Green synthesis of stable hybrid biocatalyst using a hydrogen-bonded, π-π-stacking supramolecular assembly for electrochemical immunosensor.

Wei Huang, Haitao Yuan, Huangsheng Yang, Xiaomin Ma, Shuyao Huang, Hongjie Zhang, Siming Huang, Guosheng Chen, Gangfeng Ouyang

June 2023 Nat Commun

Synopsis of Social media discussions

The discussions highlight the innovative 'green synthesis' approach and its potential for medical diagnostics, with phrases like 'eco-friendly' and 'potential for sensitive medical testing' reflecting positive perceptions. The mention of techniques such as 'hydrogen-bonded, π-π stacking' and 'porous crystal structure' showcase technical interest, while comments about real-world applications indicate a shared belief in the study’s significance.

A
Agreement
 Moderate agreement

Most discussions express agreement or positive acknowledgment of the study's methodology and potential benefits.

I
Interest
 Moderate level of interest

Participants show moderate curiosity, mainly focusing on the eco-friendly approach and biomedical applications.

E
Engagement
 Moderate level of engagement

People reference specific aspects like supramolecular assembly and sensor functionality, indicating a decent level of engagement.

I
Impact
 Moderate level of impact

Discussions suggest that the research could influence future biosensor design and sustainable synthesis practices, implying moderate impact.

Social Mentions

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4 Posts

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Total Likes

8

Extended Reach

518,305

Social Features

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Posts referencing the article

Green Synthesis of Stable Hybrid Biocatalysts for Medical Diagnostics

Green Synthesis of Stable Hybrid Biocatalysts for Medical Diagnostics

This study presents a green method to create a stable hybrid biocatalyst by using supramolecular assembly techniques, which combine enzymes with nanoscaffolds without harsh conditions, making the process environmentally friendly.

STEM RTCL TV

September 29, 2023

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    Green synthesis of stable hybrid biocatalyst using a hydrogen-bonded, π-π-stacking supramolecular assembly for electrochemical immunosensor https://t.co/FQpIel6rDg
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    Green synthesis of stable hybrid biocatalyst using a hydrogen-bonded, π-π-stacking supramolecular assembly for electrochemical immunosensor https://t.co/SSiFKZbdkw https://t.co/2KLhRE4gAU
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Abstract Synopsis

  • This study presents a green method to create a stable hybrid biocatalyst by using supramolecular assembly techniques, which combine enzymes with nanoscaffolds without harsh conditions, making the process environmentally friendly.
  • The researchers use a pyrene-based tecton with formic acid arms to assemble around fragile enzymes, forming a porous crystal structure that protects the enzymes and includes pore channels to improve substrate selectivity.
  • This innovative biocatalyst is applied in an electrochemical immunosensor capable of detecting cancer biomarkers at very low concentrations (pg/mL), demonstrating its potential for sensitive medical diagnostics.