November 2023 PMID 37332029

Sustainable Syntheses of Paracetamol and Ibuprofen from Biorenewable β-pinene.

Joshua D Tibbetts, Marc Hutchby, William B Cunningham, Robert S L Chapman, Gabriele Kociok-Köhn, Matthew G Davidson, Steven D Bull

Mentions

74
Peak: 13 in Jul 2023
across 5 sources since Jul 2023

Extended reach

235,338
potential audience

Total likes

6,035

Video views

190,476

Mentions per month

Jul 2023 – Jun 2025

Where it's discussed

  • News45 articles
  • X / Twitter18 posts
  • Blogs6 articles
  • YouTube3 videos
  • Reddit2 posts

AI synopsis

What people are saying

Many discussions emphasize the innovative aspect of using biorenewable pinene to synthesize common pharmaceuticals, as seen in posts that mention 'scalable processes' and the shift from crude oil, reflecting excitement about greener options. The tone combines curiosity and optimism, as illustrated by comments like 'Makes you wonder what is hiding in cannabis' and references to industry advancements, signifying both interest and a belief in the potential impact of this research.

AgreementModerate agreement

Most discussions resonate positively, highlighting the innovative approach and potential benefits, though there is some skepticism about industry implications.

InterestHigh interest

The topic generates high interest, especially due to its environmental significance and potential to replace fossil fuels.

EngagementModerate engagement

Participants actively discuss the methodology, potential applications, and broader implications, showing a moderate level of engagement.

ImpactModerate impact

The discussions suggest recognition of meaningful scientific and environmental impact, though some posts focus more on curiosity than practical consequences.

Abstract in brief

  • Scalable processes have been developed to convert biorenewable pinene into a key intermediate, 4-isopropenylcyclohexanone, which is then used to synthesize sustainable versions of painkillers like paracetamol and ibuprofen.
  • Both synthetic routes involve palladium (Pd) catalyzed reactions that aromatize cyclohexenyl rings, transforming them into benzenoid ring systems found in these drugs.
  • The study also explores the potential use of bioderived 4-hydroxyacetophenone as a sustainable aromatic feedstock within a terpene biorefinery framework, aiming for greener pharmaceutical production.

Top posts

Most liked on X and Bluesky
C Roberts(tweets from a colonised Scotland)
@CRobertsonUK · X

Makes ye wonder what is hiding in cannabis really, that big pharma has prevented for 100 years. https://t.co/leyzA9vkOW

Dec 4, 2023 · 14 likes · 4 shares · 9,379 followers View post →
ChemSusChem
@ChemSusChem · X

Sustainable Syntheses of Paracetamol and Ibuprofen from Biorenewable beta-Pinene (@joshtibbetts, Steven D. Bull and co-workers at @Bathchem and @Leicesterchem) #OpenAccess https://t.co/dXMd5gHqU9

Aug 29, 2023 · 13 likes · 1 share · 8,294 followers View post →
ChemSusChem
@ChemSusChem · X

@wileyinresearch @UniofBath @bioengineerorg @ChemEurope https://t.co/n0mcoVDwp1

Jul 10, 2023 · 3 likes · 1 share · 8,294 followers View post →
Josh Tibbetts
@JoshTibbetts · X

And here’s the link to the original research in @ChemSusChem https://t.co/2KOfVSVVAc

Jul 5, 2023 · 3 likes · 171 followers View post →
新しい天使
@neostenshi · X

【製紙産業廃棄物から鎮痛薬製造に成功】製紙産業副産物であるテレビン油から最も一般的な鎮痛薬イブプロフェンやアセトアミノフェンを製造する方法をバース大学の研究者が開発しました

Jul 9, 2023 · 2 likes · 4,090 followers View post →
Tecnología & Gadgets
@revolutegplus · X

Científicos fabrican ibuprofeno y otros analgésicos comunes a partir de residuos de la industria papelera Investigadores de la Universidad de Bath utilizaron aguarrás para producir precursores químicos. https://t.co/X054rWmadm

Jul 9, 2023 · 2 likes · 3,274 followers View post →

All mentions

Samantha Cole
@samanco253 · X

https://t.co/1aSoi7Ktm7

Jun 10, 2025 · 1 like · 264 followers View post →
Jayfer55
@ferguson2811 · X

RT @CRobertsonUK: Makes ye wonder what is hiding in cannabis really, that big pharma has prevented for 100 years. https://t.co/leyzA9vkOW

Dec 4, 2023 · 4 shares · 4,446 followers View post →
Elaine Callander
@ElaineCallande2 · X

RT @CRobertsonUK: Makes ye wonder what is hiding in cannabis really, that big pharma has prevented for 100 years. https://t.co/leyzA9vkOW

Dec 4, 2023 · 4 shares · 215 followers View post →
Stephen Morrison
@Stephen87386723 · X

RT @CRobertsonUK: Makes ye wonder what is hiding in cannabis really, that big pharma has prevented for 100 years. https://t.co/leyzA9vkOW

Dec 4, 2023 · 4 shares · 1,666 followers View post →
Don Presquivel
@lord_prefab · X

RT @CRobertsonUK: Makes ye wonder what is hiding in cannabis really, that big pharma has prevented for 100 years. https://t.co/leyzA9vkOW

Dec 4, 2023 · 4 shares · 1,176 followers View post →
C Roberts(tweets from a colonised Scotland)
@CRobertsonUK · X

Makes ye wonder what is hiding in cannabis really, that big pharma has prevented for 100 years. https://t.co/leyzA9vkOW

Dec 4, 2023 · 14 likes · 4 shares · 9,379 followers View post →
Analio Dugarte
@analioj · X

RT @ChemSusChem: Sustainable Syntheses of Paracetamol and Ibuprofen from Biorenewable beta-Pinene (@joshtibbetts, Steven D. Bull and co-wor…

Aug 29, 2023 · 1 share · 2,187 followers View post →
ChemSusChem
@ChemSusChem · X

Sustainable Syntheses of Paracetamol and Ibuprofen from Biorenewable beta-Pinene (@joshtibbetts, Steven D. Bull and co-workers at @Bathchem and @Leicesterchem) #OpenAccess https://t.co/dXMd5gHqU9

Aug 29, 2023 · 13 likes · 1 share · 8,294 followers View post →
Miguel Ángel Sogorb
@MASogorb · X

Pinos en vez de petróleo para elaborar paracetamol e ibuprofeno https://t.co/svxq5JFdPC Más información: Sustainable Syntheses of Paracetamol and Ibuprofen from Biorenewable β-pinene https://t.co/kps7IhZIfV

Jul 22, 2023 · 158 followers View post →
Dr. Elizabeth Ndunda
@LizNdunda · X

RT @ChemSusChem: @wileyinresearch @UniofBath @bioengineerorg @ChemEurope https://t.co/n0mcoVDwp1

Jul 10, 2023 · 1 share · 90 followers View post →
ChemSusChem
@ChemSusChem · X

@wileyinresearch @UniofBath @bioengineerorg @ChemEurope https://t.co/n0mcoVDwp1

Jul 10, 2023 · 3 likes · 1 share · 8,294 followers View post →
Dr Oleksandr Kashuba (Clinical Pharmacologist)
@OleksandrKashu2 · X

Sustainable Syntheses of Paracetamol and Ibuprofen from Biorenewable β-pinene https://t.co/7Ay167mvQ7

Jul 10, 2023 · 1 like · 715 followers View post →
Tecnología & Gadgets
@revolutegplus · X

Científicos fabrican ibuprofeno y otros analgésicos comunes a partir de residuos de la industria papelera Investigadores de la Universidad de Bath utilizaron aguarrás para producir precursores químicos. https://t.co/X054rWmadm

Jul 9, 2023 · 2 likes · 3,274 followers View post →
新しい天使
@neostenshi · X

【製紙産業廃棄物から鎮痛薬製造に成功】製紙産業副産物であるテレビン油から最も一般的な鎮痛薬イブプロフェンやアセトアミノフェンを製造する方法をバース大学の研究者が開発しました

Jul 9, 2023 · 2 likes · 4,090 followers View post →
Angshuman 'Moz' Mazumdar
@BinaryVectorJr · X

DOI: https://t.co/mxjVpd4MXy

Jul 9, 2023 · 1 like · 59 followers View post →
Martin Duenas
@duenasm85 · X

Scientists make common pain killers from pine trees instead of crude oil Scalable processes have been developed to convert β-pinene into 4-isopropenylcyclohexanone which is then used as a feedstock for the divergent synthesis of su…https://t.co/nXkVyD2sVG https://t.co/D0h6e35d75

Jul 8, 2023 · 1 like · 81 followers View post →
Vicky Just
@vickyjust · X

@UniofBathNews @Bath_IfS Link to the paper here: https://t.co/7EGUe9rEEl

Jul 6, 2023 · 256 followers View post →
Josh Tibbetts
@JoshTibbetts · X

And here’s the link to the original research in @ChemSusChem https://t.co/2KOfVSVVAc

Jul 5, 2023 · 3 likes · 171 followers View post →