PLoS Comput Biol March 2023 PMID 36952562

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions.

Robert C Glastad, Iain G Johnston

Mentions

53
Peak: 13 in Mar 2023
across 2 sources since Jun 2022

Extended reach

276,734
potential audience

Total likes

172

Video views

50

Mentions per month

Jun 2022 – May 2025

Where it's discussed

  • X / Twitter52 posts
  • YouTube1 videos

AI synopsis

What people are saying

Discussions highlight that mitochondrial network structures influence mtDNA inheritance patterns during cell division, with posts praising the research for its detailed analysis and potential implications. Words like 'delighted' and mentions of control over inheritance reflect enthusiasm and recognition of importance, though some posts focus on network collaboration rather than the genetic implications.

AgreementModerate agreement

Most discussions recognize the significance of mitochondrial network structures in controlling mtDNA inheritance, with some emphasizing its biological importance.

InterestHigh interest

Participants show high interest, as evidenced by enthusiastic expressions like 'delighted' and focus on the details of mtDNA variability.

EngagementModerate engagement

Posts actively engage with the article's implications, mentioning potential mechanisms and biological relevance, though some are more brief or reactive.

ImpactModerate impact

While there is recognition of the study's relevance, the discussions mainly focus on basic insights rather than transformative impacts on the field.

Abstract in brief

  • Mitochondria form various structures within cells, such as reticulated networks or fragmented pieces, which influence how mitochondrial DNA (mtDNA) is inherited during cell division.
  • The study uses models to analyze how these mitochondrial network structures affect the variability in inherited mtDNA copy numbers and mutant loads, highlighting situations where simple statistical approaches may fall short.
  • Findings suggest that the organization of mitochondrial networks can either increase or decrease heteroplasmy variance (diversity in mtDNA types), allowing cells to regulate mtDNA inheritance based on different biological priorities.]

Top posts

Most liked on X and Bluesky
Madam Mitochondria
@Madam_Mito · X

https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions

May 13, 2024 · 82 likes · 24 shares · 10,310 followers View post →
Iain Johnston
@mitomaths · X

New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can control the inheritance of copy number and heteroplasmy at cell divisions, allowing either faithful inheritance or the generation of useful variability. https://t.co/VsFlSGudku https://t.co/8LCb9gGu9q

Mar 27, 2023 · 35 likes · 13 shares · 1,392 followers View post →
Hansi WEISSENSTEINER
@whansi · X

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp

Jun 30, 2022 · 25 likes · 7 shares · 551 followers View post →
Madam Mitochondria
@Madam_Mito · X

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX

Apr 2, 2023 · 20 likes · 6 shares · 10,310 followers View post →
Madam Mitochondria
@Madam_Mito · X

@PathfinderEq @alantomusiak mtDNA isn’t as important as network collaboration though. https://t.co/TPn95tDHfM

Mar 29, 2024 · 6 likes · 1 share · 10,310 followers View post →
bioRxiv
@biorxivpreprint · X

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/q5eSUSrUuU #bioRxiv

Jun 29, 2022 · 4 likes · 136,934 followers View post →

All mentions

Piero De Dominicis
@dedo6923 · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 17, 2025 · 24 shares · 12 followers View post →
Ahmed Ezat
@AhmedAdelEzat · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 9, 2025 · 24 shares · 86 followers View post →
Madam Mitochondria
@Madam_Mito · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 8, 2025 · 24 shares · 10,310 followers View post →
iArmandoVBaneado
@iArmandoVBanned · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

Jan 28, 2025 · 24 shares · 68 followers View post →
Ali Nasser
@BioMedAli · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

Jan 28, 2025 · 24 shares · 17 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

Jan 27, 2025 · 24 shares · 572 followers View post →
Dr Richard Palmquist
@DrRPalmquist · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

Aug 23, 2024 · 24 shares · 4,724 followers View post →
Madam Mitochondria
@Madam_Mito · X

RT @Madam_Mito: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX

Aug 23, 2024 · 6 shares · 10,310 followers View post →
Madam Mitochondria
@Madam_Mito · X

RT @Madam_Mito: @PathfinderEq @alantomusiak mtDNA isn’t as important as network collaboration though. https://t.co/TPn95tDHfM

Jun 22, 2024 · 1 share · 10,310 followers View post →
FIT_PUMP_
@fit_pump_ · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

Jun 4, 2024 · 24 shares · 304 followers View post →
BillOckham
@BillOccham0 · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 588 followers View post →
Lisa Vlad
@LisaVlad2 · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 102 followers View post →
Adolfo Reyes
@Dr_AStemCells · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 58 followers View post →
Shams Salah Mahdi
@ShamsPath · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 1,435 followers View post →
kNr
@4constellation · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 635 followers View post →
P123
@P1231032850 · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 3,190 followers View post →
Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין
@Alexis_Lomakin · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 3,649 followers View post →
Bayar Jaff
@JaffBayar · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 607 followers View post →
Hao Yin
@HaoYin20 · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 12,212 followers View post →
John Greene
@Greene_Thoughts · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 1,675 followers View post →
Takuya Norizuki
@T_Norizuki · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 281 followers View post →
T-MaX84
@max_ev_84 · X

RT @Madam_Mito: https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell division…

May 13, 2024 · 24 shares · 1,461 followers View post →
Madam Mitochondria
@Madam_Mito · X

https://t.co/P1AShnKI0p Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions

May 13, 2024 · 82 likes · 24 shares · 10,310 followers View post →
Madam Mitochondria
@Madam_Mito · X

@PathfinderEq @alantomusiak mtDNA isn’t as important as network collaboration though. https://t.co/TPn95tDHfM

Mar 29, 2024 · 6 likes · 1 share · 10,310 followers View post →
Ruben QC
@RubenQC_Lab · X

RT @Madam_Mito: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX

Jan 1, 2024 · 6 shares · 2,551 followers View post →
Madam Mitochondria
@Madam_Mito · X

RT @Madam_Mito: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX

Jan 1, 2024 · 6 shares · 10,310 followers View post →
Eduardo Silva-Pavez
@EduSilvaPavez · X

RT @philosophising4: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1ASh…

Apr 2, 2023 · 6 shares · 134 followers View post →
Chih-Yao Chung
@chihyaochung · X

RT @philosophising4: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1ASh…

Apr 2, 2023 · 6 shares · 488 followers View post →
Tasleem Arif
@tashu100 · X

RT @philosophising4: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1ASh…

Apr 2, 2023 · 6 shares · 87 followers View post →
Madam Mitochondria
@Madam_Mito · X

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/P1AShnLfPX

Apr 2, 2023 · 20 likes · 6 shares · 10,310 followers View post →
Yiyuan Li (YY)
@yy_yiyuan_li · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 28, 2023 · 13 shares · 523 followers View post →
Dan Sloan
@SloanEvoLab · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 28, 2023 · 13 shares · 758 followers View post →
fuzzyLife
@animesh1977 · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 1,738 followers View post →
Rutter Lab
@RutterLab · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 8,735 followers View post →
Nathalie Reuter
@reuter_nathalie · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 1,196 followers View post →
Kostas Giannakis
@kostas21 · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 47 followers View post →
Salva Duran-Nebreda
@SDuranNebreda · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 1,258 followers View post →
Jason Chen
@thyreodon · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 431 followers View post →
Pål R. Njølstad
@PalRNjolstad · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 341 followers View post →
Joanna Chustecki
@ChusteckiSci · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 399 followers View post →
Cameron A. Schmidt, PhD
@CAS_ReproLab · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 1,433 followers View post →
Michael Jon Palmquist
@MJPalmquist82 · X

RT @mitomaths: New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can co…

Mar 27, 2023 · 13 shares · 67 followers View post →
Iain Johnston
@mitomaths · X

New paper 1/2! Delighted that this is now out! https://t.co/lKjq7fI6UO mtDNA placement within mitochondrial networks can control the inheritance of copy number and heteroplasmy at cell divisions, allowing either faithful inheritance or the generation of useful variability. https://t.co/VsFlSGudku https://t.co/8LCb9gGu9q

Mar 27, 2023 · 35 likes · 13 shares · 1,392 followers View post →
Hector Flores Romero
@floresromeroh · X

RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp

Jul 1, 2022 · 7 shares · 308 followers View post →
Mitominder
@Mitominder · X

RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp

Jun 30, 2022 · 7 shares · 2,258 followers View post →
Catalina Vasilescu, PhD
@_CVasilescu · X

RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp

Jun 30, 2022 · 7 shares · 1,048 followers View post →
Ryan Cupo
@Ryan_Cupo · X

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/BX9C9reejg

Jun 30, 2022 · 570 followers View post →
Glenn Bantug
@gbantug2000 · X

RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp

Jun 30, 2022 · 7 shares · 124 followers View post →
Candice B. Limper, PhD
@LimperScience · X

RT @whansi: Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp

Jun 30, 2022 · 7 shares · 3,260 followers View post →
Hansi WEISSENSTEINER
@whansi · X

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/cSeHjPwFsp

Jun 30, 2022 · 25 likes · 7 shares · 551 followers View post →
bioRxiv Genetics
@biorxiv_genetic · X

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/1YhizqsAUq #biorxiv_genetic

Jun 29, 2022 · 4,690 followers View post →
bioRxiv
@biorxivpreprint · X

Mitochondrial network structure controls cell-to-cell mtDNA variability generated by cell divisions https://t.co/q5eSUSrUuU #bioRxiv

Jun 29, 2022 · 4 likes · 136,934 followers View post →