Ann Neurol November 2023 PMID 37466404

Abnormal Glutamatergic and Serotonergic Connectivity in Visual Snow Syndrome and Migraine with Aura.

Francesca Puledda, Ottavia Dipasquale, Benjamin J M Gooddy, Nazia Karsan, Ray Bose, Mitul A Mehta, Steven C R Williams, Peter J Goadsby

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Mentions

Peak: 8 in Aug 2023

across 5 sources since Jul 2023

Extended reach

48,778

potential audience

Total likes

554

Video views

13,976

Mentions per month

Jul 2023 – Aug 2025

Where it's discussed

X / Twitter21 posts
News6 articles
Reddit3 posts
YouTube2 videos
Facebook2 posts

AI synopsis

What people are saying

The social discussions reflect interest through mentions of biological mechanisms such as the glutamatergic and serotonergic networks, with some posts speculating about links to severe visual snow symptoms, showing engaged, thoughtful reactions. The tone emphasizes the importance of the findings, contributing to a broader understanding of the condition without overly emotional language.

AgreementModerate agreement

Most discussions acknowledge the study’s findings, with some noting its support for biological explanations of Visual Snow Syndrome, indicating a general agreement.

InterestHigh interest

The discussions exhibit high interest, as many posts discuss the implications of the research and its connection to conditions like migraine with aura.

EngagementModerate engagement

Participants seem engaged, referencing specific neurotransmitter networks and highlighting the significance of the findings, though the interactions are mainly informational.

ImpactModerate impact

The study appears to have a moderate impact, with several posts emphasizing its contribution to understanding Visual Snow Syndrome but not yet translating into widespread clinical change.

Abstract in brief

The study aimed to understand the neuropharmacological changes in visual snow syndrome (VSS) by using receptor target maps and resting fMRI to identify involved neurotransmitters.*
Researchers compared functional connectivity (FC) in patients with VSS, healthy controls, and migraine patients, finding reduced FC in glutamatergic and serotonergic networks specifically in VSS patients.*
The findings suggest that altered glutamate and serotonin connectivity in VSS might share similarities with migraine with aura, indicating a possible shared biological mechanism between the two conditions.*

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All mentions

Brain Chemical Differences in Visual Snow Syndrome Revealed by New Study

This research supported by the Visual Snow Initiative investigates neurochemical changes in VSS, highlighting differences in glutamate and serotonin activity that could lead to future treatments.

Visual Snow Initiative · Aug 25, 2023 7,823 views

Brain Imaging Reveals Biological Factors in Visual Snow Syndrome

This study examines neuropharmacological changes in visual snow syndrome using receptor maps and resting fMRI, finding reduced glutamate and serotonin connectivity in VSS patients, suggesting a shared biological…

Visual Snow Initiative · Aug 23, 2023 6,153 views

rina

@r1nainhell · X

@kepe__ https://t.co/lIZDnYhFaH (here's the link smh)

Aug 13, 2025 · 1 like · 579 followers View post →

Vishal Mehta

@docvishalmehta · X