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Several posts discuss the molecular effects of leptin on brain and metabolic functions, such as its neuroprotective roles and links to neurodegenerative diseases, showing a curiosity for biochemical mechanisms. Usage of technical terms like 'DNA methylation', 'transcriptomics', and 'mitochondrial disorder' reflect a deeper engagement and imply that these discussions could shape future research or therapeutic strategies.
Most discussions recognize the significance of leptin's role in neurological and metabolic health, with some expressing strong support for ongoing research.
Posts show moderate interest, discussing various research methods and findings, though not all deeply detail the mechanisms.
Participants reference molecular pathways, mitochondrial functions, and clinical implications, indicating an active engagement with the topic.
The discussions suggest the article's findings could influence future research directions or treatments, highlighting a modest but meaningful impact.
Retroviruses are trending, another interesting article by an italian team about COVID-19 News: SARS-CoV-2 Reactivation Of Human Endogenous Retroviruses Contributes To Kawasaki Disease, MIS-C And Even COVID-19 Severity! www.thailandmedical.news/news/covid-1... www.mdpi.com/1422-0067/24...
www.mdpi.com/2076-3425/13... www.mdpi.com/1422-0067/24... www.researchgate.net/profile/Xian... journals.viamedica.pl/neurologia_n... mdpi-res.com/d_attachment...
Possible Pathogenesis and Prevention of Long COVID: SARS-CoV-2-Induced Mitochondrial Disorder
Interesting #Aorta Transcriptome+DNA #Methylome Glucose-6-phosphate dehydrogenase/G6PD S188F CRISPR rat vs WT 1509 DEG->⏫DNMT1/2, TET2/3-> ⏫5-hmC ie.⏬global DNA methylation 4222 differentially methylated regions -> 29 hypomethylated + ⏫genes-> Lipid/ROS/Thermogenesis www.mdpi.com/1422-0067/24...
神経・代謝疾患におけるレプチンの生理・作用機序に関する知見の最新動向 「レプチン作用の分子機構とその病態における役割に関する最近の進歩を紹介し、このアディポカインの作用が損なわれている可能性のある疾患の治療のための新しいアプローチを」 Molecular Sciences https://t.co/0h54cXpxqg
#Neurocovid #SARSCoV2 Infection and Dysregulation of Dopamine Neurotransmission
This video explains the leptin hormone, a peptide produced mainly in fat tissue, which serves as a long-term indicator of energy reserves. It details how leptin influences appetite regulation via brain receptors and its…
This video explains the hormone leptin, its function in regulating satiety, and the mechanisms of leptin resistance. It discusses how obesity impacts leptin activity and why supplementation often fails in common cases…
www.mdpi.com/2076-3425/13... www.mdpi.com/1422-0067/24... www.researchgate.net/profile/Xian... journals.viamedica.pl/neurologia_n... mdpi-res.com/d_attachment...
Interesting #Aorta Transcriptome+DNA #Methylome Glucose-6-phosphate dehydrogenase/G6PD S188F CRISPR rat vs WT 1509 DEG->⏫DNMT1/2, TET2/3-> ⏫5-hmC ie.⏬global DNA methylation 4222 differentially methylated regions -> 29 hypomethylated + ⏫genes-> Lipid/ROS/Thermogenesis www.mdpi.com/1422-0067/24...
#SpatialTranscriptomics #GeoMx @nanostringtech #HypertrophicCardiomyopathy 4 Cases+2 Ctrls, 72 ROIs 1800 transcripts Focal myocyte disarray showing IFN signaling & mito & ECM perturbations CD99 signaling b/w cardiomyocytes!?
Possible Pathogenesis and Prevention of Long COVID: SARS-CoV-2-Induced Mitochondrial Disorder
Retroviruses are trending, another interesting article by an italian team about COVID-19 News: SARS-CoV-2 Reactivation Of Human Endogenous Retroviruses Contributes To Kawasaki Disease, MIS-C And Even COVID-19 Severity! www.thailandmedical.news/news/covid-1... www.mdpi.com/1422-0067/24...
#Neurocovid #SARSCoV2 Infection and Dysregulation of Dopamine Neurotransmission
#Neurocovid #SARSCoV2 Infection and Dysregulation of Dopamine Neurotransmission
神経・代謝疾患におけるレプチンの生理・作用機序に関する知見の最新動向 「レプチン作用の分子機構とその病態における役割に関する最近の進歩を紹介し、このアディポカインの作用が損なわれている可能性のある疾患の治療のための新しいアプローチを」 Molecular Sciences https://t.co/0h54cXpxqg
The Role of Fecal Microbiota Transplantation in the Treatment of Neurodegenerative Diseases: A Review https://www.mdpi.com/1422-0067/24/2/1001