Life Sci Alliance September 2023 PMID 37364915

Transducing compressive forces into cellular outputs in cancer and beyond.

Céline Schmitter, Mickaël Di-Luoffo, Julie Guillermet-Guibert

Mentions

9
Peak: 3 in Jul 2023
across 3 sources since Jun 2023

Extended reach

6,957
potential audience

Total likes

3

Video views

57

Mentions per month

Jun 2023 – Dec 2023

Where it's discussed

  • X / Twitter6 posts
  • Facebook2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The group shows enthusiastic support for the research, citing its focus on how compressive forces influence cancer and normal tissues, with phrases like 'leading to novel treatments' and 'key insights into cellular signaling.' The tone is academic and optimistic, highlighting the potential for translating mechanobiological discoveries into clinical applications, demonstrating deep engagement and belief in its significance.

AgreementStrong agreement

All posts express strong support and recognition of the significance of the research, emphasizing its potential for therapeutic developments.

InterestHigh interest

Discussions reflect high curiosity, with references to novel mechanisms and potential applications in cancer treatment.

EngagementHigh engagement

Posts actively engage with specific aspects such as signaling pathways and cellular responses, showing deep involvement and interest.

ImpactHigh impact

The tone and content suggest that the group perceives the research as highly impactful, with mentions of innovative treatment possibilities and foundational biological insights.

Abstract in brief

  • Cells detect mechanical forces like compression, shear, and tension and convert these signals into biochemical responses, a process called mechanotransduction.
  • Recent research shows that compressive forces can influence not just the directly compressed cells but also neighboring cells, affecting various cell behaviors.
  • Compression plays a role in normal tissue functions like bone healing and in diseases such as intervertebral disc degeneration and cancers, with ongoing studies exploring how it triggers cellular signaling pathways and outcomes.

Top posts

Most liked on X and Bluesky
LifeScienceAlliance
@LSAjournal · X

Identifying selective signaling and cell biology processes induced by mechanical compressive forces can lead to novel treatments for normal or pathological tissue, including tumors @GuillermetLab @CRCT @CNRS @Inserm @FondationARC @ToulouseCancer https://t.co/MoTa7OiFLT https://t.co/CSpAsdWDNT

Jul 4, 2023 · 1 like · 2 shares · 2,647 followers View post →
LifeScienceAlliance
@LSAjournal · X

Interested about how compressive forces selectively transduces into cellular outputs in cancer and beyond, read the latest review from Guillermet-Guibert lab @GuillermetLab @CRCT @CNRS @Inserm @FondationARC @ToulouseCancer https://t.co/yyRyrHizLv https://t.co/iozjnidi05

Jun 27, 2023 · 1 like · 1 share · 2,647 followers View post →
CRCT-Oncopole
@crctoncopole · X

[video] Cancer under pressure: which signals are activated? about the article published in @LSAjournal from @GuillermetLab @crctoncopole https://t.co/6nah4oa3nu

Dec 29, 2023 · 1 like · 1,191 followers View post →
Eric Sawey
@Eric_GenesDev · X

RT @LSAjournal: Identifying selective signaling and cell biology processes induced by mechanical compressive forces can lead to novel treat…

Jul 4, 2023 · 2 shares · 137 followers View post →
Eric Sawey
@Eric_GenesDev · X

RT @LSAjournal: Interested about how compressive forces selectively transduces into cellular outputs in cancer and beyond, read the latest…

Jun 27, 2023 · 1 share · 137 followers View post →
Guillermet's Lab
@GuillermetLab · X

RT @LSAjournal: Identifying selective signaling and cell biology processes induced by mechanical compressive forces can lead to novel treat…

Jul 4, 2023 · 2 shares · 125 followers View post →

All mentions

CRCT-Oncopole
@crctoncopole · X

[video] Cancer under pressure: which signals are activated? about the article published in @LSAjournal from @GuillermetLab @crctoncopole https://t.co/6nah4oa3nu

Dec 29, 2023 · 1 like · 1,191 followers View post →
Eric Sawey
@Eric_GenesDev · X

RT @LSAjournal: Identifying selective signaling and cell biology processes induced by mechanical compressive forces can lead to novel treat…

Jul 4, 2023 · 2 shares · 137 followers View post →
Guillermet's Lab
@GuillermetLab · X

RT @LSAjournal: Identifying selective signaling and cell biology processes induced by mechanical compressive forces can lead to novel treat…

Jul 4, 2023 · 2 shares · 125 followers View post →
LifeScienceAlliance
@LSAjournal · X

Identifying selective signaling and cell biology processes induced by mechanical compressive forces can lead to novel treatments for normal or pathological tissue, including tumors @GuillermetLab @CRCT @CNRS @Inserm @FondationARC @ToulouseCancer https://t.co/MoTa7OiFLT https://t.co/CSpAsdWDNT

Jul 4, 2023 · 1 like · 2 shares · 2,647 followers View post →
Eric Sawey
@Eric_GenesDev · X

RT @LSAjournal: Interested about how compressive forces selectively transduces into cellular outputs in cancer and beyond, read the latest…

Jun 27, 2023 · 1 share · 137 followers View post →
LifeScienceAlliance
@LSAjournal · X

Interested about how compressive forces selectively transduces into cellular outputs in cancer and beyond, read the latest review from Guillermet-Guibert lab @GuillermetLab @CRCT @CNRS @Inserm @FondationARC @ToulouseCancer https://t.co/yyRyrHizLv https://t.co/iozjnidi05

Jun 27, 2023 · 1 like · 1 share · 2,647 followers View post →