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Bioeng Transl Med January 2023 PMID 36684083

Alzheimer's and Parkinson's disease therapies in the clinic.

Puja Chopade, Neha Chopade, Zongmin Zhao, Samir Mitragotri, Rick Liao, Vineeth Chandran Suja

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Mentions

3
Peak: 1 in Sep 2022
across 3 sources since Sep 2022

Extended reach

178
potential audience

Total likes

9

Video views

69

Mentions per month

Sep 2022 – Apr 2023

Where it's discussed

  • X / Twitter1 posts
  • YouTube1 videos
  • News1 articles

AI synopsis

What people are saying

The discussion emphasizes the ongoing controversy and challenges in Alzheimer’s research, with phrases like 'embroiled in controversy' and noting the lack of a cure, which reflect skepticism or frustration. The tone is somewhat reflective, suggesting interest but not deep engagement with the technical details of the article.

AgreementNeither agree nor disagree

The discussion shows mixed reactions, with some acknowledgment of ongoing challenges but no strong consensus.

InterestModerate interest

The mention of World Alzheimer’s Day and curiosity about current research indicates moderate interest.

EngagementNeutral engagement

The comments are somewhat superficial, primarily sharing opinions or highlighting the topic without deep analysis.

ImpactNeutral impact

The overall exchange reflects awareness rather than discussion of significant breakthroughs or implications.

Abstract in brief

  • The article reviews current therapeutic strategies for Alzheimer's and Parkinson's diseases, highlighting past and ongoing clinical trials, and noting that most treatments now focus on slowing disease progression rather than curing it.
  • It emphasizes a shift from therapies that mainly provide symptomatic relief through neurotransmitter targeting to those that address underlying causes like inflammation, oxidative stress, and protein aggregation, along with the underutilization of delivery methods for biologic treatments.
  • The review also discusses emerging preclinical approaches and analyzes clinical success rates, aiming to inform future research and improve therapeutic development for these major neurodegenerative diseases.
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Top posts

Most liked on X and Bluesky
Vineeth 'Vinny' Chandran Suja, PhD
@VinnySuja · X

Today is World Alzheimer’s day. Nearly 121 years after the first clinical diagnosis, Alzheimer’s research is embroiled in controversy, and we are yet to find a tenable cure. Curious what the current clinical landscape is? Check out this paper from - https://t.co/AGuwW5nXT2

Sep 21, 2022 · 8 likes · 99 followers View post →

All mentions

Vineeth 'Vinny' Chandran Suja, PhD
@VinnySuja · X

Today is World Alzheimer’s day. Nearly 121 years after the first clinical diagnosis, Alzheimer’s research is embroiled in controversy, and we are yet to find a tenable cure. Curious what the current clinical landscape is? Check out this paper from - https://t.co/AGuwW5nXT2

Sep 21, 2022 · 8 likes · 99 followers View post →
Fnmol 1 1431079 | PDF | Microglia | Protein Folding
News

doi: 10.1002/JLB.MR0718-299R and galectin-4 in the idiopatic Parkinson ... 6, 65–74. 8:e10367. doi: 10.1002/btm2.10367 doi: 10.2741/S415 Chung, C. G. ...

Dec 16, 2025 View →