Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions.

Robert C Glastad, Iain G Johnston

March 2023 PLoS Comput Biol

Synopsis of Social media discussions

Discussions highlight that mitochondrial network structures influence mtDNA inheritance patterns during cell division, with posts praising the research for its detailed analysis and potential implications. Words like 'delighted' and mentions of control over inheritance reflect enthusiasm and recognition of importance, though some posts focus on network collaboration rather than the genetic implications.

A
Agreement
 Moderate agreement

Most discussions recognize the significance of mitochondrial network structures in controlling mtDNA inheritance, with some emphasizing its biological importance.

I
Interest
 High level of interest

Participants show high interest, as evidenced by enthusiastic expressions like 'delighted' and focus on the details of mtDNA variability.

E
Engagement
 Moderate level of engagement

Posts actively engage with the article's implications, mentioning potential mechanisms and biological relevance, though some are more brief or reactive.

I
Impact
 Moderate level of impact

While there is recognition of the study's relevance, the discussions mainly focus on basic insights rather than transformative impacts on the field.

Social Mentions

YouTube

1 Videos

Twitter

52 Posts

Metrics

Video Views

50

Total Likes

172

Extended Reach

276,734

Social Features

53

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Mitochondrial Network Structure and mtDNA Variability in Cells

Mitochondrial Network Structure and mtDNA Variability in Cells

This video explores how mitochondrial network structure influences cell-to-cell mtDNA variability generated during cell divisions. The research highlights findings from authors Robert C Glastad and Iain G Johnston, emphasizing the dynamic role of mitochondria.

Social RTCL TV

July 25, 2023

50 views

  • Piero De Dominicis
    @dedo6923 (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 17, 2025

    24

  • Ahmed Ezat
    @AhmedAdelEzat (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 9, 2025

    24

  • Madam Mitochondria
    @Madam_Mito (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 8, 2025

    24

  • iArmandoVBaneado
    @iArmandoVBanned (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    January 28, 2025

    24

  • Ali Nasser
    @BioMedAli (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    January 28, 2025

    24

  • Manoj Mayogi Mishra
    @mayogisense (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    January 27, 2025

    24

  • Dr Richard Palmquist
    @DrRPalmquist (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    August 23, 2024

    24

  • Madam Mitochondria
    @Madam_Mito (Twitter)

    RT @Madam_Mito: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX
    view full post

    August 23, 2024

    6

  • Madam Mitochondria
    @Madam_Mito (Twitter)

    RT @Madam_Mito: @PathfinderEq @alantomusiak mtDNA isn’t as important as network collaboration though. https://t.co/TPn95tDHfM
    view full post

    June 22, 2024

    1

  • FIT_PUMP_
    @fit_pump_ (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    June 4, 2024

    24

  • BillOckham
    @BillOccham0 (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • Lisa Vlad
    @LisaVlad2 (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • Adolfo Reyes
    @Dr_AStemCells (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • Shams Salah Mahdi
    @ShamsPath (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • kNr
    @4constellation (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • P123
    @P1231032850 (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין
    @Alexis_Lomakin (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • Bayar Jaff
    @JaffBayar (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • Hao Yin
    @HaoYin20 (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • John Greene
    @Greene_Thoughts (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • Takuya Norizuki
    @T_Norizuki (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • T-MaX84
    @max_ev_84 (Twitter)

    RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…
    view full post

    May 13, 2024

    24

  • Madam Mitochondria
    @Madam_Mito (Twitter)

    https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions
    view full post

    May 13, 2024

    82

    24

  • Madam Mitochondria
    @Madam_Mito (Twitter)

    @PathfinderEq @alantomusiak mtDNA isn’t as important as network collaboration though. https://t.co/TPn95tDHfM
    view full post

    March 29, 2024

    6

    1

  • Ruben QC
    @RubenQC_Lab (Twitter)

    RT @Madam_Mito: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX
    view full post

    January 1, 2024

    6

  • Madam Mitochondria
    @Madam_Mito (Twitter)

    RT @Madam_Mito: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX
    view full post

    January 1, 2024

    6

  • Eduardo Silva-Pavez
    @EduSilvaPavez (Twitter)

    RT @philosophising4: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1ASh…
    view full post

    April 2, 2023

    6

  • Chih-Yao Chung
    @chihyaochung (Twitter)

    RT @philosophising4: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1ASh…
    view full post

    April 2, 2023

    6

  • Tasleem Arif
    @tashu100 (Twitter)

    RT @philosophising4: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1ASh…
    view full post

    April 2, 2023

    6

  • Madam Mitochondria
    @Madam_Mito (Twitter)

    Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX
    view full post

    April 2, 2023

    20

    6

  • Yiyuan Li (YY)
    @yy_yiyuan_li (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 28, 2023

    13

  • Dan Sloan
    @SloanEvoLab (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 28, 2023

    13

  • fuzzyLife
    @animesh1977 (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Rutter Lab
    @RutterLab (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Nathalie Reuter
    @reuter_nathalie (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Kostas Giannakis
    @kostas21 (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Salva Duran-Nebreda
    @SDuranNebreda (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Jason Chen
    @thyreodon (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Pål R. Njølstad
    @PalRNjolstad (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Joanna Chustecki
    @ChusteckiSci (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Cameron A. Schmidt, PhD
    @CAS_ReproLab (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Michael Jon Palmquist
    @MJPalmquist82 (Twitter)

    RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…
    view full post

    March 27, 2023

    13

  • Iain Johnston
    @mitomaths (Twitter)

    New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can control the inheritance of copy number and heteroplasmy at cell divisions, allowing either faithful inheritance or the generation of useful variability. https://t.co/VsFlSGudku https://t.co/8LCb9gGu9q
    view full post

    March 27, 2023

    35

    13

  • Hector Flores Romero
    @floresromeroh (Twitter)

    RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp
    view full post

    July 1, 2022

    7


  • @Mitominder (Twitter)

    RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp
    view full post

    June 30, 2022

    7

  • Catalina Vasilescu, PhD
    @_CVasilescu (Twitter)

    RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp
    view full post

    June 30, 2022

    7

  • Ryan Cupo
    @Ryan_Cupo (Twitter)

    Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/BX9C9reejg
    view full post

    June 30, 2022

  • Glenn Bantug
    @gbantug2000 (Twitter)

    RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp
    view full post

    June 30, 2022

    7

  • Candice B. Limper, PhD
    @LimperScience (Twitter)

    RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp
    view full post

    June 30, 2022

    7

  • Hansi WEISSENSTEINER
    @whansi (Twitter)

    Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp
    view full post

    June 30, 2022

    25

    7

  • bioRxiv Genetics
    @biorxiv_genetic (Twitter)

    Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/1YhizqsAUq #biorxiv_genetic
    view full post

    June 29, 2022

  • bioRxiv
    @biorxivpreprint (Twitter)

    Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/q5eSUSrUuU #bioRxiv
    view full post

    June 29, 2022

    4

Abstract Synopsis

  • Mitochondria form various structures within cells, such as reticulated networks or fragmented pieces, which influence how mitochondrial DNA (mtDNA) is inherited during cell division.
  • The study uses models to analyze how these mitochondrial network structures affect the variability in inherited mtDNA copy numbers and mutant loads, highlighting situations where simple statistical approaches may fall short.
  • Findings suggest that the organization of mitochondrial networks can either increase or decrease heteroplasmy variance (diversity in mtDNA types), allowing cells to regulate mtDNA inheritance based on different biological priorities.]