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This discussion consistently revolves around viewing aging as a software problem, with posts referencing the article's core idea of 'reprogramming' aging, such as mentions of epigenetic software updates and developmental programs. The tone emphasizes excitement about potential breakthroughs, with phrases like 'game changer' and 'exciting' indicating strong interest and perceived significance.
Most posts support the idea that aging functions like a software issue, reflecting broad agreement with the publication's thesis.
The discussion showcases high curiosity about aging as a programmable process, with many posts highlighting the potential for reprogramming and technological intervention.
Posts delve into specific concepts like epigenetic reprogramming and evolutionary theories, indicating active participation and deeper understanding.
The collective interest in future applications, such as reprogramming aging, suggests the topic could influence ongoing research and societal views on aging.
I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a programmatic process that results not from the corruption of the software but rather from software programs that run-on. https://t.co/BUgO5slc8P https://t.co/772rOoyvVA
Obrigado pela paciência, Lucas! Para complementar mais a discussão recomendo o ep 379 do @naruhodopodcast - Como nós nos tornamos nós? https://t.co/n3X1VNwk7z https://t.co/Xx5Ti5ZoPP
Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why we age remains a hotly contested topic. Most mechanistic explanations of ageing posit that ageing is caused by the accumulation of one or more forms of https://t.co/3WcdKL6O5A
Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming our outdated software away from diseases & aging, which he calls "bridge 2". This is something he talked about for many years. https://t.co/8HvIjjCqWX
The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Included is my talk on ageing as a software design flaw as an attempt to explain the biodiversity of ageing. https://t.co/lsJr6tQrhd https://t.co/yBUqrye1wG
The recent review published by @jpsenescence in @BioMedCentral will be helpful for those who are struggling to determine where to position evolutionary theories of ageing, cancer and Yamanaka factors while trying to understand the enigma of ageing. https://t.co/RyNDkLzbut
Why do we age? This video explores various aging theories, including DNA damage, free radicals, epigenetics, and more, emphasizing recent insights into aging as a biological software flaw and changes in cellular…
This episode explores the development of early humans' hafted hunting tools around 500,000 years ago and discusses whether artificial intelligence can possess the ability to understand mental states, traditionally…
This video discusses an article proposing that aging results from software bugs in DNA control of cell development, comparing this to other theories and emphasizing the role of epigenetic changes in aging.
RT @jpsenescence: @MicahZoltu @MitsuMaHealth @davidasinclair I agree to some degree. On the other hand, we know from cloning, reproduction…
@MicahZoltu @MitsuMaHealth @davidasinclair I agree to some degree. On the other hand, we know from cloning, reproduction and reprogramming that it's possible to reset the epigenome. Figure below from my paper: https://t.co/BUgO5slc8P https://t.co/GUKL9lU0bi
@cutleraging @davidasinclair Good question, I think damage contributes to some specific diseases (namely, cancer), but most aging phenotypes can be programmatic. Please see: https://t.co/BUgO5slc8P
In my humble opinion, this paper by @drmichaellevin, @LPiolopez & @BeneHartl is one of the most consequential of recent years. @jpsenescence: I think it doesn’t negate your “ageing as a software design flaw” idea but rather reframes it. It’s not that the software was badly https://t.co/b6NRpzQ1iy
RT @jpsenescence: @atse_zola @davidasinclair https://t.co/BUgO5slc8P
@atse_zola @davidasinclair https://t.co/BUgO5slc8P
RT @jpsenescence: @AlexanderMWolf7 Given that rapa slows growth, I think it fits antagonistic pleiotropy, see: https://t.co/BUgO5slc8P
@AlexanderMWolf7 Given that rapa slows growth, I think it fits antagonistic pleiotropy, see: https://t.co/BUgO5slc8P
@davidjglassMD Agree
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
https://t.co/q1tvkDdlca
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
RT @jpsenescence: I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a pro…
I agree with David in seeing ageing as a software problem, namely a software design flaw. However, I see ageing as a programmatic process that results not from the corruption of the software but rather from software programs that run-on. https://t.co/BUgO5slc8P https://t.co/772rOoyvVA
@CharlesMBrenner I think aging processes begin during development, but until around age 20-30 they are only mildly detrimental - mortality only begins to increase exponentially around age 30. https://t.co/BUgO5slJYn
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @organelletx:
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
RT @vietly_7: Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why w…
Ageing as a software design flaw. By João Pedro de Magalhães @jpsenescence Ageing is inherent to all human beings, yet why we age remains a hotly contested topic. Most mechanistic explanations of ageing posit that ageing is caused by the accumulation of one or more forms of https://t.co/3WcdKL6O5A
@ArtirKel Absolutely, developmental programs that run-on later in life have a major impact on ageing. https://t.co/BUgO5slJYn
Ageing as a software design flaw https://t.co/S1zpqOIfke
@epsilonklm @jpsenescence thinks that aging is the continuation of development, see https://t.co/67aK6yQJhu
@ajkirby01 Yes, I do, please see: https://t.co/BUgO5slc8P
@vtchakarova Not at all, human aging didn’t evolve for a purpose, rather it is the result of evolutionary neglect because the force of natural selection declines after reproduction. I call aging a software design flaw, please see: https://t.co/BUgO5slc8P
RT @jpsenescence: A thread on ageing as a software design flaw
@MikhailBatin In a way, yes, please see: https://t.co/BUgO5slJYn
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
https://t.co/n0wSgFnwCA
@RuxandraTeslo Agree, and plz check out our software design flaw hypothesis that predicts that differences in longevity between species are due to differences in the pace of development: https://t.co/BUgO5slc8P
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
@LidskyPeter For one I'm not convinced senescent cells are a driver of aging, see my software design flaw paper: https://t.co/BUgO5slc8P
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
RT @jpsenescence: The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Includ…
The talks from the recent Expanding evolutionary theories of ageing colloquium in Paris are now available online. Included is my talk on ageing as a software design flaw as an attempt to explain the biodiversity of ageing. https://t.co/lsJr6tQrhd https://t.co/yBUqrye1wG
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
Ageing as a software design flaw | Genome Biology | Full Text https://t.co/p7iBuMGqDe
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: Overall, ageing is an information problem. I suggest that to understand ageing we need to decode our genetic software an…
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
https://t.co/HWdg1oQAsF
RT @ElUltimoSapiens: @ElUltimoSapiens: les recomiendo esta reflexión del Dr. Magalhaes sobre el envejecimiento. https://t.co/d73QZkFOvX
@ElUltimoSapiens: les recomiendo esta reflexión del Dr. Magalhaes sobre el envejecimiento. https://t.co/d73QZkFOvX
@PeterDiamandis Yes, aging is a systems problem we can fix by tweaking the software! https://t.co/aOZQzIVuEh
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
@95thoughts @RuxandraTeslo @browserdotsys I think title is attention grab and ignore it,this is a developmentalist take, but there are are explanations for ageing clocks,regularity instead of randomness etc. that don't rely of ageing as a programmed adaptation, it's still consistent with sideffect https://t.co/fp8nSSlwtk
RT @altayals: Obrigado pela paciência, Lucas! Para complementar mais a discussão recomendo o ep 379 do @naruhodopodcast - Como nós nos torn…
RT @altayals: Obrigado pela paciência, Lucas! Para complementar mais a discussão recomendo o ep 379 do @naruhodopodcast - Como nós nos torn…
Obrigado pela paciência, Lucas! Para complementar mais a discussão recomendo o ep 379 do @naruhodopodcast - Como nós nos tornamos nós? https://t.co/n3X1VNwk7z https://t.co/Xx5Ti5ZoPP
RT @jpsenescence: @Aria_Babu I would argue that aging is a program, though not a program that was intentionally designed to harm us. http…
RT @jpsenescence: @Aria_Babu I would argue that aging is a program, though not a program that was intentionally designed to harm us. http…
RT @jpsenescence: @Aria_Babu I would argue that aging is a program, though not a program that was intentionally designed to harm us. http…
@Aria_Babu I would argue that aging is a program, though not a program that was intentionally designed to harm us. https://t.co/BUgO5slc8P
Ageing as a software design flaw | Genome Biology | Full Text https://t.co/aFzq6MTqdm
Highlight: Paper by @jpsenescence published Mar 2023, titled "Ageing as a software design flaw"
RT @jpsenescence: A thread on ageing as a software design flaw
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
Será que um dia conseguiremos dar um novo "boot" no sistema? Researchers suggest that human aging is the end-product of our developmental program https://t.co/hbmZ7OgTBJ https://t.co/Uu3wcUtLqo https://t.co/4eYSRWjBmt
RT @luisamfigueired: Exciting to learn about ageing as a software design flaw, by Joao Pedro de Magalhaes. @jpsenescence @IMMolecular h…
Exciting to learn about ageing as a software design flaw, by Joao Pedro de Magalhaes. @jpsenescence @IMMolecular https://t.co/7GdVPS2Y0Z
RT @ntzplural: Neste vídeo, Nicolás comenta sobre um artigo publicado há algumas semanas pelo cientista português @jpsenescence, que propõe…
Link para o artigo de João Pedro de Magalhães: https://t.co/b3E5M3398I Link do livro de Harold Katcher "A ilusão do conhecimento": https://t.co/W1J1vdos5I
Neste vídeo, Nicolás comenta sobre um artigo publicado há algumas semanas pelo cientista português @jpsenescence, que propõe que o envelhecimento é causado por falhas no software do desenvolvimento. https://t.co/oMcqSToAPW #envelhecimento #rejuvenescimento #ciência
RT @jpsenescence: A thread on ageing as a software design flaw
RT @BioDecoded: Ageing as a software design flaw | Genome Biology https://t.co/a8VbpBPu6t #ageing https://t.co/oihZWVJUma
Ageing as a software design flaw | Genome Biology https://t.co/a8VbpBPu6t #ageing https://t.co/oihZWVJUma
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
RT @zahidasultanova: The recent review published by @jpsenescence in @BioMedCentral will be helpful for those who are struggling to determi…
Ageing as a software design flaw | Genome Biology | Full Text https://t.co/p7iBuMGqDe
RT @zahidasultanova: The recent review published by @jpsenescence in @BioMedCentral will be helpful for those who are struggling to determi…
RT @zahidasultanova: The recent review published by @jpsenescence in @BioMedCentral will be helpful for those who are struggling to determi…
RT @zahidasultanova: The recent review published by @jpsenescence in @BioMedCentral will be helpful for those who are struggling to determi…
The recent review published by @jpsenescence in @BioMedCentral will be helpful for those who are struggling to determine where to position evolutionary theories of ageing, cancer and Yamanaka factors while trying to understand the enigma of ageing. https://t.co/RyNDkLzbut
RT @jpsenescence: A thread on ageing as a software design flaw
A thread on aging as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
Ageing as a software design flaw https://t.co/hSDIlJS78E
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
RT @davidasinclair: New article by @jpsenescence presenting the case for aging being a software problem. Couldn’t agree more #informationth…
Ageing as a software design flaw https://t.co/NFWVvwsujy
Ageing as a software design flaw | Genome Biology | Full Text https://t.co/G54KTGOn3t
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @jpsenescence: A thread on ageing as a software design flaw
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
RT @Sotnedal: Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming…
Time to slow down this flawed software I have been running for the past 30+ years. Fascinating read. Ageing as a software design flaw - Genome Biology https://t.co/N3MKyi6xPs https://t.co/95uvCW2Sar
Ageing as a software design flaw - Genome Biology Ray Kurzweil was way ahead of his time. He often talks about reprogramming our outdated software away from diseases & aging, which he calls "bridge 2". This is something he talked about for many years. https://t.co/8HvIjjCqWX
Ageing as a software design flaw | Genome Biology | Full Text https://t.co/XxovAoF4Mx
RT @jpsenescence: A thread on ageing as a software design flaw
Ageing as a software design flaw. So exciting ! https://t.co/X3LqAJ47xI
Ageing as a software design flaw / bio hacking / neuroscience / epigenetic / fasting / mineral engineering https://t.co/zZTm3kUds0
RT @moorejh: Ageing as a software design flaw https://t.co/LNhE86gcKw #aging #genomics
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
Ageing as a software design flaw - https://t.co/4SUYtGdzOJ #ScholarAlerts
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
RT @jpsenescence: A thread on ageing as a software design flaw
Why do we age? That is the question in "Ageing as a software design flaw." Genome Biol 24, 51 (2023). https://t.co/21FeBMJo1D @isaperarnau @jpsenescence @brunovellas @RestoreInstitut @InfinityTLS @I2mcT
Ageing as a software design flaw https://t.co/Ayfw48JgcR https://t.co/RUs6cp80Zk
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