New in @AJPCell: Murugathasan et al. found that chronic moderate #exercise can influence the inflammatory responses of #macrophages by reprogramming their metabolic & #epigenetic landscape. https://t.co/4ankW6ufXQ @MHRC_YorkU @YorkUHealth @aabdulsater #Mitochondria https://t.co/y1tryTv21Q
Moderate exercise induces trained immunity in macrophages.
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Jun 2023 – Aug 2025Where it's discussed
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What people are saying
The discussions around this publication frequently emphasize the significance of moderate exercise for boosting immunity, using words like 'important,' 'beneficial,' and phrases like 'may help immunity' to express support. Several comments delve into mechanistic details, such as reprogramming macrophage metabolism and epigenetic landscapes, which show a deep engagement with the scientific concepts and suggest recognition of the research’s potential to influence future health strategies.
Most posts strongly support the findings, emphasizing the positive role of moderate exercise in immune response and training macrophages, often using affirming words like 'important,' 'beneficial,' and 'increases.'
Discussions demonstrate high interest by highlighting the significance of the research, with comments such as 'The importance of exercise increases every day' and calling the findings a 'game changer,' reflecting curiosity and perceived relevance.
Many posts delve into technical details, referencing mechanisms like metabolism, mitochondrial function, and epigenetics, indicating deep engagement with the scientific content.
Although some users suggest it could influence health practices and medical understanding positively, the perceived impact is slightly moderate as discussions mainly focus on potential rather than immediate, broad societal change.
Abstract in brief
- Moderate exercise causes long-lasting changes in macrophages, the immune cells responsible for inflammation, by altering their metabolism and how their genes are accessed (epigenetic landscape).
- These changes lead to a reduction in inflammatory responses, such as decreased activation of inflammatory pathways and increased expression of anti-inflammatory (M2-like) genes, ultimately helping prevent inflammation-related diseases.
- The process involves improved mitochondrial function, increased reliance on oxygen-based energy production, and modifications in chromatin accessibility, which together help macrophages respond more efficiently to threats while minimizing tissue damage.
Top posts
Most liked on X and Bluesky運動が炎症に効くのって何でなの? 中程度の運動は骨髄由来マクロファージにおいて呼吸、グルコースの代謝、DNAアクセスなどの再構築を促すことで炎症性遺伝子の発現や活性酸素の産生を抑制するらしい どのワークアウトが特にいいとかも気になるな https://t.co/dn9sWezjjQ
Chronic moderate exercise can influence the inflammatory responses of macrophages by reprogramming their metabolic and epigenetic landscape. M Murugathasan et al. Am J Physiol Cell Physiol 2023 Jun 12 https://t.co/1G2bcNHWnC …trained immunity https://t.co/HvIFKNW1uv
Another reminder to get to the gym, Mayoorey Murugathasan et al. authored today's #ArticleinPress Moderate exercise induces trained immunity in macrophages: https://t.co/uzlSDucgo4 @YorkUHealth #Exercise #Inflammation https://t.co/zQq0LmG5MC
Moderate exercise induces trained immunity in macrophages https://t.co/skoctiyI4F @AJPCellPhys https://t.co/OdaNPAv6ZU
The importance of #exercise increases every day as this #ArtilceinPress shows it may also help immunity. Moderate exercise induces trained immunity in macrophages (Mayoorey Murugathasan et al.): https://t.co/vtzcAquR9m @MHRC_YorkU #Inflammation #Mitochondria https://t.co/s06YDBzihS
All mentions
How 30 Days of Lifestyle Changes Reduce Inflammation Effectively
Moderate exercise induces long-lasting changes in macrophages by altering their metabolism and gene accessibility, leading to reduced inflammation and helping prevent inflammation-related diseases.
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Moderate exercise induces long-lasting changes in macrophages, immune cells responsible for inflammation, by altering their metabolism and gene access, leading to decreased inflammation and potential prevention of…
Moderate Exercise Enhances Immune Response and Reduces Inflammation
This video explores groundbreaking research showing that moderate exercise induces long-lasting changes in macrophages, immune cells responsible for inflammation. These changes improve their function, reduce…
Watch the full video here: https://t.co/wrhrdQDDYL
https://t.co/RRdXnIeDGY
RT @AJPCellPhys: The importance of #exercise increases every day as this #ArtilceinPress shows it may also help immunity. Moderate exercise…
RT @AJPCellPhys: The importance of #exercise increases every day as this #ArtilceinPress shows it may also help immunity. Moderate exercise…
RT @AJPCellPhys: The importance of #exercise increases every day as this #ArtilceinPress shows it may also help immunity. Moderate exercise…
The importance of #exercise increases every day as this #ArtilceinPress shows it may also help immunity. Moderate exercise induces trained immunity in macrophages (Mayoorey Murugathasan et al.): https://t.co/vtzcAquR9m @MHRC_YorkU #Inflammation #Mitochondria https://t.co/s06YDBzihS
RT @APSPhysiology: .@AJPCellPhys article (https://t.co/bDuqQx4rtj) is cited in “Cardio Curbs Excessive Inflammation in Surprising Ways” fro…
RT @AJPCellPhys: Another reminder to get to the gym, Mayoorey Murugathasan et al. authored today's #ArticleinPress Moderate exercise induce…
Another reminder to get to the gym, Mayoorey Murugathasan et al. authored today's #ArticleinPress Moderate exercise induces trained immunity in macrophages: https://t.co/uzlSDucgo4 @YorkUHealth #Exercise #Inflammation https://t.co/zQq0LmG5MC
Researchers at @UniOfYork have expanded the current knowledge on the beneficial role of exercise on the body’s response to inflammation, indicating that this may increase the production of macrophages (white blood cells that kill off infections) https://t.co/IZ5glG6rkp
RT @APSPhysiology: .@AJPCellPhys article (https://t.co/bDuqQx4rtj) is cited in “Cardio Curbs Excessive Inflammation in Surprising Ways” fro…
RT @APSPhysiology: .@AJPCellPhys article (https://t.co/bDuqQx4rtj) is cited in “Cardio Curbs Excessive Inflammation in Surprising Ways” fro…
.@AJPCellPhys article (https://t.co/bDuqQx4rtj) is cited in “Cardio Curbs Excessive Inflammation in Surprising Ways” from @PsychToday: https://t.co/LsoP5uMXYr CC: @AJPCellPhysEIC
RT @immUNode: 運動が炎症に効くのって何でなの? 中程度の運動は骨髄由来マクロファージにおいて呼吸、グルコースの代謝、DNAアクセスなどの再構築を促すことで炎症性遺伝子の発現や活性酸素の産生を抑制するらしい どのワークアウトが特にいいとかも気になるな https…
Moderate exercise induces trained immunity in macrophages | American Journal of Physiology-Cell Physiology https://t.co/NwUOuAAs6K
RT @immUNode: 運動が炎症に効くのって何でなの? 中程度の運動は骨髄由来マクロファージにおいて呼吸、グルコースの代謝、DNAアクセスなどの再構築を促すことで炎症性遺伝子の発現や活性酸素の産生を抑制するらしい どのワークアウトが特にいいとかも気になるな https…
RT @immUNode: 運動が炎症に効くのって何でなの? 中程度の運動は骨髄由来マクロファージにおいて呼吸、グルコースの代謝、DNAアクセスなどの再構築を促すことで炎症性遺伝子の発現や活性酸素の産生を抑制するらしい どのワークアウトが特にいいとかも気になるな https…
RT @immUNode: 運動が炎症に効くのって何でなの? 中程度の運動は骨髄由来マクロファージにおいて呼吸、グルコースの代謝、DNAアクセスなどの再構築を促すことで炎症性遺伝子の発現や活性酸素の産生を抑制するらしい どのワークアウトが特にいいとかも気になるな https…
運動が炎症に効くのって何でなの? 中程度の運動は骨髄由来マクロファージにおいて呼吸、グルコースの代謝、DNAアクセスなどの再構築を促すことで炎症性遺伝子の発現や活性酸素の産生を抑制するらしい どのワークアウトが特にいいとかも気になるな https://t.co/dn9sWezjjQ
RT @Osteoporosis_NL: Chronic moderate exercise can influence the inflammatory responses of macrophages by reprogramming their metabolic and…
RT @agingdoc1: Moderate exercise induces trained immunity in macrophages https://t.co/skoctiyI4F @AJPCellPhys https://t.co/OdaNPAv6ZU
RT @Osteoporosis_NL: Chronic moderate exercise can influence the inflammatory responses of macrophages by reprogramming their metabolic and…
RT @agingdoc1: Moderate exercise induces trained immunity in macrophages https://t.co/skoctiyI4F @AJPCellPhys https://t.co/OdaNPAv6ZU
RT @Osteoporosis_NL: Chronic moderate exercise can influence the inflammatory responses of macrophages by reprogramming their metabolic and…
RT @Osteoporosis_NL: Chronic moderate exercise can influence the inflammatory responses of macrophages by reprogramming their metabolic and…
RT @Osteoporosis_NL: Chronic moderate exercise can influence the inflammatory responses of macrophages by reprogramming their metabolic and…
として機能する白血球ですが、時として癌や自己免疫疾患の原因となる過剰な炎症を起こすこともあります。適度な運動が、骨髄内のマクロファージ前駆体の代謝およびエピジェネティックな調節を再プログラムすることによって、過剰な炎症反応を和らげることが明らかになりましたhttps://t.co/ojm1SfjBQ7
Chronic moderate exercise can influence the inflammatory responses of macrophages by reprogramming their metabolic and epigenetic landscape. M Murugathasan et al. Am J Physiol Cell Physiol 2023 Jun 12 https://t.co/1G2bcNHWnC …trained immunity https://t.co/HvIFKNW1uv
Moderate exercise induces trained immunity in macrophages https://t.co/skoctiyI4F @AJPCellPhys https://t.co/OdaNPAv6ZU
Moderate exercise induces trained immunity in macrophages https://t.co/e919jlipLQ https://t.co/BLo4SFY4q5
RT @APSPublications: New in @AJPCell: Murugathasan et al. found that chronic moderate #exercise can influence the inflammatory responses of…
New in @AJPCell: Murugathasan et al. found that chronic moderate #exercise can influence the inflammatory responses of #macrophages by reprogramming their metabolic & #epigenetic landscape. https://t.co/4ankW6ufXQ @MHRC_YorkU @YorkUHealth @aabdulsater #Mitochondria https://t.co/y1tryTv21Q