February 2023 PMID 36702997

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

Ditte Demontis, G Bragi Walters, Georgios Athanasiadis, Raymond Walters, Karen Therrien, Trine Tollerup Nielsen, Leila Farajzadeh, Georgios Voloudakis, Jaroslav Bendl, Biau Zeng, Wen Zhang, Jakob Grove, Thomas D Als, Jinjie Duan, F Kyle Satterstrom

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Mentions

145
Peak: 53 in Jan 2023
across 7 sources since Feb 2022

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Total likes

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Feb 2022 – Jan 2026

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AI synopsis

What people are saying

Several discussions demonstrate strong interest and recognition of the research's importance, with phrases like 'refine the genetic architecture' and 'implicate several cognitive domains,' showing appreciation for the depth of findings. The tone is generally professional and enthusiastic, emphasizing the study's relevance to ongoing ADHD research and genetic analysis.

AgreementModerate agreement

Most discussions acknowledge the significance of the study, highlighting the discovery of 27 risk loci and their implications, indicating general support for the research's findings.

InterestHigh interest

Posts show high interest, with many referencing detailed aspects of the study, such as its methodology and relevance to ADHD genetics.

EngagementModerate engagement

Comments reflect moderate engagement, including sharing of the publication, discussing its implications, and requesting access to the full article, suggesting an active but not overly deep discussion.

ImpactHigh impact

The collective tone suggests the publication could have considerable influence in the field, as many participants refer to its groundbreaking nature and potential for future research.

Abstract in brief

  • ADHD is a common neurodevelopmental disorder with a strong genetic basis, as shown in a large study involving 38,691 individuals with the disorder compared to 186,843 controls.
  • Researchers found 27 significant genomic regions linked to ADHD, with many genes related to early brain development and certain brain cell types, suggesting a biological basis for the disorder.
  • The study also highlighted that many genetic factors influencing ADHD overlap with other psychiatric conditions and are correlated with cognitive challenges, particularly in areas like attention and reasoning.

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Nature Genetics
@NatureGenet · X

Jan 26, 2023 · 124 likes · 42 shares · 127,811 followers View post →
Neuroscience News
@NeuroscienceNew · X

“Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains” by Ditte Demontis et al. Nature Genetics https://t.co/EPsvEvvhag

Feb 9, 2023 · 17 likes · 4 shares · 506,557 followers View post →
Samuele Cortese
@CorteseSamuele · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive… https://t.co/H7FZnCIVum

Jan 27, 2023 · 12 likes · 5 shares · 4,076 followers View post →
GWAS_lit
@GWAS_lit · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains https://t.co/f8rEXDeJRD https://t.co/waHz7KaqSX

Feb 16, 2022 · 6 likes · 3 shares · 5,943 followers View post →
Federació Catalana TDAH
@FcafaT · X

Metaanàlisi d'estudi d'associació. 38.691 persones amb TDAH i 186.843 controls. Les anàlisis de tot el genoma del TDAH identifiquen 27 loci de risc, refinen l'arquitectura genètica i impliquen diversos dominis cognitius. https://t.co/7FjMfDMbcw

Jan 27, 2023 · 5 likes · 3 shares · 1,253 followers View post →
medRxiv
@medrxivpreprint · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains https://t.co/izkeYo5m52 #medRxiv

Feb 16, 2022 · 4 likes · 17,440 followers View post →

All mentions

Amy Gillespie
@DrAmyGillespie · X

In the #BAP2024 guest lecture on ADHD, this is illustrated by the shift from studies of <50 families a couple decades ago ➡️ last year published genome wide association study with 38k cases (https://t.co/LorpU9wiaU) ➡️ currently working on the latest analysis of 140k cases!

Jul 22, 2024 · 1 like · 1,244 followers View post →
まつもとメンタルクリニック
@XK2FLqSFYhE6flp · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains | Nature Genetics https://t.co/a5njgV3WWd

Nov 5, 2023 · 2 likes · 3,679 followers View post →
Felipè
@fill6020 · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains DOI: https://t.co/zL2CVHcUyi Many thanks to anyone who has access and can share :) #ICanHazPDF

Jun 6, 2023 · 1 like · 26 followers View post →
Anders Børglum
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RT @NeuroscienceNew: “Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive d…

May 19, 2023 · 4 shares · 278 followers View post →
Prof Marios Adamou OBE
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Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains | Nature Genetics https://t.co/TUOYu50Odu

May 13, 2023 · 1,013 followers View post →
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RT @NeuroscienceNew: “Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive d…

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Booranaa fi Bareentuu
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RT @DrImranSheikh: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive doma…

Feb 10, 2023 · 1 share · 2,156 followers View post →
Dr Imran Sheikh
@DrImranSheikh · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains https://t.co/BCVyJhafA3 https://t.co/29CHf9ryxk

Feb 10, 2023 · 1 like · 1 share · 24,083 followers View post →
Lumosa Therapeutics
@lumosa_tx · X

Original research: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains https://t.co/o443xRDZBa Share if you like this article, follow Lumosa for more topics like this.

Feb 10, 2023 · 215 followers View post →
Countee
@viveinelouise · X

RT @NeuroscienceNew: “Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive d…

Feb 9, 2023 · 4 shares · 65 followers View post →
Hemaraja Nayaka. S
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RT @NeuroscienceNew: “Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive d…

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ARYAN®
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RT @NeuroscienceNew: “Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive d…

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Neuroscience News
@NeuroscienceNew · X

“Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains” by Ditte Demontis et al. Nature Genetics https://t.co/EPsvEvvhag

Feb 9, 2023 · 17 likes · 4 shares · 506,557 followers View post →
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ADHD Remote Technology (ART) KCL
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Bioinformatics Trends 
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RT @OmicsNL: “Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains”,…

Jan 30, 2023 · 1 share · 8,210 followers View post →
X-omics
@OmicsNL · X

“Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains”, published in @NatureGenet. New work from Dorret Boomsma et al. https://t.co/C6r74KcKD6 #xomics #GWAS #dataanalysis #ADHD

Jan 30, 2023 · 4 likes · 1 share · 185 followers View post →
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the paper link
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Trend new: Demontis D, ..., Børglum AD (Nat Genet) __Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains__ https://t.co/WFktlncJH6

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RT @CorteseSamuele: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive… ht…

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RT @FcafaT: Metaanàlisi d'estudi d'associació. 38.691 persones amb TDAH i 186.843 controls. Les anàlisis de tot el genoma del TDAH identifi…

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RT @CorteseSamuele: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive… ht…

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Dopaminien
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RT @CorteseSamuele: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive… ht…

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RT @FcafaT: Metaanàlisi d'estudi d'associació. 38.691 persones amb TDAH i 186.843 controls. Les anàlisis de tot el genoma del TDAH identifi…

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Tenemos TDAH SBD
@TenemosTDAHSBD · X

RT @FcafaT: Metaanàlisi d'estudi d'associació. 38.691 persones amb TDAH i 186.843 controls. Les anàlisis de tot el genoma del TDAH identifi…

Jan 27, 2023 · 3 shares · 1,140 followers View post →
Federació Catalana TDAH
@FcafaT · X

Metaanàlisi d'estudi d'associació. 38.691 persones amb TDAH i 186.843 controls. Les anàlisis de tot el genoma del TDAH identifiquen 27 loci de risc, refinen l'arquitectura genètica i impliquen diversos dominis cognitius. https://t.co/7FjMfDMbcw

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Samuele Cortese
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Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive… https://t.co/H7FZnCIVum

Jan 27, 2023 · 12 likes · 5 shares · 4,076 followers View post →
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Nature Genetics
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Jan 26, 2023 · 124 likes · 42 shares · 127,811 followers View post →
Ammy Pan
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RT @GWAS_lit: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains h…

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BibliotecaHUVH
@BibliotecaHUVH · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains https://t.co/eaij4lmKyd [preprint] @medrxivpreprint

Feb 18, 2022 · 2,309 followers View post →
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@Coco_Lucho2 · X

RT @GWAS_lit: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains h…

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RT @GWAS_lit: Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains h…

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GWAS_lit
@GWAS_lit · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains https://t.co/f8rEXDeJRD https://t.co/waHz7KaqSX

Feb 16, 2022 · 6 likes · 3 shares · 5,943 followers View post →
medRxiv
@medrxivpreprint · X

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains https://t.co/izkeYo5m52 #medRxiv

Feb 16, 2022 · 4 likes · 17,440 followers View post →
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Is ADHD Genetic? Exploring the Link to Genetics. Discover the truth about the genetic component of ADHD and whether it's always inherited.

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637 Likes, 8 Comments. TikTok video from Brain.curiosities , PhD (. 21.1K1w ago.

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GENY : DOI: 10.1038/s41588-022-01285-8. DOI: [10.1038/s41588-018-0269-7](https://doi.org/10.1038/s41588-018-0269-7). dźwięk oryginalny ...

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GENY : DOI: 10.1038/s41588-022-01285-8. DOI: [10.1038/s41588-018-0269-7](https://doi.org/10.1038/s41588-018-0269-7). dźwięk oryginalny ...

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org/10.1038/s41588-022-01285-8 Grimm, O., Kranz, T. M., & Reif, A. (2022). Genetics of ADHD: What should the clinician know? Frontiers in ...

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org/10.1038/s41588-022-01285-8. nature.com. Genome-wide analyses of ADHD identify 27 risk loci,. 9 mos. Profile photo of Helle. Helle Rytter ...

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[Article] Genome-wide analyses of ADHD identify 27 risk loci, refine ...
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DOI: https://doi.org/10.1038/s41588-022-01285-8 Link: https://www.nature.com/articles/s41588-022-01285-8#citeas Authors: Demontis, D., ...

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GENY : DOI: 10.1038/s41588-022-01285-8. DOI: [10.1038/s41588-018-0269-7](https://doi.org/10.1038/s41588-018-0269-7). dźwięk oryginalny ...

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https://doi.org/10.1038/s41588-022-01285-8. My colleagues just published a very interesting paper on different ways how genetic risk of ADHD ...

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Сколько интересных вещей известно о генетике СДВГ? : r/genetics
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https://doi.org/10.1038/s41588-022-01285-8. Мои коллеги только что опубликовали очень интересную статью о различных способах передачи ...

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Novas perspectivas sobre a origem e o tratamento do TDAH ...
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... 10.1038/s41588-022-01285-8" target="_blank" rel="noopener">Nature Genetics que identificou 76 genes potencialmente relacionados ...

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org/10.1038/s41588-022-01285-8. 打赏. First slide 绘谱学堂| 病从口入--胆汁酸颠覆IBD新机制>> · First slide 「大小鼠繁育与健康管理」指导海报,点击 ...

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Researchers link 27 genetic variants to ADHD | ScienceDaily
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Nature Genetics, 2023; DOI: 10.1038/s41588-022-01285-8. Cite This Page: MLA; APA; Chicago. Aarhus University. "Researchers link 27 genetic ...

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Researchers link 27 genetic variants to ADHD
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DOI: 10.1038/s41588-022-01285-8. Journal information: Nature Genetics. Key medical concepts. Attention Deficit Hyperactivity Disorder ...

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Researchers identify 27 genetic risk variants related to ADHD
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doi.org/10.1038/s41588-022-01285-8. Currently rated 4.2 by 6 people. Posted in: Genomics | Medical Condition News. Comments (0). Download PDF ...

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[Article] Genome-wide analyses of ADHD identify 27 risk loci, refine ...
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Nat Genet (2023). DOI: https://doi.org/10.1038/s41588-022-01285-8. URL: https://doi.org/10.1038/s41588-022-01285-8. Upvote 1. Downvote

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... 10.1038/s41588-022-01285-8. 注意欠如・多動性障害(ADHD)は、よく見られる神経発達障害で、遺伝的要因の関与が大きい。本論文では、ADHDの3万8691人 ...

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