A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following: https://t.co/hi0vS3Y4qE Vitamin D toxicity (hypercalcemia) would not manifest levels below 150 ng/mL—Concomitant vitamin K2 (100 micrograms/day) mitigates it
Physiological Basis for Using Vitamin D to Improve Health.
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May 2023 – Oct 2025Where it's discussed
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X / Twitter98 posts
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YouTube2 videos
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What people are saying
The discussions prominently feature emphasis on optimal vitamin D serum levels (such as above 50 or 80 ng/mL) and their health benefits, with users referencing authoritative opinions and specific research findings, demonstrating a strong interest and recognition of potential health impacts. The tone combines supportive statements with practical advice, highlighting the perceived importance of the article’s implications for health improvement and disease prevention.
Most discussions support the importance of maintaining adequate vitamin D levels based on the article’s findings.
The majority of posts display high curiosity, referencing specific serum levels and health implications.
Several users reflect deeply on the research, sharing personal insights, questions, or related studies, indicating active involvement.
There is a shared belief that the research could influence health practices, especially in preventive healthcare and supplementation guidelines.
Abstract in brief
- Vitamin D is crucial for various bodily functions, including metabolism, immune response, and hormone regulation; deficiency increases the risk of diseases like diabetes, cancer, obesity, and infections.
- The enzyme calcitriol (125OHD) interacts with vitamin D receptors (VDRs) in cells to regulate gene expression, influencing health outcomes, with higher serum levels (above 50 ng/mL) needed to mitigate certain health conditions.
- For correcting deficiency, cholecalciferol (Vitamin D3) is preferred, whereas calcifediol works quickly in emergencies; calcitriol is mainly used in cases like renal failure, but other analogs are costly and not recommended for routine supplementation.]
Top posts
Most liked on X and BlueskyThere are a few specific conditions needing higher levels of 25(OH)D than 80 ng/mL: one can review these in the following: https://t.co/oAQXqMRDmk Vitamin D-related toxicity would not manifest below 150 ng/mL—concomitant vitamin K2 (100 micrograms/day) can mitigate it.
Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
Vitamin D For All—Part Five: Vitamin D safety—When should caution be advised? Vitamin D benefits occur over a steep dose response. Beyond that, no additional benefits. This is crucial for Clinical Studies and practice (DOI: 10.3390/biomedicines11061542). https://t.co/3tYdCodbIa
Vitamin D: Ein ausreichender Blutspiegel von über 50 ng/ml sind sehr wichtig für eine umfassende Gesundheit und ein geringes Risiko schwer zu erkranken. Vitamin D ist billiger als nur ein Tag Krankenhausaufenthalt https://t.co/vraR7M8Vkf
Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
All mentions
Optimal Vitamin D Intake for Health and Safety
Discover the importance of adequate vitamin D levels and how to determine your individual needs. The video covers absorption, transport, and key factors affecting vitamin D's role in health, emphasizing safe…
Optimizing Vitamin D Intake for Health and Safety
Discover the importance of sufficient vitamin D supply and how to determine your individual needs. Recent research suggests that the safe upper limit may be lower than previously thought, with doses of 800-1000 IU daily…
Herbstzeit ist die perfekte Zeit, um den Vitamin-D-Spiegel zu testen und ihn bei Bedarf auf den gewünschten Level zu bringen. Quelle: https://t.co/ubpaUXMVCH https://t.co/UKV0f1v099
Physiological Basis for Using Vitamin D to Improve Health by Sunil J. Wimalawansa https://t.co/BvxCAC06lo https://t.co/bNL5XAEz3x
RT @SJWimalawansa: Benefits from “exposure to ultraviolet rays.” Inadequate UV Exposure in Winter is Associated With Higher All-Cause Morta…
RT @SJWimalawansa: Benefits from “exposure to ultraviolet rays.” Inadequate UV Exposure in Winter is Associated With Higher All-Cause Morta…
Benefits from “exposure to ultraviolet rays.” Inadequate UV Exposure in Winter is Associated With Higher All-Cause Mortality. Exposure to UV rays significantly reduces cardiovascular deaths. https://t.co/hi0vS3Y4qE Physiological Basis for Using Vitamin D to Improve Health
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
Base fisiológica para usar la vitamina D para mejorar la salud https://t.co/XVEpXtYObY
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
Part -4 Target 50-60ng/ml to reduce your risk of cancer by 50% You will need 5000-10000iu daily (higher dose for obese, people with health conditions). I recommend vitamin D with turmeric for double protection. https://t.co/ah05yPUxH8 https://t.co/yfKVOoIqXu #vitaminD https://t.co/hKoYyTtuTG
@JesusIs91940818 @ProCuris01 @NIHDirector Read up on vit D. It's key for health. General info https://t.co/9mhpUuoSmf Sun exposure https://t.co/vOTFBoyOWh Physiology of vit D https://t.co/7IB7oZW1R6
@dysclinic https://t.co/7IB7oZW1R6
@Trivium4tw @realpungao "The more D people take the less disease we have, right?" Right. https://t.co/7IB7oZWzGE So, how do we get vit D when we can't get it from the sun?
@dr_cottrell "While various tissues have different thresholds for 25(OH)D concentrations, levels above 50 ng/mL are necessary to mitigate conditions such as infections/sepsis, cancer, and reduce premature deaths." https://t.co/7IB7oZW1R6
@StevenJonMiller @ABridgen https://t.co/7IB7oZWzGE
@MrChemistryMed @bmoschetti @InformedNJNurse very informative overview of vit D & health https://t.co/7IB7oZWzGE
@pwsimerimiaw @zalaly https://t.co/7IB7oZWzGE
@DrIanWeissman https://t.co/7IB7oZW1R6
@ID_Denmark @tlowdon @angie_rasmussen "I agree with her on Ivermectin and Vitamin D." This is why continuing education for MDs will never meet the need to stay current. S Wimalawansa: "Physiological Basis for Using Vitamin D to Improve Health" @SJWimalawansa
@AlanS71420449 @DrSyedHaider Get your vit D levels up. https://t.co/7IB7oZW1R6
@D_Bone There's been a lot of research about vit D in the last ten years that will likely impact chronic issues like Long Covid. Vit D researchers are saying that vit D target levels should be a lot higher than 30 ng/ml for chronic issues. More like 60-80. https://t.co/7IB7oZW1R6
@DocAhmadMalik You might want to follow the author: @SJWimalawansa https://t.co/7IB7oZW1R6
Schematic illustration of generation of #vitamin D and its scalcium/mineral regulatory functions of calcitriol in conjunction with parathyroid hormone (PTH) and fibroblast growth factor-23 (FGF-23) https://t.co/HBLtDAjTST https://t.co/0YKgBz3Lui
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
Physiological Basis for Using Vitamin D to Improve Health Sunil J Wimalawansa. Biomedicines. 2023. Author Sunil J Wimalawansa @SJWimalawansa https://t.co/9ebywGpL4S
RT @MartinMeinung: Vitamin D: Ein ausreichender Blutspiegel von über 50 ng/ml sind sehr wichtig für eine umfassende Gesundheit und ein ger…
RT @MartinMeinung: Vitamin D: Ein ausreichender Blutspiegel von über 50 ng/ml sind sehr wichtig für eine umfassende Gesundheit und ein ger…
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
RT @MartinMeinung: Vitamin D: Ein ausreichender Blutspiegel von über 50 ng/ml sind sehr wichtig für eine umfassende Gesundheit und ein ger…
RT @MartinMeinung: Vitamin D: Ein ausreichender Blutspiegel von über 50 ng/ml sind sehr wichtig für eine umfassende Gesundheit und ein ger…
RT @MartinMeinung: Vitamin D: Ein ausreichender Blutspiegel von über 50 ng/ml sind sehr wichtig für eine umfassende Gesundheit und ein ger…
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
Vitamin D: Ein ausreichender Blutspiegel von über 50 ng/ml sind sehr wichtig für eine umfassende Gesundheit und ein geringes Risiko schwer zu erkranken. Vitamin D ist billiger als nur ein Tag Krankenhausaufenthalt https://t.co/vraR7M8Vkf
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
RT @SJWimalawansa: A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following…
A few conditions need serum 25(OH)D levels higher than 50 ng/mL (range 50-80 ng/mL) For review please read the following: https://t.co/hi0vS3Y4qE Vitamin D toxicity (hypercalcemia) would not manifest levels below 150 ng/mL—Concomitant vitamin K2 (100 micrograms/day) mitigates it
Physiological Basis for Using Vitamin D to Improve Health Sunil J Wimalawansa. Biomedicines. 2023. Author Sunil J Wimalawansa @SJWimalawansa https://t.co/9ebywGpL4S
Physiological Basis for Using Vitamin D to Improve Health Sunil J Wimalawansa. Biomedicines. 2023. Author Sunil J Wimalawansa @SJWimalawansa https://t.co/9ebywGpL4S
@drgurner @BernieSanders Physiological Basis for Using Vitamin D to Improve Health Sunil J Wimalawansa. Biomedicines. 2023. Author Sunil J Wimalawansa @SJWimalawansa https://t.co/BmdFF7NWLG
RT @BogdanBugibu: @PBeatap Jeszcze 'wczoraj' za takie poglądy zostawało się szurem, negacjonistą, denialistą i propagatorem antynauki. http…
Physiological Basis for Using Vitamin D to Improve Health Sunil J Wimalawansa. Biomedicines. 2023. Author Sunil J Wimalawansa @SJWimalawansa https://t.co/7nLRgN0bfx
RT @pamiechomeblog: "Istnieje kilka specyficznych schorzeń wymagających wyższych poziomów 25 (OH) D niż 80 ng/ml: https://t.co/jjlHb6Sz02…
RT @pamiechomeblog: "Istnieje kilka specyficznych schorzeń wymagających wyższych poziomów 25 (OH) D niż 80 ng/ml: https://t.co/jjlHb6Sz02…
@PBeatap Jeszcze 'wczoraj' za takie poglądy zostawało się szurem, negacjonistą, denialistą i propagatorem antynauki. https://t.co/5BCT6gZI0a https://t.co/Zs3nV8b5Yl
RT @SJWimalawansa: There are a few specific conditions needing higher levels of 25(OH)D than 80 ng/mL: one can review these in the followin…
RT @Shahin20634947: @DrDeborahMD @HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @hirokazupapi @JuhanaHarju @DrPalmquist @shashiiy…
RT @pamiechomeblog: "Istnieje kilka specyficznych schorzeń wymagających wyższych poziomów 25 (OH) D niż 80 ng/ml: https://t.co/jjlHb6Sz02…
"Istnieje kilka specyficznych schorzeń wymagających wyższych poziomów 25 (OH) D niż 80 ng/ml: https://t.co/jjlHb6Sz02 Toksyczność związana z witaminą D nie objawia się poniżej 150 ng/ml – jednoczesna witamina K2 (100 mikrogramów/dzień) może ją złagodzić." #profilaktykaD3 https://t.co/GbIfTnABNu
RT @SJWimalawansa: There are a few specific conditions needing higher levels of 25(OH)D than 80 ng/mL: one can review these in the followin…
@DrDeborahMD @HealthyFellow @_atanas_ @_INPST @ScienceCommuni2 @DHPSP @hirokazupapi @JuhanaHarju @DrPalmquist @shashiiyengar @erlesen Physiological Basis for Using Vitamin D to Improve Health Sunil J Wimalawansa. Biomedicines. 2023. Author Sunil J Wimalawansa @SJWimalawansa https://t.co/BmdFF7NWLG
RT @SJWimalawansa: There are a few specific conditions needing higher levels of 25(OH)D than 80 ng/mL: one can review these in the followin…
RT @SJWimalawansa: There are a few specific conditions needing higher levels of 25(OH)D than 80 ng/mL: one can review these in the followin…
RT @SJWimalawansa: There are a few specific conditions needing higher levels of 25(OH)D than 80 ng/mL: one can review these in the followin…
There are a few specific conditions needing higher levels of 25(OH)D than 80 ng/mL: one can review these in the following: https://t.co/oAQXqMRDmk Vitamin D-related toxicity would not manifest below 150 ng/mL—concomitant vitamin K2 (100 micrograms/day) can mitigate it.
"However, the minimum level to be maintained to overcome infections, cancer, autoimmunity, and _heart disease_ and for robust immunity is 50 ng/mL" https://t.co/7IB7oZW1R6
@NicotineLozeng @Argus88Ate @drnathimdladla https://t.co/7IB7oZW1R6
@RubberDucky333 @SJWimalawansa https://t.co/7IB7oZWzGE
RT @SJWimalawansa: Vitamin D For All—Part Five: Vitamin D safety—When should caution be advised? Vitamin D benefits occur over a steep dose…
RT @SJWimalawansa: Vitamin D For All—Part Five: Vitamin D safety—When should caution be advised? Vitamin D benefits occur over a steep dose…
RT @SJWimalawansa: Vitamin D For All—Part Five: Vitamin D safety—When should caution be advised? Vitamin D benefits occur over a steep dose…
RT @SJWimalawansa: Vitamin D For All—Part Five: Vitamin D safety—When should caution be advised? Vitamin D benefits occur over a steep dose…
Vitamin D For All—Part Five: Vitamin D safety—When should caution be advised? Vitamin D benefits occur over a steep dose response. Beyond that, no additional benefits. This is crucial for Clinical Studies and practice (DOI: 10.3390/biomedicines11061542). https://t.co/3tYdCodbIa
@rsvpatients Physiological Basis for Using Vitamin D to Improve Health https://t.co/AwHiOlxthe #mdpibiomedicines via @Biomed_MDPI https://t.co/3HHzP4J7R9
@Ayurveda_Speaks @SanatanTalks @AyurvedaTalks @Its_Me_Jasraj @jaishree___ @Krishnavallabhi Physiological Basis for Using Vitamin D to Improve Health https://t.co/luuosBdait #mdpibiomedicines via @Biomed_MDPI https://t.co/VSHkTUsF7q
@P_J_Buckhaults Lots of studies of immune mechanisms of vit D over the past 10 years. Lots of vit D receptors in most tissues. Lots of implications for infectious disease/cancer/autoimmune/chronic disease. Overview here from a leading researcher. https://t.co/7IB7oZW1R6
@hazardscampaign @JoePajak It's kind of obvious that you don't favor supplementing with vitamin D. Maybe you aren't up on research? https://t.co/7IB7oZW1R6
@rickman3a @aftab_usa Here's one...not on a supplement manufacturer's website tho https://t.co/7IB7oZW1R6
@UEGJournal @joostphdrenth @omar_elshaarawy @LumirKunovsky @KralJan @aelsharkawy75 @MajaThiele Physiological Basis for Using Vitamin D to Improve Health https://t.co/AwHiOlxthe #mdpibiomedicines via @Biomed_MDPI https://t.co/3HHzP4J7R9
Physiological Basis for Using Vitamin D to Improve Health https://t.co/XVEpXtYObY
@SurpriseSparrow @hrefnask Meh, I read and reflect. Being elderly, neither my skin production of vit D nor gut uptake are topnotch, so I need more than 20k units that a youngster's skin would produce. The following current article is helpful. https://t.co/7IB7oZW1R6
Source for 1st quotation: /3 https://t.co/7IB7oZW1R6
@CAREPakistan_ Physiological Basis for Using Vitamin D to Improve Health https://t.co/ufCPJZlyOH #mdpibiomedicines via @Biomed_MDPI https://t.co/KJUJXpijHe
@WHOEMRO @WHOTunisia @PmTunisia Physiological Basis for Using Vitamin D to Improve Health https://t.co/AwHiOlxthe #mdpibiomedicines via @Biomed_MDPI https://t.co/3HHzP4J7R9
RT @SJWimalawansa: Physiological basis for using vitamin D to enhance human health. The most cost-effective way to reduce chronic illnesses…
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
RT @Orlando_uy: Physiological Basis for Using Vitamin D to Improve Health https://t.co/J0o6WEZe3i #mdpibiomedicines a través de @Biomed_MDPI
Physiological Basis for Using Vitamin D to Improve Health https://t.co/J0o6WEZe3i #mdpibiomedicines a través de @Biomed_MDPI
RT @wbgrant2: Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
Physiological Basis for Using Vitamin D to Improve Health https://t.co/3nkXubYM0k #mdpibiomedicines via @Biomed_MDPI
Physiological Basis for Using Vitamin D to Improve Health https://t.co/aqqNZeelFi #mdpibiomedicines via @Biomed_MDPI
RT @Shahin75247020: Physiological Basis for Using Vitamin D to Improve Health https://t.co/UbuZXgN3iz #mdpibiomedicines via @Biomed_MDPI
Treating nutrient deficiencies (e.g., vitamin D, etc.) to overcome conditions requires understanding biology and physiology in conjunction with practicalities and cost-effectiveness. Expensive analogus are restricted to specific indications only. https://t.co/vag8R7fxga
RT @SJWimalawansa: Physiological basis for using vitamin D to enhance human health. The most cost-effective way to reduce chronic illnesses…
RT @SJWimalawansa: Physiological basis for using vitamin D to enhance human health. The most cost-effective way to reduce chronic illnesses…
RT @SJWimalawansa: Physiological basis for using vitamin D to enhance human health. The most cost-effective way to reduce chronic illnesses…
RT @SJWimalawansa: Physiological basis for using vitamin D to enhance human health. The most cost-effective way to reduce chronic illnesses…
Physiological Basis for Using Vitamin D to Improve Health https://t.co/UbuZXgN3iz #mdpibiomedicines via @Biomed_MDPI
Physiological basis for using vitamin D to enhance human health. The most cost-effective way to reduce chronic illnesses and healthcare costs. Biomedicines 11, 1542. 2023. https://t.co/rcGbdJ3tsW https://t.co/hi0vS3Y4qE
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