · 17 likes · 1 share · 196 followers View post →
Population Council
@Pop_Council · X

RT @PavimolAKeep: Check out our new publication on the exciting capability of novel deep eutectic solvents in enhancing the subcutaneous de…

Jan 17, 2023 · 1 share · 23,123 followers View post →

All mentions

Population Council
@Pop_Council · X

RT @PavimolAKeep: Check out our new publication on the exciting capability of novel deep eutectic solvents in enhancing the subcutaneous de…

Jan 17, 2023 · 1 share · 23,123 followers View post →
Dataemia
@Dataemia · X

Deep Eutectic Solvents for Subcutaneous Delivery of Protein Therapeutics - https://t.co/ykHgasvtY6

Jan 17, 2023 · 969 followers View post →
Pavimol (Keep) Angsantikul
@PavimolAKeep · X

Check out our new publication on the exciting capability of novel deep eutectic solvents in enhancing the subcutaneous delivery of biologics. The work was led by Alex Curreri and @jay_jayoungkim from @SMitragotri lab. https://t.co/4PgWPbrarh

Jan 16, 2023 · 17 likes · 1 share · 196 followers View post →