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Nat Commun April 2023 PMID 37012288

An integrase toolbox to record gene-expression during plant development.

Sarah Guiziou, Cassandra J Maranas, Jonah C Chu, Jennifer L Nemhauser

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Mentions

30
Peak: 16 in Apr 2023
across 3 sources since Sep 2022

Extended reach

227,991
potential audience

Total likes

73

Video views

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Mentions per month

Sep 2022 – Jul 2023

Where it's discussed

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AI synopsis

What people are saying

The discussions around the publication tend to highlight its significance and novelty, with some posts emphasizing congratulations and mentions of the research team's achievements. The tone is supportive and informative, using straightforward language that reflects appreciation and acknowledgment of the potential applications, but does not delve into technical details or critique, indicating a moderate overall interest and perceived impact.

AgreementModerate agreement

Most posts express positive recognition or support for the publication, as shown by phrases like 'New from...' and congratulations to the authors, indicating general approval. There is little evidence of disagreement or skepticism.

InterestModerate interest

The discussions reflect moderate curiosity, with mentions of the key components like the 'integrase toolbox' and notes about its relevance for plant development, suggesting they find the work noteworthy but not overwhelmingly exciting.

EngagementModerate engagement

Participants reference specific aspects of the research, such as gene recording and DNA recombination, and discuss implications, showing a basic level of engagement without deep technical debate or critique.

ImpactModerate impact

The overall tone hints at recognition of the work's importance, especially since some posts highlight awards and support from the scientific community, suggesting perceived significance without dramatic claims.

Abstract in brief

  • This article discusses the development of an integrase toolbox designed to track gene expression during plant development by using special enzymes called serine integrases to permanently record gene activity through DNA recombination, which is visualized by changes in fluorescent reporters.
  • The system can be combined with specific promoters active during processes like lateral root initiation to amplify signals and mark the descendants of cells involved, helping scientists understand the sequence of gene activation.
  • Additionally, the toolbox includes methods to fine-tune the switching behavior of the integrases, making the system more robust and adaptable across different promoters and plant generations, enabling the creation of circuits that decode gene expression patterns during organ formation.
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Top posts

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Tatsuya Nobori
@nobolly · X

An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 8, 2023 · 36 likes · 9 shares · 8,215 followers View post →
CRAG
@cragenomica · X

We want to congratulate @sarah_guiziou from @WU for winning the @agrisera prize

Sep 21, 2022 · 11 likes · 2 shares · 5,308 followers View post →
bioRxiv Synthetic Biology
@bioRxiv_synbio · X

An integrase toolbox to record gene-expression during plant development. https://t.co/C9yM5NNm7n #biorxiv_synbio

Sep 17, 2022 · 9 likes · 1 share · 1,987 followers View post →
IBMCP - Instituto de Biología Molecular y Celular
@IBMCP · X

DON'T FORGET IT!

Jun 23, 2023 · 5 likes · 1 share · 7,221 followers View post →
Carolina Grandellis
@cgrandellis · X

An integrase toolbox to record gene-expression during plant development | Nature Communications https://t.co/wWpNeWtFbF

Apr 9, 2023 · 5 likes · 2 shares · 1,053 followers View post →
Twist Bioscience
@TwistBioscience · X

New from @sarah_guiziou and team in @NatureComms: An integrase toolbox to record gene-expression during plant development. Thank you for choosing Twist to support your work!

Apr 12, 2023 · 4 likes · 1 share · 25,298 followers View post →

All mentions

Earlham Institute
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RT @IBMCP: DON'T FORGET IT!

Jun 23, 2023 · 1 share · 14,363 followers View post →
IBMCP - Instituto de Biología Molecular y Celular
@IBMCP · X

DON'T FORGET IT!

Jun 23, 2023 · 5 likes · 1 share · 7,221 followers View post →
IBMCP - Instituto de Biología Molecular y Celular
@IBMCP · X

RT @IBMCP: DON'T FORGET IT!

Jun 22, 2023 · 1 share · 7,221 followers View post →
IBMCP - Instituto de Biología Molecular y Celular
@IBMCP · X

DON'T FORGET IT!

Jun 22, 2023 · 1 like · 1 share · 7,221 followers View post →
Phage Literature
@phagebot · X

An integrase toolbox to record gene-expression during plant development https://t.co/mK7eJ8rHCZ https://t.co/JFYFeeNJLd

Apr 15, 2023 · 795 followers View post →
priya joseph
@ayirpelle · X

RT @TwistBioscience: New from @sarah_guiziou and team in @NatureComms: An integrase toolbox to record gene-expression during plant developm…

Apr 12, 2023 · 1 share · 4,887 followers View post →
Twist Bioscience
@TwistBioscience · X

New from @sarah_guiziou and team in @NatureComms: An integrase toolbox to record gene-expression during plant development. Thank you for choosing Twist to support your work!

Apr 12, 2023 · 4 likes · 1 share · 25,298 followers View post →
Charly Emmanuel Mam
@CharlyEmmanuel8 · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 10, 2023 · 9 shares · 52 followers View post →
Mark McMullan @mcmullan0.bsky.social
@mcmullan0 · X

RT @cgrandellis: An integrase toolbox to record gene-expression during plant development | Nature Communications https://t.co/wWpNeWtFbF

Apr 9, 2023 · 2 shares · 543 followers View post →
Katherine Rivera-Zuluaga
@Kathe040 · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 9, 2023 · 9 shares · 432 followers View post →
Md Shabab Mehebub
@MehebubShabab · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 9, 2023 · 9 shares · 103 followers View post →
Martin Mayta
@MartinMayta2 · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 9, 2023 · 9 shares · 218 followers View post →
Maria Voloshina
@voloshima · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 9, 2023 · 9 shares · 87 followers View post →
Jangceae X BAE173 X Anime
@Kunkun44489592 · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 9, 2023 · 9 shares · 189 followers View post →
Neil Hall
@neilhall_uk · X

RT @cgrandellis: An integrase toolbox to record gene-expression during plant development | Nature Communications https://t.co/wWpNeWtFbF

Apr 9, 2023 · 2 shares · 3,769 followers View post →
Carolina Grandellis
@cgrandellis · X

An integrase toolbox to record gene-expression during plant development | Nature Communications https://t.co/wWpNeWtFbF

Apr 9, 2023 · 5 likes · 2 shares · 1,053 followers View post →
Andy Garcia
@AndyGPhD · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 8, 2023 · 9 shares · 256 followers View post →
Eunkyoo Oh
@Eunkyoo_Oh · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 8, 2023 · 9 shares · 173 followers View post →
Tengfei Liu
@hzau6 · X

RT @nobolly: An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 8, 2023 · 9 shares · 98 followers View post →
Tatsuya Nobori
@nobolly · X

An integrase toolbox to record gene-expression during plant development　https://t.co/COwC9kLFdz

Apr 8, 2023 · 36 likes · 9 shares · 8,215 followers View post →
Agrisera
@agrisera · X

RT @CRAGENOMICA: We want to congratulate @sarah_guiziou from @WU for winning the @agrisera prize

Sep 23, 2022 · 2 shares · 658 followers View post →
Sarah Guiziou
@sarah_guiziou · X

RT @CRAGENOMICA: We want to congratulate @sarah_guiziou from @WU for winning the @agrisera prize

Sep 21, 2022 · 2 shares · 579 followers View post →
CRAG
@cragenomica · X

We want to congratulate @sarah_guiziou from @WU for winning the @agrisera prize

Sep 21, 2022 · 11 likes · 2 shares · 5,308 followers View post →
Tengfei Liu
@hzau6 · X

RT @bioRxiv_synbio: An integrase toolbox to record gene-expression during plant development. https://t.co/C9yM5NNm7n #biorxiv_synbio

Sep 17, 2022 · 1 share · 98 followers View post →
bioRxiv Synthetic Biology
@bioRxiv_synbio · X

An integrase toolbox to record gene-expression during plant development. https://t.co/C9yM5NNm7n #biorxiv_synbio

Sep 17, 2022 · 9 likes · 1 share · 1,987 followers View post →
bioRxiv
@biorxivpreprint · X

An integrase toolbox to record gene-expression during plant development. https://t.co/JbjqR816fY #bioRxiv

Sep 17, 2022 · 2 likes · 136,934 followers View post →