Automating iPSC generation to enable autologous photoreceptor cell replacement therapy.

Laura R Bohrer, Nicholas E Stone, Nathaniel K Mullin, Andrew P Voigt, Kristin R Anfinson, Jessica L Fick, Viviane Luangphakdy, Bradley Hittle, Kimerly Powell, George F Muschler, Robert F Mullins, Edwin M Stone, Budd A Tucker

February 2023 J Transl Med

Synopsis of Social media discussions

Participants strongly agree on the promising nature of the automated production of iPSCs, often describing it as a breakthrough for retinal therapy with words like 'scalable,' 'efficient,' and 'game changer.' The tone reflects excitement about how this technology could transform treatment options, demonstrating deep engagement and recognition of its high impact.

A
Agreement
 Strong agreement

Most discussions express strong support and enthusiasm for the technological advances described, emphasizing the importance of automation and its potential benefits.

I
Interest
 High level of interest

The discussions demonstrate high interest, with multiple mentions of innovative tools like the robotic platform Cell X and its role in personalized medicine.

E
Engagement
 High engagement

Posts include technical details about the platform, its scalability, and the implications for retinal therapy, showing deep engagement with the subject.

I
Impact
 High level of impact

The consensus highlights the significant potential of this automation to revolutionize personalized therapy for incurable vision loss, indicating high perceived impact.

Social Mentions

YouTube

1 Videos

Twitter

17 Posts

Metrics

Video Views

14

Total Likes

43

Extended Reach

29,653

Social Features

18

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

  • Esti Halperin
    @EstiHalperin (Twitter)

    RT @curechm: Automating #iPSC generation to enable autologous photoreceptor cell replacement therapy https://t.co/OGAgbj9Lth
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    March 12, 2023

    5

  • naama
    @naama_goldman (Twitter)

    RT @curechm: Automating #iPSC generation to enable autologous photoreceptor cell replacement therapy https://t.co/OGAgbj9Lth
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    March 10, 2023

    5

  • Sean Hart, PhD
    @SeanJHart (Twitter)

    RT @LumaCyte: Researchers have developed a robotic platform, Cell X, that enables parallel production of clinical-grade #iPSCs for autologo…
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    March 8, 2023

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    March 7, 2023

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  • LumaCyte
    @LumaCyte (Twitter)

    Researchers have developed a robotic platform, Cell X, that enables parallel production of clinical-grade #iPSCs for autologous retinal #cell replacement. This platform is a scalable & efficient method for #producing quality photoreceptor precursor cells. https://t.co/wZn8ULpi9c
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    March 7, 2023

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  • Simplesmente Edu
    @eddiedipiero (Twitter)

    RT @curechm: Automating #iPSC generation to enable autologous photoreceptor cell replacement therapy https://t.co/OGAgbj9Lth
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    March 2, 2023

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  • thereishope66
    @thereishope66 (Twitter)

    RT @curechm: Automating #iPSC generation to enable autologous photoreceptor cell replacement therapy https://t.co/OGAgbj9Lth
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    March 2, 2023

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  • NeuroStemCells
    @NeuroStemCell (Twitter)

    Automating iPSC generation to enable autologous photoreceptor cell replacement therapy https://t.co/kt1dTvC3x0
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    March 2, 2023

  • Fayez Al Mutairi
    @ffayezz (Twitter)

    RT @curechm: Automating #iPSC generation to enable autologous photoreceptor cell replacement therapy https://t.co/OGAgbj9Lth
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    March 1, 2023

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  • CureCHM
    @curechm (Twitter)

    Automating #iPSC generation to enable autologous photoreceptor cell replacement therapy https://t.co/OGAgbj9Lth
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    March 1, 2023

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Abstract Synopsis

  • The study describes using a robotic platform called Cell X within a sterile environment to efficiently produce patient-specific induced pluripotent stem cells (iPSCs) for retinal therapy, overcoming previous manufacturing hurdles.
  • The iPSCs generated with this system were confirmed to be healthy, genetically stable, and capable of forming retinal organoids that are functionally similar to those created manually, ensuring quality and consistency.
  • This innovative automated method paves the way for large-scale, clinical-grade production of retinal cells, making personalized photoreceptor cell replacement therapy more feasible for treating incurable vision loss caused by inherited retinal degeneration.]