Functional neurological restoration of amputated peripheral nerve using biohybrid regenerative bioelectronics.

Amy E Rochford, Alejandro Carnicer-Lombarte, Malak Kawan, Amy Jin, Sam Hilton, Vincenzo F Curto, Alexandra L Rutz, Thomas Moreau, Mark R N Kotter, George G Malliaras, Damiano G Barone

March 2023 Sci Adv

Synopsis of Social media discussions

Several posts celebrate the potential of biohybrid neural interfaces, frequently using words like 'exciting,' 'groundbreaking,' and 'game changer' to emphasize their enthusiasm. For instance, one individual expressed exhilaration, referencing an interview related to curing disabilities, highlighting the transformative nature of such technologies. The tone across these discussions conveys a collective anticipation for future developments and applications stemming from the article.

A
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The overwhelming majority of discussions express strong support for the innovative findings of the publication.

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Interest
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Participants in these digital discussions show a high level of curiosity about the applications and implications of the research.

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Engagement
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While many participants engage by sharing content related to the topic, the depth of engagement varies, with some focusing more on supplementary content than the core publication.

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Impact
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Many contributors believe the research could lead to significant advancements in medical technology and disability interventions.

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Twitter

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306

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Abstract Synopsis

  • Researchers have developed a new type of neural interface that uses induced pluripotent stem cell (iPSC)-derived myocytes, which are essential for improving the integration and biocompatibility of devices in the nervous system.
  • The device has shown long-term survival and functional integration with rat forearm nerve bundles after 4 weeks, indicating promising advancements in restoring neurological functions.
  • The introduction of an intermediate cell layer enhances the interface between tissue and electronics, leading to better resolution and electrical recording capabilities, paving the way for future restorative therapies using bioelectronics.