Signal Transduct Target Ther May 2023 PMID 37179335

Immunosenescence: molecular mechanisms and diseases.

Zaoqu Liu, Qimeng Liang, Yuqing Ren, Chunguang Guo, Xiaoyong Ge, Libo Wang, Quan Cheng, Peng Luo, Yi Zhang, Xinwei Han

Mentions

58
Peak: 30 in May 2023
across 6 sources since May 2023

Extended reach

126,777
potential audience

Total likes

108

Video views

125

Mentions per month

May 2023 – Aug 2023

Where it's discussed

  • X / Twitter31 posts
  • News18 articles
  • Facebook3 posts
  • Blogs3 articles
  • Reddit2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reveal an appreciation for the article's detailed examination of how immune functions decline with age, highlighted by phrases such as 'chronic inflammation' and 'major risk factors for age-related diseases.' Several posts emphasize the importance of understanding molecular mechanisms, using tone and language that suggest both respect and curiosity about its implications for health and aging research.

AgreementModerate agreement

Most discussions acknowledge the significance of immunosenescence and its role in age-related health issues, suggesting general support for the publication's focus.

InterestHigh interest

Posts indicate high interest, with mentions of its relevance to aging, chronic inflammation, and diseases, reflecting curiosity and recognition of importance.

EngagementModerate engagement

Some posts delve into key concepts like inflammaging and molecular mechanisms, showing moderate but meaningful engagement rather than superficial mentions.

ImpactModerate impact

The conversations imply awareness of the publication's potential influence on understanding aging and immune decline, though they stop short of discussing specific applications or breakthroughs.

Abstract in brief

  • Immunosenescence involves the decline of immune function with age, characterized by chronic inflammation called inflammaging, which increases susceptibility to infections, poor vaccine responses, and age-related diseases such as cancer.
  • Key features include thymic involution, imbalanced memory T cell ratios, metabolic and epigenetic changes, and the accumulation of proinflammatory senescent immune cells that worsen inflammation and disease risk.
  • Understanding the molecular mechanisms of immunosenescence is crucial for developing interventions, especially in relation to cancer, as it affects immune responses and the effectiveness of therapies in the elderly.]

Top posts

Most liked on X and Bluesky
Aging Science News
@AgingBiology · X

Immunosenescence: molecular mechanisms and diseases https://t.co/AOI6Sgz1mK

May 28, 2023 · 35 likes · 7 shares · 30,515 followers View post →
Agingdoc
@agingdoc1 · X

Immunosenescence: molecular mechanisms and diseases https://t.co/K7dLUZh9AC https://t.co/x9ezC8cHz7

May 14, 2023 · 29 likes · 4 shares · 41,347 followers View post →
Pluchino lab - Regenerative Neuroimmunology
@Pluchinolab · X

Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 29, 2023 · 23 likes · 9 shares · 4,743 followers View post →
htw
@heniek_htw · X

Immunosenescence: molecular mechanisms and diseases https://t.co/6HMmWgxgrg https://t.co/DSq7j9Dw4H

May 14, 2023 · 11 likes · 4 shares · 11,280 followers View post →
Mauro Corrado
@MauroCorradoBio · X

Immunosenescence: molecular mechanisms and diseases https://t.co/E5zxCj1sit

May 29, 2023 · 8 likes · 4 shares · 2,008 followers View post →
This is Canada
@CanadaAnimals · X

RT @agingdoc1: Immunosenescence: molecular mechanisms and diseases https://t.co/K7dLUZh9AC https://t.co/x9ezC8cHz7

May 14, 2023 · 4 shares · 21,090 followers View post →

All mentions

Feras Al Battah
@ferasalbattah · X

RT @MauroCorradoBio: Immunosenescence: molecular mechanisms and diseases https://t.co/E5zxCj1sit

Jun 11, 2023 · 4 shares · 987 followers View post →
Kavi
@Kavitha_Thirumu · X

RT @Pluchinolab: Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 30, 2023 · 9 shares · 176 followers View post →
Luis J. Castro-Vega
@LuisJaimeCastr3 · X

RT @Pluchinolab: Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 30, 2023 · 9 shares · 658 followers View post →
André Katayama Yamada
@KatayamaYamada · X

RT @MauroCorradoBio: Immunosenescence: molecular mechanisms and diseases https://t.co/E5zxCj1sit

May 29, 2023 · 4 shares · 404 followers View post →
EBRAH SSALI - PhD (Candidate)
@IBRAHSSALI1 · X

RT @Pluchinolab: Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 29, 2023 · 9 shares · 802 followers View post →
Zeeba Manavi
@Zeebamehrin · X

RT @Pluchinolab: Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 29, 2023 · 9 shares · 225 followers View post →
Victoria Hendry
@HendryVictoria · X

RT @Pluchinolab: Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 29, 2023 · 9 shares · 1,320 followers View post →
Immortality Bliss
@ImmortalityB · X

RT @AgingBiology: Immunosenescence: molecular mechanisms and diseases https://t.co/AOI6Sgz1mK

May 29, 2023 · 7 shares · 182 followers View post →
Alexis Jimenez
@AF488 · X

RT @MauroCorradoBio: Immunosenescence: molecular mechanisms and diseases https://t.co/E5zxCj1sit

May 29, 2023 · 4 shares · 65 followers View post →
Francisco J. Martínez | Psicólogo Biomédico
@Francisco_JMR9 · X

RT @Pluchinolab: Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 29, 2023 · 9 shares · 114 followers View post →
Joy Edwards-Hicks
@JEdwardsHicks · X

RT @MauroCorradoBio: Immunosenescence: molecular mechanisms and diseases https://t.co/E5zxCj1sit

May 29, 2023 · 4 shares · 524 followers View post →
Mauro Corrado
@MauroCorradoBio · X

Immunosenescence: molecular mechanisms and diseases https://t.co/E5zxCj1sit

May 29, 2023 · 8 likes · 4 shares · 2,008 followers View post →
Phenomics
@Phenomics_J · X

RT @Pluchinolab: Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 29, 2023 · 9 shares · 1,527 followers View post →
Zhilin Li
@riselin · X

RT @Pluchinolab: Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 29, 2023 · 9 shares · 94 followers View post →
Pluchino lab - Regenerative Neuroimmunology
@Pluchinolab · X

Immunosenescence: molecular mechanisms and diseases | Signal Transduction and Targeted Therapy https://t.co/exMWjZF4zt

May 29, 2023 · 23 likes · 9 shares · 4,743 followers View post →
Phenomics
@Phenomics_J · X

RT @AgingBiology: Immunosenescence: molecular mechanisms and diseases https://t.co/AOI6Sgz1mK

May 29, 2023 · 7 shares · 1,527 followers View post →
Rohit Joshi
@RohitjoshiB · X

RT @AgingBiology: Immunosenescence: molecular mechanisms and diseases https://t.co/AOI6Sgz1mK

May 28, 2023 · 7 shares · 376 followers View post →
Alexis Lomakin, Ph.D. (אל) אַלעקסיס לאָמאַקין
@Alexis_Lomakin · X

RT @AgingBiology: Immunosenescence: molecular mechanisms and diseases https://t.co/AOI6Sgz1mK

May 28, 2023 · 7 shares · 3,647 followers View post →
genomicspark
@hexomics · X

RT @AgingBiology: Immunosenescence: molecular mechanisms and diseases https://t.co/AOI6Sgz1mK

May 28, 2023 · 7 shares · 91 followers View post →
Aging Science News
@AgingBiology · X

Immunosenescence: molecular mechanisms and diseases https://t.co/AOI6Sgz1mK

May 28, 2023 · 35 likes · 7 shares · 30,515 followers View post →
Orlando_uy
@Orlando_uy · X

Immunosenescence: molecular mechanisms and diseases. Chronic inflammation is a typical phenomenon linked to immunosenescence and it is considered the major risk factor for age-related diseases. https://t.co/Ouagr4eiUR

May 22, 2023 · 691 followers View post →
Drx_Azithromycn
@Drx_Azithromycn · X

RT @agingdoc1: Immunosenescence: molecular mechanisms and diseases https://t.co/K7dLUZh9AC https://t.co/x9ezC8cHz7

May 15, 2023 · 4 shares · 223 followers View post →
This is Canada
@CanadaAnimals · X

RT @agingdoc1: Immunosenescence: molecular mechanisms and diseases https://t.co/K7dLUZh9AC https://t.co/x9ezC8cHz7

May 14, 2023 · 4 shares · 21,090 followers View post →
Nutriop Longevity
@nutriop · X

Immunosenescence: molecular mechanisms and diseases [open-access review] https://t.co/BYCQv5XOXg

May 14, 2023 · 78 followers View post →
Dr Lauren Struszczak
@LStruszczak · X

RT @agingdoc1: Immunosenescence: molecular mechanisms and diseases https://t.co/K7dLUZh9AC https://t.co/x9ezC8cHz7

May 14, 2023 · 4 shares · 623 followers View post →
Jorge Rosas
@guruesmx · X

RT @heniek_htw: Immunosenescence: molecular mechanisms and diseases https://t.co/6HMmWgxgrg https://t.co/DSq7j9Dw4H

May 14, 2023 · 4 shares · 138 followers View post →
Victoria VALPARAISO
@Orange_Atomique · X

RT @agingdoc1: Immunosenescence: molecular mechanisms and diseases https://t.co/K7dLUZh9AC https://t.co/x9ezC8cHz7

May 14, 2023 · 4 shares · 181 followers View post →
Bayar Jaff
@JaffBayar · X

RT @heniek_htw: Immunosenescence: molecular mechanisms and diseases https://t.co/6HMmWgxgrg https://t.co/DSq7j9Dw4H

May 14, 2023 · 4 shares · 607 followers View post →
Andres Felipe
@Anferupu · X

RT @heniek_htw: Immunosenescence: molecular mechanisms and diseases https://t.co/6HMmWgxgrg https://t.co/DSq7j9Dw4H

May 14, 2023 · 4 shares · 52 followers View post →
Agingdoc
@agingdoc1 · X

Immunosenescence: molecular mechanisms and diseases https://t.co/K7dLUZh9AC https://t.co/x9ezC8cHz7

May 14, 2023 · 29 likes · 4 shares · 41,347 followers View post →
htw
@heniek_htw · X

Immunosenescence: molecular mechanisms and diseases https://t.co/6HMmWgxgrg https://t.co/DSq7j9Dw4H

May 14, 2023 · 11 likes · 4 shares · 11,280 followers View post →