PubHawk
Commun Biol May 2023 PMID 37248282

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins.

Brennan Abanades, Wing Ki Wong, Fergus Boyles, Guy Georges, Alexander Bujotzek, Charlotte M Deane

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Mentions

23
Peak: 9 in May 2023
across 2 sources since Nov 2022

Extended reach

201,975
potential audience

Total likes

46

Video views

38

Mentions per month

Nov 2022 – Oct 2024

Where it's discussed

  • X / Twitter22 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions highlight the technical superiority of ImmuneBuilder, with many emphasizing its faster and more accurate predictions compared to prior models, as seen in comments about 'outperforming AlphaFold' and 'supporting research.' Users use positive language like 'game changer' and 'important development' to convey recognition of its potential influence in immunology and drug discovery, reflecting high interest and moderate impact perceptions.

AgreementModerate agreement

Most discussions reflect strong support and positive acknowledgment of the publication's advancements, with phrases like 'accurately predict' and 'outperform existing tools' indicating broad agreement.

InterestHigh interest

Participants demonstrate high curiosity, frequently mentioning technical details, such as the models' speed and accuracy, showing they find the research engaging.

EngagementModerate engagement

The discussions include references to related topics like immunotherapy, biotherapeutics, and existing models, showing a meaningful level of engagement beyond surface-level mentions.

ImpactModerate impact

While some express optimism about the potential applications in medicine and research, the overall tone indicates a recognition of moderate but important scientific impact rather than revolutionary change.

Abstract in brief

  • ImmuneBuilder is a set of deep learning models designed to accurately and quickly predict the structures of immune proteins like antibodies, nanobodies, and T-cell receptors, which are important for understanding immune responses and developing biotherapeutics.
  • The models outperform existing tools such as AlphaFold2 and AlphaFoldMultimer in both accuracy and speed, providing detailed structural predictions including error estimates for individual residues.
  • ImmuneBuilder is freely accessible through download and a web server, and also offers structural models for a large database of antibody sequences, supporting research and drug development in immunology.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Kato
@oxkawaka · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins https://t.co/sek2ajCdVL

May 30, 2023 · 16 likes · 2 shares · 5,820 followers View post →
CAR-TCR
@CAR_TCell · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins: https://t.co/xtvhstmUr5 #CARTCR #immunotherapy

Jun 8, 2023 · 10 likes · 4 shares · 4,370 followers View post →
bioRxiv Bioinfo
@biorxiv_bioinfo · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins. https://t.co/K4TKkXIC43 #biorxiv_bioinfo

Nov 5, 2022 · 7 likes · 18,171 followers View post →
hashem
@hashemkoohy · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins | Communications Biology https://t.co/cQxYoPSNEr

May 30, 2023 · 5 likes · 4 shares · 765 followers View post →
Oxford Protein Informatics Group (OPIG)
@OPIGlets · X

Immunebuilder: deep-learning models for predicting the structures of immune proteins (also talk) @brennanaba Paired Antibody Sequence Generation: A Deep Generative Language Model for the Creation of Highly Developable Libraries @oliverturnbull1 2/4

Jul 24, 2023 · 3 likes · 2,133 followers View post →
OxASN: The Oxford Antigen Specificity Network
@Ox_T_Cell_ASN · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins | Communications Biology https://t.co/WWCgCAPZYo

May 30, 2023 · 3 likes · 351 followers View post →

All mentions

manu
@weakcoalgebra · X

RT @CommsBio: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins https://t.co/oHCxVmNblR

Oct 13, 2024 · 1 share · 169 followers View post →
Communications Biology
@CommsBio · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins https://t.co/oHCxVmNblR

Oct 10, 2024 · 1 like · 1 share · 11,254 followers View post →
Oxford Protein Informatics Group (OPIG)
@OPIGlets · X

Immunebuilder: deep-learning models for predicting the structures of immune proteins (also talk) @brennanaba Paired Antibody Sequence Generation: A Deep Generative Language Model for the Creation of Highly Developable Libraries @oliverturnbull1 2/4

Jul 24, 2023 · 3 likes · 2,133 followers View post →
fangxiang
@Realorientation · X

RT @CAR_TCell: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins: https://t.co/xtvhstmUr5 #CARTCR #immun…

Jun 9, 2023 · 4 shares · 16 followers View post →
lbgbox
@lbgbox · X

RT @CAR_TCell: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins: https://t.co/xtvhstmUr5 #CARTCR #immun…

Jun 9, 2023 · 4 shares · 52 followers View post →
CancerLinks 
@CancerLinks · X

RT @CAR_TCell: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins: https://t.co/xtvhstmUr5 #CARTCR #immun…

Jun 8, 2023 · 4 shares · 97 followers View post →
John Kenten
@JohnKenten · X

RT @CAR_TCell: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins: https://t.co/xtvhstmUr5 #CARTCR #immun…

Jun 8, 2023 · 4 shares · 576 followers View post →
CAR-TCR
@CAR_TCell · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins: https://t.co/xtvhstmUr5 #CARTCR #immunotherapy

Jun 8, 2023 · 10 likes · 4 shares · 4,370 followers View post →
Pirater-un-compte-fb.com
@UnPirater · X

https://t.co/mcJbNyjOsx https://t.co/bNVlY5w0rF https://t.co/OqMDVg1NDO #twitter #facebook #metaverse #trump #joebiden #usa #war #russia #ukraine #putine #stopthewar #nature #photo #vegan #lgbt #trump2024

Jun 1, 2023 · 1,657 followers View post →
Anjali Kusumbe
@KusumbeLab · X

RT @hashemkoohy: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins | Communications Biology https://t.co…

May 31, 2023 · 4 shares · 2,133 followers View post →
John Andrew Todd
@ProfJohnATodd · X

RT @hashemkoohy: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins | Communications Biology https://t.co…

May 31, 2023 · 4 shares · 1,023 followers View post →
Adrian Liston
@LabListon · X

RT @hashemkoohy: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins | Communications Biology https://t.co…

May 31, 2023 · 4 shares · 11,479 followers View post →
Hoffman
@SPDFHoffman · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins. Deep learning models trained to accurately predict the structure of antibodies, nanobodies, and T-Cell receptors. https://t.co/lp0duhELja #science #medicine #Immunology

May 31, 2023 · 8 followers View post →
Malcolm Sim
@mjwsim · X

RT @hashemkoohy: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins | Communications Biology https://t.co…

May 30, 2023 · 4 shares · 1,822 followers View post →
hashem
@hashemkoohy · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins | Communications Biology https://t.co/cQxYoPSNEr

May 30, 2023 · 5 likes · 4 shares · 765 followers View post →
OxASN: The Oxford Antigen Specificity Network
@Ox_T_Cell_ASN · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins | Communications Biology https://t.co/WWCgCAPZYo

May 30, 2023 · 3 likes · 351 followers View post →
know thyself（子豚のオリバー)
@thyself_know · X

RT @oxkawaka: ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins https://t.co/sek2ajCdVL

May 30, 2023 · 2 shares · 1,230 followers View post →
Kato
@oxkawaka · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins https://t.co/sek2ajCdVL

May 30, 2023 · 16 likes · 2 shares · 5,820 followers View post →
hashem
@hashemkoohy · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins. | bioRxiv https://t.co/U56G8UGRsx

Nov 7, 2022 · 765 followers View post →
Helio Rocha
@_elioRocha · X

#bioRxiv ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins. #bioinfo https://t.co/muRX1wOs1Y

Nov 5, 2022 · 609 followers View post →
bioRxiv Bioinfo
@biorxiv_bioinfo · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins. https://t.co/K4TKkXIC43 #biorxiv_bioinfo

Nov 5, 2022 · 7 likes · 18,171 followers View post →
bioRxiv
@biorxivpreprint · X

ImmuneBuilder: Deep-Learning models for predicting the structures of immune proteins. https://t.co/CmQHJYuCns #bioRxiv

Nov 5, 2022 · 1 like · 137,346 followers View post →