PubHawk
Chin Med J (Engl) February 2023 PMID 36848180

Integrins in human hepatocellular carcinoma tumorigenesis and therapy.

Qiong Gao, Zhaolin Sun, Deyu Fang

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Mentions

4
Peak: 1 in Feb 2023
across 3 sources since Feb 2023

Extended reach

1,215
potential audience

Total likes

1

Video views

120

Mentions per month

Feb 2023 – Aug 2023

Where it's discussed

  • X / Twitter2 posts
  • YouTube1 videos
  • News1 articles

AI synopsis

What people are saying

The discussions reflect a generally positive attitude, with comments such as 'integrins could be a game changer' and references to ongoing research into targeted drugs, showing excitement about possible new therapies. The tone and choice of words like 'promising' and 'critical' emphasize the perceived significance of the article's findings in advancing cancer treatment.

AgreementModerate agreement

Most discussions acknowledge the importance of integrins in HCC and support the potential of targeting them for therapy.

InterestHigh interest

Posts show high curiosity about new treatment avenues, referencing clinical and preclinical research with enthusiasm.

EngagementModerate engagement

Participants discuss mechanisms like cell adhesion and signaling, indicating some depth in their engagement, though not deeply technical.

ImpactModerate impact

Several posts highlight the relevance of this research for future HCC treatments, suggesting moderate perceived impact.

Abstract in brief

  • Integrins are transmembrane receptors that connect the extracellular matrix to the cell's internal skeleton and play a key role in cell adhesion, migration, signaling, and gene regulation, impacting tumor growth and spread.
  • The review highlights how abnormal integrin expression and activation contribute to liver cancer (Hepatocellular Carcinoma, HCC), influencing not only cancer cells but also other cells within the tumor environment, with special attention to hepatitis B virus-related HCC.
  • It also summarizes current clinical and preclinical research on drugs targeting integrins as potential therapies for HCC, emphasizing their promise as anti-tumor treatments.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Phage Papers
@Phage_Papers · X

Integrins in human hepatocellular carcinoma tumorigenesis and therapy https://t.co/FE826qrBdm

Feb 27, 2023 · 645 followers View post →
CMJ
@ChinMedJ · X

Integrins in human hepatocellular carcinoma tumorigenesis and therapy https://t.co/gRp3gPliR6

Aug 15, 2023 · 440 followers View post →

All mentions

CMJ
@ChinMedJ · X

Integrins in human hepatocellular carcinoma tumorigenesis and therapy https://t.co/gRp3gPliR6

Aug 15, 2023 · 440 followers View post →
Phage Papers
@Phage_Papers · X

Integrins in human hepatocellular carcinoma tumorigenesis and therapy https://t.co/FE826qrBdm

Feb 27, 2023 · 645 followers View post →
Researchers review the role of integrins in human hepatocellular ...
News

DOI: https://doi.org/10.1097/CM9.0000000000002459. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases ...

May 10, 2023 View →