New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https://t.co/GtWOuqNODH #pharmacology
Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis.
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Apr 2023 – Jun 2024Where it's discussed
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X / Twitter6 posts
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YouTube2 videos
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What people are saying
The discussions primarily highlight the key findings that licorice extract inhibits the cGAS-STING pathway, with phrases like 'new research' and 'protects against NASH' indicating curiosity and recognition of therapeutic promise. The tone is neutral to mildly optimistic, focusing on the new scientific insight rather than in-depth analysis or critique.
Most discussions acknowledge the study's findings that licorice extract can inhibit the cGAS-STING pathway and potentially treat NASH, showing moderate support.
Participants display a general curiosity about the research, mainly emphasizing the novelty of the findings without deep exploration.
Comments show some engagement through mentions of the pathway and potential therapeutic effects, but lack detailed analysis or critique.
The discussions recognize the potential importance of the study but do not demonstrate widespread anticipation of immediate clinical change.
Abstract in brief
- Inflammation and fibrosis are key symptoms of non-alcoholic steatohepatitis (NASH), a common chronic liver disease, and the cGAS-STING signaling pathway is involved in its progression.
- This study examined the effects of licorice extract on the cGAS-STING pathway using bone marrow-derived macrophages and an MCD diet-induced NASH mouse model, showing that licorice can inhibit pathway activation and reduce liver inflammation and fibrosis.
- Licorice extract may serve as a potential therapeutic option for NASH, demonstrating similar effects whether used alone or in combination with the STING inhibitor C-176.
Top posts
Most liked on X and BlueskyLicorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https://t.co/XVsnUjA7Pm https://t.co/LaMDtVSkDA
RT @FrontPharmacol: New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https…
RT @FrontPharmacol: New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https…
RT @FrontPharmacol: New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https…
RT @FrontPharmacol: New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https…
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RT @FrontPharmacol: New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https…
RT @FrontPharmacol: New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https…
RT @FrontPharmacol: New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https…
Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https://t.co/XVsnUjA7Pm https://t.co/LaMDtVSkDA
RT @FrontPharmacol: New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https…
New Research: Licorice extract inhibits the cGAS-STING pathway and protects against non-alcoholic steatohepatitis https://t.co/GtWOuqNODH #pharmacology