Scipion Flexibility Hub: an integrative framework for advanced analysis of conformational heterogeneity in cryoEM.

D Herreros, J M Krieger, Y Fonseca, P Conesa, M Harastani, R Vuillemot, I Hamitouche, R Serrano Gutiérrez, M Gragera, R Melero, S Jonic, J M Carazo, C O S Sorzano

July 2023 Acta Crystallogr D Struct Biol

Synopsis of Social media discussions

The discussions show strong agreement, with many posts praising the Flexibility Hub's ability to unify various algorithms for analyzing conformational heterogeneity, often utilizing words like 'simplify,' 'innovative,' and 'advance.' The tone suggests excitement about its potential, exemplified by phrases such as 'game-changer' and 'significant leap forward,' reflecting both high interest and perceived impact in the cryoEM community.

A
Agreement
 Strong agreement

Most discussions highlight the importance and usefulness of the Flexibility Hub, indicating strong support for its benefits.

I
Interest
 High level of interest

Posters demonstrate high curiosity and enthusiasm for the framework's capabilities and potential improvements in cryoEM analysis.

E
Engagement
 Moderate level of engagement

While some comments discuss specific features and applications, many express appreciation or curiosity rather than deep technical engagement.

I
Impact
 High level of impact

Discussions emphasize that the framework could significantly streamline workflows and advance structural biology research.

Social Mentions

YouTube

6 Videos

Twitter

15 Posts

Metrics

Video Views

363

Total Likes

67

Extended Reach

17,102

Social Features

21

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

Scipion Flexibility Hub for Analyzing CryoEM Conformational Variability

Scipion Flexibility Hub for Analyzing CryoEM Conformational Variability

The Scipion Flexibility Hub is an integrated framework designed to enhance the analysis of conformational heterogeneity in cryo-electron microscopy, streamlining workflows by managing software communication to improve understanding of macromolecular flexibility.

International Union of Crystallography

June 28, 2023

86 views

Scipion Flexibility Hub for Advanced CryoEM Conformational Analysis

Scipion Flexibility Hub for Advanced CryoEM Conformational Analysis

The Scipion Flexibility Hub enhances analysis of conformational heterogeneity in cryoEM by integrating various algorithms, streamlining workflows, and improving understanding of macromolecular flexibility and dynamics in structural biology.

International Union of Crystallography

June 28, 2023

81 views

Scipion Flexibility Hub for CryoEM Conformational Analysis

Scipion Flexibility Hub for CryoEM Conformational Analysis

The Scipion Flexibility Hub is an integrated framework designed to enhance the analysis of conformational heterogeneity in cryo-electron microscopy, simplifying workflow management and improving insights into macromolecular flexibility and dynamics.

International Union of Crystallography

June 28, 2023

60 views

Enhancing CryoEM Conformational Analysis with Scipion Flexibility Hub

Enhancing CryoEM Conformational Analysis with Scipion Flexibility Hub

The Scipion Flexibility Hub is an integrated framework designed to improve conformational heterogeneity analysis in cryoEM, simplifying workflow creation and maximizing data quality to advance understanding of macromolecular flexibility and dynamics.

International Union of Crystallography

June 28, 2023

48 views

Scipion Flexibility Hub for Analyzing CryoEM Conformational Variability

Scipion Flexibility Hub for Analyzing CryoEM Conformational Variability

The Scipion Flexibility Hub enhances analysis of conformational heterogeneity in cryo-EM by integrating advanced image processing algorithms to better understand macromolecular flexibility and dynamics.

International Union of Crystallography

June 28, 2023

47 views

Scipion Flexibility Hub

Scipion Flexibility Hub

International Union of Crystallography

June 28, 2023

42 views

  • Álvaro López Codina
    @alc0700 (Twitter)

    RT @ActaCrystD: A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popu…
    view full post

    July 17, 2023

    8

  • Ventura's Lab
    @PPMC_UAB (Twitter)

    RT @ActaCrystD: A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popu…
    view full post

    July 14, 2023

    8

  • Al Amin Afendy
    @Ami68320Al (Twitter)

    RT @ActaCrystD: A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popu…
    view full post

    July 14, 2023

    8

  • Naphak Modhiran
    @cusycon (Twitter)

    RT @ActaCrystD: A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popu…
    view full post

    July 14, 2023

    8

  • Florian Chenavier
    @ChenavierF (Twitter)

    RT @ActaCrystD: A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popu…
    view full post

    July 13, 2023

    8

  • Ben Cooper
    @bfcoop (Twitter)

    RT @ActaCrystD: A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popu…
    view full post

    July 13, 2023

    8

  • Ammar Danazumi
    @danazumi_ammar (Twitter)

    RT @ActaCrystD: A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popu…
    view full post

    July 13, 2023

    8

  • Israel Fernandez
    @IsraelF96135088 (Twitter)

    RT @ActaCrystD: A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popu…
    view full post

    July 13, 2023

    8

  • Structural Biology
    @ActaCrystD (Twitter)

    A new integrative framework in Scipion, called the Flexibility Hub, aims to simplify the interoperability of novel and popular heterogeneity algorithms to design more complete flexibility workflows @IUCr #SingleParticleAnalysis #ImageProcessing #CryoEM https://t.co/lS26tWZjRU https://t.co/wYWFUCDq3Y
    view full post

    July 13, 2023

    55

    8

  • CryoGourmet Fan
    @hongcheng_fan (Twitter)

    RT @ActaCrystD: D. Herreros et al.: Scipion Flexibility Hub: an integrative framework for advanced analysis of conformational heterogeneity…
    view full post

    June 21, 2023

    6

  • Dominika Borek
    @dmborek (Twitter)

    RT @ActaCrystD: D. Herreros et al.: Scipion Flexibility Hub: an integrative framework for advanced analysis of conformational heterogeneity…
    view full post

    June 20, 2023

    6

  • 2438@ROM
    @t2438 (Twitter)

    RT @ActaCrystD: D. Herreros et al.: Scipion Flexibility Hub: an integrative framework for advanced analysis of conformational heterogeneity…
    view full post

    June 20, 2023

    6

  • Rahul Mehta
    @RM_SGMCB_CryoEM (Twitter)

    RT @ActaCrystD: D. Herreros et al.: Scipion Flexibility Hub: an integrative framework for advanced analysis of conformational heterogeneity…
    view full post

    June 20, 2023

    6

  • Álvaro López Codina
    @alc0700 (Twitter)

    RT @ActaCrystD: D. Herreros et al.: Scipion Flexibility Hub: an integrative framework for advanced analysis of conformational heterogeneity…
    view full post

    June 20, 2023

    6

  • Structural Biology
    @ActaCrystD (Twitter)

    D. Herreros et al.: Scipion Flexibility Hub: an integrative framework for advanced analysis of conformational heterogeneity in cryoEM @ActaCrystD @IUCr #SingleParticleAnalysis #ImageProcessing #CryoEM https://t.co/lS26tWZjRU
    view full post

    June 20, 2023

    11

    6

Abstract Synopsis

  • The Scipion Flexibility Hub is an integrated framework designed to enhance the analysis of conformational heterogeneity in cryo-electron microscopy (cryoEM), allowing researchers to better understand how structure relates to function in biological macromolecules.
  • It addresses the challenge of combining various advanced image processing algorithms by automatically managing communication between different software tools, which simplifies creating flexible workflows for detailed conformational analysis.
  • By streamlining this process, the Flexibility Hub helps maximize the quality and quantity of information obtained from cryoEM data, advancing the study of macromolecular flexibility and dynamics.