March 2023 PMID 36870410

Non-sugar sweeteners and cancer: Toxicological and epidemiological evidence.

Sofia Pavanello, Angelo Moretto, Carlo La Vecchia, Gianfranco Alicandro

Mentions

37
Peak: 16 in Jun 2023
across 8 sources since Jun 2023

Extended reach

33,316
potential audience

Total likes

1,272

Video views

17,696

Mentions per month

Jun 2023 – May 2025

Where it's discussed

  • X / Twitter21 posts
  • News5 articles
  • TikTok4 posts
  • YouTube2 videos
  • Reddit2 posts
  • Bluesky1 posts
  • Facebook1 posts
  • Blogs1 articles

AI synopsis

What people are saying

The overall tone reflects high agreement with scientific findings, as seen in comments like 'There is no evidence showing aspartame causes cancer,' and the mention of systematic reviews. Words such as 'scientific research,' 'evidence,' and 'meta-analyses' highlight a respect for scientific rigor, though some posts also show skepticism about corporate influence and the ongoing debates around the topic.

AgreementStrong agreement

Most discussions align strongly with the article's conclusion that there is no confirmed link between non-sugar sweeteners and cancer.

InterestModerate interest

Participants show moderate interest, as evidenced by references to scientific evidence and regulation, but some mention personal opinions and social discussions which suggest mixed engagement.

EngagementModerate engagement

Many posts reference scientific studies, meta-analyses, and official reports, indicating a fair level of engagement with the evidence.

ImpactModerate impact

While some users emphasize the safety and lack of cancer risk, others point out industry interests and public skepticism, suggesting moderate influence of the publication on perceptions.

Abstract in brief

  • This review analyzes over five decades of toxicological and epidemiological studies on nonsugar sweeteners (NSS) like aspartame, saccharin, steviol glycosides, and others, focusing on their potential link to cancer, and concludes there is no confirmed evidence of a cancer risk from NSS consumption.
  • The toxicological evidence mainly examines genotoxicity and carcinogenicity data, generally indicating that these sweeteners do not pose a significant cancer risk based on laboratory tests and safety evaluations.
  • Most epidemiological studies (cohort and case-control) found no connection between NSS intake and cancers of the bladder, pancreas, or hematopoietic system, with any initial risks observed not being consistently confirmed across different studies.]

Top posts

Most liked on X and Bluesky
Michael Manderville, RD
@Manderville_RD · X

@guardian This is not based on evidence https://t.co/BenAajfnV7

Jun 29, 2023 · 18 likes · 1,316 followers View post →
Amritanshu Rath(he/him/his)
@amritanshu_rath · X

@SynapseDot Aspartame does not cause cancer folks. https://t.co/knCKTqkKWO

Jun 29, 2023 · 4 likes · 163 followers View post →
Marvin H2G2 - Soutien aux scientifiques !
@marvinh2g2.fr · Bluesky

#Santé #Médecine ©️ @lel-media.bsky.social

May 20, 2025 · 4 likes · 1 share View post →
Survivor of the Norwegian butter crisis 2011
@LillianSoe · X

@hasanthehun There is no evidence showing aspartame causes cancer in humans https://t.co/TG6cNXnsBk

Jun 29, 2023 · 2 likes · 1,806 followers View post →
Pathik Joshi
@pathikj80 · X

@coach_ritika Attaching link to a large meta of human studies done on the subject. https://t.co/ImzET1AL0d Having said that, I am not in favour of getting hooked on diet sodas...once in a while seems alright to me.

Jul 2, 2023 · 1 like · 3,350 followers View post →
Eddie
@pussymonious · X

@catale7a I am not referring to his authority, there is real evidence linked in his tweet. Actual Scientific research with tons of references. Nothing GODLY here. Presuming things without evidence is religious thinking, I never do that. https://t.co/4yLqgjHv8n https://t.co/mOpfLsWO5J

Jun 30, 2023 · 1 like · 1 share · 1,792 followers View post →

All mentions

Marvin H2G2 - Soutien aux scientifiques !
@marvinh2g2.fr · Bluesky

#Santé #Médecine ©️ @lel-media.bsky.social

May 20, 2025 · 4 likes · 1 share View post →
Marcus Hofmann
@M_Hofmann83 · X

Pavanello S, Moretto A, La Vecchia C, Alicandro G. Non-sugar sweeteners and cancer: Toxicological and epidemiological evidence. Regul Toxicol Pharmacol. 2023 Mar;139:105369. doi: 10.1016/j.yrtph.2023.105369. Epub 2023 Mar 3. PMID: 36870410.

Oct 27, 2024 · 1 like · 320 followers View post →
Miguel Ángel Sogorb
@MASogorb · X

No hay evidencias ni en animales ni en humanos de que los edulcorantes artificiales sean cancerígenos Non-sugar sweeteners and cancer: Toxicological and epidemiological evidence https://t.co/SSG7os9UUA

Sep 30, 2023 · 158 followers View post →
Igor Morr
@igormorr · X

Non-sugar sweeteners and cancer- Review of the experimental data on genotoxicity or carcinogenicity of the specific NSS evaluated, and the epidemiological studies:It concluded that there is no evidence of cancer risk associated to NSS consumption. https://t.co/H5yiC02VHZ https://t.co/FhpjztptuK

Sep 20, 2023 · 3,916 followers View post →
ToxicologyELS
@ToxicologyEls · X

Regulatory Toxicology and Pharmacology Review: Non-sugar sweeteners and cancer: Toxicological and epidemiological evidence https://t.co/tDwNoMAQWX https://t.co/kXC0QDDRet

Sep 18, 2023 · 1 like · 1 share · 116 followers View post →
Pathik Joshi
@pathikj80 · X

@coach_ritika Attaching link to a large meta of human studies done on the subject. https://t.co/ImzET1AL0d Having said that, I am not in favour of getting hooked on diet sodas...once in a while seems alright to me.

Jul 2, 2023 · 1 like · 3,350 followers View post →
Abinash Mohapatra
@Abinashisback · X

RT @pussymonious: @catale7a I am not referring to his authority, there is real evidence linked in his tweet. Actual Scientific research wit…

Jun 30, 2023 · 1 share · 371 followers View post →
Eddie
@pussymonious · X

@catale7a I am not referring to his authority, there is real evidence linked in his tweet. Actual Scientific research with tons of references. Nothing GODLY here. Presuming things without evidence is religious thinking, I never do that. https://t.co/4yLqgjHv8n https://t.co/mOpfLsWO5J

Jun 30, 2023 · 1 like · 1 share · 1,792 followers View post →
Dr. B
@ZerKnowsBest · X

“Science doesn’t care about your feelings” https://t.co/SHCrsB1qNI https://t.co/j5BBhTcYf6

Jun 29, 2023 · 368 followers View post →
Boynja
@Brynjakri · X

@atlifannar Fyrir áhugasama: https://t.co/idv82JhhYg

Jun 29, 2023 · 208 followers View post →
Dallas DuPont
@annoyingscream · X

@alec62131119 @Reuters https://t.co/JqdOStIBAu

Jun 29, 2023 · 26 followers View post →
Kiril
@KirilJT · X

@Dmee82 https://t.co/Y9sO1tEV7L

Jun 29, 2023 · 98 followers View post →
Mayank
@SeeMayanks · X

https://t.co/RdpGYWfRt7

Jun 29, 2023 · 135 followers View post →
Survivor of the Norwegian butter crisis 2011
@LillianSoe · X

@hasanthehun There is no evidence showing aspartame causes cancer in humans https://t.co/TG6cNXnsBk

Jun 29, 2023 · 2 likes · 1,806 followers View post →
Ali
@IAliHC · X

@fasi_zaka https://t.co/GbcOowIFwM

Jun 29, 2023 · 398 followers View post →
Ali
@IAliHC · X

@Huk06 From the same article. https://t.co/GbcOowIFwM https://t.co/fn04vMZJxv

Jun 29, 2023 · 398 followers View post →
Aidan Daly
@aidandalytech · X

@washingtonpost There is 0 evidence that aspartame is carcinogenic. Plus, the alternative is sugar... https://t.co/Inhz9e2Mwh

Jun 29, 2023 · 135 followers View post →
Amritanshu Rath(he/him/his)
@amritanshu_rath · X

@SynapseDot Aspartame does not cause cancer folks. https://t.co/knCKTqkKWO

Jun 29, 2023 · 4 likes · 163 followers View post →
Amritanshu Rath(he/him/his)
@amritanshu_rath · X

@DrDhruvchauhan https://t.co/knCKTqkKWO

Jun 29, 2023 · 163 followers View post →
AMITRANJAN GANTAIT
@agantait · X

This topic is so debated and there is hardly any agreement. "Some risks for bladder, pancreas and hematopoietic cancers found in a few studies were not confirmed in other studies". (https://t.co/D5hUy5rUvl) Corporates will definitely take advantage of such situations! https://t.co/3MkH2IXanY

Jun 29, 2023 · 139 followers View post →
sw oo sh
@hsoows__ · X

@902Creed most research actually points to there being no link https://t.co/STwNH9ETW3

Jun 29, 2023 · 107 followers View post →
Michael Manderville, RD
@Manderville_RD · X

@guardian This is not based on evidence https://t.co/BenAajfnV7

Jun 29, 2023 · 18 likes · 1,316 followers View post →
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