PLoS Biol April 2023 PMID 37093850

Biotechnology: Overcoming biological barriers to nucleic acid delivery using lipid nanoparticles.

Alex G Hamilton, Kelsey L Swingle, Michael J Mitchell

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Mentions

18
Peak: 15 in Apr 2023
across 3 sources since Apr 2023

Extended reach

325,053
potential audience

Total likes

61

Video views

17

Mentions per month

Apr 2023 – Oct 2023

Where it's discussed

  • X / Twitter15 posts
  • News2 articles
  • YouTube1 videos

AI synopsis

What people are saying

This collection exemplifies high interest and engagement through references to the development and clinical use of lipid nanoparticles, with phrases like 'engineered to overcome biological barriers' and 'potential for gene therapy,' illustrating enthusiasm and recognition of their transformative role in biotech. The tone and word choices emphasize advancements and future implications, reinforcing the perceived high impact of this research area.

AgreementStrong agreement

All discussions emphasize the importance and success of lipid nanoparticles in overcoming biological barriers for nucleic acid delivery, indicating strong consensus on the article's positive outlook.

InterestHigh interest

Participants show high interest, as reflected in detailed mentions of applications like vaccines and gene therapies, and recognition of technological progress over 20 years.

EngagementHigh engagement

Many discussions delve into specifics, citing examples of advancements, clinical applications, and future potential, demonstrating deep engagement.

ImpactHigh impact

The collective tone suggests that these developments are viewed as game-changing, with mentions of applications in therapies and vaccines highlighting significant scientific and medical impact.

Abstract in brief

  • Biotechnology aims to improve the delivery of therapeutic nucleic acids by overcoming biological barriers through advanced tools like lipid nanoparticles.
  • Over the last 20 years, researchers have developed ionizable lipid nanoparticles, which can effectively carry nucleic acids into cells.
  • These innovations have led to successful clinical applications, demonstrating the potential of lipid nanoparticles in gene therapy and related treatments.]

Top posts

Most liked on X and Bluesky
PLOS Biology
@PLOSBiology · X

Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic acid delivery. In this Perspective, @mjmitchell_lab looks at their development for use in vaccines and therapies #PLOSBiology #biotech https://t.co/7gNOd0Aw7H https://t.co/VVqi2GK6ds

Apr 25, 2023 · 33 likes · 10 shares · 103,145 followers View post →
PLOS Biology
@PLOSBiology · X

Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic acid delivery. In this Perspective, @mjmitchell_lab looks at their development for use in vaccines and therapies #PLOSBiology #biotech https://t.co/7gNOd0B3Xf https://t.co/x8owVjHco6

Apr 25, 2023 · 17 likes · 5 shares · 103,145 followers View post →
PLOS Biology
@PLOSBiology · X

Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic acid delivery. In this Perspective, @mjmitchell_lab looks at their development for use in vaccines and therapies #PLOSBiology #biotech https://t.co/7gNOd0B3Xf https://t.co/cEfl5nMZU9

Apr 25, 2023 · 7 likes · 3 shares · 103,145 followers View post →
Pluchino lab - Regenerative Neuroimmunology
@Pluchinolab · X

Biotechnology: Overcoming biological barriers to nucleic acid delivery using lipid nanoparticles | PLOS Biology https://t.co/Tkh0qBNXa5

Apr 26, 2023 · 4 likes · 2 shares · 4,742 followers View post →
LIPID MAPS
@lipidmaps · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 10 shares · 3,219 followers View post →
Matt Watson
@BioAndBaseball · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 10 shares · 2,985 followers View post →

All mentions

EARA_IE
@EARA_IE · X

RT @Pluchinolab: Biotechnology: Overcoming biological barriers to nucleic acid delivery using lipid nanoparticles | PLOS Biology https://t.…

Apr 26, 2023 · 2 shares · 383 followers View post →
Pluchino lab - Regenerative Neuroimmunology
@Pluchinolab · X

Biotechnology: Overcoming biological barriers to nucleic acid delivery using lipid nanoparticles | PLOS Biology https://t.co/Tkh0qBNXa5

Apr 26, 2023 · 4 likes · 2 shares · 4,742 followers View post →
Ivan Alfaro
@alfobioq · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 5 shares · 821 followers View post →
Jose Hernandez
@Pharma_Mty · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 5 shares · 194 followers View post →
MCLovin
@Valmardon99 · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 3 shares · 666 followers View post →
Wei Roc Song
@WeiRocSong · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 10 shares · 97 followers View post →
PLOS Biology
@PLOSBiology · X

Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic acid delivery. In this Perspective, @mjmitchell_lab looks at their development for use in vaccines and therapies #PLOSBiology #biotech https://t.co/7gNOd0B3Xf https://t.co/cEfl5nMZU9

Apr 25, 2023 · 7 likes · 3 shares · 103,145 followers View post →
MCLovin
@Valmardon99 · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 5 shares · 666 followers View post →
MCLovin
@Valmardon99 · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 10 shares · 666 followers View post →
PLOS Biology
@PLOSBiology · X

Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic acid delivery. In this Perspective, @mjmitchell_lab looks at their development for use in vaccines and therapies #PLOSBiology #biotech https://t.co/7gNOd0B3Xf https://t.co/x8owVjHco6

Apr 25, 2023 · 17 likes · 5 shares · 103,145 followers View post →
Kobbie Reinhard
@Reinhard_kay · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 10 shares · 814 followers View post →
Matt Watson
@BioAndBaseball · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 10 shares · 2,985 followers View post →
LIPID MAPS
@lipidmaps · X

RT @PLOSBiology: Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic aci…

Apr 25, 2023 · 10 shares · 3,219 followers View post →
PLOS Biology
@PLOSBiology · X

Over the past 20 years, lipid-based #nanoparticles have been engineered to overcome the biological barriers to nucleic acid delivery. In this Perspective, @mjmitchell_lab looks at their development for use in vaccines and therapies #PLOSBiology #biotech https://t.co/7gNOd0Aw7H https://t.co/VVqi2GK6ds

Apr 25, 2023 · 33 likes · 10 shares · 103,145 followers View post →
New England BioGroup
@nebiogroup · X

Biotechnology: Overcoming biological barriers to nucleic acid delivery using lipid nanoparticles https://t.co/Qko7Jl3VVV

Apr 24, 2023 · 169 followers View post →