Nat Commun June 2023 PMID 37391398

Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop.

Tengyan Xu, Jiaqi Wang, Shuang Zhao, Dinghao Chen, Hongyue Zhang, Yu Fang, Nan Kong, Ziao Zhou, Wenbin Li, Huaimin Wang

Mentions

5
Peak: 2 in Jun 2023
across 2 sources since Jun 2023

Extended reach

518,986
potential audience

Total likes

9

Video views

21

Mentions per month

Jun 2023 – Oct 2023

Where it's discussed

  • X / Twitter4 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions demonstrate strong support and enthusiasm for the article's innovative approach, with phrases like 'accelerating discovery' and expressions of pride, highlighting the perceived importance of combining experimental work with machine learning for peptide hydrogel prediction. The tone is positive and optimistic, emphasizing the work's potential to advance the field.

AgreementModerate agreement

The discussions reflect general support and acknowledgment of the article’s significance, especially with phrases like 'Glad to see our work is online now' indicating positive recognition.

InterestHigh interest

Interest is high, as participants highlight the innovative approach of combining experimental data with machine learning in peptide hydrogel prediction.

EngagementModerate engagement

Comments show active engagement through sharing excitement and enthusiasm, though they mainly focus on appreciation rather than critical analysis.

ImpactModerate impact

The discussions suggest a moderate perception of impact, recognizing the potential significance of accelerating discovery processes, but without extensive debate on broader implications.

Abstract in brief

  • The amino acid sequences of peptides are crucial for determining their ability to form hydrogels, but predicting this accurately has been difficult.
  • This study showcases a method that combines experimental data with machine learning to enhance the prediction and design of peptide hydrogels, synthesizing over 160 natural tetrapeptides for testing.
  • By creating a comprehensive score function and an extensive sequence library, they achieved an impressive 87.1% success rate in predicting hydrogel formation, which also demonstrated enhanced immune responses in a SARS-CoV-2 model.

Top posts

Most liked on X and Bluesky
Chemistry News
@ChemistryNews · X

Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop https://t.co/BOUXfzeHmt https://t.co/uv7WKwTmb8

Jun 30, 2023 · 8 likes · 2 shares · 517,822 followers View post →
Huaimin Wang
@whmeagle · X

Glad to see our work is online now! Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop @NatureComms https://t.co/ipAd4VpZMF

Jul 1, 2023 · 1 like · 166 followers View post →
//bPunkProTOCol//\|\|_|_|_~_\___ \/ |\\
@cw4t7abs · X

RT @ChemistryNews: Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop https://t.co/BOUXfzeHmt https://t.…

Jul 3, 2023 · 2 shares · 920 followers View post →
BeABa
@infoalcupom · X

RT @ChemistryNews: Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop https://t.co/BOUXfzeHmt https://t.…

Jun 30, 2023 · 2 shares · 45 followers View post →

All mentions

//bPunkProTOCol//\|\|_|_|_~_\___ \/ |\\
@cw4t7abs · X

RT @ChemistryNews: Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop https://t.co/BOUXfzeHmt https://t.…

Jul 3, 2023 · 2 shares · 920 followers View post →
Huaimin Wang
@whmeagle · X

Glad to see our work is online now! Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop @NatureComms https://t.co/ipAd4VpZMF

Jul 1, 2023 · 1 like · 166 followers View post →
BeABa
@infoalcupom · X

RT @ChemistryNews: Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop https://t.co/BOUXfzeHmt https://t.…

Jun 30, 2023 · 2 shares · 45 followers View post →
Chemistry News
@ChemistryNews · X

Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop https://t.co/BOUXfzeHmt https://t.co/uv7WKwTmb8

Jun 30, 2023 · 8 likes · 2 shares · 517,822 followers View post →