Nat Med August 2023 PMID 37488288

Pig-to-human heart xenotransplantation in two recently deceased human recipients.

Nader Moazami, Jeffrey M Stern, Karen Khalil, Jacqueline I Kim, Navneet Narula, Massimo Mangiola, Elaina P Weldon, Larisa Kagermazova, Les James, Nikki Lawson, Greta L Piper, Philip M Sommer, Alex Reyentovich, Daniel Bamira, Tajinderpal Saraon

Mentions

47
Peak: 31 in Jul 2023
across 5 sources since Jul 2023

Extended reach

85,740
potential audience

Total likes

1,071

Video views

11,621

Mentions per month

Jul 2023 – Apr 2025

Where it's discussed

  • X / Twitter34 posts
  • News6 articles
  • Facebook3 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

Discussions show strong support for the significance of pig-to-human heart transplants, referring to them as 'important steps' and 'moving the field forward,' with some emphasizing the potential impact on transplantation practices. Words like 'game changer' and references to scientific advances highlight high interest and recognition of the research's importance.

AgreementModerate agreement

Most discussions seem supportive or optimistic about the research, highlighting its significance.

InterestHigh interest

The discussions show high interest, with many emphasizing the breakthrough nature of these experiments.

EngagementModerate engagement

Many participants are engaging with comments about potential, methods, and implications, indicating active interest.

ImpactHigh impact

The overall tone suggests this research could be a game changer in transplant medicine, thus highly impactful.

Abstract in brief

  • Genetically modified pigs are being explored as a solution to the shortage of human organs available for transplantation.
  • In a study, porcine hearts were transplanted into two brain-dead human recipients, showing good cardiac function initially, although one heart had a decline due to size mismatch.
  • The research confirmed no immediate immune rejection or disease transmission from pigs to humans, suggesting that pig-to-human heart transplants could be viable with further development.

Top posts

Most liked on X and Bluesky
Pon|食と健康
@PonNutr · X

10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 66 likes · 20 shares · 2,624 followers View post →
Alex Reyentovich, MD
@ReyentovichHFMD · X

Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human recipients | Nature Medicine. ⁦@nyugrossman⁩ ⁦@nyulangone⁩ https://t.co/jcQcPnQiXB

Jul 24, 2023 · 44 likes · 7 shares · 935 followers View post →
Katalin Susztak
@KSusztak · X

Pig-to-human heart xenotransplantation in two recently deceased human recipients | ⁦@NatureMedicine⁩ ⁦@NYUnephro⁩ https://t.co/IGWcrUWMI9

Jul 25, 2023 · 27 likes · 4 shares · 7,006 followers View post →
Rob Shaffer
@ShafferBiotech · X

More work needs to be done but... wow. Pig-to-human heart xenotransplantation in two recently deceased human recipients https://t.co/jKx4MWV146 @NatureMedicine

Jul 26, 2023 · 1 like · 1,002 followers View post →
ASHI HLA
@ASHIHQ · X

New ASHI Insights: Pig-to-human heart xenotransplantation in two recently deceased human recipients Read here: https://t.co/xmAoOtdnO3 Circulating cell-free methylated DNA reveals tissue-specific, cellular damage from radiation treatment Read Here: https://t.co/a8Ejj1BfC1 https://t.co/mNx3Pof8Lx

Feb 1, 2024 · 1 like · 1 share · 654 followers View post →
Sunil V. Rao
@SVRaoMD · X

RT @ReyentovichHFMD: Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human reci…

Jul 24, 2023 · 7 shares · 31,042 followers View post →

All mentions

Memorias de Dolly
@memoriasdedolly · X

https://t.co/zwj37wq0Lu

Apr 13, 2025 · 235 followers View post →
cathi murphey
@cmurphey18 · X

RT @ASHIHQ: New ASHI Insights: Pig-to-human heart xenotransplantation in two recently deceased human recipients Read here: https://t.co/…

Feb 1, 2024 · 1 share · 32 followers View post →
ASHI HLA
@ASHIHQ · X

New ASHI Insights: Pig-to-human heart xenotransplantation in two recently deceased human recipients Read here: https://t.co/xmAoOtdnO3 Circulating cell-free methylated DNA reveals tissue-specific, cellular damage from radiation treatment Read Here: https://t.co/a8Ejj1BfC1 https://t.co/mNx3Pof8Lx

Feb 1, 2024 · 1 like · 1 share · 654 followers View post →
Life Science Journal Content
@lsn_jc · X

Pig-to-human heart xenotransplantation in two recently deceased human recipients #science #publication #research #journal https://t.co/yJQwxUXxiN

Jul 31, 2023 · 263 followers View post →
RRID Robot
@RobotRrid · X

RRIDs were included in the Nature Medicine paper "Pig-to-human heart xenotransplantation in two rece…" (https://t.co/5nDxswGbv1). Thank you for making your #methodsmatter. #reproducibility

Jul 30, 2023 · 161 followers View post →
Tree flog
@tkms_h · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 27, 2023 · 20 shares · 101 followers View post →
やまぐちだいすけ | 諸般?の事情で夏休み大幅延長中
@yamagu09 · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 260 followers View post →
田舎者(天草地方出身者)
@imoame0801 · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 1,347 followers View post →
め
@hayo_kaeri_tai · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 108 followers View post →
DeepTechDr
@ProgenBioTechCo · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 157 followers View post →
Hiromi Matsumae
@hmat_evo · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 1,015 followers View post →
Homam Ibrahim MD FACC
@homam_heartdoc · X

RT @ReyentovichHFMD: Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human reci…

Jul 26, 2023 · 7 shares · 193 followers View post →
Rob Shaffer
@ShafferBiotech · X

More work needs to be done but... wow. Pig-to-human heart xenotransplantation in two recently deceased human recipients https://t.co/jKx4MWV146 @NatureMedicine

Jul 26, 2023 · 1 like · 1,002 followers View post →
市村 ハリー
@HariIchimura · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 1,098 followers View post →
K
@N92022058 · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 2 followers View post →
プロトン(ワクチン6回接種済)
@5sPgm · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 574 followers View post →
Daiki Nagatomo
@Dyechan_6x · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 386 followers View post →
K.Koiwai
@KKo1wa1 · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 1,099 followers View post →
hmap
@hmap01337406 · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 742 followers View post →
know thyself(子豚のオリバー)
@thyself_know · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 1,223 followers View post →
DGG
@DGG7334 · X

RT @KSusztak: Pig-to-human heart xenotransplantation in two recently deceased human recipients | ⁦@NatureMedicine⁩ ⁦@NYUnephro⁩ https://t.…

Jul 26, 2023 · 4 shares · 113 followers View post →
a
@ayanosatoh · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 623 followers View post →
baramonia
@baramonia · X

RT @Pon_yurublog: 10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 20 shares · 1,421 followers View post →
Pon|食と健康
@PonNutr · X

10ヶ所ゲノム編集をしたブタの心臓を2人の脳死患者に移植し、拒絶反応や感染のない成功例をまとめたNat medの論文 https://t.co/dLd34HTdcf

Jul 26, 2023 · 66 likes · 20 shares · 2,624 followers View post →
Edoardo Melilli
@EdoardoMelilli · X

RT @KSusztak: Pig-to-human heart xenotransplantation in two recently deceased human recipients | ⁦@NatureMedicine⁩ ⁦@NYUnephro⁩ https://t.…

Jul 25, 2023 · 4 shares · 3,262 followers View post →
Tony Martín
@Tonymartincasti · X

RT @KSusztak: Pig-to-human heart xenotransplantation in two recently deceased human recipients | ⁦@NatureMedicine⁩ ⁦@NYUnephro⁩ https://t.…

Jul 25, 2023 · 4 shares · 354 followers View post →
Dimitris Mastellos
@dmastellos · X

RT @KSusztak: Pig-to-human heart xenotransplantation in two recently deceased human recipients | ⁦@NatureMedicine⁩ ⁦@NYUnephro⁩ https://t.…

Jul 25, 2023 · 4 shares · 589 followers View post →
Katalin Susztak
@KSusztak · X

Pig-to-human heart xenotransplantation in two recently deceased human recipients | ⁦@NatureMedicine⁩ ⁦@NYUnephro⁩ https://t.co/IGWcrUWMI9

Jul 25, 2023 · 27 likes · 4 shares · 7,006 followers View post →
Barry Fine
@BarryFine1 · X

RT @ReyentovichHFMD: Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human reci…

Jul 25, 2023 · 7 shares · 93 followers View post →
Maryjane Farr MD MSc, FACC FAST FHFSA FAHA
@MaryjaneFarrMD · X

RT @ReyentovichHFMD: Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human reci…

Jul 25, 2023 · 7 shares · 2,580 followers View post →
Matt Daniels MD PhD
@cardiacpolymath · X

RT @ReyentovichHFMD: Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human reci…

Jul 25, 2023 · 7 shares · 2,988 followers View post →
Sunil V. Rao
@SVRaoMD · X

RT @ReyentovichHFMD: Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human reci…

Jul 24, 2023 · 7 shares · 31,042 followers View post →
Jason N. Katz
@JasonKatzMD · X

RT @ReyentovichHFMD: Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human reci…

Jul 24, 2023 · 7 shares · 9,056 followers View post →
Alex Reyentovich, MD
@ReyentovichHFMD · X

Important step in moving the field forward. Pig-to-human heart xenotransplantation in two recently deceased human recipients | Nature Medicine. ⁦@nyugrossman⁩ ⁦@nyulangone⁩ https://t.co/jcQcPnQiXB

Jul 24, 2023 · 44 likes · 7 shares · 935 followers View post →