PubHawk
Mil Med Res July 2023 PMID 37460924

Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges.

Bashdar Mahmud Hussen, Mohammed Fatih Rasul, Snur Rasool Abdullah, Hazha Jamal Hidayat, Goran Sedeeq Hama Faraj, Fattma Abodi Ali, Abbas Salihi, Aria Baniahmad, Soudeh Ghafouri-Fard, Milladur Rahman, Mark C Glassy, Wojciech Branicki, Mohammad Taheri

Full text PDF Download social card

Mentions

9
Peak: 4 in Jul 2023
across 3 sources since Jul 2023

Extended reach

19,115
potential audience

Total likes

0

Video views

23

Mentions per month

Jul 2023 – Oct 2023

Where it's discussed

  • X / Twitter5 posts
  • Facebook3 posts
  • YouTube1 videos

AI synopsis

What people are saying

Discussions reflect a cautious optimism about the potential of CRISPR/Cas in targeting miRNAs for cancer treatment, with mentions of challenges like safety and off-target effects. The tone is analytical, referencing broader implications such as the relevance to personalized medicine and the ongoing scientific debates about the methods, which contribute to a balanced view of the article's significance.

AgreementModerate agreement

Most discussions agree that CRISPR/Cas targeting of miRNA holds promise for cancer therapy, though some express skepticism about challenges or broader implications.

InterestModerate interest

Posters show a moderate interest, highlighting the relevance of the research but not exhibiting intense enthusiasm.

EngagementModerate engagement

Comments demonstrate some depth by referencing mechanisms, potential applications, and challenges, indicating a thoughtful engagement.

ImpactNeutral impact

The perceived impact is somewhat recognized, but posts do not strongly emphasize transformative or widespread influence.

Abstract in brief

  • CRISPR-Cas technology has revolutionized cancer research by enabling precise editing of the genome, including noncoding RNAs like microRNAs (miRNAs), which play critical roles in tumor development and heterogeneity.
  • The application of CRISPR-Cas for targeting miRNAs offers promising opportunities for developing personalized and effective cancer therapies, but it also faces challenges such as ensuring safety, avoiding off-target effects, and designing optimal strategies for gene editing.
  • The study discusses innovative approaches and potential solutions to these challenges, emphasizing the importance of careful design and advanced techniques to safely harness CRISPR-Cas for miRNA-based cancer treatments.]
Read the full abstract

Top posts

Most liked on X and Bluesky
World Stem Cell Summit
@WSCSummit · X

Research: Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges. https://t.co/MhINUoblCN

Jul 18, 2023 · 12,215 followers View post →
James V. Kohl
@microRNApro · X

"Military Medical Research" https://t.co/0Hk3jpYbBc 7/17/23 suggests the world is at war with stem cell researchers, like @exosome, who refuse to link the ATP-dependent Creation of RNA in regulatory T cells to prevention of all virus-driven pathology across kingdoms via #RNAi.

Jul 18, 2023 · 2,566 followers View post →
CRISP_SCIENCE
@ScienceCrisp · X

REVIEW "Targeting miRNA by #CRISPR/Cas in cancer: advantages and challenges" Hussen BM, Rasul MF [..] Branicki W, Taheri M. Military Med Res 2023-07-17. https://t.co/gPWL49BqqO

Jul 27, 2023 · 1,917 followers View post →
Dr. Elden Wayne Whalen III, ShD
@wayne_effect · X

https://t.co/aMdJ7gC7uw

Aug 25, 2023 · 1,267 followers View post →

All mentions

Dr. Elden Wayne Whalen III, ShD
@wayne_effect · X

https://t.co/aMdJ7gC7uw

Aug 25, 2023 · 1,267 followers View post →
CRISP_SCIENCE
@ScienceCrisp · X

REVIEW "Targeting miRNA by #CRISPR/Cas in cancer: advantages and challenges" Hussen BM, Rasul MF [..] Branicki W, Taheri M. Military Med Res 2023-07-17. https://t.co/gPWL49BqqO

Jul 27, 2023 · 1,917 followers View post →
Lee J. Keller
@leejkeller · X

Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges - Military Medical Research https://t.co/shS3IV0RrX

Jul 18, 2023 · 1,128 followers View post →
World Stem Cell Summit
@WSCSummit · X

Research: Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges. https://t.co/MhINUoblCN

Jul 18, 2023 · 12,215 followers View post →
James V. Kohl
@microRNApro · X

"Military Medical Research" https://t.co/0Hk3jpYbBc 7/17/23 suggests the world is at war with stem cell researchers, like @exosome, who refuse to link the ATP-dependent Creation of RNA in regulatory T cells to prevention of all virus-driven pathology across kingdoms via #RNAi.

Jul 18, 2023 · 2,566 followers View post →