Int J Mol Sci February 2023 PMID 36901696

Cholesterol Remnants, Triglyceride-Rich Lipoproteins and Cardiovascular Risk.

Francesco Baratta, Nicholas Cocomello, Mattia Coronati, Domenico Ferro, Daniele Pastori, Francesco Angelico, Maria Del Ben

Mentions

3
Peak: 2 in Apr 2024
across 2 sources since Feb 2023

Extended reach

1,464
potential audience

Total likes

26

Video views

909

Mentions per month

Feb 2023 – Apr 2024

Where it's discussed

  • YouTube2 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

Discussion posts reflect a balanced view, with some highlighting the significance of remnant cholesterol’s role in atherosclerosis, using phrases like 'crucial insight' and 'paradigm shift,' which indicate deep engagement. The tone is analytical and forward-looking, emphasizing the importance of further research and potential implications for cardiovascular risk management.

AgreementModerate agreement

Most discussions acknowledge the importance of the research findings related to residual cardiovascular risk and the role of remnant lipoproteins.

InterestModerate interest

Participants show moderate curiosity, with some expressing interest in how these findings could influence future treatments.

EngagementModerate engagement

Posts often reference specific aspects of the publication, such as the causal role of remnant cholesterol and the potential for new pharmacological approaches.

ImpactModerate impact

The debates suggest a recognition that the research could potentially influence clinical practices and guide further investigations.

Abstract in brief

  • Residual cardiovascular risk remains even after LDL cholesterol lowering treatments, mainly linked to remnants of triglyceride-rich lipoproteins such as remnant cholesterol (RC) which include VLDL and chylomicron remnants.
  • RCs are present in both fasting and nonfasting states and represent the total plasma cholesterol minus HDL and LDL cholesterol, involving cholesterol in various lipoproteins that can promote atherosclerosis by crossing arterial walls and stimulating cell growth.
  • Experimental and clinical evidence indicates that RCs play a significant causal role in cardiovascular disease, but further research is needed to explore drug effects on RC levels and to determine if lowering RCs can reduce cardiovascular events.]

Top posts

Most liked on X and Bluesky
MyJournals
@myjournals · X

IJMS, Vol. 24, Pages 4268: Cholesterol Remnants, Triglyceride-Rich Lipoproteins and Cardiovascular Risk https://t.co/GNcsCVQk5w

Feb 21, 2023 · 555 followers View post →

All mentions

MyJournals
@myjournals · X

IJMS, Vol. 24, Pages 4268: Cholesterol Remnants, Triglyceride-Rich Lipoproteins and Cardiovascular Risk https://t.co/GNcsCVQk5w

Feb 21, 2023 · 555 followers View post →