Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natureneuroscience. Cheers to all! https://t.co/AlxH9zDLaz 15/
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB.
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Jun 2023 – Oct 2025Where it's discussed
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AI synopsis
What people are saying
Several discussions emphasize the disconnect between the beneficial properties of psychedelics and their hallucinogenic effects, referring to this differentiation as crucial for potential antidepressant applications. Phrases such as 'fascinating study' and 'interesting idea' reflect excitement and engagement, while requests for further discussions about the research highlight the community's interest in deepening their understanding.
Most discussions express a moderate level of agreement with the conclusions of the publication, suggesting that psychedelics have significant potential for promoting neuroplasticity.
The discussions show strong curiosity regarding the findings and implications of the research, reflecting a high level of engagement with the topic.
While the conversations do cover the implications and methodology of the study, they tend to lean more towards sharing the publication rather than in-depth analysis.
Many individuals believe the findings of this research could have a substantial influence on future antidepressant development and understanding of psychedelics.
Abstract in brief
- Psychedelics like LSD and psilocin show stronger binding to the TrkB receptor than traditional antidepressants, leading to quick and lasting antidepressant effects.
- Their effects on neuroplasticity and mood improvements in mice are linked to TrkB signaling and promote brain-derived neurotrophic factor (BDNF) activity, but don’t rely on serotonin 2A receptor activation.
- This research suggests that developing new antidepressants that enhance TrkB activity without affecting serotonin pathways could achieve the mood-lifting benefits of psychedelics while avoiding hallucinations.
Top posts
Most liked on X and BlueskyFascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link: https://t.co/ZPVTkk4YcP https://t.co/LSPOx9NLqY
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB @RafaelMoliner @p_casarotto @UH_Neuro @HkiBrainMind & @castren_eero | @NatureNeuro https://t.co/E3m2or8x9i https://t.co/et4Jc0TJa9
サイケデリクスの強力な抗うつ効果の詳細なメカニズムがついに明らかになったか? Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/ap1tjUccap
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/7chzKpsOZA
@analog_ashley https://t.co/KskatGAOCl
All mentions
Psychedelics Promote Brain Plasticity by Binding to TrkB receptors
Neuroplasticity Induced by Psychedelics: Insights and Implications
Luke Thomas discusses the role of psychedelics in neuroplasticity and their potential therapeutic benefits for various psychiatric conditions. Learn about the neuropharmacology involved and how substances like…
Understanding the Impact of LSD on Brain Plasticity and Mood
This video explores how psychedelics like LSD bind to the TrkB receptor, enhancing neuroplasticity and offering rapid antidepressant effects. Discover the implications of this research for future antidepressant…
@hanna_pssd @NTFabiano not once said ssri‘s was referring to this study: https://t.co/vdXWuLUZJ6
Find Rafael's publication here: Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience [https://t.co/knW3vDXpF6]
RT @Neurons2Nirvana: I just posted "Abstract* | #Psychedelics promote #plasticity by directly #binding to #BDNF #receptor #TrkB | Nature #N…
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/3vCqlrVOVP "plasticity-promoting effects of psychedelics may be dissociable from their hallucinogenic effects"
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB www.nature.com/articles/s41... "plasticity-promoting effects of psychedelics may be dissociable from their hallucinogenic effects"
@etoEMIdato https://t.co/8qnjGFcnys
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/2kRXN73m4p
@analog_ashley https://t.co/KskatGAOCl
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB #brain https://t.co/9HS0uXUbqF
RT @cg_dr: Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/w7Rm4V2ift
@alieninsect @KONCRETE hey Andrew are you planning on discussing this new BDNF paper? https://t.co/wjBF6GhD0z please consider this a request if that's helpful! ;)
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB - Nature Neuroscience https://t.co/6y2uls7Gsd
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/yGupdNzVfV https://t.co/d5OjRLYLNB
RT @MASogorb: ¿Separar los efectos positivos de los negativos en drogas psicodélicas para crear antidepresivos? https://t.co/ebj51ff4zd Más…
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/TcAoN5Rb10
¿Separar los efectos positivos de los negativos en drogas psicodélicas para crear antidepresivos? https://t.co/ebj51ff4zd Más información: Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/XVlShPO8rO
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/w7Rm4V2ift
サイケデリクスの強力な抗うつ効果の詳細なメカニズムがついに明らかになったか? Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/ap1tjUccap
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/3vCqlrVOVP "antidepressant and #plasticity-promoting effects of #psychedelics may be dissociable from their hallucinogenic effects"; #neuroplasticity
RT @agingdoc1: Psychedelics promote plasticity by directly binding to BDNF receptor TrkB @RafaelMoliner @p_casarotto @UH_Neuro @HkiBrainM…
RT @agingdoc1: Psychedelics promote plasticity by directly binding to BDNF receptor TrkB @RafaelMoliner @p_casarotto @UH_Neuro @HkiBrainM…
RT @APRAresearch: Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/J4ZZEevdKZ
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/J4ZZEevdKZ
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/nUhBxvTwKl
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
LSD & psilocin directly bind to TrkB w/ affinities 1,000-fold higher than... other antidepressants. TrkB, the receptor for BDNF (brain-derived neurotrophic factor)... new growth in both baby & mature neurons... fast & persistent antidepressant effects... https://t.co/Ng56cjx3Ld https://t.co/ieQJ93BFDX
RT @MarkOldhamMD: Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link:…
Fascinating study suggests that the antidepressant effects of LSD & psilocybin are independent of 5-HT2a activity. Link: https://t.co/ZPVTkk4YcP https://t.co/LSPOx9NLqY
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB @RafaelMoliner @p_casarotto @UH_Neuro @HkiBrainMind & @castren_eero | @NatureNeuro https://t.co/E3m2or8x9i https://t.co/et4Jc0TJa9
I suspect that this is going to send me down a rabbit hole of references. Interesting idea. Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/3YAOEACP9g
RT @daforerog: Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/ClyNhtBri0
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/ClyNhtBri0
I just posted "Psychedelics promote plasticity by directly binding to BDNF receptor TrkB" on Reddit https://t.co/ZGEmhCSvsJ
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/XwGUJW6FBn
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB https://t.co/5vCbcEe3kX
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
I just posted "Abstract* | #Psychedelics promote #plasticity by directly #binding to #BDNF #receptor #TrkB | Nature #Neuroscience (@NatureNeuro) [Jun 2023] #LSD #psilocin #fluoxetine #ketamine #Neuroplasticity" on Reddit https://t.co/cuDSI5lwjP
@ferenstein @BellevueDoc ICYMI: #Psychedelics promote #plasticity by directly binding to #BDNF receptor #TrkB: https://t.co/NgXn3PTDmd
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/7EQlO78TAC
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
RT @BenLewisMD: Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/7chzKpsOZA
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB | Nature Neuroscience https://t.co/7chzKpsOZA
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB - Nature Neuroscience via BrainSights for iOS https://t.co/BkRRfrdHGy
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
RT @RafaelMoliner: Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natu…
Our paper “Psychedelics promote plasticity by directly binding to BDNF receptor TrkB” was published in open access @natureneuroscience. Cheers to all! https://t.co/AlxH9zDLaz 15/