Overall, discussions acknowledge that the 2-year trial found no BMD improvement with creatine during exercise in postmenopausal women, but noted favorable bone geometry changes and lean-mass effects. Debates focus on interpreting geometry versus density, emphasizing safety and the need for larger studies, with a mix of educational framing and cautious interpretation. Examples include mentions like 'no change in hip bone density', 'safety profile is excellent', 'geometry isn't bone density', and calls for putting outcomes in context.
AgreementModerate agreement
Most discussions reproduce the study's main findings (no BMD improvement) and acknowledge safety and some bone-geometry benefits, without大量 contradicting the results. A minority label the result as a 'miss' or call for bigger studies, but overall sentimen
InterestModerate interest
There is curiosity around safety, bone geometry, and the distinction between density and geometry, with several posts offering context or educational framing rather than purely sensational reactions.
EngagementModerate engagement
Discussions go beyond surface summaries, mentioning context, dosing subtleties, and cautions such as 'educational, not medical advice' and 'geometry vs density' debates, though many entries are brief or reposts.
ImpactModerate impact
The discussion conveys moderate impact: safety is emphasized and the nuanced interpretation (geometry changes without density gains) could influence future research or clinical interpretation, but practical guidance remains restrained.
Abstract in brief
Two-year randomized trial in 237 postmenopausal women (mean age ~59) compared creatine monohydrate (0.14 g/kg/day) to placebo during resistance training (3 days/wk) and walking (6 days/wk) to assess bone health.
Creatine did not improve bone mineral density at the femoral neck, total hip, or lumbar spine versus placebo, but it helped maintain proximal femur bone geometry (section modulus) and reduced buckling ratio, indicating better bending resistance.
Among completers, creatine increased lean mass and shortened 80 m walking time, with no additional strength gains beyond training; overall, no BMD benefit but some favorable changes in bone geometry and body composition.
2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mineral density but did enhance other markers associated w/ hip fracture risk.
Minimal adverse events, including kidney & liver health.
https://t.co/eObsjVgVNG
May 8, 2023 · 218 likes · 31 shares · 95,219 followersView post →
DF
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X
Just more evidence that daily creatine supplementation (even at high dosages for long periods of time) cause NO greater adverse effects (markers of kidney and liver function) compared to placebo
#creatine
https://t.co/cecBPMT67P
The SAFETY profile of creatine supplementation is EXCELLENT.
~ 10 grams of creatine every day for 2 years resulted in NO greater prevalence of adverse events vs placebo in postmenopausal women
#creatine #safe #health
https://t.co/cecBPMSyih
Jun 5, 2023 · 61 likes · 21 shares · 6,729 followersView post →
May 10, 2023 · 35 likes · 13 shares · 6,729 followersView post →
ND
Nick Tiller, Ph.D.
@NBTiller · X
More evidence of creatine's benefits. A two-year randomized trial shows creatine supplementation improved bone strength (section modulus and buckling ratio) in postmenopausal women. #creatine #nutrition #strength #bone #health @MSSEonline
May 12, 2023 · 22 likes · 4 shares · 10,644 followersView post →
DP
Daniel Berglind, PhD
@DanielBerglind · X
RCT: 2 years of creatine supplementation
May 11, 2023 · 21 likes · 4 shares · 7,851 followersView post →
Two-year randomized trial in 237 postmenopausal women compared creatine monohydrate (0.14 g/kg/day) to placebo during resistance training and walking. Creatine did not boost bone mineral density at key sites but helped…
Explores the limits of creatine by comparing it with stem cells in aging and regenerative medicine, highlighting energy metabolism, cellular repair, and how these relate to the hallmarks of aging.
Did you know creatine offers numerous benefits for athletes? Despite skepticism from some in the field, research highlights its positive effects on brain health, sleep, type 2 diabetes, and bone health. Discover more…
In this video, I present the five scientifically supported supplements for women over 40. Based on systematic reviews and clinical trials, this content is designed for those seeking to enhance health, energy, and…
Creatine for bone after menopause? The main result was a miss.
A 2-year trial in 237 postmenopausal women found no change in hip bone density. Creatine did improve walking time and some measures of hip structure, which need bigger studies to confirm.
https://t.co/L1LetKPBPV
1/2 Creatine + training: who was studied? Aging is not a diagnosis. Cards 1-4 cover the context and trial design.
Prof. Scott Forbes / Creatine For Health
https://t.co/v6TwhvpDwk
Educational, not medical advice.
#Creatine https://t.co/jkNd1N4FwA
2/2 Geometry isn't density. Keep bone outcomes and dosing-subgroup limits in context. Cards 5-7 include a checklist.
Prof. Scott Forbes / Creatine For Health
https://t.co/v6TwhvpDwk
Educational, not medical advice.
#Creatine https://t.co/9qfNc7jjAI
Keep the outcome in context: selected bone geometry changed; BMD did not.
Trial: https://t.co/8cAK655SjU
Prof. Scott Forbes / Creatine For Health: https://t.co/v6TwhvpDwk
Educational, not medical advice.
#Creatine https://t.co/xigqynFOUA
Keep training in the picture. The talk notes limited data in diagnosed sarcopenia.
Prof. Scott Forbes / Creatine For Health
https://t.co/v6TwhvpDwk
Educational, not medical advice.
#Creatine #HealthyAging https://t.co/62RSmyptLQ
Geometry isn't bone density. The trial did not show fracture prevention.
Trial: https://t.co/8cAK655SjU
Prof. Scott Forbes / Creatine For Health: https://t.co/v6TwhvpDwk
Educational, not medical advice.
#Creatine https://t.co/OoIXZMMbbR
Creatine may add to training benefits. Evidence in diagnosed sarcopenia is limited.
Prof. Scott Forbes / Creatine For Health
https://t.co/v6TwhvpDwk
Educational, not medical advice.
#Creatine #HealthyAging https://t.co/iKlTPtRvXb
A 2-yr Randomized Controlled Trial on Creatine Supplementation during Exercise for Postmenopausal Bone Health
"Two years of creatine supplementation and exercise in postmenopausal women had no effect on BMD; yet, it improved some bone geometric properties at the proximal femur."
Just more evidence that daily creatine supplementation (even at high dosages for long periods of time) cause NO greater adverse effects (markers of kidney and liver function) compared to placebo
#creatine
https://t.co/cecBPMT67P
RT @darrencandow: The SAFETY profile of creatine supplementation is EXCELLENT.
~ 10 grams of creatine every day for 2 years resulted in NO…
Jun 5, 2023 · 21 shares · 255 followersView post →
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Thomas
@gireviktmac619 · X
RT @darrencandow: The SAFETY profile of creatine supplementation is EXCELLENT.
~ 10 grams of creatine every day for 2 years resulted in NO…
Jun 5, 2023 · 21 shares · 191 followersView post →
NK
Nick Krontiris
@nick_krontiris · X
RT @darrencandow: The SAFETY profile of creatine supplementation is EXCELLENT.
~ 10 grams of creatine every day for 2 years resulted in NO…
Jun 5, 2023 · 21 shares · 19,385 followersView post →
SF
Scott Forbes
@DrCreatine · X
RT @darrencandow: The SAFETY profile of creatine supplementation is EXCELLENT.
~ 10 grams of creatine every day for 2 years resulted in NO…
Jun 5, 2023 · 21 shares · 835 followersView post →
KC
Kim Tirapelle,MS,RD,CSSD
@KimTirapelleRD · X
RT @darrencandow: The SAFETY profile of creatine supplementation is EXCELLENT.
~ 10 grams of creatine every day for 2 years resulted in NO…
Jun 5, 2023 · 21 shares · 2,451 followersView post →
AP
Assent Performance
@SteAssent · X
RT @darrencandow: The SAFETY profile of creatine supplementation is EXCELLENT.
~ 10 grams of creatine every day for 2 years resulted in NO…
Jun 5, 2023 · 21 shares · 1,810 followersView post →
DF
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X
The SAFETY profile of creatine supplementation is EXCELLENT.
~ 10 grams of creatine every day for 2 years resulted in NO greater prevalence of adverse events vs placebo in postmenopausal women
#creatine #safe #health
https://t.co/cecBPMSyih
Jun 5, 2023 · 61 likes · 21 shares · 6,729 followersView post →
Ж
Жутинић
@DusanZutinic · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 26, 2023 · 31 shares · 171 followersView post →
JN
Judy Newhouse
@newhousejw · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 26, 2023 · 31 shares · 13 followersView post →
K
KM 007
@karam_aldeeb · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 12, 2023 · 13 shares · 132 followersView post →
RV
Rob Veer
@RobVeer · X
RT @NBTiller: More evidence of creatine's benefits. A two-year randomized trial shows creatine supplementation improved bone strength (sect…
May 12, 2023 · 4 shares · 1,426 followersView post →
AC
Alpine Cols
@AlpineCols · X
RT @NBTiller: More evidence of creatine's benefits. A two-year randomized trial shows creatine supplementation improved bone strength (sect…
May 12, 2023 · 4 shares · 364 followersView post →
D
DRBH1000
@DRBH1000 · X
RT @NBTiller: More evidence of creatine's benefits. A two-year randomized trial shows creatine supplementation improved bone strength (sect…
May 12, 2023 · 4 shares · 1,337 followersView post →
ND
Nick Tiller, Ph.D.
@NBTiller · X
More evidence of creatine's benefits. A two-year randomized trial shows creatine supplementation improved bone strength (section modulus and buckling ratio) in postmenopausal women. #creatine #nutrition #strength #bone #health @MSSEonline
May 12, 2023 · 22 likes · 4 shares · 10,644 followersView post →
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 9, 2023 · 31 shares · 697 followersView post →
SC
SSG_Mat_CSCS
@afronetix · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 9, 2023 · 31 shares · 201 followersView post →
GG
Greta Compton Dip DH RCSEd aka Gretsky
@Gretsky_Compton · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 9, 2023 · 31 shares · 899 followersView post →
AP
Assent Performance
@SteAssent · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 9, 2023 · 31 shares · 1,810 followersView post →
T
Tom
@tommypiner · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 9, 2023 · 31 shares · 105 followersView post →
DF
Darren Candow, PhD, CSEP-CEP, FISSN
@darrencandow · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 9, 2023 · 31 shares · 6,729 followersView post →
CK
Cindy Kugler
@Exspec85 · X
RT @DrAndyGalpin: 2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mine…
May 8, 2023 · 31 shares · 232 followersView post →
AP
Andy Galpin, PhD
@DrAndyGalpin · X
2 year study by @darrencandow showing 10g/day of creatine (w/ exercise) in postmenopausal women did not improve bone mineral density but did enhance other markers associated w/ hip fracture risk.
Minimal adverse events, including kidney & liver health.
https://t.co/eObsjVgVNG
May 8, 2023 · 218 likes · 31 shares · 95,219 followersView post →
SS
Starting Strength
@SS_strength · X
RT @scienceforfit: A 2-year randomized controlled trial in post-menopausal women found that creatine supplementation paired with exercise h…
May 7, 2023 · 1 share · 40,934 followersView post →
MS
Mind Your Science!
@MindYourSci · X
RT @nick_krontiris: A 2-Year Randomized Controlled Trial on Creatine Supplementation during Exercise for Postmenopausal Bone Health (open a…
RT @nick_krontiris: A 2-Year Randomized Controlled Trial on Creatine Supplementation during Exercise for Postmenopausal Bone Health (open a…
May 6, 2023 · 2 shares · 6,729 followersView post →
L
LibKey
@libkey_io · X
@nick_krontiris Get access rather than a paywall: https://t.co/t3hFDG3iKD
Add https://t.co/SXSePSX5De to the DOI URL when sharing articles to promote scholarly communication
A 2-Year Randomized Controlled Trial on Creatine Supplementation during Exercise for Postmenopausal Bone Health (open access)
https://t.co/6dWUc0C6Rm
#exercise #Workout #TrainHard #GymLife #GymTime #muscle #strength #lift #nutrition #diet #supplements #supplement
May 6, 2023 · 5 likes · 2 shares · 19,385 followersView post →
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7 Reasons To Take Creatine Every Day - HEALTH
News
doi:10.1249/MSS.0000000000003202. Wax B, Kerksick CM, Jagim AR, Mayo JJ, Lyons BC, Kreider RB. Creatine for Exercise and Sports Performance, with Recovery ...