Nat Commun March 2023 PMID 36864029

Population-level impacts of antibiotic usage on the human gut microbiome.

Kihyun Lee, Sebastien Raguideau, Kimmo Sirén, Francesco Asnicar, Fabio Cumbo, Falk Hildebrand, Nicola Segata, Chang-Jun Cha, Christopher Quince

Mentions

116
Peak: 47 in Mar 2023
across 6 sources since Mar 2023

Extended reach

293,347
potential audience

Total likes

144

Video views

21

Mentions per month

Mar 2023 – Jun 2025

Where it's discussed

  • X / Twitter75 posts
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  • Facebook3 posts
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AI synopsis

What people are saying

Several discussions highlight the core findings of the study, with users noting that increased antibiotic usage correlates with higher levels of antimicrobial resistance genes. Phrases like 'really important study' and 'fascinating stuff' illustrate the enthusiasm and seriousness with which participants view the implications of the research. The tone ranges from optimistic curiosity to cautious concern, particularly regarding the reliability of data from large databases.

AgreementModerate agreement

The majority of discussions show support for the findings presented in the publication, indicating a consensus on the importance of studying antibiotic usage.

InterestHigh interest

Participants demonstrate a high level of curiosity regarding the implications of the research, with many expressing fascination.

EngagementModerate engagement

Some comments reflect on the methodology and outcomes, although many posts are more focused on broad ideas rather than in-depth analysis.

ImpactHigh impact

Many participants perceive the findings as significantly impactful for public health and the understanding of antimicrobial resistance.

Abstract in brief

  • The extensive use of antibiotics contributes to the evolution and spread of antimicrobial resistance genes (ARGs) among pathogenic microbes, but its effect on the human gut microbiome requires further investigation.
  • A large study of gut microbiomes from healthy individuals not using antibiotics reveals significant correlations between ARG abundance and antibiotic usage rates across multiple countries, with samples from China showing unique patterns.
  • Analysis of shared ARGs across various microbial species indicates that resistance patterns in the gut microbiome can be categorized into two types, with one type exhibiting higher ARG abundance linked to specific resistance genes in certain bacteria.

Top posts

Most liked on X and Bluesky
Wiep Klaas Smits
@SmitsLab · X

Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly significant correlations between both the total ARG abundance and diversity and per capita antibiotic usage rates...

Mar 6, 2023 · 67 likes · 34 shares · 2,357 followers View post →
NCAS_Australia
@NCAS_Aus · X

This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance genes being passed around… Population-level impacts of antibiotic usage on the human gut microbiome | Nature Communications https://t.co/Tp5hbvm6TZ

Apr 9, 2023 · 50 likes · 27 shares · 3,801 followers View post →
Reiner 
@erlesen · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrobial resistance (AMR) by human pathogens is well-established as one of the most serious current and developing threats to human health @_atanas_

Mar 3, 2023 · 23 likes · 14 shares · 7,855 followers View post →
Becky Smith
@rlsdvm.bsky.social · Bluesky

111/250 is Population-level impacts of antibiotic usage on the human gut microbiome Really fascinating stuff here, although I always worry about these massive databases being properly annotated and unbiased

Jun 13, 2025 · 2 likes · 1 share View post →
AntibioticResistance
@AntibioticResis · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/UntwYiXthF

Mar 3, 2023 · 1 like · 1 share · 13,384 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 123,624 followers View post →

All mentions

Becky Smith
@rlsdvm.bsky.social · Bluesky

111/250 is Population-level impacts of antibiotic usage on the human gut microbiome Really fascinating stuff here, although I always worry about these massive databases being properly annotated and unbiased

Jun 13, 2025 · 2 likes · 1 share View post →
Sehyun Oh
@drsehyun · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/b5HJQNwgsQ

Dec 21, 2023 · 191 followers View post →
reMAY(^^ゞ
@remay4SGR · X

(-_-;) < Population-level impacts of antibiotic usage on the human gut microbiome | Nature Communications https://t.co/OKtVEdPlFS

May 8, 2023 · 444 followers View post →
Mirada Profesional
@MiradaPF · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/mlDnnCvkRX

May 5, 2023 · 322 followers View post →
HealthyBuilds
@HealthyBuilds · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/AHZyPfJ1Wo

Apr 28, 2023 · 197 followers View post →
Tim Nyap Ming
@NyapMingTim · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 21, 2023 · 27 shares · 498 followers View post →
Lesley Hawes MPH, PhD
@lesleyhawes4 · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 12, 2023 · 27 shares · 710 followers View post →
Catherine Sherwin PhD, MD, MPharm, FCP, FAAPS
@CathMSherwin1 · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 10, 2023 · 27 shares · 285 followers View post →
Carl Kirkpatrick
@CarlkRx · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 10, 2023 · 27 shares · 1,899 followers View post →
Heather Amato, PhD
@HeatherKAmato · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 10, 2023 · 27 shares · 165 followers View post →
Sid Chopra
@skchopra007 · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 10, 2023 · 27 shares · 940 followers View post →
Rasidah Senian
@Rasidah · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 10, 2023 · 27 shares · 98 followers View post →
Luis Escosa Garcia
@LuisEscosa · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 10, 2023 · 27 shares · 776 followers View post →
Jon Otter
@jonotter · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 10, 2023 · 27 shares · 8,776 followers View post →
Roland Freimüller MSc.
@Roland_F_MSc · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 10, 2023 · 27 shares · 1,495 followers View post →
Patrick Harris
@padstamundo · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 2,782 followers View post →
Tilak Ramanaidu
@TilakbabuR · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 332 followers View post →
Colleen Naughton, PhD. (she\her\hers)
@naughtoncc · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 4,208 followers View post →
ACIPC
@ACIPC · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 1,867 followers View post →
Blake Nield
@MADTurnUP · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 186 followers View post →
Michael Wagner
@MichiWagner4 · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 12,528 followers View post →
Merve Tepe, PhD
@mervetepePhD · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 1,153 followers View post →
David Patrick
@DavidPatrickMD · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 819 followers View post →
henggee
@henggee77 · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 67 followers View post →
Desire Gil Perez
@DesireGilPerez1 · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 22 followers View post →
pepper_min
@peppermin5 · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 841 followers View post →
Justin Moore
@moore_wjustin · X

RT @NCAS_Aus: This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance…

Apr 9, 2023 · 27 shares · 1,846 followers View post →
NCAS_Australia
@NCAS_Aus · X

This is a really important study. Authors studied 14 countries. Basically the more antimicrobial use, the more AMR resistance genes being passed around… Population-level impacts of antibiotic usage on the human gut microbiome | Nature Communications https://t.co/Tp5hbvm6TZ

Apr 9, 2023 · 50 likes · 27 shares · 3,801 followers View post →
Animalcules
@bacteriophile · X

Population-level impacts of antibiotic usage on the human gut microbiome... https://t.co/Y56va1mcVS

Apr 4, 2023 · 520 followers View post →
Enas Newire
@EnasNewire · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 22, 2023 · 34 shares · 195 followers View post →
Gemstone
@Alease09698564 · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 17, 2023 · 34 shares · 60 followers View post →
Sergio Castañeda
@scastanedag1 · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 7, 2023 · 34 shares · 656 followers View post →
Lizzy Rosser
@bcells_rosser · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 7, 2023 · 34 shares · 724 followers View post →
Thinking Autism
@TweetingAutism · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 7, 2023 · 34 shares · 14,330 followers View post →
Ffion Hammond
@ffionruth · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 7, 2023 · 34 shares · 415 followers View post →
John Li
@JohnLi65359628 · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 7, 2023 · 34 shares · 84 followers View post →
Microbiome Research Centre
@MRC_microbiome · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 7, 2023 · 34 shares · 2,914 followers View post →
Sid Chopra
@skchopra007 · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 7, 2023 · 34 shares · 940 followers View post →
Yuliaxis
@YuliaxisRC · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 575 followers View post →
A persistent organism
@DrMarwa_Hassan · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 1,405 followers View post →
Michelle Fitzmaurice
@DrMFitzmaurice · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 761 followers View post →
Petro Karungamye
@KarungamyePetro · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 232 followers View post →
Derek Weber
@dknice · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 93 followers View post →
Eduardo Villalobo
@ptu_us_es · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 1,110 followers View post →
Scott Anderson
@Psychobiotic · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 18,565 followers View post →
Ruben Kenny Briceno
@rubskenny · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 270 followers View post →
✌
@Iamatewo1 · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 401 followers View post →
Ann Gregory, PhD
@gregory_annc · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 1,591 followers View post →
Emad El-Omar
@emadelomar · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 3,876 followers View post →
Apostolos Liakopoulos
@AposLiakopoulos · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 962 followers View post →
Nicolas Fanget
@nfanget · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 942 followers View post →
Lori L. Burrows
@Dr_Lori_Burrows · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 4,712 followers View post →
Feargal Ryan
@Feargal_Ryan · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 681 followers View post →
Ed Kuijper
@EdKuijper2 · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 915 followers View post →
Changzhi Wang
@WChangzhi · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 157 followers View post →
Jake Robinson
@_jake_robinson · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 3,662 followers View post →
Zamin Iqbal
@ZaminIqbal · X

RT @SmitsLab: Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly si…

Mar 6, 2023 · 34 shares · 9,490 followers View post →
Wiep Klaas Smits
@SmitsLab · X

Population-level impacts of antibiotic usage on the human gut microbiome - @NatureComms https://t.co/OMuCQF122s ...highly significant correlations between both the total ARG abundance and diversity and per capita antibiotic usage rates...

Mar 6, 2023 · 67 likes · 34 shares · 2,357 followers View post →
Europe PMC articles
@EuropePMC · X

New from #BBSRC https://t.co/TJy75VWwGz Population-level impacts of antibiotic usage on the human gut microbiome.

Mar 5, 2023 · 1,552 followers View post →
Europe PMC articles
@EuropePMC · X

New from #ERC_Research https://t.co/TJy75VWwGz Population-level impacts of antibiotic usage on the human gut microbiome.

Mar 5, 2023 · 1,552 followers View post →
Kelly Bachta
@kelly_bachta · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 5, 2023 · 14 shares · 488 followers View post →
Andrea McBeth
@DreMcBeth · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 5, 2023 · 14 shares · 263 followers View post →
Apostolos Liakopoulos
@AposLiakopoulos · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 5, 2023 · 14 shares · 962 followers View post →
Heather McEwen
@HeatherMcEwen3 · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 1,406 followers View post →
Vincent Touquet
@vinstar · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 1,111 followers View post →
what about boys!
@Romeo_Hotel_ · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 71 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 123,624 followers View post →
Science Communication
@ScienceCommuni2 · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 2,872 followers View post →
Pat
@Hlth_News · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 698 followers View post →
Merisa Cenanovic
@MerisaCenanovic · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 961 followers View post →
Dr. Joy Odimegwu
@Nwauka · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 1,320 followers View post →
Digital Health and Patient Safety Platform
@DHPSP · X

RT @erlesen: Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrob…

Mar 4, 2023 · 14 shares · 6,748 followers View post →
Reiner 
@erlesen · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/n3MmRSoZ4Y The acquisition of antimicrobial resistance (AMR) by human pathogens is well-established as one of the most serious current and developing threats to human health @_atanas_

Mar 3, 2023 · 23 likes · 14 shares · 7,855 followers View post →
AntibioticResistance
@AntibioticResis · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/UntwYiXthF

Mar 3, 2023 · 1 like · 1 share · 13,384 followers View post →
Metagenomics Papers
@metagenomic_lit · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/czvQeMhTqe

Mar 3, 2023 · 3,702 followers View post →
micropapers
@micro_papers · X

Population-level impacts of antibiotic usage on the human gut microbiome https://t.co/MH00iCNv5P

Mar 3, 2023 · 332 followers View post →