this is so cool guys Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (https://t.co/m6IyLBe4IH) https://t.co/zA6Z3rN7iQ
Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites.
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Jun 2023 – Jul 2025Where it's discussed
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X / Twitter30 posts
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Reddit3 posts
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YouTube2 videos
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Bluesky1 posts
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What people are saying
Overall, discussions around the publication display clear enthusiasm and recognition of its significance, highlighted by comments like 'Still making waves' and 'exciting news,' which emphasize the research's prominence. Tone and word choice suggest respect and admiration for the scientific achievement while primarily focusing on the publication's visibility and accolades rather than critical analysis or detailed scientific implications.
Most discussions acknowledge the significance of the research, with some indicating that the study 'makes waves' and 'is one of the most-viewed articles in the past year,' suggesting general support or recognition of its importance.
There is evident curiosity and enthusiasm, as reflected by comments like 'this is so cool guys' and mentions of the research being 'exciting' and 'making waves,' showing high interest levels.
The engagement is moderate; some posts celebrate the research's acceptance and prize awards, but there is limited detailed discussion or critique of the science itself, indicating surface-level engagement.
The perceived impact is modest; while some posts note the paper's popularity and recognition, there is little indication of discussions about the broader implications or potential changes in research or policy.
Abstract in brief
- The study reports the first enantioselective and scalable total synthesis of mitragynine pseudoindoxyl, a kratom metabolite with fewer side effects compared to traditional opioids, using a novel cascade relay process without protecting groups.
- Researchers found that mitragynine pseudoindoxyl doesn’t act as a single structure but exists as a mixture of stereoisomers in biological environments, showing structural flexibility that could influence its effects.
- These findings lay the groundwork for designing new analogues of mitragynine pseudoindoxyl, which could lead to the development of improved pain-relief medications with better safety profiles.
Top posts
Most liked on X and BlueskyExciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investigation of structural plasticity of these opioid analgesics in biological systems was a remarkable journey. Kudos to the team! https://t.co/5nXNJQLj6P
#TotalSynthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (Tibor Soos and co-workers) @SoosGroup #openaccess https://t.co/LRRzdadHBg
Congratulations Krisz & Peti on your well-deserved prizes at the Organic & Medicinal Chemistry Symposium by BUTE & Hungarian Chemical Society! A big congrats to the other team members for their contributions to the success! https://t.co/OpSuiMAb8H and https://t.co/KJuQsFdgHh https://t.co/uBOeq44bb0
Sauce https://t.co/JcPsPiaNRs
Still making waves: our @angew_chem paper “Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites” was one of the most-viewed articles in the past year!
All mentions
Advances in Organic Synthesis and Kratom Pseudoindoxyl Study
This video discusses five important papers in organic synthesis published in mid-2023. It highlights breakthrough methods like a novel cascade relay process for mitragynine pseudoindoxyl and explores structural…
Advances in Kratom Pseudoindoxyl Metabolite Synthesis and Structural Insights
This episode discusses the total synthesis of mitragynine pseudoindoxyl, a kratom metabolite with fewer side effects. It explores its structural flexibility in biological environments and implications for developing…
@HHSGov @RobertKennedyJr @CDCgov Please develop and ease access to treatments for the #fentanyl crisis and leave much less potent, less dangerous plants like #kratom alone. Don't allow it to become a CI restricted control substance. Respectfully https://t.co/2bUD19Akq2
RT @SoosGroup: Still making waves: our @angew_chem paper “Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites” wa…
Still making waves: our @angewandtechemie.bsky.social paper “Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites” was one of the most-viewed articles in the past year!
Still making waves: our @angew_chem paper “Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites” was one of the most-viewed articles in the past year!
Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites #science #publication #research #publications https://t.co/6whUlf6QbZ
RT @That_Chemist: Sauce https://t.co/JcPsPiaNRs
Sauce https://t.co/JcPsPiaNRs
RT @angew_chem: #TotalSynthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (Tibor Soos and co-workers) @SoosGroup #opena…
RT @angew_chem: #TotalSynthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (Tibor Soos and co-workers) @SoosGroup #opena…
RT @angew_chem: #TotalSynthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (Tibor Soos and co-workers) @SoosGroup #opena…
RT @angew_chem: #TotalSynthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (Tibor Soos and co-workers) @SoosGroup #opena…
RT @angew_chem: #TotalSynthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (Tibor Soos and co-workers) @SoosGroup #opena…
RT @angew_chem: #TotalSynthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (Tibor Soos and co-workers) @SoosGroup #opena…
#TotalSynthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (Tibor Soos and co-workers) @SoosGroup #openaccess https://t.co/LRRzdadHBg
@NaOHBartfield Paywalls are frustrating! Access the article from your library: https://t.co/KUfWAfm1Ub Promote scholarly access when tweeting articles by simply adding https://t.co/SXSePSX5De to the DOI URL
this is so cool guys Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites (https://t.co/m6IyLBe4IH) https://t.co/zA6Z3rN7iQ
RT @SoosGroup: Congratulations Krisz & Peti on your well-deserved prizes at the Organic & Medicinal Chemistry Symposium by BUTE & Hungarian…
RT @SoosGroup: Congratulations Krisz & Peti on your well-deserved prizes at the Organic & Medicinal Chemistry Symposium by BUTE & Hungarian…
RT @SoosGroup: Congratulations Krisz & Peti on your well-deserved prizes at the Organic & Medicinal Chemistry Symposium by BUTE & Hungarian…
Congratulations Krisz & Peti on your well-deserved prizes at the Organic & Medicinal Chemistry Symposium by BUTE & Hungarian Chemical Society! A big congrats to the other team members for their contributions to the success! https://t.co/OpSuiMAb8H and https://t.co/KJuQsFdgHh https://t.co/uBOeq44bb0
Total synthesis and structural plasticity of kratom pseudoindoxyl metabolites https://t.co/0Tu4OLZtsR
Beautiful SI
Total Synthesis and Structural Plasticity of Kratom Pseudoindoxyl Metabolites #science #publication #research #journal https://t.co/N6Yr30npc3
RT @SoosGroup: Exciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investig…
RT @SoosGroup: Exciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investig…
RT @SoosGroup: Exciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investig…
RT @SoosGroup: Exciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investig…
RT @SoosGroup: Exciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investig…
RT @SoosGroup: Exciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investig…
RT @SoosGroup: Exciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investig…
Exciting news! Our research paper on kratom metabolites is now accepted in @angew_chem! The total synthesis and the investigation of structural plasticity of these opioid analgesics in biological systems was a remarkable journey. Kudos to the team! https://t.co/5nXNJQLj6P