JACS Au May 2023 PMID 37234117

Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation.

Kathryn A Murray, Yanan Gao, Christopher A Griffiths, Nina L H Kinney, Qiongyu Guo, Matthew I Gibson, Thomas F Whale

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Mentions

58
Peak: 17 in May 2023
across 5 sources since Apr 2023

Extended reach

1,213,425
potential audience

Total likes

3,736

Video views

97,662

Mentions per month

Apr 2023 – Aug 2023

Where it's discussed

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  • YouTube2 videos
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AI synopsis

What people are saying

The overall tone demonstrates strong support and curiosity, with discussions highlighting how chemically induced extracellular ice nucleation could improve cryopreservation outcomes, especially for complex 3D structures like spheroids. Words like 'promising' and 'revolutionize' reflect enthusiasm, with participants referencing specific benefits such as reducing cell damage and expanding biomedical applications.

AgreementStrong agreement

Most discussions agree that the research offers promising advances in cell preservation techniques, emphasizing its potential benefits.

InterestHigh interest

Participants show high interest by discussing how this method could revolutionize cryopreservation and its applications in medical research.

EngagementModerate engagement

Many discuss the methodology and implications, indicating a moderate level of deep engagement with the research details.

ImpactHigh impact

The consensus suggests that this development could significantly impact fields like tissue engineering, biological storage, and reducing reliance on animal models.

Abstract in brief

  • Chemically inducing extracellular ice nucleation with soluble polysaccharides improves cryopreservation outcomes by reducing intracellular ice formation, which is damaging to cells.
  • This method is especially effective for complex 3D cell structures like spheroids, as it protects cells without needing to penetrate the cell models, unlike traditional cryoprotectants like DMSO.
  • The findings suggest that extracellular chemical nucleators could significantly advance cell banking and the use of sophisticated 3D cell models, enhancing their potential to replace animal testing and improve in vitro research.]

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Norio Nakatsuji
@norionakatsuji · X

元論文→ Murray, Gao, Griffiths, et al. Chemically induced extracellular ice nucleation reduces intracellular ice formation enabling 2D and 3D cellular cryopreservation. JACS Au. Published online April 25, 2023:jacsau.3c00056. doi: 10.1021/jacsau.3c00056 https://t.co/PlYvvGEhBU

May 7, 2023 · 22 likes · 4 shares · 15,694 followers View post →
Matt Gibson
@LabGibson · X

Our latest #team_ice (☕️

Apr 26, 2023 · 19 likes · 7 shares · 2,784 followers View post →
Phys.org
@physorg_com · X

Cool as ice: How new research is helping scientists preserve cells @warwickuni https://t.co/3wrJgCLn8l https://t.co/zd86Z0VTxN

May 2, 2023 · 10 likes · 3 shares · 1,024,246 followers View post →
JACS Au
@JACS_Au · X

Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation @LabGibson, @TF_Whale & coworkers Check it out

May 24, 2023 · 10 likes · 5 shares · 3,595 followers View post →
ぜのぱす(初代_凍結から快復)
@Xenopus007 · X

【memo】 Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation https://t.co/KSzmosjZoW

May 7, 2023 · 1 like · 851 followers View post →
Jairo Santos
@JairoSa69292344 · X

Elon Musk lança INTELIGÊNCIA ARTIFICIAL e busca a AGI | IA de Harvard d... https://t.co/9HzzkXoWTp via @YouTube

Jul 17, 2023 · 1 like · 8 followers View post →

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Jairo Santos
@JairoSa69292344 · X

Elon Musk lança INTELIGÊNCIA ARTIFICIAL e busca a AGI | IA de Harvard d... https://t.co/9HzzkXoWTp via @YouTube

Jul 17, 2023 · 1 like · 8 followers View post →
Sabine Flitsch
@FlitschSabine · X

RT @JACS_Au: Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservati…

May 25, 2023 · 5 shares · 543 followers View post →
Toyota_Group_Komaba
@KomaToug · X

RT @JACS_Au: Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservati…

May 24, 2023 · 5 shares · 668 followers View post →
Nina Kinney
@Other_Nina · X

RT @JACS_Au: Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservati…

May 24, 2023 · 5 shares · 152 followers View post →
Matt Gibson
@LabGibson · X

RT @JACS_Au: Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservati…

May 24, 2023 · 5 shares · 2,784 followers View post →
Wasiu Lawal
@DrWasiuLawal · X

RT @JACS_Au: Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservati…

May 24, 2023 · 5 shares · 545 followers View post →
JACS Au
@JACS_Au · X

Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation @LabGibson, @TF_Whale & coworkers Check it out

May 24, 2023 · 10 likes · 5 shares · 3,595 followers View post →
NP AGARWAL世界一フォローを目指しますAiming best in world.
@np_grwl · X

RT @physorg_com: Cool as ice: How new research is helping scientists preserve cells @warwickuni https://t.co/3wrJgCLn8l https://t.co/zd86Z0…

May 11, 2023 · 3 shares · 1,793 followers View post →
Ryuta Koyama
@ryuta_koyama · X

Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation | JACS Au https://t.co/AWD5lcuNx9

May 7, 2023 · 384 followers View post →
Akane Kawaguchi
@hoyako · X

RT @norionakatsuji: 元論文→ Murray, Gao, Griffiths, et al. Chemically induced extracellular ice nucleation reduces intracellular ice formation…

May 7, 2023 · 4 shares · 387 followers View post →
ぜのぱす(初代_凍結から快復)
@Xenopus007 · X

【memo】 Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation https://t.co/KSzmosjZoW

May 7, 2023 · 1 like · 851 followers View post →
とき
@hpcm20 · X

RT @norionakatsuji: 元論文→ Murray, Gao, Griffiths, et al. Chemically induced extracellular ice nucleation reduces intracellular ice formation…

May 7, 2023 · 4 shares · 1,202 followers View post →
Shigeru Tanaka
@ShigTanak · X

RT @norionakatsuji: 元論文→ Murray, Gao, Griffiths, et al. Chemically induced extracellular ice nucleation reduces intracellular ice formation…

May 7, 2023 · 4 shares · 5 followers View post →
Norio Nakatsuji
@norionakatsuji · X

元論文→ Murray, Gao, Griffiths, et al. Chemically induced extracellular ice nucleation reduces intracellular ice formation enabling 2D and 3D cellular cryopreservation. JACS Au. Published online April 25, 2023:jacsau.3c00056. doi: 10.1021/jacsau.3c00056 https://t.co/PlYvvGEhBU

May 7, 2023 · 22 likes · 4 shares · 15,694 followers View post →
Wafik S. El-Deiry, MD, PhD, FACP
@weldeiry · X

Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation https://t.co/llcmgufNAn

May 2, 2023 · 18,499 followers View post →
Phys.org
@physorg_com · X

Cool as ice: How new research is helping scientists preserve cells @warwickuni https://t.co/3wrJgCLn8l https://t.co/zd86Z0VTxN

May 2, 2023 · 10 likes · 3 shares · 1,024,246 followers View post →
Phys.org Chemistry
@physorg_chem · X

RT @physorg_com: Cool as ice: How new research is helping scientists preserve cells @warwickuni https://t.co/3wrJgCLn8l https://t.co/zd86Z0…

May 2, 2023 · 3 shares · 7,191 followers View post →
Ken Gusler
@kgusler · X

Chemically Induced Extracellular Ice Nucleation Reduces Intracellular Ice Formation Enabling 2D and 3D Cellular Cryopreservation - https://t.co/abTfrxpDvm

May 2, 2023 · 20,007 followers View post →
BioMedSci Warwick
@BMSatWarwick · X

RT @LabGibson: Our latest #team_ice (☕️

Apr 27, 2023 · 7 shares · 813 followers View post →
Amy Godfrey
@AmyGodfrey23 · X

RT @LabGibson: Our latest #team_ice (☕️

Apr 26, 2023 · 7 shares · 118 followers View post →
Nina Kinney
@Other_Nina · X

RT @LabGibson: Our latest #team_ice (☕️

Apr 26, 2023 · 7 shares · 152 followers View post →
Maria Chiara Arno
@mchiara_arno · X

RT @LabGibson: Our latest #team_ice (☕️

Apr 26, 2023 · 7 shares · 716 followers View post →
Warwick Chemistry
@warwickchem · X

RT @LabGibson: Our latest #team_ice (☕️

Apr 26, 2023 · 7 shares · 4,884 followers View post →
Sabine Flitsch
@FlitschSabine · X

RT @LabGibson: Our latest #team_ice (☕️

Apr 26, 2023 · 7 shares · 543 followers View post →
Matt Gibson
@LabGibson · X

Our latest #team_ice (☕️

Apr 26, 2023 · 19 likes · 7 shares · 2,784 followers View post →