Sci Rep February 2023 PMID 36797393

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial.

Takeshi Katayoshi, Sachi Uehata, Noe Nakashima, Takahisa Nakajo, Natsuko Kitajima, Masakatsu Kageyama, Kentaro Tsuji-Naito

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Mentions

22
Peak: 5 in Feb 2023
across 6 sources since Feb 2023

Extended reach

413,583
potential audience

Total likes

6,807

Video views

363,926

Mentions per month

Feb 2023 – May 2025

Where it's discussed

  • X / Twitter6 posts
  • News6 articles
  • YouTube3 videos
  • Blogs3 articles
  • Facebook2 posts
  • Reddit2 posts

AI synopsis

What people are saying

Discussions highlight the study's key conclusion that long-term NMN supplementation did not significantly affect arterial stiffness, as expressed through neutral language like 'no significant results' and simple references to the study's methodology. The tone is factual and restrained, reflecting moderate interest and engagement, with minimal debate on broader implications.

AgreementNeither agree nor disagree

Most discussions acknowledge the study's findings, noting the lack of significant effects on arterial stiffness, indicating general consensus or neutrality.

InterestModerate interest

The discussions show modest interest, mainly noting the study's findings without deep exploration or skepticism.

EngagementModerate engagement

Comments reference specific aspects like the methodology and results, showing some level of engagement, but without active debate or detailed analysis.

ImpactNeutral impact

Participants seem aware of the study's implications but do not perceive it as having a groundbreaking impact on the field.

Abstract in brief

  • This study tested whether taking NMN, a supplement that boosts NAD levels, for 12 weeks can improve health markers in middle-aged adults.
  • It found that NMN increased some NAD-related compounds in the blood and showed a trend toward reducing arterial stiffness, but the change in stiffness wasn’t statistically significant.
  • Overall, taking NMN was safe, well-tolerated, and may have potential benefits for cardiovascular health, especially regarding arterial stiffness.]

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial https://t.co/Xx9SyZj2nQ @SciReports #NMN https://t.co/DSENjo1AkN

Feb 17, 2023 · 19 likes · 2 shares · 41,316 followers View post →
DrRPalmquist
@DrPalmquist · X

RT @agingdoc1: Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementat…

Feb 18, 2023 · 2 shares · 3,158 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial https://t.co/S3OZcfkqzr

Feb 18, 2023 · 2,239 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial https://t.co/sLyB7F7DD3

Feb 21, 2023 · 2,239 followers View post →
Orlando_uy
@Orlando_uy · X

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial. No significant results on arterial stiffness. https://t.co/j0QwZEVREW

Mar 1, 2023 · 690 followers View post →
humberto
@humbertoayca24 · X

RT @agingdoc1: Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementat…

Feb 20, 2023 · 2 shares · 4 followers View post →

All mentions

Orlando_uy
@Orlando_uy · X

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial. No significant results on arterial stiffness. https://t.co/j0QwZEVREW

Mar 1, 2023 · 690 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial https://t.co/sLyB7F7DD3

Feb 21, 2023 · 2,239 followers View post →
humberto
@humbertoayca24 · X

RT @agingdoc1: Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementat…

Feb 20, 2023 · 2 shares · 4 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial https://t.co/S3OZcfkqzr

Feb 18, 2023 · 2,239 followers View post →
DrRPalmquist
@DrPalmquist · X

RT @agingdoc1: Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementat…

Feb 18, 2023 · 2 shares · 3,158 followers View post →
Agingdoc
@agingdoc1 · X

Nicotinamide adenine dinucleotide metabolism and arterial stiffness after long-term nicotinamide mononucleotide supplementation: a randomized, double-blind, placebo-controlled trial https://t.co/Xx9SyZj2nQ @SciReports #NMN https://t.co/DSENjo1AkN

Feb 17, 2023 · 19 likes · 2 shares · 41,316 followers View post →